A comparison of haemoglobins from the adult and newborn dog     

C K Lee  G V Odell  I L Anderson  F P Eliot  E W Jones 《Research in veterinary science》1973,15(3):333-337

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A quantitative analysis of the literature concerning the restricted feeding of growing pullets   总被引：2，自引：2，他引：0  

P. J. W. Lee  A. L. Gulliver  T. R. Morris 《British poultry science》1971,12(4):413-437

The sexual maturity of growing pullets can be retarded either by restricting calorie intake or by feeding a diet deficient in one or more essential amino acids, Several methods have been proposed for achieving either of these objectives. In this review the methods have been classified as (a) limiting the birds’ time of access to food, (b) quantitative food restriction, (c) the use of low energy diets and (d) dietary protein restriction.

Food restriction by limiting the time of access to food has given inconsistent results and is an unsatisfactory technique. Birds quickly learn to eat normal quantities of food in a very short space of time.

Quantitative food restriction has been widely used in experiments and is usually applied from about 6 to about 20 weeks of age. The available evidence enables relationships to be established between the degree of food restriction and subsequent body weight and sexual maturity. The effect of rearing treatment on mortality and rate of lay is also examined.

The ad libitum feeding of a low‐energy growing diet has always resulted in greater rearing food costs. This is because moderate reductions in energy content of the diet are offset by higher food intake. Diets sufficiently low in energy to cause a reduction in calorie intake will involve the purchase and handling of very large proportions of non‐nutritive material.

The use of protein‐deficient diets during the growing period, or from one day of age, offers a suitable means of delaying sexual maturity. The effects of such a treatment are apparently very similar to those of restricted feeding, but there is a lack of suitable comparisons of the alternative methods.  相似文献   

Radiographic examination of localised and diffuse tissue swellings in the mandibular and pharyngeal area     

R Lee 《The Veterinary clinics of North America》1974,4(4):723-740

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Preputial eversion in the bull: relationship to penile movement     

S E Long  P G Hignett  R Lee 《The Veterinary record》1970,86(7):192-194

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Chronology of development of serum antispirochete antibody in swine experimentally exposed to swine dysentery: preliminary report.     

C H Lee  L D Olson 《American journal of veterinary research》1977,38(4):539-540

By using an indirect fluorescent antibody test (with immunofluorescence of large spirochetes as positive), serum antispirochete antibodies were detected initially at 4 weeks after onset of diarrhea in swine exposed to infective swine dysentery inoculum. Antibodies continued to be present in serum of swine tested 5 months after onset of diarrhea.  相似文献   

Use of hyperimmune serum, vaccination, and certain management procedures for control of pseudorabies in swine     

F S Hsu  R C Lee 《Journal of the American Veterinary Medical Association》1984,184(12):1463-1466

A program involving use of hyperimmune serum, vaccination, and certain management procedures for the control of pseudorabies was evaluated on several farms on which the disease was enzootic. Neonatal mortality and reproductive failures on farms utilizing the program were compared with death losses and reproductive failures on farms not utilizing the program. The reduction in preweaning mortality and reproductive failures between the treated and nontreated groups were 42.1% and 39.6%, respectively.  相似文献   

Inhibition of juvenile hormone biosynthesis in the tobacco hornworm, Manduca sexta, by a bisthiolcarbamate juvenoid and related compounds     

Steven J. Kramer  Leslie W. Tsai  Shy-Fuh Lee  Julius J. Menn 《Pesticide biochemistry and physiology》1982,17(2):134-141

Biosynthesis of juvenile hormone in the tobacco hornworm, Manduca sexta, is inhibited by the bisthiolcarbamate juvenoid N-ethyl-1,2-bis(isobutylthiolcarbamoyl)ethane both in vitro and in vivo. In vitro an extremely steep dose-response curve was obtained with an ID₅₀ value of 6 × 10^?6M. However, in vivo topical treatment with the compound resulted in mild JH antagonistic symptoms, suggesting rapid metabolism of the compound. In agreement with results from metabolic studies performed on plants and in mammals, sulfoxidation of the thiocarbamate S-(4-chlorobenzyl)N,N-diethylthiocarbamate resulted in an enhanced inhibitory effect on JH biosynthesis in vitro. This suggests that the corresponding thiocarbamate sulfoxides may act as intermediates in carbomylating critical thiol sites important in the terpenoid biosynthesis pathway. Furthermore, this study shows that these prototype compounds are interesting tools for further investigation of chemical inhibition of JH biosynthesis in insects.  相似文献   

