Guidelines for handling antineoplastic and immunosuppressive drugs     

ADJ WATSON  AE PEASTON  R MALIK  GR SWINNEY 《Australian veterinary journal》1997,75(12):868-876

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Polyarthritis in wild mice (Mus musculus) caused by Streptobacillus moniliformis     

JD TAYLOR  CP STEPHENS  RG DUNCAN†  GR SINGLETON† 《Australian veterinary journal》1994,71(5):143-145

SUMMARY Mice trapped on farms in south-eastern Queensland had chronic abscessating osteoarthritides mainly involving the carpi and tarsi. Pleomorphic bacteria were shown by silver staining to be plentiful within lesions. Streptobacillus moniliformis was isolated from the joints, and streptobacillary polyarthritis was diagnosed. Other lesions observed included subcutaneous and hepatic abscesses.  相似文献   

Seroprevalence to Leptospira interrogans serovar hardjo in Merino stud rams in South Australia     

GR ELLIS  DL PARTINGTON†  M. HINDMARSH‡  MD BARTON 《Australian veterinary journal》1994,71(7):203-206

Summary A serological survey of 2160 Merino stud rams on 36 farms detected positive reactions greater than or equal to 1/100 in 42% of animals using the microscopic agglutination test (MAT) to Leptospira interrogans serovar hardjo. Twenty flocks had seroprevalence values greater than 30% with 15 flocks having values 60%. The enzymelinked immunosorbent assays showed that 47% and 3% of rams on the 36 farms were positive for IgG and IgM antibodies, respectively. Forty-five percent of hardjo reactions were in rams that had not been exposed to cattle. Significant correlations were found between IgM reactors and creek/dam water pumped into troughs, and between MAT/IgG reactors and total flock size. No statistical relationships were detected between positive reactors and two different annual average rainfall gradients, the time of the year in which samples were obtained, or agricultural regions of South Australia. Infections with an organism of the Sejroe serogroup is widespread in Merino stud rams.  相似文献   

Temporal Relationships and Repeatability of Follicle Diameters and Hormone Concentrations within Individuals in Mares     

JC Jacob  EL Gastal  MO Gastal  GR Carvalho  MA Beg  OJ Ginther 《Reproduction in domestic animals》2009,44(1):92-99

Data were collected daily from 23 mares during two consecutive interovulatory intervals (IOIs). Several significant (p < 0.05) new observations on temporal relationships were made. The FSH increase that begins before ovulation temporarily plateaued on the day of discharge of follicular fluid into the peritoneal cavity in association with ovulation. During the declining portion of the pre-ovulatory oestradiol surge, an abrupt reduction in the rate of decrease occurred in synchrony with the peak of the LH surge and is consistent with a negative effect of LH on oestradiol. Repeatability within mares was based on the following positive and significant correlations between the two IOIs: (i) length of the interval between ovulations and between ovulation and the beginning of follicle deviation; (ii) diameter of the pre-ovulatory follicle on days -3 to -1; (iii) number of follicles in diameter classes of 2–5 mm (correlation for 22/23 days of the IOI), 5.1–10 mm (18/23 days), 10.1–15 mm (12/23 days) and 15.1–20 mm (12/23 days) and (iv) concentrations of FSH (18/23 days) and LH (22/23 days). The greatest repeatability for the follicle-diameter classes occurred in the 2–5 mm class, and thereafter the repeatability progressively decreased as the diameters for the classes increased. Results demonstrated measurable repeatability within mares for several end points between consecutive IOIs.  相似文献   

Maximum Water Temperature Limit in Open-Water Swimming Events     

Filippo Macaluso  Rosario Barone  Ashwin W. Isaacs  Felicia Farina  Giuseppe Morici  Valentina Di Felice 《The Forestry Chronicle》2014,25(2):245-246

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Growth response to increasing doses of microencapsulated vitamin B12 and related changes in tissue vitamin B12 concentrations in cobalt-de cient lambs     

ND Grace  SO Knowles  GR Sinclair  J Lee 《New Zealand veterinary journal》2013,61(2):89-92

AIM: To investigate growth responses of cobalt-deficient lambs to increasing doses of microencapsulated vitamin B₁₂, and to measure associated changes in serum and liver vitamin B₁₂ concentrations over 243 days.

METHODS: From a flock grazing pastures that had low cobalt (Co) levels (about 0.06 mg Co/kg dry matter), 4-6-week-old lambs (n=137) were assigned to four groups and received either no treatment or a subcutaneous injection of 3.0, 4.5 or 6.0 mg of microencapsulated vitamin B₁₂ on Day 1. At approximately monthly intervals, all lambs were weighed and blood samples were collected from a selection (n=10) of monitor animals, up to Day 243. Liver biopsies were also carried out on the monitor lambs (n=8) on Days 1, 124 and 215.

