Production of an epidermal growth factor receptor-related protein   总被引：24，自引：0，他引：24  

W Weber  G N Gill  J Spiess 《Science (New York, N.Y.)》1984,224(4646):294-297

Human epidermoid carcinoma A431 cells in culture produce a soluble 105-kilodalton protein which, by the criteria of epidermal growth factor (EGF) binding, recognition by monoclonal and polyclonal antibodies to the EGF receptor, amino-terminal sequence analysis and carbohydrate content, is related to the cell surface domain of the EGF receptor. The high rate of production and the finding that with biosynthetic labeling the specific activity of this 105-kilodalton protein exceeds that of the intact receptor indicate that it is not derived from membrane-bound mature receptor but is separately produced by the cell. These cells thus separately synthesize an EGF receptor that is inserted into the membrane and an EGF receptor-related protein that is secreted.  相似文献   

Revisiting the taxonomic impediment     

de Carvalho MR  Bockmann FA  Amorim DS  de Vivo M  de Toledo-Piza M  Menezes NA  de Figueiredo JL  Castro RM  Gill AC  McEachran JD  Compagno LJ  Schelly RC  Britz R  Lundberg JG  Vari RP  Nelson G 《Science (New York, N.Y.)》2005,307(5708):353

  相似文献   

FINANCIAL REPORT OF THE PERMANENT SECRETARY     

Gill HA 《Science (New York, N.Y.)》1917,45(1165):416

  相似文献   

湖南省麦迪卡药石农业应用效果综述     

李睿  刘军鸽  李元沅  曹树德  陈广文 《湖南农业科学》2007,(6):120-122

湖南省麦迪卡药石(MEDCAL STONE)资源丰富,质量优良,具有富硅、富钾、富微量元素和离子轻稀土的特点,具有很强的吸附性能,可溶出多种有益矿物质,增加水中氧的含量,调节水的pH值,生物活性强,对防治疾病具有重要作用。经过近20 a的研究,农业上应用在作物施肥、药膳食疗等方面,均有极好的社会、经济效益。同时,产地水土、森林、人文资源特好,生态景观优美,不但是天然的无公害农业基地,也是发展休闲农业、旅游农业的"风水宝地"。  相似文献   

Predatory Dinosaurs from the Sahara and Late Cretaceous Faunal Differentiation     

PC Sereno  DB Dutheil  M Iarochene  HCE Larsson  GH Lyon  PM Magwene  CA Sidor  DJ Varricchio  JA Wilson 《Science (New York, N.Y.)》1996,272(5264):986-991

Late Cretaceous (Cenomanian) fossils discovered in the Kem Kem region of Morocco include large predatory dinosaurs that inhabited Africa as it drifted into geographic isolation. One, represented by a skull approximately 1.6 meters in length, is an advanced allosauroid referable to the African genus Carcharodontosaurus. Another, represented by a partial skeleton with slender proportions, is a new basal coelurosaur closely resembling the Egyptian genus Bahariasaurus. Comparisons with Cretaceous theropods from other continents reveal a previously unrecognized global radiation of carcharodontosaurid predators. Substantial geographic differentiation of dinosaurian faunas in response to continental drift appears to have arisen abruptly at the beginning of the Late Cretaceous.  相似文献   

Inheritance and physiological basis for 2,4-D resistance in prickly lettuce (Lactuca serriola L.)     

Riar DS  Burke IC  Yenish JP  Bell J  Gill K 《Journal of agricultural and food chemistry》2011,59(17):9417-9423

Experiments were conducted to determine the inheritance and physiological basis for resistance to the synthetic auxinic herbicide (2,4-dichlorophenoxy)acetic acid (2,4-D) in a prickly lettuce biotype. Inheritance of 2,4-D resistance in prickly lettuce is governed by a single codominant gene. Absorption and translocation were conducted using (14)C-2,4-D applied to 2,4-D-resistant and -susceptible biotypes. At 96 h after treatment (HAT), the resistant biotype absorbed less applied 2,4-D and retained more 2,4-D in the treated portion of the leaf compared to the susceptible biotype. The resistant biotype translocated less applied 2,4-D to leaves above the treated leaf and crown at 96 HAT compared to the susceptible biotype. No difference in the rate of metabolism of 2,4-D was observed between the two biotypes. Resistance to 2,4-D appears to originate from a reduced growth deregulatory and overstimulation response compared to the susceptible biotype, resulting in lower translocation of 2,4-D in the resistant prickly lettuce biotype.  相似文献   

