Failure of hyperimmune plasma to prevent pneumonia caused by Rhodococcus equi in foals     

JR HURLEY  AP BEGG† 《Australian veterinary journal》1995,72(11):418-420

SUMMARY A trial was conducted on a Thoroughbred stud to determine whether or not the administration of anti-Rhodococcus equi hyperimmune plasma would reduce the prevalence of R equi pneumonia (rattles) in foals born in the 1992 horse breeding season. Hyperimmune plasma was administered to 34 foals; another 57 foals were untreated. There was no significant difference in the number of transfused foals developing R equi pneumonia compared with the untreated foals. The time required for recovery from pneumonia between the 2 groups was not significantly different.  相似文献   

Duration of Mycoplasma hyopneumoniae Infection in Gnotobiotic Pigs   总被引：3，自引：0，他引：3       下载免费PDF全文

N.R. Underdahl  G.A. Kennedy    A.S. Ramos  JR. 《The Canadian veterinary journal. La revue veterinaire canadienne》1980,21(9):258-261

Sixteen gnotobiotic pigs raised in flexible plastic isolators (four pigs per isolator) were inoculated with a culture of Mycoplasma hyopneumoniae. One pig was killed and underwent necropsy at weekly intervals for the following 16 weeks. Macroscopic lesions were observed in the lungs of 13 of 16 pigs and microscopic lesions were found in 14 of 16 pigs. Mycoplasma hyopneumoniae was cultured from the trachea or lungs from 10 of the 16 pigs. Scanning electron microscope studies showed areas of damage to the cilia, collections, of leucocytes and mucus, and mycoplasma in the trachea as well as the bronchi. These conditions were found in all the pigs seen at necropsy from nine to 16 weeks postinoculation and there was no evidence of noticeable regression or recovery during this 16 week period.  相似文献   

Effect of feeding on plasma antibiotic concentrations in Greyhounds given ampicillin and amoxycillin by mouth     

A. D. J. Watson  JR. Egerton 《The Journal of small animal practice》1977,18(12):779-786

In a cross-over study, six Greyhounds were dosed by mouth with ampicillin and amoxycillin at 20 mg/kg, using three different feeding regimens (no food, canned food prior to dosing, and dry food ad lib ) with each drug. Antibiotic levels in plasma were determined by microbiological assay at intervals after dosing.
Plasma ampicillin concentrations tended to be lower in fed than in starved Greyhounds, but amoxycillin levels were relatively unaffected by feeding. In starved Greyhounds, ampicillin gave higher early levels than amoxycillin.  相似文献   

Eradication of actively spreading ovine footrot     

JR EGERTON 《Australian veterinary journal》1991,68(8):283-283

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Incidence of equine herpesvirus 1 infection in thoroughbred weanlings on two stud farms     

Gilkerson JR  Love DN  Whalley JM 《Australian veterinary journal》2000,78(4):277-278

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Equine herpesvirus 1 (EHV-1) glycoprotein D DNA inoculation in horses with pre-existing EHV-1/EHV-4 antibody     

Ruitenberg KM  Love DN  Gilkerson JR  Wellington JE  Whalley JM 《Veterinary microbiology》2000,76(2):117-127

We have shown previously that equine herpesvirus 1 (EHV-1) glycoprotein D (gD) DNA elicited protective immune responses against EHV-1 challenge in murine respiratory and abortion models of EHV-1 disease. In this study, 20 horses, all with pre-existing antibody to EHV-4 and two with pre-existing antibody to EHV-1, were inoculated intramuscularly with three doses each of 50, 200 or 500microg EHV-1 gD DNA or with 500microg vector DNA. In 8 of 15 horses, inoculation with EHV-1 gD DNA led to elevated gD-specific antibody and nine horses exhibited increased virus neutralising (VN) antibody titres compared to those present when first inoculated. A lack of increase in gC-specific antibody during the 66 weeks of the experiment showed that the increase in gD-specific antibodies was not due to a natural infection with either EHV-1 or EHV-4. The increase in EHV-1 gD-specific antibodies was predominantly an IgGa and IgGb antibody response, similar to the isotype profile reported following natural EHV-1 infection.  相似文献   

Melting Temperature and Partial Melt Chemistry of H2O-Saturated Mantle Peridotite to 11 Gigapascals     

