Expression of CD44 adhesion molecule in rat testis with ischemia/reperfusion injury     

Moon C  Jeong CW  Kim H  Ahn M  Kim S  Shin T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(7):761-764

The expression pattern of CD44 was studied in the rat testis following ischemia/reperfusion (I/R) injury to elucidate the possible role of the CD44 adhesion molecule in acute experimental testicular torsion. Western blot analysis showed that CD44 expression began to increase significantly 24 hr after reperfusion, compared with the normal control; the increased expression persisted until 96 hr after I/R. Immunohistochemistry showed that, in the normal testis, CD44 was constitutively expressed mainly in ED2-positive resident macrophages in the interstitial space. After I/R, the majority of inflammatory cells in the interstitial space surrounding the damaged tubules were ED1-positive macrophages that were CD44-positive. These findings suggest that the significant increase in CD44 expression that occurs during the delayed phase after reperfusion originates from infiltrating macrophages possibly in anticipation of the migration and adhesion of additional macrophages into the affected testis.  相似文献   

Electronic control of friction in silicon pn junctions     

Park JY  Ogletree DF  Thiel PA  Salmeron M 《Science (New York, N.Y.)》2006,313(5784):186

A remarkable dependence of the friction force on carrier concentration was found on doped silicon substrates. The sample was a nearly intrinsic n-type Si(100) wafer patterned with 2-micrometer-wide stripes of highly B-doped p-type material. The counter surface was the tip of an atomic force microscope coated with conductive titanium nitride. The local carrier concentration was controlled through application of forward or reverse bias voltages between the tip and the sample in the p and the n regions. Charge depletion or accumulation resulted in substantial differences in friction force. The results demonstrate the capability to electronically control friction in semiconductor devices, with potential applications in nanoscale machines containing moving parts.  相似文献   

Highly conserved protective epitopes on influenza B viruses   总被引：1，自引：0，他引：1  

C Dreyfus  NS Laursen  T Kwaks  D Zuijdgeest  R Khayat  DC Ekiert  JH Lee  Z Metlagel  MV Bujny  M Jongeneelen  R van der Vlugt  M Lamrani  HJ Korse  E Geelen  Ö Sahin  M Sieuwerts  JP Brakenhoff  R Vogels  OT Li  LL Poon  M Peiris  W Koudstaal  AB Ward  IA Wilson  J Goudsmit  RH Friesen 《Science (New York, N.Y.)》2012,337(6100):1343-1348

Identification of broadly neutralizing antibodies against influenza A viruses has raised hopes for the development of monoclonal antibody-based immunotherapy and "universal" vaccines for influenza. However, a substantial part of the annual flu burden is caused by two cocirculating, antigenically distinct lineages of influenza B viruses. Here, we report human monoclonal antibodies, CR8033, CR8071, and CR9114, that protect mice against lethal challenge from both lineages. Antibodies CR8033 and CR8071 recognize distinct conserved epitopes in the head region of the influenza B hemagglutinin (HA), whereas CR9114 binds a conserved epitope in the HA stem and protects against lethal challenge with influenza A and B viruses. These antibodies may inform on development of monoclonal antibody-based treatments and a universal flu vaccine for all influenza A and B viruses.  相似文献   

Seroprevalence of subtype H3 influenza A virus in South Korean cats     

Jeoung HY  Shin BH  Lee WH  Song DS  Choi YK  Jeong W  Song JY  An DJ 《Journal of Feline Medicine and Surgery》2012,14(10):746-750

To investigate the potential transmission of subtype H3 influenza virus to cats, a serological survey was carried out in South Korea. Serum samples (n = 1027) were obtained from 809 pet cats and 218 domesticated cats living in urban colonies (D-cats) from 2008 to 2010, and tested using an influenza anti-nucleoprotein (NP)-specific enzyme-linked immunosorbent assay (ELISA) and the haemagglutination inhibition (HI) test, which was recommended by the World Organization for Animal Health. Anti-influenza virus antibodies were detected in 3.12% and 2.43% of cat sera tested using the NP-specific ELISA and HI test, respectively. Anti-H3 antibodies were also identified when the HI assay was used for influenza virus serotyping. These data may indicate the sporadic transmission of subtype H3 influenza virus from other infected species to cats in South Korea.  相似文献   

