Serial electroencephalographic studies of experimentally induced transmissible mink encephalopathy   总被引：1，自引：0，他引：1  

J D Grabow  R J Eckroade  R P Hanson 《American journal of veterinary research》1971,32(3):457-464

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Effects of tolazoline and yohimbine on xylazine-induced central nervous system depression, bradycardia, and tachypnea in sheep   总被引：2，自引：0，他引：2  

W H Hsu  D D Schaffer  C E Hanson 《Journal of the American Veterinary Medical Association》1987,190(4):423-426

We compared the ability of tolazoline and yohimbine to antagonize xylazine-induced central nervous system depression, bradycardia, and tachypnea in 9 ewes and 5 rams. Once a week for 3 weeks, each sheep received one IV treatment of 0.4 mg xylazine/kg, 0.4 mg xylazine/kg followed in 10 minutes by 2 mg tolazoline/kg, or 0.4 mg xylazine/kg followed in 10 minutes by 0.2 mg yohimbine/kg. The order of the 3 treatments in each sheep was randomized. Xylazine alone caused recumbency for 41.0 +/- 3.7 minutes (mean +/- SEM). Tolazoline and yohimbine shortened the xylazine-induced recumbency to 12.1 +/- 0.9 minutes and 18.1 +/- 1.5 minutes, respectively. Sheep given xylazine alone had head droop for 34.0 +/- 5.4 minutes after rising. Head drooping of sheep given tolazoline or yohimbine was reduced to 10.1 +/- 1.7 minutes and 14.2 +/- 1.7 minutes, respectively. Both tolazoline and yohimbine reversed the bradycardia and tachypnea that followed xylazine administration. No statistical differences in the rate and magnitude of the reversal were observed between the 2 drugs.  相似文献   

Experimental visceral leishmaniasis in the opossum     

M R White  W L Chapman  W L Hanson  K S Latimer  C E Greene 《Veterinary pathology》1989,26(4):314-321

Adult wild-trapped opossums were infected with Leishmania donovani (Khartoum strain, WR 378) and evaluated as an animal model of visceral leishmaniasis. All infected opossums died within 32 days. Loss of body fat, hepatomegaly, and petechiae of skin and abdominal musculature were seen at necropsy. Microscopically, numerous amastigote-laden macrophages were seen in histologic sections of liver, spleen, and lymph nodes; fewer parasite-laden macrophages were in the bronchial-associated lymphoid tissues and renal glomeruli. Hematological findings included thrombocytopenia (terminal), neutropenia, and lymphopenia. Blood lymphocyte blastogenesis in response to concanavalin A and phytohemagglutinin was decreased markedly at day 24 post-infection (PI). Serum antibodies (1:40 dilution) to promastigotes of L. donovani were detected in five of eight infected opossums tested on days 10 and 24 PI. Total bilirubin concentrations and alanine aminotransferase and aspartate aminotransferase activities were increased after day 25 PI. Activated partial thromboplastin times and one-stage prothrombin times were prolonged before death. Concurrently, factors V, VIII, and XII activities were decreased.  相似文献   

Identification and control of paratuberculosis in a large goat herd   总被引：1，自引：0，他引：1  

H M Gezon  H D Bither  H C Gibbs  E J Acker  L A Hanson  J K Thompson  R D Jorgenson 《American journal of veterinary research》1988,49(11):1817-1823

Mycobacterium paratuberculosis infection was detected in 2 goats in 1974 and in 5 goats in 1975; 5 of which were from a single herd. The magnitude of the subsequent epizootic in the goat herd was not recognized until 1977, when results of bacteriologic culture of fecal and tissue specimens, antibody determinations (agar-gel immuno-diffusion test), and histopathologic studies became available. By 1984, paratuberculosis had been diagnosed in 124 goats. Nearly all the goats were being used in antiserum production and had been given Freund complete adjuvant and human antigens. From 1974 to 1986, herd size varied from 100 to 300. The yearly incidence of paratuberculosis decreased from 13.2% (27 of 204 goats) in 1977 to 0% in 108 goats in 1985. The prevalence was higher in does. In goats that arrived on the farm in 1975 and before, 49 of 121 (40.5%) does developed paratuberculosis vs 41 of 120 (34.2%) wethers. In goats arriving on the farm in 1976 and after, 25 of 274 (8.5%) does and 9 of 216 (4.1%) wethers developed paratuberculosis. The average incubation period was approximately 4 years from arrival on the farm in every year except 1978, regardless of whether the goat was born on the farm or was purchased elsewhere.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Comparison of staple and suture techniques for end-to-end anastomosis of the small colon in horses     

