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31.
Supermassive black hole binaries may exist in the centers of active galactic nuclei such as quasars and radio galaxies, and mergers between galaxies may result in the formation of supermassive binaries during the course of galactic evolution. Using the very-long-baseline interferometer, we imaged the radio galaxy 3C 66B at radio frequencies and found that the unresolved radio core of 3C 66B shows well-defined elliptical motions with a period of 1.05 +/- 0.03 years, which provides a direct detection of a supermassive black hole binary. 相似文献
32.
Hayashi S. Jinbo T. Iguchi K. Shimizu M. Shimada T. Nomura M. Ishida Y. Yamamoto S. 《Veterinary research communications》2001,25(2):117-120
The concentrations of C-reactive protein (CRP) and 1-acid glycoprotein (AAG) were evaluated in 1-, 3- and 18-month-old dogs (four of each age) that had been inoculated with turpentine oil. The CRP and AAG in 3-month-old and younger dogs subjected to surgery or inoculated with either Staphylococcus aureus or a viral vaccine were also evaluated. The average CRP concentration in the sera peaked 2 days after inoculation of turpentine oil. The peak CRP concentrations in 3- and 18-month-old dogs were significantly (p<0.05) greater than those in 1-month-old dogs. The average AAG concentration in the sera peaked 4 days after inoculation of turpentine oil. No significant difference was found in AAG concentrations between any of the age groups. When experimentally inoculated with S. aureus or subjected to oophorohysterectomy, the CRP and AAG concentrations increased in 3-month-old dogs, but they increased little in 1-month-old dogs. The CRP and AAG in dogs inoculated with the viral vaccine did not increase. In dogs with fractures or subjected to percutaneous gastrostomy, the CRP and AAG concentrations correlated with the condition of dogs. 相似文献
33.
S Fukumoto K Etani K Toi M Hanadate M Hidaka K Yokoya T Hiramatsu T Iguchi S Kudo K Miyamoto 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1990,52(2):379-385
The prevalence and intensity of infection with abomasal nematodiasis was studied in dairy cattle of Hokkaido, northern Japan, for successive two years. During the period of March in 1985 to September in 1987, a total number of 393 abomasa of Holstein-Friesian cows was examined for nematode parasites. Nematodes were detected from 75% of the cows. The prevalence of nematode species detected was Ostertagia ostertagi 250 (63.6%), Mecistocirrus digitatus 181 (46.1%), Trichostrongylus axei 85 (21.6%) and Haemonchus sp. 1 (0.3%). The prevalence and population composition of each growth stage varied seasonally in O. ostertagi and M. digitatus. The large percentage of arrested larvae, early L4 O. ostertagi and immature L5 M. digitatus, detected during the mid-winter and the increasing percentage of matured adult populations of both species in early spring revealed the occurrence of the autumn associated arrested development (hypobiosis) phenomenon in bovine abomasum nematodes of Japan. 相似文献
34.
Shimada T Ishida Y Shimizu M Nomura M Kawato K Iguchi K Jinbo T 《Veterinary research communications》2002,26(3):171-177
The concentrations of C-reactive proteins (CRP) in the plasma of five beagle dogs experimentally inoculated with Ehrlichia canis increased markedly. The concentrations began to increase between 4 and 16 days and peaked between 15 and 42 days after inoculation of E. canis. The peak concentrations ranged from 217.8 to 788.8 g/ml (452.6±228.1 SD). After the peak, the concentrations of CRP decreased rapidly. The PCR product of 16S rRNA of E. canis became detectable in the five dogs between 18 and 27 days after inoculation of E. canis. Antibodies to E. canis were detected in plasma from the dogs between 5 and 15 days after inoculation of E. canis. The timings of seroconversion and of the start of the increase in CRP were approximately similar and the high concentrations of CRP in the plasma of the dogs tended to become apparent when the PCR product of 16 S rRNA of E. canis became detectable. 相似文献
35.
Kobayashi T Takita Y Suzuki A Katsu Y Iguchi T Ohta Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2008,70(1):115-118
ORP150 is a hypoxic stress-induced protein located in the endoplasmic reticulum. Transgenic mice overexpressing ORP150 (ORP-Tg) exhibit vacuolar degeneration in the heart. To determine whether vacuolization is present in skeletal muscle, we pathologically examined ORP-Tg mice. After 60 days of age, severe vacuolization was found in the soleus muscles of the hind legs of the ORP-Tg mice. Immunohistochemical staining of ORP150 revealed co-localization of ORP150 and vacuolization in the affected cells. Electron microscopy revealed a marked increase in the number of rough-surfaced endoplasmic reticula (rER) and distention of the cisterna. These findings suggest that overexpression of ORP150 causes accumulation of ORP150 in the rER, resulting in vacuolar degeneration in the skeletal muscle of ORP-Tg mice. 相似文献
36.
