Comparison of Growth Factor Treatments on the Fibrochondrogenic Potential of Canine Fibroblast‐Like Synoviocytes for Meniscal Tissue Engineering     

Jason Spina DVM  Jennifer Warnock DVM  PhD  Diplomate ACVS‐SA  Wendy Baltzer DVM  PhD  Diplomate ACVS & ACVSMR  Jesse Ott BS  Brian Bay MS  PhD 《Veterinary surgery : VS》2014,43(6):750-760

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Concurrent Diseases and Conditions in Cats with Renal Infarcts     

M.C. Hickey  K. Jandrey  K.S. Farrell  D. Carlson‐Bremer 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2014,28(2):319-323

Background

Renal infarcts identified without definitive association with any specific disease process.

Objective

Determine diseases associated with diagnosis of renal infarcts in cats diagnosed by sonography or necropsy.

Animals

600 cats underwent abdominal ultrasonography, necropsy, or both at a veterinary medical teaching hospital.

Methods

Information obtained from electronic medical records. Cats classified as having renal infarct present based on results of sonographic evaluation or necropsy. Time‐matched case‐controls selected from cats that underwent the next scheduled diagnostic procedure.

Results

309 of 600 cats having diagnosis of renal infarct and 291 time‐matched controls. Cats 7–14 years old were 1.6 times (odds ratio, 95% CI: 1.03–2.05, P = .03) more likely to have renal infarct than younger cats but no more likely to have renal infarct than older cats (1.4, 0.89–2.25, P = .14). All P = .14 are statistically significant. Cats with renal infarcts were 4.5 times (odds ratio, 95% CI: 2.63–7.68, P < .001) more likely to have HCM compared to cats without renal infarcts. Cats with renal infarcts were 0.7 times (odds ratio, 95% CI: 0.51–0.99, P = .046) less likely to have diagnosis of neoplasia compared to cats without renal infarcts. Cats with diagnosis of hyperthyroidism did not have significant association with having renal infarct. Cats with renal infarcts were 8 times (odds ratio, 95% CI: 2.55–25.40, P ≤ .001) more likely to have diagnosis of distal aortic thromboembolism than cats without renal infarcts.

Conclusions and Clinical Importance

Cats with renal infarcts identified on antemortem examination should be screened for occult cardiomyopathy.  相似文献   

Detection of the Matrix Metalloproteinases MMP‐2 and MMP‐9 and Tissue Inhibitors of Metalloproteinases TIMP‐1 and TIMP‐2 in Llama (Lama glama) Oviduct     

R Zampini  ME Argañaraz  DC Miceli  SA Apichela 《Reproduction in domestic animals》2014,49(3):492-498

Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are involved in several reproductive events like oocyte–spermatozoa interaction and semen liquefaction. In order to study their role in the llama oviductal reproductive process, MMP activity in oviductal fluid (OF) was assayed. Considering that llama genome sequences are partially known, a strategy to procure cDNA sequences of MMP‐2, MMP‐9, TIMP‐1 and TIMP‐2 was designed. Afterwards, their expression patterns in the different llama oviductal segments were assayed. Gelatine zymograms detected 62 and 94 kDa protease activities that matched MMP‐2 and pro‐MMP‐9, respectively. Expression pattern analysis showed that MMP and TIMP mRNAs were present in ampulla, isthmus, utero‐tubal junction (UTJ) and papilla. Altogether, these findings support the argument that MMPs/TIMPs are produced in the oviduct and secreted into the oviductal lumen. Our results encourage further studies to elucidate the role of these proteins in reproductive oviductal events.  相似文献   

葡萄糖氧化酶和酵母硒复合添加剂对肉鸡生长性能、抗氧化性能及肉品质的影响   总被引：1，自引：0，他引：1  

孙春阳  邢焕  栾素军  萨仁娜  张宏福  丁美芳 《动物营养学报》2014,26(9)