RESULTS: The vitamin B₁₂-treated lambs grew significantly faster (p<0.001) than untreated animals. Liveweights after 243 days were 28, 45, 45 and 47 kg for the untreated, 3.0, 4.5 and 6.0 mg vitamin B₁₂-treated lambs, respectively. Of the initial group of untreated lambs, 68% had to be removed before the end of the trial because of substantial weight loss, but none of the treated animals were similarly afflicted. Serum vitamin B₁₂ concentrations increased in all vitamin B₁₂-treated lambs, reaching a peak at Day 25, and those of the 4.5 and 6.0 mg vitamin B₁₂-treated lambs remained significantly higher (except at Day 124) than the untreated lambs to Day 187. However, at Day 124, but not Day 215, the liver vitamin B₁₂ concentrations of treated lambs were two to three times higher than those of controls.

CONCLUSIONS: The growth rates of Co-deficient lambs were markedly improved by injection of 3.0, 4.5 or 6.0 mg of microencapsulated vitamin B₁₂, and liveweights were maintained for at least 243 days. Serum vitamin B₁₂ concentrations were related to this growth response; concentrations of <220 pmol vitamin B₁₂/l were associated with a 95% probability that lambs were Co-deficient and would thus respond to Co/vitamin B₁₂ supplementation. Based on these data, the current New Zealand reference criteria for Co deficiency should be reviewed.

CLINICAL SIGNIFICANCE: An injection of 3 mg microencapsulated vitamin B₁₂2 given to lambs at tailing will treat Co deficiency and will increase and maintain liveweights in a flock for up to 8 months.  相似文献   

The effects of large doses of soluble and insoluble forms of cobalt given at monthly intervals on cobalt deficiency disease in lambs     

E.D. Andrews M.Sc. A.N.Z.I.C.  B.J. Stephenson  C.E. Isaacs B.V.Sc.  R.H. Register 《New Zealand veterinary journal》2013,61(11):191-196

Extract

A large number of related compounds, all based on the prototype parent compound thiabendazole are now available on the market, each one claiming distinct advantages and applications for anti-parasitic use. The ever increasing number of benzimidazoles appearing regularly is a good example of so called molecular manipulation of molecular roulette whereby individual pharmaceutical companies endeavour to compete with a rival company's successful product without breaching the patent rights of a particular compound.  相似文献   

Supermarket power, own-labels, and manufacturer counterstrategies: international relations of cooperation and competition in the fruit canning industry   总被引：1，自引：0，他引：1  

Libby Hattersley  Bronwyn Isaacs  David Burch 《Agriculture and Human Values》2013,30(2):225-233

Growing supermarket dominance and the expansion of own-label market share in Australia has put considerable pressure on agri-food manufacturers, and the recent movement of a number of manufacturing operations off-shore has attracted widespread attention. This paper examines the pursuit of an international manufacturing base by SPC Ardmona, one of Australia’s major fruit and vegetable processors, with a focus on strategic alliances formed with Siam Foods in Thailand and Rhodes Food Group in South Africa/Swaziland. Strategic horizontal alliances have become increasingly important for manufacturers seeking to counter retailer dominance, yet have received little attention in the agri-food literature. The two alliances examined in this paper illustrate the profound importance of prevailing societal and institutional environments in which production networks ‘touch-down’, and their influence on firm-level dynamics of trust, motivation, corporate values, and strategic objectives. Horizontal alliances can offer a promising alternative to cut-throat competition and a ‘race- to-the-bottom’ between agri-food manufacturers. However, with own-label sourcing strategies deepening competition between geographically-disparate manufacturers, identifying compatible alliance partners is likely to become an increasingly greater challenge.  相似文献   

Adverse drug interactions of importance in veterinary practice     

P E Reilly  J P Isaacs 《The Veterinary record》1983,112(2):29-33

Multiple drug therapy is often used in veterinary practice; occasionally, inappropriate combinations of drugs may be administered which interact to produce adverse responses. Such interactions may occur in vitro because of physically or chemically incompatible drugs having been mixed before administration or in vivo. A number of important in vitro incompatibilities concerning parenteral drugs are tabulated, consideration having been given both to problems attending the use of intravenous fluids as vehicles for their administration and to incompatibilities between the drugs themselves. Interactions which occur in vivo are also examined; these have been grouped according to the various mechanisms by which they occur.  相似文献   

Interactions Between Nutrition and Reproduction in the Pig     

JR Cosgrove    ST Charlton    SJ Cosgrove    W. Zak  GR Foxcroft 《Reproduction in domestic animals》1995,30(4):193-200

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