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71.
S Lampotang EB Liem D Lizdas S Cantwell JH Modell 《Veterinary anaesthesia and analgesia》2003,30(2):118-119
Gases are transparent and the piping layout in anesthesia machines is not obvious, making it hard to understand anesthesia machine function, potential failure modes, and recovery from faults. We experimented with an approach that simplified the layout of the anesthesia machine piping by removing extraneous details and making gases not only visible, but also color-coded. More than 15 anesthesia machine controls were represented by icons that a user can adjust by clicking on the icon with a pointing device and subsequently observing the effect of his/her intervention on anesthesia machine function in real time. We simulated two anesthesia machine failures and also supported non-English languages and non-US gas color codes. Further, we initiated an experiment in Web philanthropy by deliberately choosing to make the educational module accessible without charge and selected the Web as the preferred medium for dissemination of the Virtual Anesthesia Machine (VAM) viewable at http://www.anest.ufl.edu/vam . Originally designed for use in human anesthesiology, a significant percentage (about 30%) of the 54 000 international visitors, as tracked by an independent third-party Web traffic monitoring service, for the period 9/00–5/02, were from the veterinary field. VAM is being used as part of the curriculum in veterinary programs in the US and overseas and has been well received by the global anesthesia community (human and veterinary). 相似文献
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BPB Rambags AW van Rossem EE Blok E de Graaf-Roelfsema H Kindahl JH van der Kolk TAE Stout 《Reproduction in domestic animals》2008,43(4):422-428
Insulin is a pancreatic hormone that classically regulates carbohydrate and fat metabolism, but also appears to play a role in various reproductive processes. A preliminary study suggested insulin production by day 10 to 18 equine conceptuses. The aim of the present study was to examine the hypothesis that insulin is the conceptus signal responsible for maternal recognition of pregnancy (MRP) in the mare, or otherwise influences reproductive cyclicity during the MRP period. Six Warmblood mares were treated daily during days 7 to 17 after ovulation of two successive oestrous cycles with either (short and intermediate acting) insulin or control saline. Mares were assigned randomly to treatment, and crossed over during the subsequent cycle. Time of ovulation and corpus luteum surface area were determined by serial transrectal ultrasonographic examination of the mares' ovaries, and daily jugular vein blood samples were analysed for progesterone and luteinizing hormone (LH) concentrations. On day 14 of dioestrus, the luteolytic drive was examined by measuring systemic 15-ketodihydroprostaglandin F2 α (PG-metabolite) release in response to oxytocin challenge. In addition, yolk sac fluid recovered from 32 day 10 to 14 equine conceptuses was analysed for insulin concentrations. Insulin administration did not affect luteal size, dioestrus length, the interovulatory interval, or circulating LH concentrations. Insulin administration also failed to suppress oxytocin-induced PGF2 α release, and tended to depress systemic progesterone concentrations. Finally, insulin could not be detected in the yolk sac fluid of day 10 to 14 equine conceptuses by radio-immunoassay. It is concluded that insulin administered daily during days 7 to 17 of dioestrus has little or no effect on reproductive cyclicity in the mare, and is unlikely to be the MRP signal. 相似文献
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Decreased proportion of CD4+ and CD8+ T lymphocytes in peripheral blood likely contributed to susceptibility to Pneumocystis carinii in a foal. Cytological evaluation of bronchoalveolar lavage was required for identification of the pathogen and serial flow-cytometric analysis of peripheral blood lymphocytes documented transient low expression of CD4+ and CD8+ T lymphocytes. Although immunodeficiency is uncommon, it must be included in the differential diagnosis for patients suffering from chronic or opportunistic infections and may provide an indication for immunostimulant therapy. 相似文献
76.
miRNA and piRNA expression profiles of breeder cock testes detected by next‐generation sequencing 下载免费PDF全文
SR Wu W Guo YL Li XC Ren XY Lei XY Li JH Yao XJ Yang 《Reproduction in domestic animals》2017,52(2):203-213
miRNAs are small non‐coding regulatory RNAs that play key roles in diverse biological processes. In this study, we used the Solexa sequencing technique to profile miRNAs in breeder cock testes to illustrate their functions. A total of 663 co‐expressed miRNAs and 3,180 co‐expressed piRNAs were detected in three libraries. Based on Mir‐X? miRNA qRT‐PCR, three miRNAs representing low, medium and high expression levels according to the sequencing results were selected randomly to validate the miRNAs' expression profiles. Results suggested that the miRNA expression profiles data could represent actual miRNA expression levels. Moreover, target genes prediction of the co‐expressed miRNAs and further Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed, which revealed that some candidate miRNAs were involved in the regulation of the spermatogenesis process, spermatozoa function and testicular metabolism. In conclusion, we provided a useful resource for further elucidation of the miRNAs' regulatory role in spermatogenesis, contributing to a preliminary database for functional and molecular mechanistic studies in testicular metabolism, spermatogenesis and other testes functions. 相似文献
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Yongjun ZHENG Shenghui YANG Xingxing LIU Jie WANG Tomas NORTON Jian CHEN Yu TAN 《农业科学与工程前沿(英文版)》2018,5(2):159
The downwash flow field of the multi-rotor unmanned aerial vehicle (UAV), formed by propellers during operation, has a significant influence on the deposition, drift and distribution of droplets as well as the spray width of the UAV for plant protection. To study the general characteristics of the distribution of the downwash airflow and simulate the static wind field of multi-rotor UAVs in hovering state, a 3D full-size physical model of JF01-10 six-rotor plant protection UAV was constructed using SolidWorks. The entire flow field surrounding the UAV and the rotation flow fields around the six rotors were established in UG software. The physical model and flow fields were meshed using unstructured tetrahedral elements in ANSYS software. Finally, the downwash flow field of UAV was simulated. With an increased hovering height, the ground effect was reduced and the minimum current velocity increased initially and then decreased. In addition, the spatial proportion of the turbulence occupied decreased. Furthermore, the appropriate operational hovering height for the JF01-10 is considered to be 3 m. These results can be applied to six-rotor plant protection UAVs employed in pesticide spraying and spray width detection. 相似文献
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