International security. Energy security for North Korea     

Von Hippel D  Hayes P 《Science (New York, N.Y.)》2007,316(5829):1288-1289

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RIVER-BANK MOVEMENTS DUE TO THE EARTH'S ROTATION     

Hayes E 《Science (New York, N.Y.)》1922,55(1430):567-568

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Isolation of St. Louis encephalitis virus from overwintering Culex pipiens mosquitoes   总被引：3，自引：0，他引：3  

C L Bailey  B F Eldridge  D E Hayes  D M Watts  R F Tammariello  J M Dalrymple 《Science (New York, N.Y.)》1978,199(4335):1346-1349

Two strains of St. Louis encephalitis virus were isolated from overwintering mosquitoes collected in Maryland and Pennsylvania during January and February 1977. There isolations from Culex pipiens constitute evidence that a mosquito-borne flavivirus can persist in a vector mosquito in temperate climates during the winter season.  相似文献   

Relapse to cocaine-seeking after hippocampal theta burst stimulation     

Vorel SR  Liu X  Hayes RJ  Spector JA  Gardner EL 《Science (New York, N.Y.)》2001,292(5519):1175-1178

Treatment efforts for cocaine addiction are hampered by high relapse rates. To map brain areas underlying relapse, we used electrical brain stimulation and intracranial injection of pharmacological compounds after extinction of cocaine self-administration behavior in rats. Electrical stimulation of the hippocampus containing glutamatergic fibers, but not the medial forebrain bundle containing dopaminergic fibers, elicited cocaine-seeking behavior dependent on glutamate in the ventral tegmental area. This suggests a role for glutamatergic neurotransmission in relapse to cocaine abuse. The medial forebrain bundle electrodes supported intense electrical self-stimulation. These findings suggest a dissociation of neural systems subserving positive reinforcement (self-stimulation) and incentive motivation (relapse).  相似文献   

Ronidazole pharmacokinetics after intravenous and oral immediate-release capsule administration in healthy cats     

LeVine DN  Papich MG  Gookin JL  Davidson GS  Davis JL  Hayes RB 《Journal of Feline Medicine and Surgery》2011,13(4):244-250

Ronidazole (RDZ) is an effective treatment for feline Tritrichomonas foetus infection, but has produced neurotoxicity in some cats. An understanding of the disposition of RDZ in cats is needed in order to make precise dosing recommendations. Single-dose pharmacokinetics of intravenous (IV) RDZ and immediate-release RDZ capsules were evaluated. A single dose of IV RDZ (mean 9.2mg/kg) and a 95mg immediate-release RDZ capsule (mean 28.2mg/kg) were administered to six healthy cats in a randomized crossover design. Plasma samples were collected for 48 h and assayed for RDZ using high pressure liquid chromatography (HPLC). Systemic absorption of oral RDZ was rapid and complete, with detection in the plasma of all cats by 10 min after dosing and a bioavailability of 99.64 (±16.54)%. The clearance of RDZ following IV administration was 0.82 (±0.07) ml/kg/min. The terminal half-life was 9.80 (±0.35) and 10.50 (±0.82) h after IV and oral administration, respectively, with drug detectable in all cats 48h after both administrations. The high oral bioavailability of RDZ and slow elimination may predispose cats to neurotoxicity with twice-daily administration. Less frequent administration should be considered for further study of effective treatment of T foetus-infected cats.  相似文献   

Compartmentalization of mercury in biotic components of terrestrial flood plain ecosystems adjacent to the South River AT Waynesboro,VA     

Cocking  Dean  Hayes  Robert  King  Mary Lou  Rohrer  Mary Jane  Thomas  Ronald  Ward  Deanna 《Water, air, and soil pollution》1991,57(1):159-170

Water, Air, & Soil Pollution - Aquatic Hg contamination extending more than 200 km along the South River, South Fork of the Shenandoah River, and Shenandoah River in western VA has been...  相似文献   

Bovine papillomavirus type 4 in Australia     

N. BLOCH  RH SUTTON  M. BREEN  PB SPRADBROW 《Australian veterinary journal》1995,72(7):273-274

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Thiamin deficiency in cats and dogs associated with feeding meat preserved with sulphur dioxide     

VP STUDDERT  RH LABUC 《Australian veterinary journal》1991,68(2):54-57

Thiamin deficiency was diagnosed in cats and dogs being fed fresh minced meat, which contained sulphur dioxide as a preservative and less than 0.5 mg/kg thiamin. Thiamin in the meat and in added dietary ingredients, including a supplementary vitamin mixture, was destroyed by the sulphur dioxide.  相似文献   

Nutritional Problems in Cats: Taurine Deficiency and Vitamin A Excess   总被引：2，自引：0，他引：2       下载免费PDF全文

K. C. Hayes 《The Canadian veterinary journal. La revue veterinaire canadienne》1982,23(1):2-5

Two nutritional problems of the cat are reviewed. One represents a deficiency of taurine, the other vitamin A toxicity. Taurine deficiency in cats is insidious because the progressive retinal degeneration induced may go unnoticed until the damage is advanced and irreversible. Both rods and cones undergo degeneration along with the underlying tapetum lucidum. The hyperreflective focal lesion is easily observed in the area centralis with an ophthalmoscope and has been previously identified as feline central retinal degeneration. This lesion is not reversed by taurine supplementation, even though the remaining retina may be saved from further degeneration. The cat requires dietary taurine, found in meat and fish, because it cannot synthesize enough to meet demands for bile acid conjugation and tissue metabolism, especially those of muscle and central nervous system.

Vitamin A toxicity is not commonly observed in cats but may occur if cats are fed beef liver in which appreciable vitamin A is stored. Cats exhibit muscle soreness and hyperesthesia, especially along the neck and forelimbs where bony exostoses of cervical verterbrae and longbones are common. The diagnosis is readily made from radiographs. The response to removal of vitamin A from the diet is generally rapid and, unless the toxicity has been chronic in young kittens, recovery is generally satisfactory.

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Electrophoretic distribution and serologic changes of blood serum of arthritic (rheumatoid) white-tailed deer (Odocoileus virginianus) infected with Erysipelothrix insidiosa     

D Sikes  T P Kistner  J H Eve  F A Hayes 《American journal of veterinary research》1972,33(12):2545-2549

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