Clinical Use of Fatty Acid Supplements in Dogs   总被引：1，自引：0，他引：1  

KAREN L. CAMPBELL 《Veterinary dermatology》1993,4(4):167-173

Abstract— Fatty acids in membrane phospholipids are metabolized by cellular enzymes into a variety of eicosanoids that function in the regulation of normal physiology and serve as mediators of inflammation. Fatty acid supplements can alter the types of eicosanoids produced. Many investigations using fatty acids in the treatment of nutritional deficiencies, seborrhea, atopic dermatitis, cardiovascular, neoplastic, ocular and musculoskeletal diseases of dogs have been conducted over the past decade. Additional studies are needed to determine the optimal levels of linoleic acid, gamma-linolenic acid and/or eicosapentaneoic acid in the diets of dogs for the maintenance of normal homeostasis and for the treatment of inflammatory, degenerative and neoplastic diseases.  相似文献   

A technique for the photography of surface morphology of bacterial colonies     

RJ CAMPBELL 《Australian veterinary journal》1989,66(9):303-304

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Evaluation of dressings to aid healing of mulesing wounds on sheep     

GW. LEVOT  PB. HUGHES  CJ. KALDOR 《Australian veterinary journal》1989,66(11):358-361

Five proprietary and one experimental dressing were compared with no treatment in their ability to aid healing of mulesing wounds in over 1900 young lambs. Healing was judged as the completeness of shrinkage of the mulesing cuts and the condition of scabs on the new skin surface. When assessed at 21 d it was found that treatment with Heriots Crown Wound Powder or Coopers Mulesing Powder offered a significant advantage over leaving the wounds untreated. Neither aqueous organophosphate washes, Defiance nor Defiance containing 0.08% chlorfenvinphos offered any healing advantage over controls. However, washing the wounds with an aqueous organophosphate solution aided healing more than the Defiance-based dressings. It was considered that the powders or the washes encouraged quick scab formation either by creating a dry covering (powders) or by washing away blood and allowing fast drying of the wound. The Defiance-type dressings slowed healing by keeping the wound moist for up to 10 d, but healing was not significantly different to the untreated group by 21 d.  相似文献   

DIAGNOSIS OF PREGNANCY IN SHEEP USING ULTRASONIC COMPOUND SCANNING     

E. A. CAMPBELL Ph.D.  M.A.  B.Sc.  F.R.C.V.S.    M. HERVE  A. T. BELL B.V.Sc. 《Australian veterinary journal》1969,45(1):40-40

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SPINAL NEMATODIASIS OF THE DOG ASSOCIATED WITH ANCYLOSTOMA CANINUM   总被引：1，自引：0，他引：1  

T. D. BUICK  R. S. F. CAMPBELL  G. W. HUTCHINSON 《Australian veterinary journal》1977,53(12):602-603

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Growth of body weight and manipulation of food motivation     

KAPLAN M  CAMPBELL SL  JOHNSON L  PAPAMICHAEL A  SPARER R  WEINBAUM M 《Science (New York, N.Y.)》1959,129(3364):1673-1674

Consideration was given to the possible use of individual growth curves to estimate ad libitum-feeding weights as part of technique for producing specified degrees of food deprivation. In heterozygous animals, this possibility was found to be feasible but limited by the occurrence of discontinuous growth functions.  相似文献   

A survey of granulomatous and neoplastic diseases of equine skin in north Queensland     

S. I. MILLER  R. S. F. CAMPBELL 《Australian veterinary journal》1982,59(2):33-37

SUMMARY A survey of granulomatous and neoplastic diseases of the skin of horses of tropical north Queensland was carried out during the period 1970–1980. Of 338 horses affected, 46.4% suffered from equine fibrosarcoma (sarcoid), 30.2% from phycomycosis, 7.4% from squamous cell carcinoma, 6.8% from other tumours, 4.7% from cutaneous habronemiasis and 4.4% from exuberant granulation tissue. Most specimens were submitted during the first half of the year after the wet monsoonal season and significantly more diseases originated during the first quarter. There were minor variations with breed, age and sex susceptibility between each disease group. Most lesions were found on the legs and head although other parts of the body were also affected. The size and anatomical distribution of lesions varied with each disease. When the results of this survey were compared with reports from southern Queensland as well as from Florida and the United Kingdom, major differences between localities were observed. Some reasons for these differences are discussed.  相似文献   