本文旨在研究以葡萄糖氧化酶和酵母硒为主要成分的复合添加剂对规模化养殖白羽肉鸡生长性能、抗氧化性能和肉品质的影响.选择6 000只1日龄健康爱拔益加(AA)肉仔鸡,随机分为2个组,每组设4个重复,每个重复750只鸡.对照组饲喂玉米-豆粕基础饲粮,试验组饲喂基础饲粮+0.2％复合添加剂(葡萄糖氧化酶+酵母硒).试验期为42 d.结果表明:1)在不同日龄阶段(1 ～21、22～42、1～ 42日龄),试验组肉鸡平均日增重(ADG)、平均日采食量(ADFI)均显著高于对照组(P＜0.05),ADG分别提高了1.92％、1.42％、1.53％,ADFI分别提高了3.35％、6.64％、5.58％;试验组料重比(F/G)显著低于对照组(P＜0.05),分别降低了0.70％、4.46％、3.85％.1～42日龄试验组肉鸡死淘率显著低于对照组32.41％(P＜0.05).21、42日龄试验组肉鸡盲肠食糜pH显著低于对照组(P＜0.05).2)21日龄,试验组肉鸡血清超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性和总抗氧化能力(T-AOC)比对照组分别显著提高了2.01％、8.90％、8.89％ (P＜0.05).42日龄,试验组肉鸡SOD、GSH-Px活性和T-AOC比对照组分别显著提高了7.96％、13.23％和19.01％ (P＜0.05),丙二醛(MDA)含量比对照组显著降低34.93％ (P＜0.05).3)21、42日龄,试验组肉鸡胸肌肉色a值显著高于对照组(P＜0.05),肉色b值显著低于对照组(P＜0.05).综上,饲喂添加葡萄糖氧化酶和酵母硒的复合添加剂的饲粮可提高肉鸡生长性能、抗氧化性能,改善肉品质.  相似文献   

Distribution of As, Cd, Pb, and Zn in redox features of mine-waste impacted wetland soils   总被引：1，自引：0，他引：1  

Daniel G. Strawn  Patrick J. Hickey  Paul A. McDaniel  Leslie L. Baker 《Journal of Soils and Sediments》2012,12(7):1100-1110

Purpose

Wetland soils of the Coeur d??Alene (CdA) River Basin of northern Idaho, USA are contaminated with toxic elements released during mining activities. In this paper, we report results from a multi-scale investigation of total As, Cd, Pb, and Zn distributions along a transect of these contaminated soils.

Materials and methods

Four sites along an 80-m transect were established at the Black Rock Slough wetland in CdA River Basin. The elevation difference between the upslope and lowland site was 1.1?m. Soils were sampled from three depths, down to 45?cm. Redoximorphic features were isolated from the soils and categorized into five types of cemented particles, and Fe-enriched and depleted soil masses. Soils and isolated soil separates were analyzed for total elemental concentration.

Results and discussion

Within soil profiles, contaminants are enriched in surface horizons as compared to the original depositional profiles. Enrichment was more dramatic in the upland sites than the lowland sites. Fe-enriched masses that ranged in size from a few millimeters to several centimeters were also enriched in As, Pb, and Zn. At the smallest scale investigated, five different soil aggregate types ranging in size from 1 to 2?mm in diameter had distinct contaminant associations: Fe-cemented aggregates were elevated in As and Zn; Mn-cemented aggregates had more than five times as much Pb as the bulk soil; root channels were elevated in As; and charcoal particles were elevated in all contaminants, particularly Pb and Cd.

Conclusions

Results show that in wetland soils pedogenic processes differentially distribute contaminants amongst the redoximorphic features. The distribution is affected by landscape position and water table influence. At the pedon scale, there is an enrichment of As, Cd, Pb, and Zn in surface horizons, suggesting that upward flux of contaminants is occurring. This contaminant redistribution should be considered in design of management and remediation strategies.  相似文献   

遥控自动立木整枝机电源控制系统     

张俊梅  李文彬  撒潮  王德明 《北京林业大学学报》2007,29(4):22-26

便携式遥控自动立木整枝机控制系统电源的使用效率是整个系统的一个重要指标及可靠工作的前提.该文在分析控制逻辑的基础上,从节能的观点出发,合理地研制了自动立木整枝机发射与接收系统电源控制电路.电源供电能力测试的结果证明:该电源控制电路可以有效地提高整个系统电源的效率,能够很好地满足自动立木整枝机的工作需要.   相似文献   

