Detection of intra‐cardiac thrombi and congestive heart failure in cats using computed tomographic angiography          下载免费PDF全文

Kyle P. Vititoe  Ryan C. Fries  Stephen Joslyn  Laura E. Selmic  Mark Howes  Jordan P. Vitt  Robert T. O'Brien 《Veterinary radiology & ultrasound》2018,59(4):412-422

Arterial thromboembolism is a life‐threatening condition in cats most commonly secondary to cardiac disease. Echocardiography is the reference standard to evaluate for presence of a thrombus. In humans, computed tomographic (CT) angiography is becoming widely used to detect left atrial thrombi precluding the use of sedation. The purpose of this prospective, controlled, methods comparison pilot study was threefold: (1) describe new CT angiography protocol used in awake cats with cardiac disease and congestive heart failure; (2) determine accuracy of continuous and dynamic acquisition CT angiography to identify and characterize cardiac thrombi from spontaneous echocardiographic contrast using transthoracic echocardiography as our reference standard; (3) identify known negative prognostic factors and comorbidities of the thorax that CT angiography may provide that complement or supersede echocardiographic examination. Fourteen cats with heart disease were recruited; 7 with thrombi and 7 with spontaneous echocardiographic contrast. Echocardiography and awake CT angiography were performed using a microdose of contrast. Six of 7 thrombi were identified on CT angiography as filling defects by at least one reviewer within the left auricle (n = 6) and right heart (n = 1). Highest sensitivity (71.4%) was in continuous phase and highest specificity (85.7%) was in dynamic studies with fair to moderate interobserver agreement (0.38 and 0.44). CT angiography identified prognostic cardiac information (left atrial enlargement, congestive heart failure, arterial thromboembolism) and comorbidities (suspected idiopathic pulmonary fibrosis, asthma). This study indicates CT angiography can readily identify cardiac thrombi, important prognostic information and comorbidities, and can be safely performed in cats with cardiac disease and congestive heart failure.  相似文献   

ANGSTROM IN ENGLISH     

Fries EF 《Science (New York, N.Y.)》1928,67(1748):652-653

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Comparison of DDT effect on pentobarbital metabolism in rats and quail     

J Bitman  H C Cecil  S J Harris  G F Fries 《Journal of agricultural and food chemistry》1971,19(2):333-338

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In vitro and in vivo characterization of avian Escherichia coli. I. Serotypes, metabolic activity, and antibiotic sensitivity   总被引：4，自引：0，他引：4  

S S Cloud  J K Rosenberger  P A Fries  R A Wilson  E M Odor 《Avian diseases》1985,29(4):1084-1093

Over a 2 1/2-year period (January 1981 to June 1983), 177 Escherichia coli isolates were obtained from 145 field-reared broiler flocks in the Delmarva peninsula, and 20 were obtained from clinically normal day-old hatchery chickens representing an additional 17 flocks in Delmarva. Ninety-one isolates obtained from the field-reared birds between 2 and 8 weeks of age were associated with complicated air-sac disease. Serotyping efforts demonstrated a predominance of O2, O35, and O78 serogroups and a large number of untypable isolates. More than 50% of the isolates in each of the three dominant serogroups were collected from broilers with colibacillosis, but they were never detected in the yolk-sac samples of clinically normal day-old hatchery chickens. In vitro biochemical characterization of the E. coli isolates revealed variable rates of carbohydrate fermentation and amino acid decarboxylation. No common characteristics appeared to be shared by the predominant serogroups isolated from clinically affected birds, although several serogroup-specific reactions were noted. The majority of the isolates were sensitive to chloramphenicol, gentamicin, nalidixic acid, ormethoprim-sulfadimethoxine, spectinomycin, neomycin, and ampicillin. About half of the isolates were sensitive to nitrofurantoin and the sulfa compounds. Less than 25% of the isolates were sensitive to streptomycin, erythromycin, tetracyclines, novobiocin, penicillin, bacitracin, and lincomycin.  相似文献   

