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A study was conducted in the USA to determine whether transmissible gastroenteritis (TGE) virus could be transmitted from carcases of slaughtered pigs. Transmissible gastroenteritis virus was transmitted to 6-day-old piglets by dosing with homogenates of muscle and lymph node collected from 500 clinically normal pigs at the time of slaughter. All piglets in 2 separately housed litters showed clinical signs of TGE with 5 piglets dying within 10 d of oral dosing with homogenates. Transmissible gastroenteritis virus was isolated from 2 of these piglets and all piglets developed TGE antibody. Transmissible gastroenteritis virus was not isolated in tissue culture from muscle and lymph node homogenates, but was isolated from 4 (0.8%) of 500 tonsil samples collected from the same pigs. A survey of 250 serum samples provided an estimate of the prevalence of slaughtered pigs with TGE antibody of 34.8% in the sample population. The results indicate that carcases of some pigs from TGE endemic areas contain viable TGE virus, and that there would be a substantial risk of introducing TGE virus into Australia by the importation of uncooked pig meat from these areas. 相似文献
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KELLY L. CARLSON M. KEITH CHAFFIN WAYNE V. CORAPI KAREN F. SNOWDEN DAVID G. SCHMITZ 《Veterinary radiology & ultrasound》2011,52(5):568-572
The starry sky hepatic pattern is an unusual ultrasonographic appearance of equine liver characterized by numerous small, hyperechoic foci, some of which cast an acoustic shadow, distributed randomly throughout the hepatic parenchyma. Our objectives were to describe the signalment, clinical signs, clinicopathological findings, primary disease process, and ultrasonographic findings of horses with this ultrasonographic pattern, as well as determine the associated gross and histologic changes. The starry sky pattern was identified in 18 adult horses of mixed gender and breed. The horses had various clinical signs, with weight loss and anorexia reported most commonly. Liver size and parenchymal echogenicity were normal in most horses. The hyperechoic foci frequently caused acoustic shadowing. Biliary dilation was noted rarely. The ultrasonographic pattern was the result of numerous fibrosing hepatic granulomas in all horses evaluated histologically. γ‐Glutamyltransferase was the most commonly elevated hepatic enzyme, though it was increased in fewer than half the horses. Fifteen horses had an additional disease that was identified as the apparent cause of clinical signs. Three horses had primary hepatic disease while 12 had diseases of other body systems. Therefore, the starry sky ultrasonographic pattern is likely incidental in most horses and not clinically significant. Improved recognition of this pattern and further investigation of affected horses may help refine the etiology and clinical significance of the granulomas. 相似文献
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Clinical and pathological features are described in seven young Soft-coated Wheaten Terriers with chronic renal disease. The oldest dog was 21/2 years; in the other six, ages at death ranged from one to 15 months. Two of the puppies were littermates: one died at 4 weeks, the other at 12 months. Two of the dogs were examined at intervals up to 14 months, during which time there was progressive deterioration in renal function. All seven dogs had abnormal kidneys with cortical narrowing. The histological features were not consistent and included: tubular dilatation and basement membrane thickening; an unusually large proportion of immature glomeruli; persistence of interstitial connective tissue resembling foetal mesenchyme. Inflammatory change was minimal except in two dogs with super-imposed pyelonephritis. The clinical and laboratory data suggest that these dogs had dysplasia of the kidneys that progressed to chronic renal disease during early life. In three dogs there was a familial relationship. 相似文献
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D. F. KELLY SUSAN E. LONG GAIL D. STROHMENGER† 《The Journal of small animal practice》1976,17(4):247-253
A 9-year-old male, pseudohermaphrodite Labrador had intermittent urinary incontinence and haematuria. Laparotomy revealed two neoplastic intra-abdominal testes and a uterus which communicated with the urethra. Seminoma and Sertoli cell tumours were found in the testes. 相似文献