Poliomyelitis in Monkeys: Decreased Susceptibility after Avoidance Stress     

Marsh JT  Lavender JF  Chang SS  Rasmussen AF 《Science (New York, N.Y.)》1963,140(3574):1414-1415

Eleven monkeys were subjected to avoidance stress for 24 hours followed immediately by intravenous inoculation with type I poliovirus. Twelve control monkeys not so stressed were similarly inoculated. Seven of 11 stressed animals survived the infection while only one of the controls lived and their average incubation period was significantly longer than the average for controls. The number of circulating lymphocytes decreased significantly in experimental animals during and immediately after exposure to stress.  相似文献   

PRESENTATION OF PROFESSOR MARSH'S COLLECTIONS TO YALE UNIVERSITY     

Marsh OC  Dwight T 《Science (New York, N.Y.)》1898,7(160):77-79

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Association of the HL-A7 cross-reacting group with a specific reaginic antibody response in allergic man   总被引：16，自引：0，他引：16  

D G Marsh  W B Bias  S H Hsu  L Goodfriend 《Science (New York, N.Y.)》1973,179(74):691-693

A relatively small proportion (17 percent) of individuals highly allergic to ragweed were found to develop marked reaginic (immunoglobulin E-mediated) skin sensitivity to a minor ragweed pollen allergen Ra5 (molecular weight 5200). Sensitivity to Ra5 was significantly associated with the possession of a major histocompatibility antigen of the HL-A7 cross-reacting group. This appears to be the first evidence of a strong association between a specific immune response and a specific group of closely related HL-A antigens in man.  相似文献   

Effect of monensin fed with forage on digestion and the ruminal ecosystem of steers.   总被引：25，自引：0，他引：25  

D A Donius  M E Simpson  P B Marsh 《Journal of animal science》1976,42(1):229-234

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Breeding and gestation facilities for swine. Matching biology to facility design.     

P D Ruen  G D Dial  D D Polson  W E Marsh 《Veterinary Clinics of North America: Food Animal Practice》1992,8(3):475-502

The rate-limiting phase of commercial swine production is breeding. The design of the breeding/gestation facilities influences the capacity of the producer to efficiently manage the breeding stock around the time of service and during the postservice period. Thus, breeding design potentially affects total born litter size and farrowing rates. In general, with original construction and facility renovation, the three principal activities of the breeding/gestation phase of production, (1) boar exposure/estrus detection, (2) breeding, and (3) gestation and pregnancy detection, should be independently considered.  相似文献   

Method of Selecting Preferred Baits and Rodenticides1     

W.E. Howard  R.E. Marsh 《EPPO Bulletin》1977,7(2):459-463

To conduct bait-choice tests, with species that will enter bait boxes, requires at least 10 bait boxes (25–40 cm long and about 20 cm deep) with openings at opposite corners, for exposing 3 to 5 trays of potential baits. Floors of boxes are dusted with a thin layer of talc or ground clay. The same boxes can be used to determine acceptance of the proven preferred bait treated with different rodenticides at different concentrations, except that different toxicants cannot be compared in the same box unless only chronic (multiple-feeding) anticoagulants are used. Tracking tunnels or stations can be used to obtain a relative pre- and post-control census of rodent populations. They are especially useful for determining whether there are survivors. If there axe survivors, the above non-toxic bait-acceptance tests and acceptance of prepared toxic bait tests must be repeated, for it is paramount to learn why the survivors were not poisoned.  相似文献   

The effect of seven substituted urea herbicides on the soil microflora     

Erna Grossbard  John A. P. Marsh 《Pest management science》1974,5(5):609-623

Chloroxuron, diuron, fluometuron, metobromuron and monuron added to soil at 500 parts/million a.i. on a dry weight basis caused an initial stimulation of CO₂ production, followed by indications of inhibition. Nitrification was clearly inhibited, particularly by monuron and metobromuron. Metoxuron at 5 and 50 parts/million a.i. had no effect on CO₂ output and nitrification, but at 500 parts/million a.i. both were greatly reduced. Numbers of fungal propagules were temporarily lower at 50 parts/million a.i., and severely curtailed at 500 parts/million a.i. but total counts of bacterial propagules were greatly increased. Linuron had an inhibitory effect on CO₂ evolution at 500 parts/million a.i. but this varied in extent and duration; some reduction was also found at 50 parts/ million a.i. At 500 parts/million a.i. there was no effect on mineralisation of N but in soil supplemented with ammonium sulphate nitrification was reduced. Changes in microbial equilibrium occurred, but were less marked than with metoxuron. Cellulose decomposition was also reduced. Small amounts of 3,4dichloroaniline were found in linuron-treated soils, but microbial activities were not affected when 5 parts/million 3,4-dichloroaniline was added to the soil. However, at 140 parts/million microbial activities were affected adversely, but in a different pattern to that for linuron; nitrification was severely reduced, but numbers of fungal propagules were hardly affected, suggesting that the effects observed in linuron-treated soil were not due to this metabolite.  相似文献   

Effects of zero and three-day storage of washed boar spermatozoa on subsequent incubation characteristics     

C W Foley  H M Marsh  C J Heidenreich  V A Garwood  R E Erb 《Journal of animal science》1967,26(5):1072-1077

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The 1976 nobel prize for physiology or medicine     

Marsh RF 《Science (New York, N.Y.)》1976,194(4268):927-929

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Anti-protozoal efficacy of high performance liquid chromatography fractions of Torilis japonica and Sophora flavescens extracts on Neospora caninum and Toxoplasma gondii     

Youn HJ  Lakritz J  Rottinghaus GE  Seo HS  Kim DY  Cho MH  Marsh AE 《Veterinary parasitology》2004,125(3-4):409-414

We previously reported that alcoholic extracts of Sophora flavescens and Torilis japonica from South Korea demonstrated good efficacy in reducing replication of Toxoplasma gondii and Neospora caninum. To characterize the chemical component associated with anti-protozoal activity, specific fractions were isolated by high performance liquid chromatography (HPLC) and used for in vitro testing. These fractions were evaluated in vitro against T. gondii and N. caninum. Fractions of the herb extracts were serially diluted to final concentrations of 2.850 to 0.356 ng/ml in medium and added to wells containing replicating T. gondii and N. caninum. To determine the ability of each fraction to inhibit parasite proliferation, 3H-uracil incorporation was used to determine parasite replication. In cultures infected with T. gondii, a fraction of T. japonica (TJ2) inhibited T. gondii proliferation by 99.2, 94.4, 88.6 and 27.0% in the range from 2.850 to 0.356 ng/ml. Four fractions of S. flavescens (SF1-SF4) inhibited T. gondii proliferation by 99.6-60.6, 96.9-48.1, 92.3-68.2 and 95.4-52.9% in the range from 2.850 to 0.356 ng/ml. In cultures infected with N. caninum, a fraction of T. japonica (TJ2) inhibited N. caninum proliferation by 98.3, 95.5, 79.7 and 30.6% in the range from 2.850 to 0.356 ng/ml. Four fractions of S. flavescens (SF1-SF4) inhibited N. caninum proliferation by 97.1-25.9, 94.8-35.5, 95.9-33.7 and 95.4-49.4% in the range from 2.850 to 0.356 ng/ml. These fractions of T. japonica and S. flavescens extracts are currently undergoing in vivo evaluation in experimentally infected mice.  相似文献