Effects of meat consumption and vegetarian diet on risk of wrist fracture over 25 years in a cohort of peri- and postmenopausal women     

Thorpe DL  Knutsen SF  Beeson WL  Rajaram S  Fraser GE 《Public health nutrition》2008,11(6):564-572

BACKGROUND: Evidence suggesting that a diet high in fruits and vegetables may be beneficial to bone health has sparked interest in the potential benefit of a vegetarian diet. However, other studies have raised a question regarding the adequacy of protein in such a diet. OBJECTIVE: The aim of the present study was to take a whole foods approach in examining the effects of foods high in protein on the risk of wrist fracture (WF) in a cohort with a significant proportion consuming a meat-free diet. DESIGN: A cohort study of women who completed two lifestyle surveys 25 years apart. SUBJECTS: One thousand eight hundred and sixty-five peri- and postmenopausal women at the time of the first survey. RESULTS: There was a significant interaction between meat consumption and foods high in vegetable protein. Among vegetarians, those who consumed the least vegetable protein intake were at highest risk for fracture. However, increasing levels of plant-based high-protein foods decreased WF risk, with a 68% reduction in risk (hazard ratio (HR) = 0.32, 95% confidence interval (CI) 0.13-0.79) in the highest intake group. Among those with lowest vegetable protein consumption, increasing meat intake decreased the risk of WF, with the highest consumption decreasing risk by 80% (HR = 0.20, 95% CI 0.06-0.66). CONCLUSIONS: The finding that higher consumption frequencies of foods rich in protein were associated with reduced WF supports the importance of adequate protein for bone health. The similarity in risk reduction by vegetable protein foods compared with meat intake suggests that adequate protein intake is attainable in a vegetarian diet.  相似文献   

Soil risk maps – Interpreting soils data for policy makers,agencies and industry     

Nikki Baggaley  Allan Lilly  Kirsty Blackstock  Karen Dobbie  Adam Carson  Fraser Leith 《Soil Use and Management》2020,36(1):19-26

Surface runoff, erosion, compaction and the leaching of potential pollutants from land can degrade the soil resource and damage the water environment, reducing crop yields, causing loss of valuable nutrients and organic matter, together with increasing flood risk. Increasingly, it is recognized that scientific information must be translated into practical tools to change practices and protect the soil and water resource. Working alongside agencies in Scotland, we applied a suite of simple, transparent, rule-based models to identify areas most at risk of exporting sediment and pollutants that may degrade water quality based on field-scale (1:25,000) soil maps. The maps have been used by Scottish Environment Protection Agency, Scottish Water and Scottish Government to assess soil risks to waters from field to regional scale. The work brought scientists together with policy makers, agencies and the water industry to pool their knowledge to apply these practical tools for decision-making. It highlights the need to apply existing knowledge to answer salient questions. All three examples described show that providing the right type of information, which is based on fundamental soils data, can directly influence the implementation of policies, investment and monitoring decisions and provide evidence in support of government. However, this requires both researchers and agency scientists to develop skills as knowledge brokers and to normalize the use of soil data in everyday agency settings.  相似文献   

Outbreak of cryptosporidiosis among veterinary students     

Gait R  Soutar RH  Hanson M  Fraser C  Chalmers R 《The Veterinary record》2008,162(26):843-845

In January 2007, six veterinary students became infected with Cryptosporidium species, and records indicated that another student had been diagnosed in November 2006. It was established that the seven students had worked with cattle from the same farm. Microbiological tests indicated that they were infected with Cryptosporidium parvum. Subtyping by sequence analysis indicated a common source of infection for five of the students, but there was insufficient material to type the other two samples. Investigations indicated that the outbreak was caused by a lapse in hygiene, particularly handwashing, on a farm with enzootic C parvum in calves.  相似文献   

Successful surgical management of an Escherichia coli epidural–subdural abscess secondary to sino‐rhinotomy     

Angharad B. Simlett‐Moss  Alistair Freeman  Fraser J. McConnell  Richard Coe  Daniel Sanchez‐Masian 《Journal of Veterinary Emergency and Critical Care》2019,29(6):696-701

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Ultrasonographic evaluation of vitreous degeneration in normal dogs.     

