The Regulation of Aromatase and Androgen Receptor Expression During Gonad Development in Male and Female European Eel     

DS Peñaranda  I Mazzeo  V Gallego  J Hildahl  R Nourizadeh‐Lillabadi  L Pérez  F‐A Weltzien  JF Asturiano 《Reproduction in domestic animals》2014,49(3):512-521

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Paratuberculosis sero-status and milk production,SCC and calving interval in Irish dairy herds     

Hoogendam K  Richardson E  Mee J 《Irish veterinary journal》2009,62(Z4):265-271

The objective of this study was to investigate the impact of paratuberculosis sero-status on milk yield, fat, protein, somatic cell count and calving interval in Irish dairy herds. Serum from all animals over 12 months of age (n = 2,602) in 34 dairy herds was tested for antibodies to Mycobacterium avium subsp. paratuberculosis using an ELISA. Herds were categorised by sero-status into positive, non-negative and negative, where a positive herd contained two or more positive cows, a non-negative herd contained only one positive cow and a negative herd contained no positive cows. Data at animal, parity and herd-level were analysed by multiple regression using general linear models. Positive herds (mean herd size = 129 cows) and non-negative herds (81 cows) were larger than negative herds (72 cows) (P < 0.01). Negative herds had the highest economic breeding index (EBI), while positive herds had the highest estimated breeding value (EBV) for milk yield. There was no significant effect of paratuberculosis sero-status at animal, parity or herd-level on milk yield, milk fat or protein production, somatic cell count score (SCCS) or calving interval. Negative herds tended to have a lower SCCS than positive and nonnegative herds (P = 0.087). This study only examined the effects of paratuberculosis sero-status but did not examine the clinical effects of Johne's disease at the farm or dairy industry levels.  相似文献   

Recent developments in primer design for DNA polymorphism and mRNA profiling in higher plants     

Yang X  Scheffler BE  Weston LA 《Plant methods》2006,2(1):4-10

Primer design is a critical step in the application of PCR-based technologies in gene expression and genetic diversity analysis. As more plant genomes have been sequenced in recent years, the emphasis of primer design strategy has shifted to genome-wide and high-throughput direction. This paper summarizes recent advances in primer design for profiling of DNA polymorphism and mRNA in higher plants, as well as new primer systems developed for animals that can be adapted for plants.  相似文献   

The transcription/migration interface in heart precursors of Ciona intestinalis     

Christiaen L  Davidson B  Kawashima T  Powell W  Nolla H  Vranizan K  Levine M 《Science (New York, N.Y.)》2008,320(5881):1349-1352

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Statement on termination of pregnancy     

Doane WW  Dehaan RL  Weston JA  Kafotis F  Weis JS 《Science (New York, N.Y.)》1972,177(4048):477

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THE PERMANENT SECRETARY'S REPORT ON THE CINCINNATI MEETING. II     

Shull CH  Weston WH  Haskell RJ  Orton CR 《Science (New York, N.Y.)》1924,59(1518):97-100

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Carbon tunneling from a single quantum state     

Zuev PS  Sheridan RS  Albu TV  Truhlar DG  Hrovat DA  Borden WT 《Science (New York, N.Y.)》2003,299(5608):867-870

We observed ring expansion of 1-methylcyclobutylfluorocarbene at 8 kelvin, a reaction that involves carbon tunneling. The measured rate constants were 4.0 x 10(-6) per second in nitrogen and 4 x 10(-5) per second in argon. Calculations indicated that at this temperature the reaction proceeds from a single quantum state of the reactant so that the computed rate constant has achieved a temperature-independent limit. According to calculations, the tunneling contribution to the rate is 152 orders of magnitude greater than the contribution from passage over the barrier. We discuss environmental effects of the solid-state inert-gas matrix on the reaction rate.  相似文献   

CLINICAL AND DIAGNOSTIC IMAGING CHARACTERISTICS OF LATERAL DIGITAL FLEXOR TENDINITIS WITHIN THE TARSAL SHEATH IN FOUR HORSES     

Weston Davis  Christopher J Caniglia  Meghann Lustgarten  Travis Blackwelder  Ian Robertson  W Rich Redding 《Veterinary radiology & ultrasound》2014,55(2):166-173