芦荟粉对不同性别肉仔鸡免疫机能及生产性能的影响   总被引：1，自引：0，他引：1  

刘昊  佟建明  贾洪强  董晓芳  王长康  高微微  萨仁娜  张琪 《福建农业学报》2007,22(3):288-292

选用1日龄AA肉仔鸡共设雄性对照组(Ⅰ)、雄性芦荟粉组(Ⅱ)、雌性对照组(Ⅲ)和雌性芦荟粉组(Ⅳ)4个处理,Ⅰ、Ⅲ组饲喂基础日粮,Ⅱ、Ⅳ组均在基础日粮中添加600 mg.kg-1的芦荟粉。结果表明:雄性芦荟粉组比雄性对照组极显著降低了料肉比(P<0.01);21 d雄性芦荟粉组脾脏指数显著高于对照组(P<0.05);21 d雄性芦荟粉组新城疫血凝抑制效价显著高于对照组(P<0.05);42 d雄性芦荟粉组自然杀伤细胞杀伤活性极显著高于对照组(P<0.01)。说明日粮中添加芦荟粉可以提高肉仔鸡生产性能和免疫机能,且对雄性肉仔鸡生产性能和免疫机能影响效果优于雌性。  相似文献   

镉胁迫下黑曲霉TL-F2的促生特征及其对黑麦草种子萌发、幼苗生长和镉含量的影响     

刘如  董畅茹  张祎雯  屈铭慧  张伟  洒海洋  陈海燕  叶文玲  樊霆 《浙江农业学报》2021,33(2):326

以黑曲霉(Aspergillus niger)TL-F2为供试菌株,黑麦草为供试植物,研究Cd胁迫下A. niger TL-F2的促生特性,以及对黑麦草种子萌发、幼苗生长和Cd含量的影响。结果表明:与不加Cd的对照组相比,低浓度Cd(5 mg·L^-1)胁迫下,A. niger TL-F2产吲哚乙酸(IAA)和溶磷的能力无显著变化,但产铁载体的能力显著(P<0.05)降低48.18%;中(20 mg·L^-1)、高(50 mg·L^-1)浓度Cd胁迫下,A. niger TL-F2产IAA的能力分别显著(P<0.05)降低55.76%和65.69%,溶磷量分别显著(P<0.05)降低50.07%和78.19%,产铁载体的能力分别显著(P<0.05)降低69.71%和80.08%。接种高浓度(1×10⁸ mL^-1)A. niger TL-F2有助于促进Cd胁迫下黑麦草种子的萌发和生长,高浓度Cd胁迫下,黑麦草地上部Cd含量较不接菌的显著(P<0.05)增加,增幅为17.95%;接种低浓度(1×10⁶ mL^-1)A. niger TL-F2对黑麦草种子萌发、Cd含量无明显促进作用。综合来看,接种适当量的A. niger TL-F2有助于促进Cd胁迫下黑麦草种子的萌发和生长,增加黑麦草地上部Cd含量,可作为黑麦草修复Cd污染水体和土壤的强化措施。  相似文献   

牛心朴杀鼠活性初报   总被引：1，自引：2，他引：1  

贺春玲  韩崇选  张宏利  杨学军  王明春  杨清娥  撒文清 《西北林学院学报》2004,19(4):94-96,102

通过试管和圆形滤纸预试法初步确定了牛心朴(Cynanchum komarovii)乙醇提取液中含有生物碱、酚类物质、鞣质、皂甙、黄酮、甾体(或萜类)、糖、多糖(或甙类)和强心甙等成分。杀鼠活性的测定结果表明,乙醇提取液在饵料中的含量为15％时,小白鼠的平均食毒量为39．04g／kg,对小白鼠的毒杀率为100％;饵料中牛心朴粉的含量为15％和10％时,小白鼠的平均食毒量分别为26．61g／kg和29．27g／kg,对小白鼠的毒杀率分别为100％和90％;提取液中的化学成分基本包括了牛心朴杀鼠的活性成分,且适口性较原粉为好。  相似文献   

Arctic terrestrial biota: paleomagnetic evidence of age disparity with mid-northern latitudes during the late cretaceous and early tertiary     

Hickey LJ  West RM  Dawson MR  Choi DK 《Science (New York, N.Y.)》1983,221(4616):1153-1156

Magnetostratigraphic correlation of the Eureka Sound Formation in the Canadian high Arctic reveals profound difference between the time of appearance of fossil land plants and vertebrates in the Arctic and in mid-northern latitudes. Latest Cretaceous plant fossils in the Arctic predate mid-latitude occurrences by as much as 18 million years, while typical Eocene vertebrate fossils appear some 2 to 4 million years early.  相似文献