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31.
Nicole S. Yang Eric G. Johnson Carrie A. Palm Jenna H. Burton Robert B. Rebhun Michael S. Kent William T.N. Culp 《Veterinary radiology & ultrasound》2023,64(1):105-112
Magnetic resonance imaging (MRI) has been used to evaluate dogs with suspected prostatic neoplasia, however, published studies describing MRI characteristics of canine prostatic neoplasia are currently lacking. The aims of the current retrospective case series study were to describe MRI findings of the pelvic region in dogs with a histopathologic or cytologic diagnosis of prostatic neoplasia. Retrospective analysis of these images was then performed by a board-certified veterinary radiologist for shared imaging characteristics. The most consistent characteristics were heterogeneous hyperintensity of the tumor on T2-weighted images (10/10) and short tau inversion recovery images (10/10), prostatic capsular margin distortion by the tumor (10/10), cavitations (10/10), complete effacement of the prostatic architecture (9/10), neurovascular bundle (NVB) compression or invasion (9/10), heterogeneous isointensity of the tumor on T1-weighted images (9/10), and strong contrast enhancement of the tumor (8/10). Additional features included an overlying pattern of distorted radiating striations (7/10), regional lymphadenomegaly (5/10), mineralization within the mass (5/10), urinary bladder trigone involvement (6/10), and post-prostatic urethral involvement (7/10). These findings supported the use of MRI as an adjunct imaging modality for diagnosis and therapeutic planning of prostatic neoplasia and including prostatic neoplasia as a likely differential diagnosis for dogs with these MRI characteristics. 相似文献
32.
Lucie Noall Suhwon Lee Jenna H. Burton Taya M. Marquardt Justin Cermak Lori A. Thombs Anita M. Rogic Jeffrey N. Bryan Shirley Chu 《Veterinary and comparative oncology》2023,21(3):509-519
Feline oral squamous cell carcinoma (FOSCC) is an aggressive cancer in domestic cats that has no effective treatment option when advanced. Preventative or early diagnostic measures are thus crucial. FOSCC is also a model for human head and neck SCC (HNSCC); strong risk factors in HNSCC include exposure to alcohol, tobacco, areca nut, and high-risk human papillomavirus. Previous studies have identified flea collar and tobacco smoke exposure, feeding canned tuna, canned cat food and cat foods with chemical additives, living in a rural environment, and having outdoor access as risk factors for FOSCC but there was no overlap in the risk factors between studies. In our study, risks for FOSCC were evaluated in an online epidemiologic survey study in 67 cats with FOSCC and 129 control cats. Clumping clay cat litter and flea collar use were significant risk factors for FOSCC on multiple logistic regression with odds ratios of 1.66 (95% CI 1.20–2.30) and 4.48 (95% CI 1.46–13.75) respectively. Crystalline silica is a carcinogen that may be present in all clay cat litters and tetrachlorvinphos is a carcinogen that is present in the most commonly used flea collars in our study. We recommend further investigation into the association between FOSCC and clay-based litter and/or flea collars containing tetrachlorvinphos. 相似文献
33.
Louise Katherine BARTOLAC Jenna Louise LOWE George KOUSTAS Cecilia SJ?BLOM Christopher Gerald GRUPEN 《The Journal of reproduction and development》2015,61(6):525-531
The aim of this study was to determine the optimum conditions for vitrifying in vitro
produced day 7 porcine embryos using different vitrification devices and blastocoele collapse methods. Firstly
embryos were collapsed by micro-pipetting, needle puncture and sucrose with and without conducting
vitrification. In the next experiment, non-collapsed embryos were vitrified in an open device using either
superfine open-pulled straws (SOPS) or the CryoLoopTM system, or vitrified in a closed device using
either the CryoTipTM or Cryo BioTM’s high security vitrification system (HSV). The
post-thaw survival of embryos vitrified in the open devices did not differ significantly (SOPS: 37.3%;
CryoLoopTM: 37.3%) nor did the post-thaw survival of embryos vitrified in the closed devices
(CryoTip™: 38.5%; HSV: 42.5%). The re-expansion rate of embryos that were collapsed via micro-pipetting
(76.0%) did not differ from those that were punctured (75.0%) or collapsed via sucrose (79.6%) when
vitrification was not performed. However, embryos collapsed via sucrose solutions (24.5%) and needle puncture
(16.0%) prior to vitrification were significantly less likely to survive vitrification than the control
(non-collapsed) embryos (53.6%, P < 0.05). The findings show that both open and closed vitrification
devices were equally effective for the vitrification of porcine blastocysts. Collapsing blastocysts prior to
vitrification did not improve survival, which is inconsistent with the findings of studies in other species.
