Infertility associated with the absence of endometrial progesterone receptors in a bitch          下载免费PDF全文

JC Dockweiler  B Cossic  CG Donnelly  RO Gilbert  E Buckles  SH Cheong 《Reproduction in domestic animals》2017,52(1):174-178

A three‐year‐old intact female Old English sheepdog was presented for evaluation of infertility. A uterine biopsy was performed during dioestrus, and the microscopic appearance was inconsistent with progesterone stimulation; the glands were sparse, simple and failed to show coiling, while the glandular epithelium was cuboidal instead of columnar. There was very little evidence of glandular activity. Due to the inappropriate appearance of the glands for the stage of the cycle, immunohistochemistry for progesterone receptors was performed. No progesterone receptor‐positive immunoreactivity was identified in the endometrial luminal epithelium, glandular epithelium or stroma. Weak intranuclear immunoreactivity was identified within the smooth muscle cells of the myometrium. The absence of progesterone receptors within the endometrial glands is the most likely explanation for the abnormal appearance of the endometrium and for this bitch's infertility. To our knowledge, this is the first report of endometrial progesterone receptor absence in a bitch.  相似文献   

Cattle and Carnivore Coexistence in Alberta: The Role of Compensation Programs     

Tracy Lee  Kim Good  Winston Jamieson  Michael Quinn  Ashok Krishnamurthy 《Herpetological Monographs》2017,39(1):10-16

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Reliance on lakes by salmon,trout and charr (Oncorhynchus,Salmo and Salvelinus): An evaluation of spawning habitats,rearing strategies and trophic polymorphisms     

Martin C. Arostegui  Thomas P. Quinn 《Fish and Fisheries》2019,20(4):775-794

Salmonid fishes may reside within or migrate between stream and lake habitats, or undergo anadromous migrations between freshwater and the ocean. While the degree of anadromy of salmonids has been thoroughly compared, no analogous review has examined the degree of lake use. To assess the extent of reliance on lake habitat in this family, we considered 16 species of salmon, trout and charr from the genera Oncorhynchus, Salmo and Salvelinus, comparing their (a) use of lakes as spawning habitat, (b) rearing strategies in lakes, and (c) occurrence and diversity of lacustrine trophic polymorphism. In identifying the primary life‐history patterns of each species and exploring the lesser‐known lacustrine behaviours, we found that the extent of reliance on lakes exhibits a negative association with the degree of anadromy. Oncorhynchus rely least on lakes, Salmo to an intermediate level and Salvelinus the most, opposite of the general prevalence of anadromy among these genera. Lakes are critical to adfluvial and lake‐resident salmonids, but they also support anadromous and fluvial life histories by providing spawning, rearing, overwintering and/or summer refuge habitat. Adfluviality, although a non‐anadromous life history, consists of similar migration‐related traits and behaviours as anadromy, including the parr–smolt transformation, sex‐biased patterns of migration and residency, and the presence of precocious males. Lakes support life‐history variants, reproductive ecotypes and trophic morphs unique to lacustrine habitat. Therefore, conservation of salmonids is dependent on maintaining the diversity and quality of their habitats, including lakes.  相似文献   

Transformation toward agricultural sustainability in New Zealand hill country pastoral landscapes   总被引：1，自引：0，他引：1  

M.B. Dodd  M.E. Wedderburn  T.G. Parminter  B.S. Thorrold  J.M. Quinn 《Agricultural Systems》2008

A multi-stakeholder representative group was established to oversee a project examining the economic and environmental performance of a representative North Island hill country catchment farm at Whatawhata in the western Waikato region of New Zealand. The group included representation from landowners, government agencies and scientists. The group was facilitated through an action research approach incorporating three phases: (1) awareness; (2) forecasting; and (3) implementation. The group identified a set of goals and indicators relevant to achieving a “well managed rural hill catchment” The indicators were used to (a) assess the current state of the catchment farm in relation to the goals; (b) evaluate a range of strategies for improving system performance and (c) evaluate progress toward the goals following land use changes implemented within the catchment farm. Key issues for the group included the availability of data and the setting of appropriate performance benchmarks. From both economic and environmental points of view, the existing farm system was failing to meet the goals set by the management group. Key factors driving these outcomes included the physical and productivity limitations of the soil resource, poor livestock performance and poor water quality. A mixture of research observations, decision support models and expert stakeholder knowledge indicated scope for improving performance through forestry, riparian management, erosion control and livestock intensification options. Based on their evaluation of the forecasting results, the group developed a new land use plan, which depended on significant capital investment in land use and enterprise change. Subsequent monitoring of soils, vegetation, water quality, animal production and financial results over four years showed marked improvement in a number of key performance indicators. In particular, sediment and phosphorus loads and faecal coliform levels decreased rapidly, native forest fragments showed early signs of restoration, lamb and beef productivity increased and the per hectare financial returns of the pastoral component increased. Better matching of land use to land capability has led to short-term improvement in some aspects of the economic and environmental performance of the catchment farm. Progress toward a more sustainable agricultural system was achieved, but at a substantial cost for transformation of the biophysical system, which has implications for the wider sector.  相似文献   