R R Hanson  A J Nixon  M Calderwood-Mays  R Gronwall  J F Pendergast 《American journal of veterinary research》1988,49(9):1621-1628

Two techniques for end-to-end anastomosis of the small colon were evaluated in each of 6 horses. A simple interrupted suture pattern that excluded the mucosa and was oversewn with an inverting suture was compared with a triangulated double-row pattern of stainless steel staples. Anastomotic sites were evaluated at 2 weeks, 2 months, and 6 months for extent of abdominal adhesions, lumen diameter at anastomotic sites, bursting pressures, and healing response. Clinical postoperative complications were not associated with either technique. At postmortem examination, there was extensive adhesion formation from the mesocolon to the stapled anastomotic site. The suture technique resulted in greater luminal diameters (P less than or equal to 0.05), with good apposition of the tissue layers. Staples were missing as early as 2 weeks after surgery, and their loss was associated with separation of the muscularis at later evaluation periods. Regardless of technique, all but one anastomotic segment burst away from the anastomotic site along the mesenteric taenial band. For the 12 anastomoses performed in normal horses, the suturing technique was better than the stapling technique because of significantly larger lumen diameters, better anastomotic healing, and minimal intra-abdominal adhesion formation.  相似文献   

Reevaluation of the isoleucine requirement of the young pig     

G A Oestemer  L E Hanson  R J Meade 《Journal of animal science》1973,36(4):679-683

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IMMUNOGENICITY OF AUSTRALIAN LENTOGENIC STRAINS OF NEWCASTLE DISEASE VIRUS     

A. J. Turner  M.V.Sc.  Ph.D.  J. Spalatin  V.M.D R. P. Hanson  Ph.D.† 《Australian veterinary journal》1977,53(1):32-35

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Agents of Psittacosis-Lymphogranuloma Venereum Group Isolated from Muskrats and Snowshoe Hares in Saskatchewan   总被引：2，自引：0，他引：2       下载免费PDF全文

J. Spalatin  C. E. O. Fraser  R. Connell  R. P. Hanson    D. T. Berman 《Canadian journal of veterinary research》1966,30(9):260-264

Agents lethal to chicken embryos and mice were isolated from the blood and spleen of 2 muskrats and 2 snowshoe hares which died during the cataclysmic die-off of 1961 in Central Saskatchewan. The 4 isolates are probably identical. One of them was identified as a member of the psittacosis-lymphogranuloma venereum (PLV) group of organisms on the basis of morphological and tinctorial properties and on the possession of group specific antigens. Application of the method of specificity differences permitted its serotype differentiation.  相似文献   

SIMULATED NATURAL INFECTION OF CHICKENS WITH AUSTRALIAN LENTOGENIC NEWCASTLE DISEASE VIRUS AND SUBSEQUENT CHALLENGE WITH VIRULENT VIRUS   总被引：1，自引：0，他引：1  

A. J. Turner M.V.Sc.  Ph.D.    R. P. Hanson Ph.D.  J. Spalatin V.M.D. 《Australian veterinary journal》1976,52(11):524-528

A total of 291 eight-week-old chickens were exposed to chickens infected with either of two Australian lentogenic strains (V4 and AVL NDV-1) of Newcastle disease virus (NDV). At 3 weeks after exposure, all chickens exposed to V4 infected chickens had developed haemagglutination-inhibition (HI) antibody. All chickens exposed to AVL NDV-1 virus infected chickens had developed HI antibody 5 weeks later. This sudden late appearance of HI antibody, to titres higher than those observed with V4 chickens, was explained by V4 virus being introduced to the AVL NDV-1 group of chickens. When groups of these chickens were challenged with Roakin virus (mesogenic NDV) at 3 weeks and Fontana 1083 virus (viscerotropic velogenic NDV) and Texas GB virus (neutrotropic NDV) at 3, 5, 10 and 21 weeks only three chickens developed clinical illness one of which died. These chickens were one AVL NDV-1 chicken contact challenged with Fontana 1083 virus at 3 weeks, one V4 chicken oronasally challenged with Texas GB virus at 5 weeks and one V4 chicken challenged oronasally with Fontana 1083 virus at 10 weeks. Susceptible non-vaccinated chickens died soon after challenge. Challenge by oronasal infection with 10(7.0) ELD50 of virus or contact with susceptible infected chickens enabled virulent virus to be isolated from most chickens and was accompanied by a large anamnestic increase in serum HI antibody.  相似文献   

Treatment of parasitic ascites in a dog.     

J H Greve  R L Hanson  L D McGill 《Journal of the American Veterinary Medical Association》1979,174(8):828-829

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