Vaginourethroplasty for Treatment of Urethral Obstruction in the Bitch   总被引：1，自引：0，他引：1  

R. N. WHITE BSc  BVetMed  CertVA  Diplomate ECVS    J. V. DAVIES BVetMed  PhD  DVR  Diplomate ECVS  S. P. GREGORY BVetMed  PhD  DVR 《Veterinary surgery : VS》1996,25(6):503-510

Vaginourethroplasty was performed in six bitches with infiltrative, obstructive urethral disease. The initial clinical signs included dysuria, hematuria, pollakiuria, and stranguria. Diagnosis was based on the clinical signs, plain radiography and contrast vagino-urethrogram examination, and urethral biopsy. Five dogs were diagnosed as having urethral neoplasia; the sixth dog had granulomatous urethritis. In all six dogs, up to 50% of the urethra and the urethral tubercle were resected to ensure adequate surgical margins. One dog was euthanatized 4 months after surgery for recurrence of a transitional cell carcinoma at the surgical site. Long-term resolution of the problem (minimum of 12 months) was achieved in the other five dogs. The frequency of serious complications, including urinary incontinence and ascending lower urinary tract infections, was low.  相似文献   

Evaluation of auditory evoked potentials to predict depth of anaesthesia during fentanyl/fluanisone−midazolam anaesthesia in rats     

LM Antunes MSc  DVM    JV Roughan BSc  PhD  & PA Flecknell MA  Vet MB  PhD  DLAS  Dip ECVA 《Veterinary anaesthesia and analgesia》2001,28(4):196-203

Objectives To assess a method for monitoring depth of anaesthesia using components of middle latency auditory evoked potential (AEP) waveforms during anaesthesia with fentanyl/fluanisone and midazolam. Study design Prospective observational study. Animals Five female Wistar rats weighing between 210 and 250 g. Methods Implanted electrodes were used to record AEPs in animals receiving five doses of anaesthetic. Recordings were made at 5 minutes post‐injection (deep anaesthesia; no pedal withdrawal response, PWR) and then at 25 minutes (light anaesthesia; strong PWR). Responses showed five characteristic peaks occurring at 11, 14, 23, 42 and 68 ms that were measured for latency of occurrence and peak amplitude. Results Auditory evoked potential peaks P14, N23 and P42 were increased significantly in latency with successive anaesthetic injections [avg. F(1,4) = 12.53, p < 0.001; avg. F(1,4) = 10.6, p < 0.001; avg. F(1,4) = 3.9, p = 0.02, respectively]. Peak N23 showed a significant reduction in latency during the 20 minute recovery period following both the first and second anaesthetic injections (t(3) = 7.52, p = 0.005; t(4) = 5.17, p = 0.007, respectively). Peak P42 occurred significantly earlier 20 minutes following the second anaesthetic injection (t(4) = 4.75, p = 0.009). The mean overall depth of anaesthesia assessed using PWR scores was significantly correlated with the mean latency of peak N23, such that as the strength of PWR increased, N23 occurred significantly earlier (r = ?0.99, p = 0.01). The amplitude difference between peaks N23 and P42 increased after the second and third drug administrations [avg. F(1,4) = 10.65, p = 0.031 and avg. F(1,4) = 11.24, p = 0.028, respectively]. Conclusion The characteristics of these peaks, and in particular latency of peak N23, may provide a useful tool for assessing depth of anaesthesia produced by this, and possibly other anaesthetic agents.  相似文献   

Letter to the Editor     

F. G. Startup Ph.D.  BSc.  M.R.C.V.S. 《The Journal of small animal practice》1966,7(7):505-505

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Effect of Intraperitoneal PERIDAN™ Concentrate Adhesion Reduction Device on Clinical Findings,Infection, and Tissue Healing in an Adult Horse Jejunojejunostomy Model     

Samantha Morello DVM  Diplomate ACVS  Julie Engiles VMD  DACVP  JoAnn Slack DVM  Aaron Crack BSc  Christopher M. K. Springate BSc  PhD 《Veterinary surgery : VS》2012,41(5):568-581

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Surgical Treatment of an Intracranial Epidermoid Cyst in a Dog     

Steven De Decker DVM  PhD  Emma Davies DVM  Diplomate ECVN  Livia Benigni DVM  Diplomate ECVDI  Helen Wilson BVSc  Ludovic Pelligand DVM  PhD  Diplomate ECVAA  Emma L. Rayner BSc  BVetMed  FRCPath  MRCVS  Nadia Shihab MA  VetMB  Diplomate ECVN  Holger A. Volk DVM  PhD  Diplomate ECVN 《Veterinary surgery : VS》2012,41(6):766-771

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A Biomechanical Comparison of Three Hybrid Linear‐Circular External Fixator Constructs     

Caleb C Hudson DVM  MS  Daniel D Lewis DVM  Diplomate ACVS  Alan R Cross DVM  Diplomate ACVS  Nicholas J Dunbar BSc  MaryBeth Horodyski EdD  ATC  LAT  Scott A Banks PhD  MS  Antonio Pozzi DMV  MS  Diplomate ACVS 《Veterinary surgery : VS》2012,41(8):954-965

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Exogenous L‐lactate clearance in adult horses     

Pedro De Pedro DVM  Maureen A. McMichael DVM  DACVECC  Levent Dirikolu DVM  PhD  Kara M. Lascola DVM  MS  DACVIM  Stuart C. Clark‐Price DVM  MS  DACVIM  DACVA  Raymond C. Boston BSc  MSc  PhD 《Journal of Veterinary Emergency and Critical Care》2012,22(5):564-572