Organic carbon fluxes and ecological recovery from the cretaceous-tertiary mass extinction     

S D'Hondt  P Donaghay  JC Zachos  D Luttenberg  M Lindinger 《Science (New York, N.Y.)》1998,282(5387):276-279

Differences between the carbon isotopic values of carbonates secreted by planktic and benthic organisms did not recover to stable preextinction levels for more than 3 million years after the Cretaceous-Tertiary mass extinction. These decreased differences may have resulted from a smaller proportion of marine biological production sinking to deep water in the postextinction ocean. Under this hypothesis, marine production may have recovered shortly after the mass extinction, but the structure of the open-ocean ecosystem did not fully recover for more than 3 million years.  相似文献   

Photonic band gap guidance in optical fibers   总被引：3，自引：0，他引：3  

JC Knight  J Broeng  TA Birks  PSJ Russell 《Science (New York, N.Y.)》1998,282(5393):1476-1478

A fundamentally different type of optical waveguide structure is demonstrated, in which light is confined to the vicinity of a low-index region by a two-dimensional photonic band gap crystal. The waveguide consists of an extra air hole in an otherwise regular honeycomb pattern of holes running down the length of a fine silica glass fiber. Optical fibers based on this waveguide mechanism support guided modes with extraordinary properties.  相似文献   

Room temperature-operating spin-valve transistors formed by vacuum bonding     

DJ Monsma  R Vlutters  JC Lodder 《Science (New York, N.Y.)》1998,281(5375):407-409

Functional integration between semiconductors and ferromagnets was demonstrated with the spin-valve transistor. A ferromagnetic multilayer was sandwiched between two device-quality silicon substrates by means of vacuum bonding. The emitter Schottky barrier injected hot electrons into the spin-valve base. The collector Schottky barrier accepts only ballistic electrons, which makes the collector current very sensitive to magnetic fields. Room temperature operation was accomplished by preparing Si-Pt-Co-Cu-Co-Si devices. The vacuum bonding technique allows the realization of many ideas for vertical transport devices and forms a permanent link that is useful in demanding adhesion applications.  相似文献   

Pre‐planting weed detection based on ground field spectral data     

Luan P Pott  Telmo JC Amado  Raí A Schwalbert  Elodio Sebem  Mithila Jugulam  Ignacio A Ciampitti 《Pest management science》2020,76(3):1173-1182

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Transcriptional and proteomic analysis of endometrial and conceptus responses to cloprostenol administration in the third week of pregnancy     

Tony Hayes  Bette Anne Quinn  Brandon Lillie  Leah Schutt  Meagan Moeyaert  Rudolf Waelchli  Keith Betteridge 《Journal of Equine Veterinary Science》2012

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Application of the Enfer chemiluminescent multiplex ELISA system for the detection of Mycobacterium bovis infection in goats     

Shuralev E  Quinn P  Doyle M  Duignan A  Kwok HF  Bezos J  Olwill SA  Gormley E  Aranaz A  Good M  Davis WC  Clarke J  Whelan C 《Veterinary microbiology》2012,154(3-4):292-297

A study was conducted to optimise a multiplex serological immunoassay for use in identification of goats infected with Mycobacterium bovis. To assess assay specificity, 31 goats with a history of being free from M. bovis infection were used. To determine assay sensitivity, 180 Single Intradermal Comparative Tuberculin test (SICTT) positive goats were recruited. Additionally, 286 SICTT negative goats classed as potentially exposed animals present in the same positive herds were also included in the study. The results of the assay demonstrated a specificity of 100%. The multiplex assay detected 57/60 SICTT (95.0%) positive animals in one M. bovis infected herd and 120/120 (100%) in a second herd. In a separate experiment, 28 M. caprae culture confirmed infected goats from Spain were assayed, of which 24 (85.7%) were found positive in the test. The results show that inclusion of an antibody based assay can improve the ability to identify M. bovis and M. caprae infected goats. With further development and validation the multiplex assay may prove to be a useful tool for control of M. bovis and M. caprae infection in goats.  相似文献