Encrusting cystitis in a cat secondary to Corynebacterium urealyticum infection     

Briscoe KA  Barrs VR  Lindsay S  Hoffmann KL  Cockwill KR  Muscatello G  Beatty JA 《Journal of Feline Medicine and Surgery》2010,12(12):972-977

An 18-year-old male neutered domestic shorthair cat was presented for investigation of haematuria and lethargy. The cat had sustained a traumatic T3-L3 lesion 5 years prior resulting in upper motor neuron incontinence. On further investigation the cat was found to be hyperkalaemic, hypothermic and dehydrated. Ultrasonography of the bladder revealed a markedly hypoechoic, thickened bladder wall with an irregular, hyperechoic mucosal layer. The patient responded to symptomatic and supportive care and was discharged. Despite initial improvement, the patient returned 10 days after discharge with recurrence of haematuria and lethargy. Ultrasound-guided aspiration and culture of the material on the mucosal surface of the bladder confirmed diagnosis of UTI caused by Corynebacterium urealyticum. On post-mortem examination, gross and histopathological features were consistent with encrusting cystitis. This is the first case report of encrusting cystitis in a cat. C urealyticum, an uncommon urinary tract pathogen in small animals, should be considered in patients with predisposing conditions.  相似文献   

Composition and evaluation of a novel web-based decision support system for grape black rot control     

Daniel Molitor  Barbara Augenstein  Laura Mugnai  Pietro Antonello Rinaldi  Jorge Sofia  Bryan Hed  Pierre-Henri Dubuis  Mauro Jermini  Erhard Kührer  Gottfried Bleyer  Lucien Hoffmann  Marco Beyer 《European journal of plant pathology / European Foundation for Plant Pathology》2016,144(4):785-798

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Penetrative and dislodgeable residue characteristics of 14C-insecticides in apple fruit     

Mota-Sanchez D  Cregg B  Hoffmann E  Flore J  Wise JC 《Journal of agricultural and food chemistry》2012,60(12):2958-2966

Infinite- and finite-dose laboratory experiments were used to study the penetrative and dislodgeable residue characteristics of (14)C-insecticides in apple fruit. The differences in dislodgeable and penetrated residues of three radiolabeled insecticides ((14)C-thiamethoxam, (14)C-thiacloprid, and (14)C-indoxacarb), applied in aqueous solution with commercial formulations, were determined after water and methanol wash extractions. The rate of sorption and extent of penetration into the fruit cuticles and hypanthium of two apple cultivars were measured after 1, 6, and 24 h of treatment exposure, using radioactivity quantification methods. For all three compounds, 97% or more of the treatment solutions were found on the fruit surface as some form of non-sorbed residues. For indoxacarb, sorption into the epicuticle was rapid but desorption into the fruit hypanthium was delayed, indicative of a lipophilic penetration pathway. For the neonicotinoids, initial cuticular penetration was slower but with no such delay in desorption into the hypanthium.  相似文献   

Methionine oxidation enhances κ-casein amyloid fibril formation     

Koudelka T  Dehle FC  Musgrave IF  Hoffmann P  Carver JA 《Journal of agricultural and food chemistry》2012,60(16):4144-4155

The effects of protein oxidation, for example of methionine residues, are linked to many diseases, including those of protein misfolding, such as Alzheimer's disease. Protein misfolding diseases are characterized by the accumulation of insoluble proteinaceous aggregates comprised mainly of amyloid fibrils. Amyloid-containing bodies known as corpora amylacea (CA) are also found in mammary secretory tissue, where their presence slows milk flow. The major milk protein κ-casein readily forms amyloid fibrils under physiological conditions. Milk exists in an extracellular oxidizing environment. Accordingly, the two methionine residues in κ-casein (Met(95) and Met(106)) were selectively oxidized and the effects on the fibril-forming propensity, cellular toxicity, chaperone ability, and structure of κ-casein were determined. Oxidation resulted in an increase in the rate of fibril formation and a greater level of cellular toxicity. β-Casein, which inhibits κ-casein fibril formation in vitro, was less effective at suppressing fibril formation of oxidized κ-casein. The ability of κ-casein to prevent the amorphous aggregation of target proteins was slightly enhanced upon methionine oxidation, which may arise from the protein's greater exposed surface hydrophobicity. No significant changes to κ-casein's intrinsically disordered structure occurred upon oxidation. The enhanced rate of fibril formation of oxidized κ-casein, coupled with the reduced chaperone ability of β-casein to prevent this aggregation, may affect casein-casein interaction within the casein micelle and thereby promote κ-casein aggregation and contribute to the formation of CA.  相似文献   

Salix rubens and Salix triandra Species as Phytoremediators of Soil Contaminated with Petroleum-Derived Hydrocarbons     

Ana Cristina Borba da Cunha  Sydney Sabedot  Carlos Hoffmann Sampaio  Claudete Gindri Ramos  Alexandre Rodrigues da Silva 《Water, air, and soil pollution》2012,223(8):4723-4731