Yasutomo Hori Masayuki Iguchi Yasuhiro Heishima Yohei Yamashita Kensuke Nakamura Atsushi Hirakawa Akihito Kitade Toshiki Ibaragi Michio Katagi Tamotsu Sawada Masashi Yuki Nobuyuki Kanno Haruki Inaba Noriko Isayama Hideyuki Onodera Naoki Iwasa Mikio Kino Mikihiro Narukawa Syuhei Uchida 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(3):922-929
37.
We examined the effects of interstitial space between stream substrate particles on the colonization of aquatic organisms using three types of substrates (gravel, a cobble, and a cobble on gravel) in a riffle and pool of a temperate stream. Significantly greater abundance, wet weight, diversity (H′), taxonomic richness, and evenness of aquatic organisms were found in the riffle than in the pool, and the interstitial space substrate (i.e., a cobble on gravel) had significantly greater abundance, wet weight, and taxonomic richness of aquatic organisms than did the cobble substrate. Of the 13 families observed in the experiments, larval net-spinning caddisfly (Hydropsychidae) dominated the riffle in terms of the abundance and wet weight; chironomid larvae dominated both the riffle and the pool in terms of abundance. Simple main effect tests indicated significant effects of substrate on the abundance and wet weight of larval caddisfly in the riffle, and post hoc tests on substrate in each habitat indicated that the abundance and wet weight of larval caddisfly on interstitial space substrate were significantly greater than those on cobble substrate in the riffle. Our results suggest the importance of interstitial space between stream substrates in riffles to ensure higher colonization rates of aquatic organisms such as larval net-spinning caddisflies characterized as filter feeders. 相似文献
38.
Ryota Suwa Masako Nakamura Masaya Morita Kazuaki Shimada Akira Iguchi Kazuhiko Sakai Atsushi Suzuki 《Fisheries Science》2010,76(1):93-99
Ocean acidification, caused by increased atmospheric carbon dioxide (CO2) concentrations, is currently an important environmental problem. It is therefore necessary to investigate the effects of ocean acidification on all life stages of a wide range of marine organisms. However, few studies have examined the effects of increased CO2 on early life stages of organisms, including corals. Using a range of pH values (pH 7.3, 7.6, and 8.0) in manipulative duplicate aquarium experiments, we have evaluated the effects of increased CO2 on early life stages (larval and polyp stages) of Acropora spp. with the aim of estimating CO2 tolerance thresholds at these stages. Larval survival rates did not differ significantly between the reduced pH and control conditions. In contrast, polyp growth and algal infection rates were significantly decreased at reduced pH levels compared to control conditions. These results suggest that future ocean acidification may lead to reduced primary polyp growth and delayed establishment of symbiosis. Stress exposure experiments using longer experimental time scales and lower levels of CO2 concentrations than those used in this study are needed to establish the threshold of CO2 emissions required to sustain coral reef ecosystems. 相似文献
39.
A 20-kDa protein toxin (bandaporin) was isolated from the sea anemone Anthopleura asiatica (Actiniidae) using the precipitation of ammonium sulfate saturation, and ion-exchange and gel-permeation chromatographies.
Bandaporin showed potent hemolytic activity (EC50 value: 8.8 ng/ml to 0.8% suspension of sheep red blood cells) and lethal toxicity to crayfish (LD100 value: 0.58 mg/kg). The hemolytic activity of bandaporin was inhibited specifically by sphingomyelin. Eight other tested
membrane lipids, including cholesterol, and gangliosides GM1 and GM2, did not inhibit bandaporin hemolytic activity. Antimicrobial
and phospholipase A2 (PLA2) activities were not detected in bandaporin. The complementary DNA (cDNA) encoding bandaporin was sequenced and the deduced
amino acid sequence of bandaporin revealed that this actinoporin had not been previously characterized. Actinoporins are cytolytic
peptide toxins that are widely distributed in Actiniidae and Stichodactylidae sea anemones. This study was the first characterization
of an actinoporin from a sea anemone of the genus Anthopleura. 相似文献
40.
Keiichiro Iguchi Kogi Ogawa Masaki Nagae Fuminari Ito 《Aquaculture (Amsterdam, Netherlands)》2003,220(1-4):515-523
The impact of coldwater disease caused by Flavobacterium psychrophilum is a recent important problem in the farming of ayu (Plecoglossus altivelis). We hypothesized that stress from high-rearing densities predisposes fish to disease by reducing their immunocompetence, and we sought to reduce fish losses by introducing an alternative culture regime. Fish enclosed at three densities (1250 fish or 8.0 kg, 400 fish or 2.6 kg and 100 fish or 0.6 kg/m3) were examined. Fish in the high-density treatment exhibited more elevated serum cortisol concentrations and more suppressed serum immunoglobulin M (IgM) concentrations accompanied by higher mortality, possibly caused by coldwater disease, than those in the medium- and low-density treatments. These results indicate that high-rearing densities stress fish and evoke subsequent physiological responses which have maladaptive effects. We propose that coldwater disease may be prevented by improving the disease resistance of fish by using moderate stocking densities. 相似文献