Effect of dietary n-6-to-n-3 fatty acid ratio on complete blood and total white blood cell counts, and T-cell subpopulations in aged dogs     

Hall JA  Wander RC  Gradin JL  Du SH  Jewell DE 《American journal of veterinary research》1999,60(3):319-327

OBJECTIVE: To determine effect of diets with variable n-6-to-n-3 fatty acid (FA) ratio on CD4+ and CD8+ T-lymphocyte subpopulations, and on results of routine laboratory analyses (CBC and total WBC count, serum biochemical analyses, and urinalysis). ANIMALS: 20 healthy, aged (9.5 to 11.5 years old) female Beagles. PROCEDURE: Dogs were fed 1 of 3 diets that contained 6% fat by weight but differed in amounts of n-6 and n-3 FA. For 11 weeks, 6 dogs were fed a low concentration of n-3 FA (ratio, 31:1), 7 were fed a medium concentration (5.4:1), and 7 were fed a high concentration (1.4:1). Preprandial blood and urine samples were collected before beginning the study and at 8 weeks for evaluation of laboratory variables. Before and at 3, 6, and 8 weeks during the study, blood was drawn for total WBC and lymphocyte counts and for characterization of T-cell subpopulations. At 8 and 10 weeks, dogs were vaccinated with keyhole limpet hemocyanin suspension. Blood was drawn 4 days after each vaccination, and lymphocytes were isolated for flow cytometry. Effects of diet and vaccination on each variable were determined. RESULTS: After vaccination, total lymphocyte count increased and CD4+ T lymphocyte count and the CD4(+)-to-CD8+ ratio decreased in dogs consuming the diet with n-6-to-n-3 FA ratio of 1.4:1. CONCLUSION: Feeding a diet with n-6-to-n-3 FA ratio of 1.4:1 had significant effects on CD4+ T lymphocytes in healthy, aged Beagles after vaccination.  相似文献   

Effects of dietary change and rotavirus infection on small intestinal structure and function in gnotobiotic piglets   总被引：1，自引：0，他引：1  

G A Hall  K R Parsons  G L Waxler  K J Bunch  R M Batt 《Research in veterinary science》1989,47(2):219-224

The combined effects of weaning and rotavirus infection on small intestinal structure and function and on growth rate were studied in 28 gnotobiotic piglets. There was little damage by rotavirus to the proximal small intestine, some damage to the mid small intestine and relatively severe damage to the distal small intestine; villi were stunted, crypts lengthened and activities of all brush border enzymes decreased. The damage was short-lived despite the synchronisation of rotavirus infection with simulated weaning. There was no evidence of persistent damage to the small intestine and growth rate was unaffected.  相似文献   

Pathologic features of abdominal and thoracic paragangliomas in F344/N rats     

L B Hall  K Yoshitomi  G A Boorman 《Veterinary pathology》1987,24(4):315-322

Seventeen paragangliomas were identified in a retrospective review of 200 NTP/NCI carcinogenicity studies in F344/N rats that served either as control or treated animals. Most tumors were grossly visible and located in the retroperitoneum adjacent to the vertebrae and aorta near the kidneys. Three microscopically detected paragangliomas were found at the base of the heart. Microscopically, neoplastic cells were in nests separated by reticulin fibers and capillaries. Argyrophil granules were in the cytoplasm of the retroperitoneal and mediastinal paravertebral tumors. Dense granules were found in the one tumor examined ultrastructurally. Some tumors had areas of necrosis and tumor emboli were present in the lumen of the abdominal aorta and vena cava adjacent to the tumor with metastases present in pulmonary vessels. The incidence of retroperitoneal neoplasms was 3 times more frequent in male than in female F344/N rats.  相似文献   

The physiology of growth hormone in poultry     

C. G. Scanes  T. R. Hall  S. Harvey 《Domestic animal endocrinology》1984,1(3):201-215

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Haemophilus somnus infection in the cow as a possible contributing factor to weak calf syndrome: isolation and animal inoculation studies   总被引：8，自引：0，他引：8  

D G Waldhalm  R F Hall  W A Meinershagen  C S Card  F W Frank 《American journal of veterinary research》1974,35(11):1401-1403

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Effects of season and grass tetany on mineral composition of Hereford cattle hair     

R F Hall  W L Sanders  M C Bell  R A Reynolds 《American journal of veterinary research》1971,32(10):1613-1619

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Some Parameters of Cell Proliferation in a Solid Tumor1     

Ellis Hall 《Veterinary radiology & ultrasound》1968,9(1):99-108

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Anesthesia for cardiac surgery in calves   总被引：2，自引：0，他引：2  

C E Short  A S Keats  D Liotta  C W Hall 《American journal of veterinary research》1968,29(12):2287-2294

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John Gamgee and the Edinburgh new veterinary college     

S A Hall 《The Veterinary record》1965,77(42):1237-1241

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The effect of pseudorabies (Aujeszky''s) virus infection on young mature boars and boar fertility.   总被引：1，自引：0，他引：1       下载免费PDF全文

L B Hall  Jr  J P Kluge  L E Evans    H T Hill 《Canadian journal of veterinary research》1984,48(2):192-197

This study was designed to determine the effects of experimental inoculation with pseudorabies virus on the reproductive tracts of young adult boars. Pseudorabies virus was inoculated intranasally into 12 boars and intrapreputially into four boars. All animals seroconverted after nasal or preputial inoculation. Semen abnormalities were observed 21 days postinoculation with partial recovery by 50 days postinoculation. Virus was isolated from the preputial sheath of two intrapreputially inoculated boars 12 days postinoculation. It was concluded that pseudorabies virus infection can be established via preputial inoculation and that decreased spermatogenesis and infertility can result.  相似文献