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71.
72.
Duration of Mycoplasma hyopneumoniae Infection in Gnotobiotic Pigs   总被引:3,自引:0,他引:3       下载免费PDF全文
Sixteen gnotobiotic pigs raised in flexible plastic isolators (four pigs per isolator) were inoculated with a culture of Mycoplasma hyopneumoniae. One pig was killed and underwent necropsy at weekly intervals for the following 16 weeks. Macroscopic lesions were observed in the lungs of 13 of 16 pigs and microscopic lesions were found in 14 of 16 pigs. Mycoplasma hyopneumoniae was cultured from the trachea or lungs from 10 of the 16 pigs. Scanning electron microscope studies showed areas of damage to the cilia, collections, of leucocytes and mucus, and mycoplasma in the trachea as well as the bronchi. These conditions were found in all the pigs seen at necropsy from nine to 16 weeks postinoculation and there was no evidence of noticeable regression or recovery during this 16 week period.  相似文献   
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In a cross-over study, six Greyhounds were dosed by mouth with ampicillin and amoxycillin at 20 mg/kg, using three different feeding regimens (no food, canned food prior to dosing, and dry food ad lib ) with each drug. Antibiotic levels in plasma were determined by microbiological assay at intervals after dosing.
Plasma ampicillin concentrations tended to be lower in fed than in starved Greyhounds, but amoxycillin levels were relatively unaffected by feeding. In starved Greyhounds, ampicillin gave higher early levels than amoxycillin.  相似文献   
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The H2O-saturated solidus of a model mantle composition (Kilborne Hole peridotite nodule, KLB-1) was determined to be just above 1000°C from 5 to 11 gigapascals. Given reasonable H2O abundances in Earth's mantle, an H2O-rich fluid could exist only in a region defined by the wet solidus and thermal stability limits of hydrous minerals, at depths between 90 and 330 kilometers. The experimental partial melts monotonously became more mafic with increasing pressure from andesitic composition at 1 gigapascal to more mafic than the starting peridotite at 10 gigapascals. Because the chemistry of the experimental partial melts is similar to that of kimberlites, it is suggested that kimberlites may be derived by low-temperature melting of an H2O-rich mantle at depths of 150 to 300 kilometers.  相似文献   
79.
Universality Classes of Optimal Channel Networks   总被引:1,自引:0,他引:1  
Energy minimization of both homogeneous and heterogeneous river networks shows that, over a range of parameter values, there are only three distinct universality classes. The exponents for all three classes of behavior are calculated.  相似文献   
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Juvenile rainbow trout, held at 12°C on a 12 h light :12 h dark photocycle, were fed a constant ration (1 % of body wt day ?1) of isonitrogenous and isoenergetic diets that varied in either arginine content (3.6-56.1 g kg?1 dry matter; experiment 1), or glycine (3.3–118 g kg?1 dry matter) and alanine (5.0-42.3 g kg?1 dry matter) content (experiment 2). In experiment 1, the lowest dietary level of arginine depressed growth, feed efficiency, plasma l -thyroxine (T4) and 3,5,3′-triiodo-l -thyronine (T3) levels and hepatic T4 5’monodeiodinase (5'D) activity responsible for T4-to-T3 conversion. Over the dietary range of 7.1–56.1 g arginine kg?1, there was no change in 5'D activity, despite an arginine stimulation of growth. The optimum level of arginine for growth was within the range of 14.1–28.1 g kg?1 of the diet or 32–63 g kg?1 of dietary protein. In experiment 2, an increase in dietary glycine level, at the expense of glutamic acid, increased 5'D activity without attendant elevation of the plasma T3 level. The latter finding suggests that glycine also induced a compensatory increase in T3 degradation rate. This may explain why the glycine-induced increase in 5'D activity was unaccompanied by any changes in growth indices. Alteration of dietary alanine content did not affect growth or thyroid function. We conclude that of the various dietary amino acids tested, only glycine led to a progressive stimulation of hepatic T4 5'D activity. However, because glycine likely enhanced T3 degradation, no increases in plasma T3 or growth indices were found. Glycine may serve as an advance signal that activates thyroid function immediately preceding or coincident with energy and nutrient (especially protein) intake. This, in turn, may improve the efficiency of nutrient absorption and/or post-absorptive anabolic events.  相似文献   
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