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Assessment of ketamine/medetomidine anaesthesia in the New Zealand White rabbit     

P Hedenqvist DVM  Jv Roughan BSc PhD    He Orr BVM&S Cert LAS    L M Antunes MSc DVM 《Veterinary anaesthesia and analgesia》2001,28(1):18-25

Objective To compare the characteristics of anaesthesia induced with four dose combinations of ketamine/medetomidine. Design Prospective randomized study. Animals Five female New Zealand White (NZW) rabbits of approximately 2.3 kg. Methods Rabbits were given one of four drug combinations (25/0.25; 15/0.5; 15/0.25 and 10/0.5 mg kg^?1 IM) on four successive occasions with a four day interval. Response to injection and then arterial blood gas and cardiovascular parameters were recorded at predetermined time points. Toe and ear pinch reflexes gave measures of total duration of surgical anaesthesia and total sleep time. Analyses used repeated measures analysis of variance. Results Induction was smooth with little reaction to injection and intubation achieved easily. Two combinations (15/0.25, 10/0.5) produced moderate hypoxaemia (mean pO₂ < 8.0 kPa) and two (25/0.25, 15/0.5) very marked hypoxaemia (mean pO₂ < 5.3 kPa). This was reversed within 15 minutes of oxygen administration and all rabbits recovered uneventfully. Heart rates fell in all cases, with only minimal effects on arterial blood pressure and no cardiac arrhythmias. Mean duration of surgical anaesthesia was significantly longer for dose groups 25/0.25 (57 ± 12 minutes) and 15/0.5 (59 ± 17 minutes, p = 0.01) compared to dose group 15/0.25 (27 ± 8 minutes). Only three animals in the 10/0.5 mg kg^?1 group achieved surgical anaesthesia. Mean duration of loss of the ear pinch reflex was similar between doses, being, respectively, 64 ± 13, 81 ± 7, 60 ± 22 and 62 ± 24 minutes. Sleep time was significantly longer for the 15/0.5 dose (112 ± 10 minutes) compared to 15/0.25 (86 ± 22 minutes, p = 0.04). Sleep times for the 25/0.25 and 10/0.5 mg kg^?1 doses were, respectively, 103 ± 23 and 108 ± 12 minutes. Conclusions Ketamine/medetomidine reliably produces smooth induction and recovery in the NZW rabbit, but due to the degree of hypoxaemia produced, should only be used with simultaneous provision of oxygen. Clinical relevance Currently recommended dose rates of ketamine/medetomidine for minor procedures such as ovariohysterectomy in rabbits (25 mg/0.5 mg kg^?1) are unnecessarily high; a dose of 15/0.25 mg kg^?1 should be adequate for 15–30 minutes of surgical anaesthesia.  相似文献   

Use of an ex vivo canine ventral slot model to test the efficacy of a piezoelectric cutting tool for decompressive spinal surgery     

Miguel A. Solano DVM  Noel Fitzpatrick DUniv MVB  CertSAO  CertVR  Jelena Jovanovik PGDip  BSc 《Veterinary surgery : VS》2013,42(7):832-839

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Effects of α-tocopherol and Ascorbic Acid on Equine Semen Quality after Cryopreservation     

Joanna Sousa Vasconcelos Franco  António ChaveiroAna Góis  BSc  Fernando Moreira da Silva  PhD 《Journal of Equine Veterinary Science》2013

This study investigated the effects of ascorbic acid and α-tocopherol supplementation on semen quality parameters of equine thawed-frozen semen. Semen was divided in seven different treatments in a final concentration of 100 × 10⁶ sperm/mL by using Gent extender containing no supplements (control) and the following supplements with three different concentrations: α-tocopherol (0.5, 1, and 2 mM) and ascorbic acid (0.45, 0.9, and 1.8 g/L). After thawing, all samples were maintained at 37°C, while analyses were performed at 0, 60, and 120 minutes. Evaluation of viability and acrosome status (using Pisum sativum agglutinin conjugated to fluorescein isothiocyanate and propidium iodide), mitochondrial membrane potential (5,5′,6,6′-tetrachloro-1,1′,3,3′tetraethylbenzimidazolyl carbocyanine iodine [JC-1]), membrane lipid peroxidation (LPO; C₁₁-BODIPY^581/591), and stability of the plasmatic membrane (merocyanine 540 and Yo-Pro-1) of each sample was determined by flow cytometry. Relative to the control group, supplementation with α-tocopherol improved (P ≤ .05) postthaw membrane LPO, yet the higher concentrations of ascorbic acid (0.9 and 1.8 g/L, respectively) showed a negative effect on membrane LPO. Neither antioxidant significantly increased (P > .05) the acrosome integrity and mitochondrial membrane potential of frozen-thawed spermatozoa, although supplementation with α-tocopherol and ascorbic acid (0.9 and 1.8 g/L, respectively) had a positive effect on membrane integrity and stability (P ≤ .05). For all semen parameters, the lower concentration of ascorbic acid (0.45 g/L) did not show significant differences (P > .05) compared with the control. In conclusion, α-tocopherol seems to be an efficient antioxidant for reducing the oxidative stress provoked by cryopreservation, decreasing lipid peroxidation on equine spermatozoa.  相似文献