Liver pathology and immune response in experimental Fasciola hepatica infections of goats   总被引：1，自引：0，他引：1  

Martínez-Moreno A  Jiménez-Luque V  Moreno T  Redondo ES  de las Mulas JM  Pérez J 《Veterinary parasitology》1999,82(1):19-33

The relationship between the immune response and the pathogenesis of the disease was studied in different primary and secondary experimental Fasciola hepatica infections of goats. The establishment of the infection, measured as percentage of recovered flukes at the necropsy, was similar in primarily and secondarily infected animals (between 19.7% and 24.3%), but the hepatic damage was much more severe in secondarily infected goats, as revealed by the levels of serum hepatic enzymes GGT and LDH. Primary infection evolves to chronic fasciolosis that did not induce the development of resistance, since goats were highly susceptible to secondary infection, showing severe acute and chronic hepatic lesions that led to the death of some animals in each group. The immune response to the infection was proved by the production of specific IgG antibodies to ESP of F. hepatica and the involvement of CD3+ T lymphocytes and lambda IgG+ plasma cells in the hepatic infiltrate. Secondary infection did not induce any difference in either IgG response or in the cellular composition of the infiltrate of hepatic lesions, although this was much more extended. However, neither antibodies nor cell-mediated response were protective: there was no correlation between IgG levels and fluke burden and there was no evidence of cell-mediated killing of the parasite. This suggests the existence of some immune evasion mechanisms in goat infection with F. hepatica. The parasite may depress the local inflammatory and immune response, as suggested by the scarcity of CD3+ T cells in the infiltrate surrounding acute migratory tunnels. Moreover, in secondary infected goats can be suspected an immunological damage of the liver, since a very severe infiltrate of immune cells replaced wide areas of hepatic parenchyma and an immune-mediated damage of hepatocytes could occur.  相似文献   

38,XX/38,XY chromosome chimaerism in three feline siblings     

Long SE 《The Veterinary record》1999,145(14):404-405

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桔园柿广翅蜡蝉卵块空间分布图式     

Xia Chugui Zhong Shitian Long Shibing 《湖北农学院学报》1991,(1)

柿广翅蜡蝉在某些柑桔产区新上升为主要害虫。我们于1986年7月间在宜昌柑桔产区对其卵块分布图式进行了调查,通过10组资料分析,得如下结果:(1)由比较频次法测得卵块在桔园呈负二项或截尾负二项分布。(2)由聚集强度测定方法测得卵块在桔园呈聚集分布图式,其分布的基本成份是疏松的个体群,个体群的分布是聚集的,个体内的分布是随机的。(3)由 IwaoM~*指标法求得个体群大小为1～3株(10组资料平均为1.7株)桔树所占面积。(4)由 Blackich 的λ值测得,卵块密度大于6的9组资料其聚集是由于卵块自身聚集行为习性造成(由成虫产卵行为决定),或某些环境因子作用引起。而有一组密度为2.4的资料,其聚集可能完全由于某些环境条件的作用而引起。  相似文献   

新母鸡产蛋前后的管理     

Jim Geary  梁雯静  陈华林 《国外畜牧学(猪与禽)》2001,(3):36-38

后备蛋鸡饲养者必须认识到适度生长的时间限制和和提早开产的能力有着越来越大的矛盾。  相似文献   

Evaluation of use of progesterone to counteract zearalenone toxicosis during early pregnancy in gilts.     

M L Green  D K Stouffer  A B Scheidt  G G Long  M A Diekman 《American journal of veterinary research》1991,52(11):1871-1874

It has been shown that zearalenone disrupts early pregnancy in swine without altering intrauterine content of estradiol 17 beta or progesterone, embryo migration, or estradiol-17 beta synthesis by blastocysts. However, serum concentrations of progesterone were reduced 2 to 3 weeks after mating in gilts that ingested zearalenone. Therefore, progesterone was administered to gilts during early pregnancy to determine whether it could counteract the detrimental actions of zearalenone on embryonic development. Thirty-two crossbred gilts (Hampshire x Chester White x Yorkshire x Duroc) were assigned randomly to a 2 x 2 factorial arrangement of treatments: zearalenone (Z); zearalenone plus progesterone (ZP); progesterone (P); or control (C). From postmating days 4 to 15, Z- and ZP-treated gilts were fed 1 mg of Z/kg of body weight, and P-treated and C gilts were fed ethanol as vehicle in a corn-soybean diet. On postmating days 3 to 15, P- and ZP-treated gilts were injected IM with 100 mg of progesterone, and C and Z-treated gilts were injected with progesterone carrier (15% ethanol, 15% benzyl alcohol, 70% propylene glycol). Blood was collected from gilts by puncture of the jugular vein daily from days 3 to 15, on alternate days from days 17 to 31, and then twice weekly until the end of the experiment. Fetal development was assessed in Z- and ZP-treated gilts on postmating day 47.6 +/- 2.9 by cesarean section and in P-treated and C gilts at slaughter on postmating days 51.2 +/- 3.2. Serum concentrations of progesterone in P-treated gilts were greater on days 7 to 8, 10 to 15, 17, and 19 than in C gilts. Serum concentrations of progesterone were greater on days 8, 10, and 12 in ZP-treated than in C gilts. However, serum concentrations of progesterone were lower in ZP-treated gilts than in C gilts on postmating days 19 to 31.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

家鸡蛋壳组织结构的扫描电镜观察   总被引：4，自引：1，他引：3  

龙小海  田茂春  蒋顺时  向荣淑  徐恢仲  许由  单天锡  黄勇  杜世铭 《中国家禽》1995,(Z1)

用扫描电子显微技术对家鸡蛋壳结构进行研究的结果，进一步直观形象地丰富了我们在这个领域的知识。  相似文献   

Renal neoplasia of snakes     

E R Jacobson  P H Long  R E Miller  L W Kramer  B Beehler  J C Harshbarger  C D Buergelt 《Journal of the American Veterinary Medical Association》1986,189(9):1134-1136

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Necrotic Enteritis in Broiler Chickens I. A Review of the Literature and the Prevalence of the Disease in Ontario   总被引：2，自引：2，他引：0       下载免费PDF全文

J. R. Long 《Canadian journal of veterinary research》1973,37(3):302-308

The available literature on necrotic enteritis in broiler chickens is reviewed.

The records of three poultry diagnostic laboratories in Ontario were examined for the years 1969, 1970 and 1971. During this period 855 (7.7%) of 11,076 consignments of broiler chickens examined were diagnosed as necrotic enteritis. The condition was most common in broilers at three weeks of age, with 66% of all cases occurring in chickens between two and four and one half weeks. The disease occurred throughout the year but it was most common during July, August, September and October. Necrotic enteritis often occurred more than once per year on a farm.

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Histoplasmosis in a harp seal     

T M Wilson  M Kierstead  J R Long 《Journal of the American Veterinary Medical Association》1974,165(9):815-817

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Corticosteroid induction of an isoenzyme of alkaline phosphatase in the dog   总被引：5，自引：0，他引：5  

J L Dorner  W E Hoffmann  G B Long 《American journal of veterinary research》1974,35(11):1457-1458

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