A Bayesian Approach to Spatial Prediction With Flexible Variogram Models     

Stefano Castruccio  Luca Bonaventura  Laura M. Sangalli 《Journal of Agricultural, Biological & Environmental Statistics》2012,17(2):209-227

A Bayesian approach to covariance estimation and spatial prediction based on flexible variogram models is introduced. In particular, we consider black-box kriging models. These variogram models do not require restrictive assumptions on the functional shape of the variogram; furthermore, they can handle quite naturally non isotropic random fields. The proposed Bayesian approach does not require the computation of an empirical variogram estimator, thus avoiding the arbitrariness implied in the construction of the empirical variogram itself. Moreover, it provides a complete assessment of the uncertainty in the variogram estimation. The advantages of this approach are illustrated via simulation studies and by application to a well known benchmark dataset.  相似文献   

Zygomatic gland adenoma in a dog: histochemical and immunohistochemical evaluation     

Giudice C  Marco R  Mirko R  Luca M  Giorgio C 《Veterinary ophthalmology》2005,8(1):13-16

Orbital epithelial tumors in dogs are rare and most frequently malignant. Distinguishing their origin from the lacrimal or zygomatic gland is often challenging and is based mostly on tumor location. A case of adenoma involving the orbit in a 13-year-old, female, standard Schnauzer is reported. Histologically, the neoplasm was characterized by nests and cords of epithelial cells mostly forming small glandular structures. The origin of the tumor from the zygomatic gland was determined by histochemical characteristics (alcian blue pH 1 positive staining) of a small remnant of normal gland included within the tumor capsule. The benign nature of our finding was confirmed by follow-up information: 2 years after complete surgical removal of the mass no tumor recurrence or metastases was recorded.  相似文献   

Management and long-term outcome of partial glossectomy in 2 horses     

Hayley M. Lang  Luca Panizzi  Travis T. Smyth  Andrea E. Plaxton  Katharina L. Lohmann  Spencer M. Barber 《The Canadian veterinary journal. La revue veterinaire canadienne》2014,55(3):263-267

Records were reviewed for 2 horses with partial glossectomy, 1 traumatic and 1 elective. According to long-term follow-up by telephone, both horses had recovered well, experiencing only temporary difficulty while eating, and went on to be ridden successfully using mouth bits. Partial glossectomy, therefore, had a favorable prognosis in 2 performance horses.  相似文献   

Feline eosinophilic dermatoses: a retrospective immunohistochemical and ultrastructural study of extracellular matrix remodelling     

Ilaria Porcellato  Andrea Giontella  Luca Mechelli  Emilia Del Rossi  Chiara Brachelente 《Veterinary dermatology》2014,25(2):86-e26

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A human genome diversity cell line panel     

Cann HM  de Toma C  Cazes L  Legrand MF  Morel V  Piouffre L  Bodmer J  Bodmer WF  Bonne-Tamir B  Cambon-Thomsen A  Chen Z  Chu J  Carcassi C  Contu L  Du R  Excoffier L  Ferrara GB  Friedlaender JS  Groot H  Gurwitz D  Jenkins T  Herrera RJ  Huang X  Kidd J  Kidd KK  Langaney A  Lin AA  Mehdi SQ  Parham P  Piazza A  Pistillo MP  Qian Y  Shu Q  Xu J  Zhu S  Weber JL  Greely HT  Feldman MW  Thomas G  Dausset J  Cavalli-Sforza LL 《Science (New York, N.Y.)》2002,296(5566):261-262

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Development of a human adaptive immune system in cord blood cell-transplanted mice     

Traggiai E  Chicha L  Mazzucchelli L  Bronz L  Piffaretti JC  Lanzavecchia A  Manz MG 《Science (New York, N.Y.)》2004,304(5667):104-107

Because ethical restrictions limit in vivo studies of the human hemato-lymphoid system, substitute human to small animal xenotransplantation models have been employed. Existing models, however, sustain only limited development and maintenance of human lymphoid cells and rarely produce immune responses. Here we show that intrahepatic injection of CD34+ human cord blood cells into conditioned newborn Rag2-/-gammac-/- mice leads to de novo development of B, T, and dendritic cells; formation of structured primary and secondary lymphoid organs; and production of functional immune responses. This provides a valuable model to study development and function of the human adaptive immune system in vivo.  相似文献   

Intestinal calcium absorption: nature of defect in chronic renal disease   总被引：5，自引：0，他引：5  

