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Plant resistance proteins detect the presence of specific pathogen effectors and initiate effector-triggered immunity. Few immune regulators downstream of resistance proteins have been identified, none of which are known virulence targets of effectors. We show that Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1), a positive regulator of basal resistance and of effector-triggered immunity specifically mediated by Toll-interleukin-1 receptor-nucleotide binding-leucine-rich repeat (TIR-NB-LRR) resistance proteins, forms protein complexes with the TIR-NB-LRR disease resistance proteins RPS4 and RPS6 and with the negative immune regulator SRFR1 at a cytoplasmic membrane. Further, the cognate bacterial effectors AvrRps4 and HopA1 disrupt these EDS1 complexes. Tight association of EDS1 with TIR-NB-LRR-mediated immunity may therefore derive mainly from being guarded by TIR-NB-LRR proteins, and activation of this branch of effector-triggered immunity may directly connect to the basal resistance signaling pathway via EDS1.  相似文献   
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A simple and effective method for impregnation of p-aramid (Kevlar®) fabric with shear thickening fluid (STF) has been developed in this research. Kevlar fabric was impregnated with STF in two stages in a sequential manner. Three levels of pressure (0.5, 1 and 2 bar) were used in each stage of impregnation. It was observed that impact energy absorption by Kevlar fabrics, impregnated with STF in this newly developed method, increased significantly as compared to untreated Kevlar fabrics and Kevlar fabrics treated with STF in conventional way (single step impregnation). Better results were obtained when the first impregnation pressure was higher than that of the second, even with same combination of pressures. Such fabrics also showed a much higher STF add-on (~18 %) as compared to that of fabrics impregnated in single step (3-5 %). Low velocity ballistic tests also confirmed the advantages of the new method as sequentially impregnated fabric showed 124.8 % and 24.4 % increase in impact energy absorption compared to untreated and STF impregnated Kevlar fabrics in single step, respectively.  相似文献   
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