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The counterdiffusion of gases across a composite layer can lead to supersaturation and development of bubbles within the layer. A physicochemical model has been derived to predict the extent of such supersaturation; experiments with inert liquid layers confirm predictions. These findings explain the evolution of cutaneous lesions observed in man during simulated deep-sea dives and the cutaneous lesions and intravascular bubbles experimentally induced in pigs by exchanging certain inert gases across the skin. The phenomena associated with counterdiffusion have widespread physical and biological implications. 相似文献
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Graves AH 《Science (New York, N.Y.)》1918,48(1252):652-653
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Graves HB 《Science (New York, N.Y.)》1973,182(4115):937-939
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Graves HS 《Science (New York, N.Y.)》1915,41(1047):117-127
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Marshall Graves JA 《Science (New York, N.Y.)》2003,300(5626):1621
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Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells 总被引:17,自引:0,他引:17
D T Graves A J Owen R K Barth P Tempst A Winoto L Fors L E Hood H N Antoniades 《Science (New York, N.Y.)》1984,226(4677):972-974
19.
Triiodothyronine (T3) suppression test. An aid in the diagnosis of mild hyperthyroidism in cats 总被引:2,自引:0,他引:2
M E Peterson T K Graves D A Gamble 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1990,4(5):233-238
The purpose of this study was to develop a T3 suppression test to help in the diagnosis of mild hyperthyroidism in cats. We evaluated the response in circulating T4 concentrations to exogenous T3 (liothyronine) administration in 44 clinically normal cats, 77 cats with hyperthyroidism, and 22 cats with nonthyroidal disease. The test was performed by first collecting blood samples for basal serum T4 and T3 determinations, administering liothyronine at an oral dosage of 25 micrograms three times daily for seven doses, and, on the morning of the third day, again collecting serum samples for T4 and T3 determinations 2 to 4 hours after the seventh dose of liothyronine. The mean basal serum concentrations of T4 (53.1 nmol/L) and T3 (1.8 nmol/L) were significantly higher in the cats with hyperthyroidism than in the normal cats (T4 = 25.3 nmol/L, T3 = 1.3 nmol/L) and the cats with nonthyroidal disease (T4 = 29.5 nmol/L, T3 = 1.4 nmol/L); however, there was a great deal of overlap of basal values between the three groups of cats. Of the 77 cats with mild hyperthyroidism, 41 (53%) had serum T4 values and 55 (71%) had T3 values that were within the established normal ranges. After administration of liothyronine, mean serum T4 concentrations fell much more markedly in the normal cats and the cats with nonthyroidal disease than in the hyperthyroid cats.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
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