Julien J Labruyère  Claudia Hartley  Katherine Rogers  Graham Wetherill  J Fraser McConnell  Ruth Dennis 《Veterinary radiology & ultrasound》2008,49(2):165-171

Vitreous degeneration is common in dogs and may be associated with cataract formation. Vitreous degeneration may be identified using B-mode ultrasonography and appears as multiple, small, motile, point-like echoes within the vitreous cavity. In humans, vitreous degeneration has also been observed in normal aging eyes but the incidence of vitreous degeneration in dogs without cataract has not previously been documented. The purpose of this study was to describe the ultrasonographic appearance of vitreous degeneration and to investigate its incidence in a population of dogs without cataract or other apparent eye disease. The eyes of 62 dogs were evaluated as part of a prospective study. All dogs underwent ophthalmological and ultrasonographic examinations and vitreal changes were graded on ultrasonography using a predetermined grading scheme. Vitreous degeneration was found in 20% (23/114) of the eyes on ultrasonographic examination but in only 8% (9/114) of eyes on direct ophthalmoscopy. Sensitivity and specificity of ophthalmoscopy using ultrasonography as a gold standard were respectively, 39% and 100%. Vitreal syneresis and asteroid hyalosis could be distinguished according to their ultrasonographic characteristics. The probability of having vitreous degeneration increased with the age of the dog (odds ratio = 6.7 for dogs of 7 + years compared with 0-6 years) and also increased in females compared with males (odds ratio = 3.6). Vitreous degeneration, especially mild vitreal syneresis, is not uncommon in normal dogs; it was shown to be an age-related condition and its significance should not be overinterpreted on ocular ultrasonography.  相似文献   

Magnetic resonance imaging features of spinal epidural empyema in five dogs.     

Alberta De Stefani  Laurent S Garosi  Fraser J McConnell  Francisco J Llabres Diaz  Ruth Dennis  Simon R Platt 《Veterinary radiology & ultrasound》2008,49(2):135-140

Spinal epidural empyema is defined an accumulation of purulent material in the epidural space of the vertebral canal. Spinal epidural empyema should be considered as a differential diagnosis in dogs with pyrexia, spinal pain, and rapidly progressing myelopathy. Magnetic resonance (MR) imaging is the imaging test of choice in humans. Here, we describe the MR imaging features of five dogs with confirmed spinal epidural empyema. The epidural lesions appeared as high or mixed signal masses in T2-weighted (T2W) images. Increased signal within the spinal cord gray matter at the site of the lesion was detected in T2W images in all dogs. Two patterns of enhancement were detected on postcontrast T1-weighted (T1W) images. Mild to moderate peripheral enhancement was seen in three dogs and a diffuse pattern of enhancement was seen in one. Discospondylitis was identified in three dogs on T1W postcontrast images. Decompressive spinal surgery was performed in all dogs. Bacteria isolated from the abnormal epidural tissue were Enterobacter cloacae, coagulase-positive Staphylococci, Pasteurella multocida, and Escherichia coli. In one dog bacteria were not isolated. These MR imaging features, along with appropriate clinical signs, can allow prompt diagnosis and appropriate treatment planning.  相似文献   

Tuberculosis in deer: another piece in the unfinished Mycobacterium bovis jigsaw     

Menzies F 《Veterinary journal (London, England : 1997)》2008,175(3):287-288

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Retrobulbar teratoma causing exophthalmos in a cat     

Wray JD  Doust RT  Fraser McConnell  Dennis RT  Blunden AS 《Journal of Feline Medicine and Surgery》2008,10(2):175-180

