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31.
Journal of Soils and Sediments - Arsenic (As) is one of the most widespread toxic elements, affecting human health through consumption of contaminated water or food. This work studied the effects...  相似文献   
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ABSTRACT: The objective of the current study was to investigate (i) the outcome of experimentally induced Escherichia coli mastitis in primiparous cows during early lactation in relation with production of eicosanoids and inflammatory indicators, and (ii) the validity of thermography to evaluate temperature changes on udder skin surface after experimentally induced E. coli mastitis. Nine primiparous Holstein Friesian cows were inoculated 24 ± 6 days (d) after parturition in both left quarters with E. coli P4 serotype O32:H37. Blood and milk samples were collected before and after challenge with E. coli. The infrared images were taken from the caudal view of the udder following challenge with E. coli. No relationship was detected between severity of mastitis and changes of thromboxane B2 (TXB2), leukotriene B4 (LTB4) and lipoxin A4 (LXA4). However, prostaglandin E2 (PGE2) was related to systemic disease severity during E. coli mastitis. Moreover, reduced somatic cell count (SCC), fewer circulating basophils, increased concentration of tumor necrosis factor-α (TNF-α) and higher milk sodium and lower milk potassium concentrations were related to systemic disease severity. The thermal camera was capable of detecting 2-3°C temperature changes on udder skin surface of cows inoculated with E. coli. Peak of udder skin temperature occurred after peak of rectal temperature and appearance of local signs of induced E. coli mastitis. Although infrared thermography was a successful method for detecting the changes in udder skin surface temperature following intramammary challenge with E. coli, it did not show to be a promising tool for early detection of mastitis.  相似文献   
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A 12-year-old cow was presented with chronic respiratory disease and lameness. Chronic pleuritis, pneumonia, and bronchial carcinoma were found as well as periosteal proliferation on limb bones. Ancillary tests and necropsy confirmed a combined pathology of pulmonary inflammation and neoplasm, and hypertrophic pulmonary osteopathy.  相似文献   
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Intraoperative electrical stimulation, which temporarily inactivates restricted regions during brain surgery, can map cognitive functions in humans with spatiotemporal resolution unmatched by other methods. Using this technique, we found that stimulation of the right inferior parietal lobule or the caudal superior temporal gyrus, but not of its rostral portion, determined rightward deviations on line bisection. However, the strongest shifts occurred with subcortical stimulation. Fiber tracking identified the stimulated site as a section of the superior occipitofrontal fasciculus, a poorly known parietal-frontal pathway. These findings suggest that parietal-frontal communication is necessary for the symmetrical processing of the visual scene.  相似文献   
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An experiment was conducted in six earthen ponds with 20 shrimps m?2Litopenaeus stylirostris (Stimpson) during the warm season in New Caledonia to study the dynamics of wastes in relation with water exchange rate (WER). The nitrogen budget was established, taking into account the different forms of nitrogen in the water, sediment, feed and shrimp. Data from a wide range of treatments applied in unreplicated ponds were treated using regression analysis to establish the relationship between WER and partial nitrogen budget, sediment characteristics and shrimp performance. To compare effluent quality between treatments during the season, data were analysed using the non‐parametric sign test. The water outflow was characterized by a decrease in the concentrations of N‐mineral forms (TAN, NO2?–NO3?), an increase in the concentration of organic soluble and sestonic organic forms (expressed in terms of particulate nitrogen, particulate organic carbon, chlorophyll a) compared with the water inflow. Increasing WER increased the amount of exported wastes and mainly in the organic forms and TAN can be considered as negligible. The nitrogen budget showed that 19–46% of nitrogen input (feed+water) was exported into the coastal environment. The results showed that the quality of the sediment decreased as WER decreased. The potential negative impact of the developing industry in New Caledonia on the costal environment could be partially reduced in a first step by decreasing WER. However, if applied in the farms, this practice should be linked to a close survey of the evolution of sediment quality.  相似文献   
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The anatomy of the avian gastrointestinal (GI) tract is unique and significantly different from that of other animals. The characteristics of the avian GI tract allow the different species to adapt and thrive in their habitats. Infectious diseases of bacterial, viral, fungal, and parasitic origin commonly affect avian species. The significance and the nature of these pathologies vary with species and if they live in the wild or a captive environment. This review compiles information available in the literature on specific infectious processes that were considered relevant and clinically significant by the authors. Clinicians should be knowledgeable and aware of the infectious agents, clinical signs associated with disease, diagnostic techniques, and treatment methodologies currently available regarding diseases that affect the avian GI tract. Recent information that provides new insight to these infectious processes is the focus of this article.  相似文献   
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Atherosclerotic lesions are prevalent in companion psittacine species. Parrots account for much of the veterinary scientific information on avian atherosclerosis, but the lesions have been described in virtually all avian orders. This review presents a synthesis of the epidemiologic, clinical, diagnostic, and therapeutic information known in psittaciformes, at this time, which may help in the veterinary management of atherosclerotic diseases. The article further expands on nondomestic avian species for which information is restricted to pathologic and prevalence studies. A thorough knowledge of atherosclerosis is of the upmost importance for avian clinicians as the disease is common, affects most species of birds, and seems to be associated with captive lifestyles characterized by decreased activity and nonnative diets. Therefore, avian veterinarians are expected to be largely exposed to this chronic medical condition through patient presentation and should be prepared to properly manage this disease.  相似文献   
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BACKGROUND: Canine appendicular osteosarcoma (OSA) causes focal bone destruction, leading to chronic pain and reduced quality-of-life scores. Drugs that inhibit pathologic osteolysis might provide additional treatment options for managing cancer-induced bone pain. Aminobisphosphonates induce osteoclast apoptosis, thereby reducing pain associated with malignant osteolysis in human patients with cancer. HYPOTHESIS: Treatment of dogs with pamidronate administered intravenously will alleviate bone pain and reduce pathologic bone turnover associated with appendicular OSA in dogs. ANIMALS: Forty-three dogs with naturally occurring appendicular OSA administered pamidronate intravenously. METHODS: Prospective study. Therapeutic responses in dogs treated with pamidronate administered intravenously and nonsteroidal anti-inflammatory drugs (NSAID) were evaluated by using a numerical cumulative pain index score (CPIS), and by quantifying urine N-telopeptide (NTx) excretion and relative primary tumor bone mineral density (rBMD) assessed with dual energy x-ray absorptiometry. In addition, variables, including pamidronate dose, skeletal mass, baseline and change for CPIS, urine NTx and rBMD during treatment, and baseline tumor volume and radiographic pattern were compared between dogs clinically responsive and nonresponsive to pamidronate therapy. RESULTS: Twelve of 43 dogs (28%) had pain alleviation for >4 months, lasting a median of 231 days. Changes in CPIS and rBMD during treatment were statistically different between responders and nonresponders (P = .046 and .03, respectively). CONCLUSIONS AND CLINICAL IMPORTANCE: Substantiated by reductions in CPIS and increases in rBMD, single-agent pamidronate administered intravenously with NSAID therapy relieves pain and diminishes pathologic bone turnover associated with appendicular OSA in a subset of dogs.  相似文献   
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