The bovine neutrophil: Structure and function in blood and milk   总被引：1，自引：0，他引：1  

Paape MJ  Bannerman DD  Zhao X  Lee JW 《Veterinary research》2003,34(5):597-627

Migration of polymorphonuclear neutrophil leukocytes (PMN) into the mammary gland provide the first line of defense against invading mastitis pathogens. Bacteria release potent toxins that activate white blood cells and epithelial cells in the mammary gland to secrete cytokines that recruit PMN that function as phagocytes at the site of infection. While freshly migrated PMN are active phagocytes, continued exposure of PMN to inhibitory factors in milk such as fat globules and casein, leads to altered PMN morphology and reduced phagocytosis. In the course of phagocytosing and destroying invading pathogens, PMN release chemicals that not only kill the pathogens but that also cause injury to the delicate lining of the mammary gland. This will result in permanent scarring and reduced numbers of milk secretory cells. The life span of PMN is limited by the onset of apoptosis. To minimize damage to mammary tissue, PMN undergo a specialized process of programmed cell death known as apoptosis. Macrophages quickly engulf and phagocytose apoptotic PMN, thereby minimizing the release of PMN granular contents that are damaging to tissue. The PMN possess an array of cell surface receptors that allow them to adhere and migrate through endothelium and to recognize and phagocytose bacteria. One receptor found on phagocytes that is receiving considerable attention in the control of infections by Gram-negative bacteria is CD14. Binding of lipopolysaccharide (LPS) to membrane bound CD14 causes release of tumor necrosis factor-alpha and sepsis. Binding of LPS to soluble CD14 shed from CD14-bearing cells results in neutralization of LPS and rapid recruitment of PMN to the site of infection. Recent advances in the fields of genomics and proteomics should greatly enhance our understanding of the PMN role in controlling intramammary infections in ruminants. Further, manipulation of PMN, through either recombinant proteins such as soluble CD14 that enhance PMN response or agents that mediate PMN apoptosis, may serve as novel therapeutics for the treatment of mastitis.  相似文献   

Flow cytometric assessment of ethylene glycol monoethyl ether on spermatogenesis in rats   总被引：1，自引：0，他引：1  

Yoon CY  Hong CM  Cho YY  Chung YH  Min HK  Yun YW  Lee BJ  Yang KH  Lee YS  Kim CK 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(2):207-212

The effects of ethylene glycol monoethyl ether (EGEE) on testicular cell populations in rats were investigated by a flow cytometric method. Rats were administered by gavage with EGEE at the various doses of 0 (saline alone), 100, 200, 400, and 800 mg/kg body weight/day for 4 weeks. The treatment of EGEE caused decreases in the weight of testis and epididymis and in the number of testicular cells. Histopathologically, exfoliation of germ cells into the tubular lumen was observed at the doses of above 200 mg/kg. The treatment of EGEE at the dose of 400 mg/kg caused moderate testicular degeneration. A significant depletion of haploid cells and a disproportionate ratio of diploid and tetraploid cells were observed as determined by flow cytometric analysis. These results indicate that the toxic effect of EGEE on the male reproductive system may be strongly associated with the disproportion of testicular germ cells.  相似文献   

Effect of intravenous mannitol upon the resistive index in complete unilateral renal obstruction in dogs     

Choi H  Won S  Chung W  Lee K  Chang D  Lee H  Eom K  Lee Y  Yoon J 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2003,17(2):158-162

Some studies have shown that relative to baseline, the renal resistive index (RI) remains unchanged in nonobstructed kidneys and increases in obstructed kidneys after administration of furosemide. To our knowledge, the effect of mannitol administration on the renal RI of dogs has not been reported. We evaluated the renal RI in 16 kidneys in 8 young adult dogs after administration of mannitol. The mean RI decreased significantly from baseline (P < .01). Additionally, left complete ureteral obstruction wasinduced in 5 dogs. Evaluation by Doppler ultrasonography was performed for 5 days. On the 5th day, Doppler examination was repeated at 30 and 60 minutes after administration of mannitol to obstructed dogs. After induction of left ureteral obstruction, the RI of the left kidney increased significantly over 5 consecutive days. Administration of mannitol decreased the RI in the nonobstructed contralateral kidneys, and thus the RI difference between obstructed and nonobstructed kidneys was increased above normal (P < .001). In conclusion, administration of mannitol may be useful as another diuretic agent to identify unilateral ureteral obstruction on Doppler sonographic examination.  相似文献