A 3-year female-neutered domestic shorthair cat presenting with exophthalmos and an ipsilateral subzygomatic soft tissue mass lesion is described. Magnetic resonance imaging of the mass was performed followed by complete surgical excision. The mass was determined to be a retrobulbar teratoma and complete resection was curative. Teratomas are rare germ-cell tumours that uncommonly form in extragonadal sites. A retrobulbar location has not been previously reported in the cat and should be considered a rare cause of exophthalmos in this species.  相似文献   

The benefits of cooling boar semen in long‐term extenders prior to cryopreservation on sperm quality characteristics          下载免费PDF全文

K Wasilewska  Ł Zasiadczyk  L Fraser  M Mogielnicka‐Brzozowska  W Kordan 《Reproduction in domestic animals》2016,51(5):781-788

This study investigated the effects of long‐term extenders on post‐thaw sperm quality characteristics following different holding times (HT) of boar semen at 17 and 10°C. Sperm‐rich fractions, collected from five boars, were diluted in Androhep^® Plus (AHP), Androstar^® Plus (ASP), Safecell^® Plus and TRIXcell^® Plus (TCP) extenders. The extended semen samples were held for 2 hr at 17°C (HT 1) and additionally for 24 hr at 10°C (HT 2), after they were evaluated and frozen. CASA sperm motility and motion patterns, mitochondrial membrane potential (MMP), plasma membrane integrity (PMI) and normal apical ridge (NAR) acrosome integrity were assessed in the pre‐freeze and frozen‐thawed semen. The Vybrant Apoptosis Assay Kit was used to analyse the proportions of viable and plasma membrane apoptotic‐like changes in spermatozoa. Results indicated that boar variability, extender and HT significantly affected the sperm quality characteristics, particularly after freezing‐thawing. Differences in the pre‐freeze semen were more marked in the sperm motion patterns between the HTs. Pre‐freeze semen in HT 2 showed significantly higher VCL and VAP, whereas no marked effects were observed in the sperm membrane integrity and viability (YO‐PRO‐1^?/PI^?) among the extenders. Post‐thaw sperm TMOT and PMOT were significantly higher in the AHP and ASP extenders of HT 2 group, whereas VSL, VCL and VAP were markedly lower in the TCP extender. Furthermore, spermatozoa from the AHP‐ and ASP‐extended semen of HT 2 group were characterized by higher MMP, PMI and NAR acrosome integrity following freezing‐thawing. In most of the extenders, the incidence of frozen‐thawed spermatozoa with apoptotic‐like changes was greater in HT 1. The findings of this study indicate that holding of boar semen at 10°C for 24 hr in long‐term preservation extenders modulates post‐thaw sperm quality characteristics in an extender‐dependent manner. These results will further contribute to the improvement in the cryopreservation technology of boar semen.  相似文献   

The palaeoecological approach to reconstructing former grazing–vegetation interactions     

Richard Bradshaw  Fraser J. G. Mitchell   《Forest Ecology and Management》1999,120(1-3):3-12

Interactions between grazing animals and vegetation are assessed from three temporal perspectives: millions, thousands and hundreds of years. Data abundance and quality are highest for recent time periods, but geological data provide a background to the understanding of present-day grazing–vegetation interactions. The Quaternary glaciations and recent anthropogenic influences have contributed to the loss of European mega-herbivores. The geological record from the Eemian interglacial in Denmark suggests that presence of elephant and rhinoceros did not create widespread openings in forest cover. Large populations of giant deer in Ireland became extinct 11 000 years ago. We propose a theory that the giant deer were sufficiently abundant to convert juniper scrub communities into open grassland at a regional scale. The balance between grazers and browsers has undergone continuous change during the last 10 000 years with significant consequences for forest composition and structure. Hunting statistics and archival records permit crude reconstructions of population dynamics for certain ungulate species. High resolution pollen analysis and long-term monitoring generate reconstructions of vegetation that can be compared with fluctuating grazing pressure during the last few hundred years. Such data can be used to validate simulation models of grazing–vegetation interactions.  相似文献