Lateral digital flexor tendonitis is a rarely reported cause of hind limb lameness in performance horses. The purpose of this retrospective study was to describe clinical and diagnostic imaging findings for a group of horses with lateral digital flexor tendinitis within the tarsal sheath. Equine cases with a diagnosis of lateral digital flexor tendonitis and magnetic resonance imaging (MRI) studies of the affected region were retrieved from North Carolina University's medical record database. Recorded data for included horses were signalment; findings from history, physical examination, lameness examination, and all diagnostic imaging studies; treatment administered; and outcome. Four horses met inclusion criteria. Lameness was mild/moderate in severity and insidious in onset in all patients. Responses to flexion tests were variable. All horses showed positive improvement (70–90%) in lameness after tarsal sheath analgesia. Radiographic, scintigraphic, and ultrasonographic findings were inconclusive. For all horses, MRI characteristics included increased T2, PD, and STIR signal intensity within the lateral digital flexor tendon in the area of the tarsal sheath. Tarsal sheath effusion was slight in three horses, and mild/moderate in one horse. With medical treatment, two horses were sound at 6‐month followup, one horse was sound at 1‐year followup, and one horse had a slight persistent lameness (grade 1/5) at 9‐month followup. Findings supported the use of MRI for diagnosing lateral digital flexor tendonitis within the tarsal sheath in horses. Affected horses may have a good prognosis for return to athletic performance following appropriate medical treatment.  相似文献   

ELASTOGRAPHIC CHARACTERISTICS OF THE METACARPAL TENDONS IN HORSES WITHOUT CLINICAL EVIDENCE OF TENDON INJURY     

Meghann Lustgarten  W. Rich Redding  Raphael Labens  Michel Morgan  Weston Davis  Gabriela S. Seiler 《Veterinary radiology & ultrasound》2014,55(1):92-101

Tendon and ligament injuries are common causes of impaired performance in equine athletes. Gray‐scale ultrasonography is the current standard method for diagnosing and monitoring these injuries, however this modality only provides morphologic information. Elastography is an ultrasound technique that allows detection and measurement of tissue strain, and may provide valuable mechanical information about equine tendon and ligament injuries. The purpose of this study was to determine the feasibility, reproducibility, and repeatability of elastography; and to describe elastographic characteristics of metacarpal tendons in sound horses. Nineteen legs for 17 clinically sound horses without evidence of musculoskeletal pathology were included. Elastographic images of the superficial and deep digital flexor tendons and the branches of the suspensory ligament (tendon of the interosseous muscle) were described quantitatively and qualitatively. There was no statistically significant difference between operators (P = 0.86) nor within operators (P = 0.93). For qualitative assessments, reproducibility (0.46) was moderate and repeatability (0.78) was good. Similar to human Achilles tendons, equine tendons were classified as predominantly hard using elastography. There was no statistically significant difference in stiffness of the flexor tendons (P = 0.96). No significant difference in stiffness was found with altered leg position during standing (P = 0.84) and while nonweight bearing (P = 0.61). The flexor tendons were softer when imaged in longitudinal versus transverse planes (P < 0.01) however, the suspensory branches were not (P = 0.67). Findings supported future clinical application of elastography as a noninvasive “stall‐side” imaging modality for evaluation of the tendons and ligaments of the distal forelimb in horses.  相似文献   

The Forelimb and Hoof Conformation in a Population of Mongolian Horses     

Stuart Gordon  Chris Rogers  Jenny Weston  Charlotte Bolwell  Orgil Doloonjin 《Journal of Equine Veterinary Science》2013

This article describes the lower limb and hoof conformation of a population of semi-feral Mongolian horses living on an open tundra/steppe environment. Data were collected from a convenience sample of 120 Mongolian horses used in the 2011 Mongolian Derby. Digital images of the hooves were obtained, and the lower limb conformation was assessed by four veterinarians involved in the screening of the horses offered for the derby. The horses were predominantly geldings (96%, 100/104), approximately 8.6 ± 2.5 years old, and 137 ± 8 cm at the withers. None of the horses were subjected to routine hoof trimming. Based on a 7-point linear score, lower limb conformation was normal, with a trend (>1 linear score deviation) slightly toward carpal valgus, mildly offset cannon (third metacarpal), and valgus at the matacarpophalangeal joint. Hoof measurements were within the norm for horses of this size. Fetlock valgus was associated with a smaller hoof width:length ratio (P = .016). None of the other hoof measurements were significantly associated with abnormal conformation scores. Overall, few conformation abnormalities were observed, and hoof shape and size was within the normal expected range for horses of this size. The hoof conformation in this population of Mongolian horses represented the natural interaction of the hoof with the environment.  相似文献