Biologic activity of dirlotapide, a novel microsomal triglyceride transfer protein inhibitor, for weight loss in obese dogs     

J. A. WREN  V. L. KING  S. L. CAMPBELL  & M. A. HICKMAN 《Journal of veterinary pharmacology and therapeutics》2007,30(S1):33-42

Dirlotapide is a novel microsomal triglyceride transfer protein inhibitor intended for the treatment and management of obesity in dogs. The biologic effects of dirlotapide, weight loss, decreased food intake, increased fecal fat, decreased serum cholesterol, and body composition, were evaluated in a controlled, blinded study. Sixteen obese beagles were randomized to treatment with placebo ( n  = 4) or dirlotapide ( n  = 12) following a 2-week acclimation period in which baseline data were collected. The dirlotapide dose, adjusted to produce weight loss for 3 months and then stabilize body weight for 1 month (weight management), produced a significant difference (expressed as a percentage of baselines) in weekly weight loss, food intake, fecal fat, serum cholesterol concentration, and body composition (measured by dual energy X-ray absorptiometry) compared with placebo treatment ( P  < 0.05). The initial dirlotapide dosage of 0.5 mg/kg (10 times the initial label dose) resulted in a high rate of weight loss (3.3% weekly) and anorexia, emesis, and loose stools for some dogs. A 25% dose reduction (mean dosage: 0.36 mg/kg) followed by biweekly 25% dose adjustments based on individual weight loss, produced 1–2% weekly weight loss and total weight loss of 18.8% in 12 weeks at a final mean dosage of 0.41 mg/kg (range: 0.15–0.60); a dosage range of 0.10–0.34 mg/kg stabilized body weight. Body weight changes for placebo-treated dogs were −0.8% to +0.9% weekly; total weight gain during the weight loss phase was 10.6%. No apparent change in food intake, percentage of fecal fat, and serum cholesterol was observed in the placebo group. Food intake and body weight increased when dirlotapide was discontinued. Dirlotapide produced weight loss by both reducing appetite (about 90% of the weight loss activity) and by increasing fecal fat excretion (about 10% of the weight loss activity).  相似文献   

The soil solution in a soil treated with digested sewage sludge     

DUNCAN J. CAMPBELL  P. H. T. BECKETT 《European Journal of Soil Science》1988,39(2):283-298

Toxic trace metals may percolate to the ground water from sewage sludge disposed onto land. Analyses are presented of the soil solution from a slightly acid loamy soil treated 7 years earlier with single applications of digested sewage sludge in amounts equivalent to 0, 150 & 330 t dry matter ha⁻¹
These very heavy dressings correspond to 2 & 4.5 times the recommended 30–year limit. Samples of soil and soil solution from four depths to 80 cm were analysed for Al, B, Ba, Ca, Cl, Cu, Fe, K, Li, Mg, Mn, Na, Ni, P, S, Sr, V, Zn, together with the OM of the soil, and the pH, alkalinity, dissolved organic carbon, and absorbance at 350 nm of the solutions.
These very heavy sludge applications were apparently still releasing substantial quantities of NO₃, and some SO₄ even after 7 years. Nitrate, SO₄, Mg, Ca, Sr, B, and possibly Ba are still moving through the profile, possibly to the ground water. Solution concentrations of Cu and Zn are considerably higher at all depths than those in the untreated plot, but they fall off sharply with depth. It is unlikely that any Cu or Zn is now reaching the ground water.
The paper also presents a set of published solution analyses for soils, sludge–treated soils and digested sludge, as a basis for further studies.  相似文献   

Cyromazine resistance detected in Australian sheep blowfly     

GW Levot 《Australian veterinary journal》2012,90(11):433-437

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