Acute rhabdomyolysis ("tying-up") in standardbred horses. A morphological and biochemical study   总被引：1，自引：0，他引：1  

A Lindholm  H E Johansson  P Kjaersgaard 《Acta veterinaria Scandinavica》1974,15(3):325-339

LINDHOLM, A., H.-E. JOHANSSON & P. KJÆRSGAARD: Acute rhabdomyolysis (“tying-up”) in standardbred horses. A morphological and biochemical study. Acta vet. scand. 1974, 15, 325–339. — Morphological, biochemical and histochemical changes were studied in muscle needle biopsy specimens (gluteus medius) from 59 standardbred trotters with acute clinical symptoms of the “tying-up” disease. All horses had increased levels of serum enzymes SGOT and SCPK. The biopsy specimens were taken at various intervals after onset of clinical symptoms (1–4 hrs., 18–24 hrs. and 2–20 days). Ry light microscopy it was shown that the muscular alterations had a focal distribution and were of the hyalin degeneration type with insignificant inflammatory reaction and slight calcification. The ultrastructural changes apparently commenced with myofibrillar waving, mitochondrial and sarcotubular alterations and terminated with myofibrillar degeneration and necrosis with invasion of inflammatory cells. The inflammatory cells were ultrastructurally similar to monocytes and macrophages. The degenerative changes mainly comprised fast twitch (FT and FTH) fibres as histochemically evidenced by myofibrillar ATPase and alkaline phosphatase staining.Riopsies from diseased muscle 1–4 hrs. after the onset of “tyingup” contained a low muscle concentration of glycogen, ATP and CP and a high concentration of lactate and glucose. Hence it is suggested that the described muscular alterations may be caused by a deranged carbohydrate metabolism caused by a local hypoxia.It was found that the “tying-up” disease resembled idiopathic rhabdomyolysis in man and was thus designated “equine rhabdomyolysis”.histochemistry; horse; rhabdomyolysis; skeletal muscle; “tying-up”; ultrastructure.  相似文献   

A multiresidue analytical method for determining organochlorine,organophosphorus, dinitrophenyl and carbamate pesticides in apples     

Carl E. Johansson 《Pest management science》1978,9(4):313-322

A multiresidue analytical method for the simultaneous extraction of organochlorine, organophosphorus, dinitrophenyl and carbamate pesticides from apples is presented. Extraction is performed with a mixture of toluene and hexane. After clean-up on a Florisil column, and in some cases conversion to derivatives, quantitative determination is performed by electron-capture gas chromatography. Qualitative verification is performed by thin-layer chromatography or gas chromatography-mass spectrometry.  相似文献   

Effect of Stressors on Ova Transport in the Pig     

AM Mwanza  P Englund  S Einarsson  H Kindahl 《Reproduction in domestic animals》2000,35(3-4):188-189

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Perth 2000 AGM date     

Bill Gee AM 《Australian veterinary journal》2000,78(3):141-141

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Synthesis of new tetronamides displaying inhibitory activity against bloom‐forming cyanobacteria     

Jaime AM Acosta  Milandip Karak  Luiz CA Barbosa  John Boukouvalas  Andrea Straforini  Giuseppe Forlani 《Pest management science》2020,76(2):779-788

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Implications of differences in macromolecular composition of stem fractions for processing of Scots pine     

Sara Johansson  Karin Carlqvist  Rashmi Kataria  Thomas Ulvcrona  Urban Bergsten  Mehrdad Arshadi  Mats Galbe  Gunnar Lidén 《Wood Science and Technology》2015,49(5):1037-1054

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Influence of veneer orientation on shape stability of plane laminated veneer products     

Lars Blomqvist  Dick Sandberg  Jimmy Johansson 《Wood material science & engineering》2014,9(4):224-232

One of the most important quality aspects of a laminated veneer product is its shape stability under changing relative humidity (RH). This study aimed to establish an understanding of how the orientation of individual veneers in the laminate, i.e., orientation according to fibre orientation and orientation of the loose (the side with ‘lathe checks’) or tight side of the veneer, affects the shape stability. Three-ply laminates from peeled veneers of beech (Fagus sylvatica L.) were studied. The four types of laminate were the following: loose sides of all veneers in the same direction (cross and parallel centre ply) and loose sides of the outer veneers facing inward (cross and parallel centre ply). Four replicates of each type yielded 16 samples. The samples were exposed to RH cycling at 20% and 85% RH at 20°C, and the shapes of the samples were determined. The shape stability was influenced by the veneer orientation. Laminations with the middle veneer perpendicular to the top and bottom veneer (cross-laminated) showed the best shape stability, especially when the loose sides of the veneers were oriented the same direction. In parallel-laminated veneers, the laminates with opposite directions of the loose sides in the two outermost veneers showed the best shape stability. The major explanation of the behaviour of the laminates is that the loose side expanded more than the tight side from the dry to the humid climate, which was shown by optical 3D deformation analysis (ARAMIS^TM). After RH cycling, the laminates with cross plies showed visible surface checks only when the tight side was facing outwards.  相似文献   

