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Serna-Saldivar SO Zorrilla R De La Parra C Stagnitti G Abril R 《Plant foods for human nutrition (Dordrecht, Netherlands)》2006,61(3):121-129
Different sources of DHA and/or n-3 (omega-3) rich oils, oil emulsions and microencapsulated (ME) powders were tested at two different concentrations with the aim of producing fortified pan bread. Three oils (S-algae, fish and flax), two emulsified algae oils (Emulsion-P and Emulsion-L) and two ME oils (ME-S algae and ME-C algae) were compared. The DHA and n-3 oils replaced part of the shortening in order to obtain 32 g slices enriched with 25 or 50 mg DHA, 35 or 70 mg total n-3 from fish oil and 90 or 180 mg linolenic from flax oil. Addition of oils did not significantly affect water absorption but reduced mix time whereas addition of the ME oils decreased both water absorption and mix time. Breads enriched with flax or ME-C oils had lower volume and higher density than the control, ME-S algae, Emulsion-P and Emulsion-L breads. All breads lost texture throughout 14 d storage, the major changes occurred after 3 d. The ME-S algae oil bread had the best softness after 14 d storage whereas breads produced from ME-S algae or ME-C algae oils had the poorest texture. Sensory evaluations indicated that the color of the ME-S algae oil fortified bread was significantly less preferred than the other loaves. After 6 d the control bread had higher acceptability compared with the rest of the breads enriched with high levels of DHA or omega-3 oils. The high-enriched fish oil bread was well accepted during the first days of storage but had the least preferred acceptability after 13 d. The best fortified breads were those supplemented with S-algae oil, Emulsion-P and Emulsion-L oils. 相似文献
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GEORGE R. GREEN 《Growth and change》1972,3(2):36-39
As the science of econometrics becomes more sophisticated, its practice also becomes more expensive, and attention needs increasingly to be directed to the exploration of possible shortcuts and cost-sharing arrangements. The Executive Director, Short-Tern Forecasting, Wharton Econometric Forecasting Associates, believes that one answer lies in exploiting the decreasing cost characteristics of the econometric forecasting industry. In this paper, he demonstrates how a model designed for national forecasting can be put to state and regional uses. 相似文献
106.
H. DWIGHT MERCER GEORGE E. HEATH PATRICIA E. LONG DAVID H. SHOWALTER THOMAS E. POWERS 《Journal of veterinary pharmacology and therapeutics》1978,1(1):19-36
Eighteen non-fasted, 12–16 week old pigs weighing between 20 and 40 kg were dosed with chloramphenicol intravenously at a dose rate of 22 mg/kg body weight. The pharmacokinetics of chloramphenicol were determined in blood plasma and sixteen selected organs and body fluids. The elimination half-life in plasma was estimated to be 2.66pL1.06 h and volume of distribution was 1.39pL0.32 I/kg. The body clearance of chloramphenicol was estimated to be 6.64pL1.52 ml/kg/min. The elimination half-life in tissue was found to range from 1.25 h in kidney to 5.89 h in fat. Most major organs ranged from 2.0 to 5.0 h. Significant correlations were found to exist between plasma concentrations and most major organ concentrations. Chloramphenicol concentrations in muscle, spleen, lung, stomach content, and large intestine content were found to exist slightly beyond the time when concentrations were negative in plasma. However, urine levels exceeded tissue levels at the last slaughter interval. It appears that serum or urine would be a good body fluid for monitoring chloramphenicol residues in tissues, whereas stomach content might be used as an indicator for chloramphenicol treatment for many days after therapy with the drug. 相似文献
107.
GEORGE S. MARTIN D.V.M. C. WAYNE McILWRAITH B.V.Sc Ph.D. M.R.C.V.S. 《Veterinary surgery : VS》1981,10(4):149-152
A large, bony protuberance from the frontal bone of a horse was found radiographically to communicate with the frontal sinus and to be similar in appearance. The mass was removed surgically, and the communicating defect with the sinus was repaired using synthetic mesh. Recovery was uncomplicated. 相似文献
108.
