Association between Waste Management and Cancer in Companion Animals     

L. Marconato  C. Leo  R. Girelli  S. Salvi  F. Abramo  G. Bettini  S. Comazzi  P. Nardi  F. Albanese  E. Zini 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2009,23(3):564-569

Background: Increased cancer rates have been documented in people residing in areas around Naples characterized by illegal dumping and incineration of waste.
Hypothesis: Risk of cancer in dogs and cats is associated with waste management.
Animals: Four hundred and fifty-three dogs and cats with cancer and 1,554 cancer-free animals.
Methods: Hospital-based case-control study in Naples (low danger) and nearby cities having a history of illegal waste dumping (high danger). Odds ratio (OR) between high- and low-danger areas was calculated for all tumors and various malignancies in dogs and cats.
Results: An increased risk for cancer development was identified in dogs but not in cats residing in high-danger areas (OR: 1.55; 95% confidence interval: 1.18–2.03; P < .01). A 2.39-fold increased risk of lymphoma ( P < .01) accounted for the greater tumor frequency in dogs residing in high-danger areas. The risk of mast cell tumor and mammary cancer did not differ in dogs residing in high- or low-danger areas.
Conclusions and Clinical Importance: Waste emission from illegal dumping sites increases cancer risk in dogs residing in high-danger areas. An increased prevalence of lymphoma has been previously recognized in humans living close to illegal waste dumps. Thus, epidemiological studies of spontaneous tumors in dogs might suggest a role for environmental factors in canine and human carcinogenesis and can predict health hazards for humans.  相似文献   

An atypical case of respiratory actinobacillosis in a cow     

Peli Angelo  Spadari Alessandro  Romagnoli Noemi  Bettini Giuliano  Scarpa Filippo  Pietra Marco 《Journal of veterinary science (Suw?n-si, Korea)》2009,10(3):265-267

A not pregnant 4-year-old Jersey cow was presented with the sudden appearance of respiratory noise, nasal discharge and moderate respiratory difficulty. Upon physical examination a snoring-like noise, extended head and neck position, exaggerated abdominal effort, bilateral nasal discharge and left prescapular lymph node enlargement were noted. Sub-occlusion of the initial portion of the respiratory tract was suspected. Radiographic and endoscopic examinations revealed a pedunculate mass on the dorsal aspect of the rhinopharynx, which was removed with endoscopically assisted electrosurgery. Histologic examination revealed a chronic pyogranulomatous inflammation with eosinophilic club-like bodies surrounding small colonies of rod-shaped bacteria. Results of histochemical staining were consistent with Actinobacillus-like bacteria and a diagnosis of respiratory actinobacillosis was reached. Surgery and antibiotic therapy were resolutive, as demonstated by an endoscopic check at the second month after surgery, even without the association of the traditional iodine cure, which is regarded as the treatment of choice for actinobacillosis.  相似文献   

Bile duct dysplasia and congenital hepatic fibrosis associated with polycystic kidney (Caroli syndrome) in a rat   总被引：1，自引：0，他引：1  

Bettini G  Mandrioli L  Morini M 《Veterinary pathology》2003,40(6):693-694

Hepatic fibrosis with bile duct ectasia and hyperplasia associated with polycystic kidney disease, analogous to Caroli syndrome in humans, was observed in a rat used as a control in a subchronic toxicity study. Light microscopy of liver sections showed multiple cystic and segmental saccular dilatations and hyperplasia of the intrahepatic bile ducts associated with overgrowth of portal connective tissue; the kidneys had diffuse cystic dilatation of cortical renal tubules. The lesions resembled those of human cases of the fibropolycystic disease termed as Caroli syndrome, which is thought to be the result of a pathologic developmental process known as ductal plate malformation. Recently, an animal model of Caroli syndrome has been described in mutant rats from a colony that constantly showed renal and hepatic cysts and an autosomal recessive mode of inheritance. The finding in our case of identical hepatorenal lesions suggests that the same mutation has occurred incidentally in a standard colony.  相似文献   

Incidence of Poisonings in Domestic Carnivores in Italy     

Albo  A. Giuliano  Nebbia  C. 《Veterinary research communications》2004,28(1):83-88

Veterinary Research Communications -  相似文献   

Clinical and pathological findings of acute zinc intoxication in a puppy     

Gandini G  Bettini G  Pietra M  Mandrioli L  Carpenè E 《The Journal of small animal practice》2002,43(12):539-542

This report describes the clinical and pathological findings in a case of acute zinc poisoning in a young dog. The puppy suffered four days of progressively more severe vomiting and diarrhoea. Jaundice and pale mucous membranes, severe haematemesis and haemoglobinuria were other findings. Despite intensive therapy, the dog died a few hours after hospitalisation. Postmortem examination revealed a metallic foreign body in the stomach, catarrhal gastritis, hepatomegaly and enlarged, dark kidneys. Histology showed hepatic centrilobular vacuolar degeneration, haemoglobinuric nephrosis with early tubular necrosis, haemosiderosis and extramedullary haematopoiesis, as well as neuronal damage. The foreign body was mainly composed of zinc. Plasma zinc values were markedly raised (34.5 microg/ml; normal range 0.8 to 1.0 microg/ml). Pathophysiological mechanisms of zinc poisoning are discussed.  相似文献   