T Kawamoto  JR Holloway 《Science (New York, N.Y.)》1997,276(5310):240-243

The H2O-saturated solidus of a model mantle composition (Kilborne Hole peridotite nodule, KLB-1) was determined to be just above 1000°C from 5 to 11 gigapascals. Given reasonable H2O abundances in Earth's mantle, an H2O-rich fluid could exist only in a region defined by the wet solidus and thermal stability limits of hydrous minerals, at depths between 90 and 330 kilometers. The experimental partial melts monotonously became more mafic with increasing pressure from andesitic composition at 1 gigapascal to more mafic than the starting peridotite at 10 gigapascals. Because the chemistry of the experimental partial melts is similar to that of kimberlites, it is suggested that kimberlites may be derived by low-temperature melting of an H2O-rich mantle at depths of 150 to 300 kilometers.  相似文献   

Universality Classes of Optimal Channel Networks   总被引：1，自引：0，他引：1  

A Maritan  F Colaiori  A Flammini  M Cieplak  JR Banavar 《Science (New York, N.Y.)》1996,272(5264):984-986

Energy minimization of both homogeneous and heterogeneous river networks shows that, over a range of parameter values, there are only three distinct universality classes. The exponents for all three classes of behavior are calculated.  相似文献   

Influence of dietary arginine and glycine content on thyroid function and growth of juvenile rainbow trout, Oncorhynchus mykiss (Walbaum)     

W. W. RILEY  JR  D.A. HIGGS  B.S. DOSANJH  J.G. EALES 《Aquaculture Nutrition》1996,2(4):235-242

Juvenile rainbow trout, held at 12°C on a 12 h light :12 h dark photocycle, were fed a constant ration (1 % of body wt day ^?1) of isonitrogenous and isoenergetic diets that varied in either arginine content (3.6-56.1 g kg^?1 dry matter; experiment 1), or glycine (3.3–118 g kg^?1 dry matter) and alanine (5.0-42.3 g kg^?1 dry matter) content (experiment 2). In experiment 1, the lowest dietary level of arginine depressed growth, feed efficiency, plasma l -thyroxine (T₄) and 3,5,3′-triiodo-l -thyronine (T₃) levels and hepatic T₄ 5’monodeiodinase (5'D) activity responsible for T₄-to-T₃ conversion. Over the dietary range of 7.1–56.1 g arginine kg^?1, there was no change in 5'D activity, despite an arginine stimulation of growth. The optimum level of arginine for growth was within the range of 14.1–28.1 g kg^?1 of the diet or 32–63 g kg^?1 of dietary protein. In experiment 2, an increase in dietary glycine level, at the expense of glutamic acid, increased 5'D activity without attendant elevation of the plasma T₃ level. The latter finding suggests that glycine also induced a compensatory increase in T₃ degradation rate. This may explain why the glycine-induced increase in 5'D activity was unaccompanied by any changes in growth indices. Alteration of dietary alanine content did not affect growth or thyroid function. We conclude that of the various dietary amino acids tested, only glycine led to a progressive stimulation of hepatic T₄ 5'D activity. However, because glycine likely enhanced T₃ degradation, no increases in plasma T₃ or growth indices were found. Glycine may serve as an advance signal that activates thyroid function immediately preceding or coincident with energy and nutrient (especially protein) intake. This, in turn, may improve the efficiency of nutrient absorption and/or post-absorptive anabolic events.  相似文献   

Action of selected antibiotics on four common bacteria associated with diseases of fish     

K. E. NUSBAUM  E. B. SHOTTS  JR 《Journal of fish diseases》1981,4(5):397-404

Abstract. Four bacteria commonly associated with diseases of fish ( Aeromonas hydrophila complex, Aeromonas salmonicida, Flexibacter columnaris -like organisms and Pseudomonas fluorescens ) were evaluated in a serial dilution system for susceptibility to four antibiotics commonly used in the treatment of bacterial fish diseases (chloramphenicol, erythromycin, furpyrinol and oxytetracycline). Findings were expressed as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Furpyrinol was found to have the lowest MIC and MBC against A. hydrophila complex, A. salmonicida and F. columnaris-like organisms. MIC and MBC's for oxytetracycline were complicated by the presenceof R-plasmids, but were less than 4.0 mcg/ml for those without plasmids. Pseudomonas fluorescens was susceptible only to oxytetracycline. MIC for all groups of organisms using chloramphenicol was generally less than 16.0 mcg/ml. Susceptibility to erythromycin by these groups of organisms was greater than 16 mcg/ml.  相似文献