L V Avioli  S Scott  S W Lee  H F De Luca 《Science (New York, N.Y.)》1969,166(909):1154-1156

When compared to that of normal animals, calcium-binding protein activity of duodenal mucosa obtained from uremic rats was decreased. There was no change in this activity after vitamin D(3), therapy. In contrast, prior treatment with 25-hydroxycholecalcijerol resulted in increased transport of calcium-45 and calcium-binding protein activity in the intestine.  相似文献   

The highland mangabey Lophocebus kipunji: a new species of African monkey     

Jones T  Ehardt CL  Butynski TM  Davenport TR  Mpunga NE  Machaga SJ  De Luca DW 《Science (New York, N.Y.)》2005,308(5725):1161-1164

A distinct species of mangabey was independently found at two sites 370 kilometers apart in southern Tanzania (Mount Rungwe and Livingstone in the Southern Highlands and Ndundulu in the Udzungwa Mountains). This new species is described here and given the name "highland mangabey" Lophocebus kipunji sp. nov. We place this monkey in Lophocebus, because it possesses noncontrasting black eyelids and is arboreal. L. kipunji is distinguished from other mangabeys by the color of its pelage; long, upright crest; off-white tail and ventrum; and loud call. This find has implications for primate evolution, African biogeography, and forest conservation.  相似文献   

A combined protocol with piroxicam,chemotherapy, and whole pelvic irradiation with simultaneous boost volumetric modulated arc radiotherapy for muscle-invasive canine urinary transitional cell carcinoma: First clinical experience     

Luca MALFASSI  Francesca FIDANZIO  Massimo SALA  Silvia MARCARINI  Giovanni MAZZA  Nancy CARRARA  Simone PAVESI  Giacomo GNUDI  Gaetano URSO  Mario DOLERA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(4):695

The aims of this pilot study were to evaluate the feasibility and efficacy of high-dose hypofractionated volumetric modulated arc radiotherapy (VMAT) applied to whole pelvic region radiotherapy (WPRT) with multilevel simultaneous integrated boost (MLSIB) combined with piroxicam and chemotherapy for the treatment of canine transitional cell carcinoma (TCC) of the lower urinary tract with muscle invasion TCC. Twelve dogs were enrolled, according to stage, in two groups: group 1, TCC confined to the urinary tract; group 2, TCC with metastasis. The planning target volume dose was tailored from 36 to 42 Gy in 6 fractions. All dogs were prescribed piroxicam and radiosensitizing carboplatin, and six received chemotherapy after radiotherapy. Serial follow-ups with computed tomography and magnetic resonance imaging were performed. Disease control and toxicity effects were evaluated according to the Response Evaluation Criteria in Solid Tumors and Veterinary Radiation Therapy Oncology Group criteria. The treatment was well tolerated, and no high-grade side effects were reported. The median overall survival times for groups 1 and 2 were 1,230 and 150 days, respectively. A considerable percentage of patients in group1 (50%) were still alive at the time of writing this paper, and a longer follow-up could enable a more accurate survival analysis. This preliminary analysis shows that VMAT applied to the WPRT with MLSIB is an effective and safe option for dogs with lower urinary TCC, although the presence of metastases worsens the prognosis.  相似文献   

Phenolic constituents and antioxidant activity of Wendita calysina leaves (Burrito), a folk Paraguayan tea     

Piccinelli AL  De Simone F  Passi S  Rastrelli L 《Journal of agricultural and food chemistry》2004,52(19):5863-5868

Burrito tea originates from the leaves of Wendita calysina, an indigenous Paraguayan plant, which is commonly consumed in South America and in Western countries. Phytochemical investigation of this species has led to the isolation of 14 constituents, among them 2 new flavanonols, dihydroquercetagetin (1) and 3,5,6,7,4'-pentahydroxyflavanonol (2), in addition to several known methoxyflavones, methoxyflavonols, phenylethanoid glycosides, and benzoic acid derivatives (4-14). All structures were elucidated by ESI-MS and NMR spectroscopic methods. Quantitative determination of phenolic constituents from burrito water infusions has been performed by HPLC-UV-DAD. The total antioxidant activity of the tea was measured by the ABTS(*)(+) radical cation decolorization and chemiluminescence (CL) assays and compared with the values of other commonly used herbal teas (green and black teas, mate, and rooibos).  相似文献