Comparative analysis of physicochemicals and antioxidative properties in new red rice (Oryza sativa L. cv. Gunganghongmi)     

Woo Duck Seo  Jun Young Kim  You-Chun Song  Jun-Hyun Cho  Ki Chang Jang  Sang-Ik Han  Ji-Eun Ra  Seong-Hwan Oh  Hyeon-Jung Kang  Byung-Joo Kim  Nam-In Baek  Rak-Hun Jeong  Min Hee Nam 《Journal of Crop Science and Biotechnology》2013,16(1):63-68

The main objectives of this study were to investigate physicochemicals and antioxidant activities of new red rice (Oryza sativa cv. Gunganghongmi (GH)) by comparing normal brown (Nampyeongbyeo, NB) and reported red rice (Jukjinjubyeo, JB) in Korea. The nutritional constituents, including protein, oil, sugar, fatty acid, GABA, and γ-oryzanol were not significantly different between normal brown and colored rice. However, the ethanol extract of GH showed the highest phenolic content (24.7 ± 1.3 mg g^?1). The ethanol extracts of GH showed higher scavenging activities against DPPH (0.2 mg mL^?1 = 62.1 ± 2.5%) and ABTS (0.2 mg mL^?1 = 63.2 ± 3.5%) radicals. Moreover, GH more inhibited LPS-induced nitric oxide (NO) production (13.2 ± 1.4 μM) than JB (18.3 ± 2.3 μM) and NB (22.1 ± 1.4 μM) at the same concentration (0.2 mg mL^?1) without cytotoxicity. These results suggest that new red rice (GH) would be considered to be new functional rice due to its anti-oxidative effect and high nutrition.  相似文献   

Development of a textile sensibility evaluation system     

Jangwoon Park  Wongi Hong  Jeongrim Jeong  Myungeun Lee  Youngjoo Chae  Minjoo Paik  Gilsoo Cho  Heecheon You 《Fibers and Polymers》2013,14(8):1400-1406

As the demand in the market for a product with a high sensibility has dramatically increased, research has been conducted in designing products for better sensibility; however, most studies have employed a paper-and-pencil (P&P) questionnaire in administering a sensibility evaluation, causing a lack of efficiency and systematicity in sensibility research. The present study developed a computerized textile sensibility evaluation system which can be used to efficiently evaluate the visual, tactile, visual-tactile, and auditory sensibilities of textiles and examined its effectiveness in visual sensibility evaluation compared with the traditional P&P evaluation method. The computerized evaluation system has capabilities of managing information of textile properties, designing a sensibility evaluation experiment, administering a sensibility evaluation, and managing evaluation data for post hoc analysis. The test-retest protocol was administered with a within-subject design for 15 females in their 20 s and 30 s to examine the difference in visual sensibility evaluation between the P&P method and the computer-based method. A high correlation (r=.88～.97) was found in sensibility evaluation between the two methods and the computer-based system showed a higher repeatability within a rater in repeated evaluation (a decrease of 25 % in intra-rater SD), which indicates the computer-based method is an effective alternative to the P&P method in visual sensibility evaluation. The findings of the present study support use of a computerized system for practitioners to efficiently identify preferred characteristics of textiles for the design of sensible clothing.  相似文献   

Effects of conditioned media from human amniotic epithelial cells on corneal alkali injuries in rabbits     

Tae-Hyun Kim  Young-Woo Park  Jae-Sang Ahn  Jeong-Taek Ahn  Se-Eun Kim  Man-Bok Jeong  Min-Su Seo  Kyung-Sun Kang  Kang-Moon Seo 《Journal of veterinary science (Suw?n-si, Korea)》2013,14(1):61-67