This may be due to the extremely sensitive nature of porcine embryos, and/or the invasiveness of the
collapsing procedures. 相似文献
34.
Ward CR Achenbach SE Peterson ME Drobatz KJ Holt D 《American journal of veterinary research》2005,66(9):1478-1482
OBJECTIVE: To identify within guanosine triphosphate-binding proteins (G proteins) the subset of inhibitory G proteins (G) that have decreased expression in adenomatous thyroid glands obtained from hyperthyroid cats. SAMPLE POPULATION: Adenomatous thyroid glands obtained from 5 hyperthyroid cats and normal thyroid glands obtained from 3 age-matched euthyroid cats. PROCEDURE: Expression of G(i1), G(i2), and G(i3) in enriched membrane preparations from thyroid glands was quantified by use of immunoblotting with G(i) subtype-specific antibodies. RESULTS: Expression of G(i2) was significantly decreased in tissues of hyperthyroid glands, compared with expression in normal thyroid tissue. Expression of G(i1) and G(i3) was not significantly different between normal thyroid tissues and tissues from hyperthyroid glands. CONCLUSIONS AND CLINICAL RELEVANCE: A decrease in G(i2) expression decreases inhibition of adenylyl cyclase and allows a relative increase in stimulatory G protein expression. This results in increased amounts of cAMP and subsequent unregulated mitogenesis and hormone production in hyperthyroid cells. Decreased G(i2) expression may explain excessive growth and function of the thyroid gland in cats with hyperthyroidism. 相似文献
35.
Maurizio Longo Florence Thierry Kevin Eatwell Tobias Schwarz Jorge del Pozo Jenna Richardson 《Veterinary radiology & ultrasound》2018,59(5):E56-E60
A 9‐month‐old neutered male rabbit was referred for lethargy, anorexia, and gastrointestinal stasis. Routine hematology, serum biochemistry, and diagnostic imaging were performed. Computed tomography revealed a wall thickening of the sacculus rotundus and appendix, which was further confirmed on abdominal ultrasound. Full thickness biopsies were collected with histopathology diagnosing a chronic multifocal heterophilic granulomatous sacculitis and appendicitis. The patient was treated medically and at 6 weeks follow‐up, clinical signs and intestinal changes had completely regressed. Inflammation of the sacculus rotundus and appendix should be considered as a cause of gastrointestinal stasis in rabbits. 相似文献
36.
Effect of different penetrating and non‐penetrating cryoprotectants and media temperature on the cryosurvival of vitrified in vitro produced porcine blastocysts 
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下载免费PDF全文 Louise Katherine Bartolac Jenna Louise Lowe George Koustas Christopher Gerald Grupen Cecilia Sjöblom 《Animal Science Journal》2018,89(9):1230-1239
The aim of this study was to determine the most efficient vitrification protocol for the cryopreservation of day 7 in vitro produced (IVP) porcine blastocysts. The post‐warm survival rate of blastocysts vitrified in control (17% dimethyl sulfoxide + 17% ethylene glycol [EG] + 0.4 mol/L sucrose) and commercial media did not differ, nor did the post‐warm survival rate of blastocysts vitrified in medium containing 1,2‐propandiol in place of EG. However, vitrifying embryos in EG alone decreased the cryosurvival rate (55.6% and 33.6%, respectively, p < .05). Furthermore, the post‐warm survival rates of blastocysts vitrified with either trehalose or sucrose as the non‐penetrating cryoprotectant did not differ. There was also no significant difference in post‐warm survival of blastocysts vitrified in control (38°C) media and room temperature (22°C) media with extended equilibration times, although when blastocysts were vitrified using control media at room temperature, the post‐warm survival rate increased (56.8%, 57.3%, 72.5%, respectively, p < .05). The findings show that most cryoprotectant combinations examined proved equally effective at supporting the post‐warm survival of IVP porcine blastocysts. The improved post‐warm survival rate of blastocysts vitrified using media held at room temperature suggests that the cryoprotectant toxicity exerted in 22°C media was reduced. 相似文献
37.
A González-Coloma C Gutiérrez H Hübner H Achenbach D Terrero B M Fraga 《Journal of agricultural and food chemistry》1999,47(10):4419-4424
In this work, we have studied the antifeedant and insecticidal effects of several natural ryanoid diterpenes. These compounds can be classified in two groups according to their chemical structures: ryanodol/isoryanodol-type (nonalkaloidal type) and ryanodine-type (alkaloidal type) ryanoids. The nonalkaloidal ryanoids were isolated from Persea indica (Lauraceae) while the alkaloidal ryanoids (ryanodines and spiganthines) were isolated from Spigelia anthelmia (Loganiaceae). The effects of these compounds on the feeding behavior and performance (with and without piperonyl butoxide pretreatment) of Spodoptera littoralis larvae and Leptinotarsa decemlineata adults indicate that some strongly deterred these insects, L. decemlineata being less sensitive than S. littoralis. Their antifeedant effects did not parallel their toxic action. Additionally, more than 60% of the nonalkaloidal ryanoids were antifeedants and/or toxic in contrast to 30% of active alkaloidal ones, supporting the hypothesis of a ryanodol-specific mode of action in insects. 相似文献
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39.
Christopher Clark Philip Roni Jenna Keeton George Pess 《Fisheries Management and Ecology》2020,27(1):102-110
Despite the popularity of barrier removal as a habitat restoration technique, there are few studies that evaluate the biological effects of restored stream crossings. An extensive post‐treatment study design was used to quantify fish populations (e.g. species, life stage, abundance) and habitat attributes (e.g. gradient, geomorphic channel units) at 32 culvert removal or replacement projects to determine their effectiveness in restoring habitat access for juvenile salmon, Oncorhynchus spp., and steelhead, O. mykiss (Walbaum), in the Columbia River Basin, USA. Anadromous fish (steelhead, Chinook salmon O. tshawytscha [Walbaum]) abundance, juvenile steelhead abundance and habitat conditions were not significantly different between paired reaches (i.e. upstream and downstream of former barrier sites), suggesting these sites are no longer full barriers to movement. This suggests that barrier removal projects on small Columbia Basin streams provide adequate fish passage, increased habitat availability and increased juvenile anadromous fish abundance immediately upstream of former barriers. 相似文献
40.
Jenna Vergeynst Ine Pauwels Raf Baeyens Ans Mouton Tom De Mulder Ingmar Nopens 《Ecology of Freshwater Fish》2021,30(1):73-87
Migrating fish species are worldwide in decline due to several global changes and threats. Among these causes are man‐made structures blocking their freshwater migration routes. Shipping canals with navigation locks play a dual role in this. These canals can serve as an important migration route, offering a short cut between freshwater and the sea. In contrast, the navigation locks may act as barriers to migration, causing delays and migration failures. To better understand these issues for downstream migrating fish, we studied the behaviour of European eels (Anguilla anguilla) in the Albert Canal at two scales. The mid‐scale contained a 27‐km canal pound confined by two navigation lock complexes, in which we released and tracked 86 silver eels. The small scale was a 200 × 150 m area just in front of the most downstream complex of the canal pound, where we analysed the behaviour of 33 eels in relation to the flow field resulting from a computational fluid dynamics (CFD) model. This paper discusses the factors influencing fish behaviour, and the relation between these behaviours on both scales. On the mid‐scale, migration efficiency resulted from a combination of intrinsic behaviour and flow in the canal pound. Also on the small scale, intrinsic behaviour influenced the success to pass the navigation lock. Increasing the flow would create more attraction and passage opportunities and hence facilitate migration through shipping canals, but only if this flow guides the fish through safe passage routes. 相似文献