Phosphate availability from phosphate rock as related to nitrogen form and the nitrification inhibitor DMPP   总被引：1，自引：0，他引：1  

Rahmatullah  Maqsood A. Gill  Alexander H. Wissemeier  Diedrich Steffens 《植物养料与土壤学杂志》2006,169(5):675-678

  相似文献   

Determination of mercury methylation rates using A 203-HG radiotracer technique     

M. C. Stordal  G. A. Gill 《Water, air, and soil pollution》1995,80(1-4):725-734

A radiotracer method for the determination of mercury (Hg) methylation rates in bulk water and water overlying intact sediment cores has been developed. A sediment core with overlying water is collected in a core tube, the overlying water is spiked with high specific activity 203-Hg radiotracer, and the core is incubated at ambient temperature. Aliquots of the overlying water are removed, the Hg is extracted from the sample, and the activity in the extract is measured. A 10–25 fold sample preconcentration is achieved using a dithizone-chloroform extraction technique and a sodium nitrite back extraction step to separate inorganic Hg(II) from monomethylmercury (MMHg). The use of this technique, in conjunction with high specific activity 203-Hg, has allowed for spiking concentrations in the overlying water of approximately 1 ng Hg/L. This spiking level is about the same concentration as the ambient water overlying the core, thus not significantly perturbing the system. Our technique is a significant improvement over previous methodologies which used 203-Hg spike additions of 1 μg Hg/L or higher. The technique was used to measure Hg methylation rates at the Experimental Lakes Area (ELA) in Ontario, Canada during August of 1993 and at an extensively studied estuarine site in Gulf Breeze, Florida, USA during September, 1993 and June, 1994. Multiple cores were collected and spiked with a range of 1 to 11,800 ng Hg (as 203-Hg) into the overlying water. MMHg production at the ELA site indicated rates of 0.25 to 3.7 pg/cm²/day (0.08 to 2.5 % methylation/day). Results from Gulf Breeze were significantly higher at 1.5 to 425 pg/cm²/day or 0.06 to 18 % methylation/day. These rates are one to three orders of magnitude greater than previously measured “specific rates” in bulk water samples and sediments. A direct comparison of rates with previous sediment methylation assay techniques is not possible, however, because of the significant differences between our methodology and previous assay protocols.  相似文献   

Taxing food: implications for public health nutrition     

Caraher M  Cowburn G 《Public health nutrition》2005,8(8):1242-1249

  相似文献   

Enzyme activities and microbial community structure in semiarid agricultural soils   总被引：15，自引：0，他引：15  

Acosta-Martínez  V.  Zobeck  T. M.  Gill  T. E.  Kennedy  A. C. 《Biology and Fertility of Soils》2003,38(4):216-227

This study investigated the effect of management on -glucosidase, -glucosaminidase, alkaline phosphatase, and arylsulfatase activities and the microbial community structure in semiarid soils from West Texas, USA. Surface samples (0–5 cm) were taken from a fine sandy loam, sandy clay loam, and loam that were under continuous cotton ( Gossypium hirsutum L.) or in cotton rotated with peanut ( Arachis hypogaea L.), sorghum ( Sorghum bicolor L.), rye ( Secale cereale) or wheat ( Triticum aestivum L.), and had different water management (irrigated or dryland), and tillage (conservation or conventional). The enzyme activities were higher in the loam and sandy clay loam than in the fine sandy loam. Soil pH was not affected by management, but the soil organic C and total N contents were generally affected by the different crop rotations and tillage practices studied. The trends of the enzyme activities as affected by management depended on the soil, but in general crop rotations and conservation tillage increased the enzyme activities in comparison to continuous cotton and conventional tillage. The soil enzyme activities were significantly correlated with the soil organic C ( r -values up to 0.90, P< 0.001), and were correlated among each other ( r -values up to 0.90, P <0.001). There were differences in the fatty acid methyl ester profiles between the fine sandy loam and the sandy clay loam and loam, and they reflected the differences in the enzyme activities found among the soils. For example, a 15:0 ranged from 1.61±0.25% in cotton-peanut/irrigated/no-till in the fine sandy loam to 3.86±0.48% in cotton-sorghum/dryland/conservation tillage in the sandy clay loam. There were no differences due to management within the same soil.Trade names and company names are included for the benefit of the reader and do not infer any endorsement or preferential treatment of the product by USDA-ARS  相似文献