The petroleum industry activities provide potential risks to the environment because they can contaminate ecosystems with different organic compounds in the production chain. Several accidents with transport and handling of petroleum and related products occurred in urban areas with harmful effects to the quality of life and economy. In the 1990s, bioremediation and phytoremediation technologies as economically feasible alternatives to repair the environmental damage were developed. In this study, the potential of the willows Salix rubens and Salix triandra were evaluated with regard to the phytoremediation of soils contaminated with petroleum-derived hydrocarbons (total hydrocarbons and polycyclic aromatic hydrocarbons (PAHs)). The PAHs were quantified by extraction from soils and plants using dichloromethane under ultrasonication. The HPLC analysis was performed with GC/MSD equipment. The total hydrocarbons present in uncontaminated soil were quantified by the sum of animal/vegetable oils and greases and mineral oils and greases according to Standard Methods 5520 (1997). The two willows species S. rubens and S. triandra were resistant during the project development. In the contaminated soil, in which both species were planted, the total hydrocarbons concentration was reduced near 98?%. The PAHs content was remarkably reduced as well. Pyrene showed an initial concentration of 23.06???g?kg^?1, decreasing in most cases to 0.1???g?kg^?1 or to undetectable levels. Chrysene decreased from 126.27???g?kg^?1 to undetectable levels. Benzo[k]fluoranthene and benzo[a]pyrene concentrations had also showed a decrease from 28.44 and 3.82???g?kg^?1, respectively, to undetectable levels.  相似文献   

Relationship between leaf apoplast pH and iron chlorosis of sunflower (Helianthus annuus L.)     

Konrad Mengel  Rudiger Planker  Bernd Hoffmann 《Journal of plant nutrition》2013,36(6):1053-1065

A hypothesis has been presented and tested that bicarbonate (HCO₃) and nitrate (NO₃) are the most important anions inducing iron (Fe) chlorosis because these anions increase the pH of leaf apoplast which in turn depresses ferric‐iron [Fe(III]) reduction, and hence, the uptake of Fe into the symplasm. Experiments with young sunflower (Helianthus annuus) plants showed that nutrition with NO₃ as the sole nitrogen (N) source induced chlorosis whereas ammonium nitrate (NH₄NO₃) did not. Monohydrogen carbonate (bicarbonate) also favoured the development of chlorosis. The degree of chlorosis was not related to the Fe concentration in the leaves. Both anion species, NO₃ and HCO₃, increased the pH of the leaf apoplast which was measured by means of the fluorescence dye 5‐carboxyfluorescein. A highly significant negative correlation between leaf apoplast pH and chlorophyll concentration in the leaves (r = ‐0.97) was found. Ferric‐Fe reduction in the apoplast—measured by means of ferrocene—provided evidence that a low leaf apoplast pH, obtained with ammonium (NH₄) supply, favoured the reduction of Fe(III) as compared with a higher leaf apoplast pH obtained with NO₃ supply. These results support the hypothesis tested.  相似文献   

Humus und Klimaänderung - Ergebnisse aus 15 langjährigen Dauerfeldversuchen     

Martin Körschens  Erhard Albert  Michael Baumecker  Frank Ellmer  Michael Grunert  Sandor Hoffmann 《Archives of Agronomy and Soil Science》2013,59(11):1485-1517

Zusammenfassung

Die Quantifizierung des Einflusses von Klimaänderungen auf den Humusgehalt des Bodens ist von großer wirtschaftlicher und wissenschaftlicher Bedeutung. Eine Möglichkeit dieser Quantifizierung besteht in der Auswertung von Dauerfeldversuchen mit der kontinuierlichen Bestimmung des Kohlenstoff- und Stickstoffgehaltes von Böden über einen Zeitraum von mehreren Jahrzehnten unter Wahrung des Ceteris-Paribus-Prinzips. Für die vorliegende Arbeit wurden die Ergebnisse von insgesamt 15 Dauerfeldversuchen an zehn verschiedenen Standorten mit rund 150 unterschiedlichen Düngungsvarianten ausgewertet. Die Versuchsdauer lag mit einer Ausnahme zwischen 40 und 110 Jahren. Die C_org-Daten konnten nahezu lückenlos über einen Zeitraum von jeweils 20 Jahren einbezogen werden. Die N_t-Gehalte wurden in sechs Versuchen berücksichtigt. Die Ergebnisse zeigen, dass bei allen Prüfgliedern mit kombinierter organisch-mineralischer Düngung in der Größenordnung, wie sie der “guten fachlichen Praxis“ oder auch der Humusbilanzmethode entspricht, keine Verringerung der C_org-Gehalte eingetreten ist. In einigen Fällen waren signifikante Erhöhungen zu verzeichnen. In 11 von 15 Versuchen war auch ohne Düngung oder mit ausschließlicher Mineraldüngung keine Reduzierung und somit keine klimabedingte Verringerung der Humusgehalte im Untersuchungszeitraum nachweisbar. Stattdessen wurde in einigen Fällen eine signifikante Erhöhung gefunden. Auch bei den N_t-Gehalten war in keinem Fall eine signifikante Verringerung festzustellen. Umfangreiche Großzahlanalysen und Dauerfeldversuchsauswertungen anderer Autoren bestätigen uneingeschränkt die Ergebnisse.  相似文献   

Die Auswertung langjähriger Reihen von Feldversuchs-erträgen in Verbindung mit agrarmeteorologischen Daten     

Erich Hoffmann  Erwin Bahn  Hannelore Dörfel 《Archives of Agronomy and Soil Science》2013,59(7):681-696

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Die Vermehrung der Baumweide (Salix albe)     

Rudolf Hoffmann 《Forstwissenschaftliches Centralblatt》1938,60(2):41-52

Ohne Zusammenfassung  相似文献   

Untersuchungen über die Keimung und das Jugendwachstum der Schwarz- und Walnuß     

Rudolf Hoffmann 《European Journal of Forest Research》1942,64(3-4):59-91

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