FDG‐PET IN HEALTHY AND EPILEPTIC LAGOTTO ROMAGNOLO DOGS AND CHANGES IN BRAIN GLUCOSE UPTAKE WITH AGE     

Tarja S. Jokinen  Merja Haaparanta‐Solin  Ranno Viitmaa  Tove J. Grönroos  Jarkko Johansson  Luciana Bergamasco  Marjatta Snellman  Liisa Metsähonkala 《Veterinary radiology & ultrasound》2014,55(3):331-341

Regional cerebral metabolism and blood flow can be measured noninvasively with positron emission tomography (PET). 2‐[¹⁸F]fluoro‐2‐deoxy‐D‐glucose (FDG) widely serves as a PET tracer in human patients with epilepsy to identify the seizure focus. The goal of this prospective study was to determine whether juvenile or adult dogs with focal‐onset epilepsy exhibit abnormal cerebral glucose uptake interictally and whether glucose uptake changes with age. We used FDG‐PET to examine six Lagotto Romagnolo dogs with juvenile epilepsy, two dogs with adult‐onset epilepsy, and five control dogs of the same breed at different ages. Three researchers unaware of dog clinical status visually analyzed co‐registered PET and magnetic resonance imaging (MRI) images. Results of the visual PET analyses were compared with electroencephalography (EEG) results. In semiquantitative analysis, relative standard uptake values (SUV) of regions of interest (ROI) drawn to different brain regions were compared between epileptic and control dogs. Visual analysis revealed areas of hypometabolism interictally in five out of six dogs with juvenile epilepsy in the occipital, temporal, and parietal cortex. Changes in EEG occurred in three of these dogs in the same areas where PET showed cortical hypometabolism. Visual analysis showed no abnormalities in cerebral glucose uptake in dogs with adult‐onset epilepsy. Semiquantitative analysis detected no differences between epileptic and control dogs. This result emphasizes the importance of visual analysis in FDG‐PET studies of epileptic dogs. A change in glucose uptake was also detected with age. Glucose uptake values increased between dog ages of 8 and 28 weeks and then remained constant.  相似文献   

CEREBRAL GLUCOSE UTILIZATION MEASURED WITH HIGH RESOLUTION POSITRON EMISSION TOMOGRAPHY IN EPILEPTIC FINNISH SPITZ DOGS AND HEALTHY DOGS     

Ranno Viitmaa  Merja Haaparanta‐Solin  Marjatta Snellman  Sigitas Cizinauskas  Toomas Orro  Erja Kuusela  Jarkko Johansson  Tapio Viljanen  Tarja S. Jokinen  Luciana Bergamasco  Liisa Metsähonkala 《Veterinary radiology & ultrasound》2014,55(4):453-461

In human epileptic patients, changes in cerebral glucose utilization can be detected 2‐deoxy‐2‐[¹⁸F] fluoro‐d ‐glucose positron emission tomography (FDG‐PET). The purpose of this prospective study was to determine whether epileptic dogs might show similar findings. Eleven Finnish Spitz dogs with focal idiopathic epilepsy and six healthy dogs were included. Dogs were examined using electroencephalography (EEG) and FDG‐PET, with epileptic dogs being evaluated during the interictal period. Visual and semi‐quantitative assessment methods of FDG‐PET were compared and contrasted with EEG findings. Three independent observers, unaware of dog clinical status, detected FDG‐PET uptake abnormalities in 9/11 epileptic (82%), and 4/8 healthy dogs (50%). Occipital cortex findings were significantly associated with epileptic status (P = 0.013). Epileptic dogs had significantly lower standardized uptake values (SUVs) in numerous cortical regions, the cerebellum, and the hippocampus compared to the control dogs. The lowest SUVs were found in the occipital lobe. White matter normalized and left‐right asymmetry index values for all pairs of homologous regions did not differ between groups. Visual evaluation of the EEGs was less sensitive (36%) than FDG‐PET. Both diagnostic tests were consensual and specific (100%) for occipital findings, but EEG had a lower sensitivity for detecting lateralized foci than FDG‐PET. Findings supported the use of FDG‐PET as a diagnostic test for dogs with suspected idiopathic epilepsy. Visual and semiquantitative analyses of FDG‐PET scans provided complementary information. Findings also supported the theory that epileptogenesis may occur in multiple brain regions in Finnish Spitz dogs with idiopathic epilepsy.  相似文献   

Giant Piezoelectric Effect in Strontium Titanate at Cryogenic Temperatures     

DE Grupp  AM Goldman 《Science (New York, N.Y.)》1997,276(5311):392-394

Piezoelectric materials have many applications at cryogenic temperatures. However, the piezoelectric response below 10 kelvin is diminished, making the use of these materials somewhat marginal. