Gentamicin sulfate in the horse: serum, synovial, peritoneal, and urine concentrations after single dose intramuscular administration     

M. P. BROWN  SUSAN M. STOVER  R. H. KELLY  T. B. FARVER 《Journal of veterinary pharmacology and therapeutics》1982,5(2):119-122

Ten healthy adult mares were given a single intramuscular dose (2.2 mg/kg) of gentamicin sulfate. Over a 48-h period, gentamicin concentrations were measured serially in the serum of all ten mares and in synovial fluid, peritoneal fluid, and urine of six of the mares. The mean peak serum gentamicin concentration was 5.73 μg/ml at 1 h. Gentamicin was detected in synovial fluid and peritoneal fluid, with mean peak gentamicin concentrations of 2.41 μg/ml and 3.92 μg/ml, respectively, observed at 2 h. These concentrations declined in parallel with serum concentrations and were not measurable at 48 h. Urine gentamicin concentration was relatively high, with a mean peak concentration of 424.9 μg/ml at 1 h after drug administration.  相似文献   

CORYNEBACTERIUM EQUI INFECTION IN AN ADULT HORSE   总被引：2，自引：0，他引：2  

M. C. ROBERTS  D. R. HODGSON  W. R. KELLY † 《Australian veterinary journal》1980,56(2):96-97

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HYPERTROPHIC OSTEOPATHY AND DYSGERMINOMA IN A MARE   总被引：2，自引：0，他引：2  

M. W. McLENNAN B.V.Sc.  M.Sc.  W. R. KELLY B.V.Sc.  M.V.Sc.  † 《Australian veterinary journal》1977,53(3):144-146

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Canine parvovirus: a cause of chronic myocardial fibrosis and adolescent congestive heart failure     

R. B. ATWELL  W. R. KELLY 《The Journal of small animal practice》1980,21(11):609-620

Members of three litters of pups infected with canine parvovirus are compared in relation to the time of clinical presentation, clinical, biochemical, electrocardiographical, radiographical and histological findings. Affected pups under 2 months of age showed no clinical signs of myocarditis whereas adolescent pups (over 5 months of age) showed congestive heart failure. Possible reasons for this age difference are discussed.  相似文献   

History of atmospheric lead deposition since 12,370 (14)C yr BP from a peat bog, jura mountains, switzerland   总被引：3，自引：0，他引：3  

W Shotyk  D Weiss  PG Appleby  AK Cheburkin  RFM Gloor  JD Kramers  S Reese  Van Der Knaap WO 《Science (New York, N.Y.)》1998,281(5383):1635-1640

A continuous record of atmospheric lead since 12,370 carbon-14 years before the present (14C yr BP) is preserved in a Swiss peat bog. Enhanced fluxes caused by climate changes reached their maxima 10, 590 (14)C yr BP (Younger Dryas) and 8230 (14)C yr BP. Soil erosion caused by forest clearing and agricultural tillage increased lead deposition after 5320 (14)C yr BP. Increasing lead/scandium and decreasing lead-206/lead-207 beginning 3000 (14)C yr BP indicate the beginning of lead pollution from mining and smelting, and anthropogenic sources have dominated lead emissions ever since. The greatest lead flux (15.7 milligrams per square meter per year in A.D. 1979) was 1570 times the natural, background value (0.01 milligram per square meter per year from 8030 to 5320 (14)C yr BP).  相似文献   

Evaluating resistant brassica trap crops to manage Heterodera schachtii (Schmidt) infestations in eastern England     

Alistair JD Wright  Matthew A Back  Mark Stevens  Debbie L Sparkes 《Pest management science》2019,75(2):438-443

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Optic neuropathy and retinopathy in closantel toxicosis of sheep and goats     

PA GILL  RW COOK  JG BOULTON  WR KELLY  B VANSELOW  LA REDDACLIFF 《Australian veterinary journal》1999,77(4):259-261

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The effect of physical form of a silage on its voluntary consumption and digestibility by sheep     

P. C. THOMAS  N. C. KELLY  M. K. WAIT 《Grass and Forage Science》1976,31(1):19-22

Six castrated male sheep were used in a two-period crossover experiment to investigate the effect of mincing on the voluntary intake and digestibility of a silage. The silage was a high-quality material, containing 68 % digestihle organic matter in the dry matter, prepared from S24 perennial ryegrass cut with a precision chop forage harvester and ensiled with the addition of 2.3 1 t^?1 formic acid as preser vative. The median size of particles in the unprocessed silage was 10–20 mm and in the minced silage 2–3 mm. The intakes of dry matter, organic matter and nitrogen for the minced silage were greater than for the unminced material, and for dry matter and organic matter intakes the differences were signi ficant (P<0.01). Mincing was associated, however, with a depression in the digestibility of all three constituents which offset the increase in intake. The intakes of digestible organic matter were 817 g d^-1 for the minced silage and 729 g d^?1 for the unminced material (P>0.05). Corresponding figures for digestible nitrogen intakes were 208 gd^?1and23.0 gd^?1 (P>005). It is concluded that with high-quality silage diets there is a physical component in the mechanism for the control of voluntary food intake. It is suggested that for sheep, depressions in the digestibility of dietary constituents are unlikely to occur until silages are chopped to a median particle size of 5–10 mm.  相似文献   

The pulmonary circulation as a source of leucocytes and platelets in man     

BIERMAN HR  KELLY KH  KING FW  PETRAKIS NL 《Science (New York, N.Y.)》1951,114(2959):276-277

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Long‐Term‐Release GnRH Agonists Postpone Puberty in Domestic Cats     

A Risso  Y Corrada  C Barbeito  JD Diaz  C Gobello 《Reproduction in domestic animals》2012,47(6):936-938

The aim of this study was to assess the efficacy and safety of deslorelin acetate implants on domestic queen puberty postponement. Thirty, 114.4 ± 12.7 days old, 1.5 ± 0.1 kg prepubertal crossbred female cats were included in this study. The animals were kept under a positive photoperiod and randomly assigned to deslorelin acetate 4.7 mg SC implants (n = 15) or to a non‐treated control group (n = 15). The queens were followed up daily and weighed weekly until puberty. Vaginal cytology was also carried out three times a week. Puberty was diagnosed by the presence of the typical oestrous behaviour and vaginal cytology findings. At puberty, ovariectomy was performed and the gonads grossly described. Age (281.2 ± 21.6 vs 177.8 ± 10.8; p < 0.01) but not weight (2.6 ± 0.1 vs 2.5 ± 0.1; p > 0.1) at puberty differed between the deslorelin and control groups, respectively. One deslorelin‐treated female showed an oestrous response and another showed clinical signs of pyometra after the implants. Deslorelin‐treated ovaries appeared small, while control gonads were normal. It was concluded that long‐term‐release deslorelin, administered at approximately 50% adult body weight, postponed feline puberty without altering growing rate.  相似文献