Effects of the radiometric properties of innovative biodegradable mulching materials on snapdragon cultivation     

Evelia Schettini  Giuliano Vox  Barbara De Lucia 《Scientia Horticulturae》2007

Research on the application of innovative biodegradable materials for substrate mulching in greenhouse floricultural cultivation was carried out in Southern Italy. A transparent biodegradable film and a transparent biodegradable spray coating were compared with a commercial transparent low density polyethylene film. The biodegradable film was a starch based extruded material, the sprayed coating was created from a polysaccharide solution. The materials were used to mulch the peat and perlite growing media contained in trays during snapdragon cultivation in order to increase the substrate temperature and hasten early growth. The climate variables inside and outside the greenhouse and the growing medium temperature under the mulching materials were recorded. Biometrical data, such as mean blooming time, plant height and spike length, were collected. The laboratory radiometric tests showed that the biodegradable mulching materials had a lower solar transmissivity in comparison to the low density polyethylene film. The capacity to reduce the long wave infrared thermal losses was higher for the biodegradable mulches: the long wave infrared transmissivity coefficient was 53.9% for the low density polyethylene film, 12.1% for the biodegradable film and 8.2% for the spray coating. The increase of the growing medium temperature allowed the harvest of the snapdragon grown in the mulched trays 7 days before that of the flowers grown in the un-mulched trays. At the end of the crop cycle the disposal of the biodegradable mulching materials was carried out fragmenting and mixing them with plant residue and the growing medium. The residue biodegraded in almost 1 month for the spray coating and in about 12 months for the biodegradable film.  相似文献   

Incidence of poisonings in domestic carnivores in Italy     

Giuliano Albo A  Nebbia C 《Veterinary research communications》2004,28(Z1):83-88

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Inferomedial placement of a single-entry subpalpebral lavage tube for treatment of equine eye disease     

Giuliano EA  Maggs DJ  Moore CP  Boland LA  Champagne ES  Galle LE 《Veterinary ophthalmology》2000,3(2-3):153-156

The objective of this study was to describe method of placement, and frequency and severity of complications associated with a subpalpebral lavage system placed in the medial aspect of the equine inferior eyelid. The inferomedial subpalpebral lavage (ISPL) tube is positioned deep in the medial aspect of the inferior conjunctival fornix so that the footplate lies flat between the lower eyelid and the anterior surface of the nictitans. Retrospective data from the placement of 92 ISPL systems placed in 86 horses during a 31-month period were examined. Tube placement was performed using sedation and regional anesthesia only in 59% of horses. The median duration of tube placement was 19 days (range: 1-61 days). Seventy-one horses were treated for up to 55 days following discharge from hospital with an ISPL tube in place. No complications were reported with 59% of ISPL systems. Non-ocular complications were found in 38% of ISPL systems and included tube displacement from the conjunctival fornix (18%), suture loss requiring resuturing of the system to the horse's head (14%), and damage necessitating replacement of the injection port (6%). Ocular complications were recorded in 3% of horses and were limited to inferior eyelid swelling. Vision was retained in 88% of horses. The ISPL system is easily and safely placed, and well tolerated for extended periods. It appears to be associated with infrequent and minor complications when compared with placement of subpalpebral lavage tubes in the superior eyelid.  相似文献   

Identification of a universal Group B streptococcus vaccine by multiple genome screen   总被引：2，自引：0，他引：2  

Maione D  Margarit I  Rinaudo CD  Masignani V  Mora M  Scarselli M  Tettelin H  Brettoni C  Iacobini ET  Rosini R  D'Agostino N  Miorin L  Buccato S  Mariani M  Galli G  Nogarotto R  Nardi-Dei V  Nardi Dei V  Vegni F  Fraser C  Mancuso G  Teti G  Madoff LC  Paoletti LC  Rappuoli R  Kasper DL  Telford JL  Grandi G 《Science (New York, N.Y.)》2005,309(5731):148-150

Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we analyzed the genome sequences of eight GBS isolates and cloned and tested 312 surface proteins as vaccines. Four proteins elicited protection in mice, and their combination proved highly protective against a large panel of strains, including all circulating serotypes. Protection also correlated with antigen accessibility on the bacterial surface and with the induction of opsonophagocytic antibodies. Multigenome analysis and screening described here represent a powerful strategy for identifying potential vaccine candidates against highly variable pathogens.  相似文献   

Ketamine‐dexmedetomidine combination and controlled mild hypothermia for the treatment of long‐lasting and super‐refractory status epilepticus in 3 dogs suffering from idiopathic epilepsy     

Daniela Gioeni  Federica Di Cesare  Elisa Silvia D'Urso  Vanessa Rabbogliatti  Giuliano Ravasio 《Journal of Veterinary Emergency and Critical Care》2020,30(4):455-460

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