Inherited myopathy in a litter of Labrador retrievers.   总被引：4，自引：1，他引：3       下载免费PDF全文

K Gortel  D M Houston  T Kuiken  C L Fries    B Boisvert 《The Canadian veterinary journal. La revue veterinaire canadienne》1996,37(2):108-110

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Statistical evaluation of repeated samples for total pathogen count determination on surfaces     

G Janke-Grimm  R Fries 《DTW. Deutsche tier?rztliche Wochenschrift》1985,92(2):49-54

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Prevalence of the myosin-binding protein C mutation in Maine Coon cats     

Fries R  Heaney AM  Meurs KM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2008,22(4):893-896

BACKGROUND: An autosomal dominant mutation has been identified in the myosin-binding protein C (MYBPC3) gene of Maine Coon cats. This mutation changes a conserved amino acid and computationally alters the protein conformation of this gene in Maine Coon cats with hypertrophic cardiomyopathy. The prevalence of this mutation is unknown. OBJECTIVE: To determine the genetic prevalence of the MYBPC3 mutation in a large cohort of predominantly Maine Coon cats. ANIMALS: Three thousand three hundred and ten DNA samples (blood or buccal swab) from cats. METHODS: This retrospective study reviewed the Veterinary Cardiac Genetics Laboratory database at Washington State University for samples submitted for evaluation of the Maine Coon MYBPC3 mutation. The data were analyzed with respect to the breed of cat, mutation status (negative, heterozygous, homozygous), and geographic origin of the submission. RESULTS: In the population of cats studied, Maine Coon cats accounted for 100% of all cats positive for the mutation, and the worldwide percentage of Maine Coon cats carrying the MYBPC3 mutation was 34%. CONCLUSIONS AND CLINICAL IMPORTANCE: The prevalence of the mutation (heterozygous or homozygous) was very similar among countries of submission, suggesting that the 34% mutation rate of the tested samples is a reasonable estimate of the true prevalence of the mutation within the breed. Because of the high prevalence of this mutation, a breeding recommendation to eliminate all cats with the mutation could have a substantial impact on the gene pool. Additional studies are indicated to explore the relationship between genotype and clinical outcome in affected cats.  相似文献   

Retention of sterically and electrosterically stabilized silver nanoparticles by soil minerals          下载免费PDF全文

M. Hoppe  R. Mikutta  S. Kaufhold  J. Utermann  W. Duijnisveld  E. Wargenau  E. Fries  G. Guggenberger 《European Journal of Soil Science》2016,67(5):573-582

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The perception of veterinary medicine in the print media     

Dünnebier K  Fries R 《DTW. Deutsche tier?rztliche Wochenschrift》2005,112(1):24-27

Between January 2000 and October 2003, a print media data bank on published contributions was screened for the German key words "Tierarzt/Tier?rztin" and "Veterin?r/Veterin?rin" (veterinary surgeon) and related items. 267 articles have been found. Regarding the contents, the articles were characterised according to the content (VPH, surgeons, other), and the cause of the article. Regarding the surgeon part, mostly companion animals are dealt with. If it comes to VPH, primarily so called scandals such as misuse of therapeuticals or epidemics (BSE, FMD) have been reported. In the first instance these articles reflect only a temporary interest, and they do not give real insight into the daily work of the profession. As a consequence, public intelligence on veterinary medicine may be misled by such press articles, possibly generating wrong expectations in young people who might start with veterinary medicine. Institutional bodies should provide information, which covers the subject in a more realistic way in order to prevent a wrong understanding of the profession and to offer the whole scope of the public functions of veterinary medicine.  相似文献   

Bacteriologic status of the muscle tissue of broilers in the fattening phase and following meat removal     

R Fries  R Tschischkale 《Berliner und Münchener tier?rztliche Wochenschrift》1987,100(7):233-237

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