BRIAN S. GROSSMAN D.V.M. M.S. BARRIE D. GRANT D.V.M. M.S. RONALD D. SANDE D.V.M. PH.D. † MARC H. RATZLAFF D.V.M. PH.D. ‡ ANTHONY M. GALLINA D.V.M. PH.D. § GEORGE BAGBY M.D. M.S. | STEVE PYRITZ B.S.M.E.H ¶ 《Veterinary surgery : VS》1980,9(3):93-102
A prosthesis designed to partially replace the articular surfaces of the radial and third carpal bones was implanted bilaterally in 6 normal horses. The prosthesis consisted of a convex metal alloy component, and a concave ultra-high molecular weight polyethylene component, for implantation into the radial and third carpal bones, respectively. One horse underwent the soft tissue approach only to serve as a control. Effects on joint motion and pathologic changes were monitored over a 6-month period using clinical examination, synovial fluid analysis, electrogoniometry, high-speed cinematography, radiography, and gross and microscopic pathologic examination. Six months following implantation, all horses that received implants would trot, with slight to moderate lameness. Electrogoniometric and cinematographic evaluation of joint motion demonstrated a reduction in amplitude of the carpus in 4 horses receiving implants; however, in 2 horses, the reduction was less than, or equivalent to, that of the control horse. One horse that received the prosthesis was rideable, and was able to run with minimal lameness. Radiography, synovial fluid analysis, and gross and microscopic pathologic examination revealed varying degrees of synovitis and osteoarthritis. Biomechanical alterations of the middle carpal joint and release of wear particles from the prosthesis were considered to be major causes of these secondary changes. Changes in design of the prosthesis, intended to more accurately maintain normal joint biomechanics are proposed. 相似文献
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Results of Transsphenoidal Hypophysectomy in 52 Dogs With Pituitary-Dependent Hyperadrenocorticism 总被引:2,自引:0,他引:2
BJÖRN P. MEIJ DVM PhD Diplomate ECVS GEORGE VOORHOUT DVM PhD Diplomate ECVDI TED S.G.A.M. VAN DEN INGH DVM PhD Diplomate ECVP HERMAN A.W. HAZEWINKEL DVM PhD Diplomate ECVS ERIK TESKE DVM PhD Diplomate ECVIM AD RIJNBERK DVM PhD Diplomate ECVIM 《Veterinary surgery : VS》1998,27(3):246-261
Objective —To evaluate microsurgical transsphenoidal hypophysectomy in dogs with pituitary-dependent hyperadrenocorticism (PDH). Study Design —Prospective study to evaluate the results (survival and disease-free interval, remission, recurrence) and complications of microsurgical transsphenoidal hypophysectomy by clinical follow-up, computed tomography (CT), and urinary corticoid-to-creatinine (C/C) ratios in dogs with PDH. The effect of surgical experience was investigated by comparing results of hypophysectomy cases 1 through 26 and 27 through 52. Animals or Sample Population—52 dogs with PDH. Results —Preoperative CT enabled accurate assessment of pituitary size (24 nonenlarged and 28 enlarged) and localization relative to intraoperative anatomic landmarks. Treatment failures included procedure-related mortalities (five dogs) and incomplete hypophysectomies (four dogs). The 1-year estimated survival rate was 84% (95% confidence interval [CI], 71% to 92%). The 2-year estimated survival rate was 80% (95% CI, 65% to 90%). In 43 dogs, the hyperadrenocorticism went into remission. Hyperadrenocorticism recurred in five dogs. The 1-year estimated relapse-free fraction was 92% (95% CI, 76% to 97%). The main complications were transient, mild, postoperative hypernatremia; transient reduction or cessation of tear production (25 eyes in 18 dogs); permanent (five dogs) or prolonged (nine dogs) diabetes insipidus; and secondary hypothyroidism. Normal tear production had resumed in all but one case after a median period of 10 weeks. In the second case series (27 through 52), the hospitalization period was shorter, the number of dry eyes fewer, the survival fraction greater, and the postoperative mortality lower than in the first series. In 15 dogs in which remission was obtained, postoperative CT images suggested the presence of small pituitary remnants; in 1 of these, hyperadrenocorticism recurred. In 46 dogs, the histological diagnosis was pituitary adenoma. Conclusions —Microsurgical transsphenoidal hypophysectomy in dogs with PDH is an effective method of treatment in specialized veterinary institutions having access to advanced pituitary imaging techniques. Postoperative CT findings do not correlate well with remission or subsequent recurrence of hyperadrenocorticism. Clinical Relevance —The neurosurgeon performing hypophysectomies must master a learning curve and must be familiar with the most frequent complications of the operation to recognize them as early as possible and to treat them immediately and effectively. Urinary C/C ratios are sensitive indicators for the assessment of remission and recurrence of hyperadrenocorticism. 相似文献