This study was performed to evaluate the effects of conditioned media (CM) from human amniotic epithelial cells (HAECs) on the corneal wound healing process. Eighteen rabbits (36 eyes) were used and randomly assigned to three groups according treatment: CM from HAECs (group 1), vehicle alone (group 2), and saline (group 3). Corneal alkali injuries were induced with 1 N sodium hydroxide. Each reagent used for treatment evaluation was injected into the dorsal bulbar subconjunctiva and the area of the corneal epithelial defect was measured every other day. Two animals from each group were euthanized at a time on days 3, 7, and 15, and the cornea was removed for histological examination. The sum of the epithelial defect areas measured on day 0 to day 6 as well as day 0 to day 14 in group 1 was significantly smaller than those of other groups. Histological examination revealed that the group 1 corneas had less inflammatory cell infiltration and showed more intact epithelial features compared to the other groups. These results suggest that CM from HAECs promote corneal wound healing in rabbits.  相似文献   

Comparison of techniques for transdiaphragmatic thoracic drainage after diaphragmatic defect closure in dogs: a cadaveric study     

Hun-Young Yoon  F. A. Mann  Suhwon Lee  Soon-wuk Jeong 《Journal of veterinary science (Suw?n-si, Korea)》2013,14(2):193-197

Four thoracic evacuation techniques for pneumothorax elimination after diaphragmatic defect closure were compared in 40 canine cadavers. After creating a defect in the left side of the diaphragm, thoracic drainage was performed by thoracostomy tube insertion through the defect and a small (DD-SP) or large (DD-LP) puncture created in the caudal mediastinum, or through both the diaphragmatic defect and intact contralateral diaphragm with a small (DI-SP) or large (DI-LP) puncture in made in the caudal mediastinum. Differences in intrapleural pressure (IPP) between the right and left hemithoraxes after air evacuation along with differences in IPP before making a defect and after air evacuation in each hemithorax were calculated. A difference (p ≤ 0.0011) in IPP between the left and right hemithoraxes after air evacuation as well as before making a defect and after air evacuation in the right hemithorax was detected for the DD-SP group. No significant differences (p ≥ 0.0835) were observed for the DI-LP, DD-LP, or DI-SP groups. Creation of a large mediastinal puncture or thoracic evacuation through both a diaphragmatic defect and intact contralateral diaphragm can facilitate proper pneumothorax elimination bilaterally after diaphragmatic defect closure in dogs with a small puncture in the caudal mediastinum.  相似文献   

Amino acid substitutions in gyrA and parC associated with quinolone resistance in nalidixic acid-resistant Salmonella isolates     

Dong Hwa Bae  Ho Jeong Baek  So Jeong Jeong  Young Ju Lee 《Irish veterinary journal》2013,66(1):23

This study was undertaken to identify and characterize amino acid substitutions in gyrA and parC related with quinolone resistance of 27 nalidixic acid-resistant (Na^R) Salmonella isolates collected in poultry slaughterhouses in Korea. A total of 51 Salmonella isolates were detected from 44.8% (47/105) of the total samples from 15 poultry slaughterhouses examined, among which 27 (52.9%) Na^R isolates were detected while ciprofloxacin (Cip) resistance was not present in the isolates. These 27 Na^R isolates of DNA sequencing revealed that it contained three types of gyrA mutations in only D87 codon. Mutations in the D87 codon resulted in substitutions to G in most of the isolates, but D87Y and D87N exchanges were also detected. Although Cip resistance was absent, reduced susceptibility characterized by mutations in gyrA was apparent among Salmonella isolates from poultry slaughterhouses in Korea.  相似文献   

Distribution and temporal prevalence of Theileria orientalis major piroplasm surface protein types in eastern Australian cattle herds     

GJ Eamens  G Bailey  JR Gonsalves  C Jenkins 《Australian veterinary journal》2013,91(8):332-340

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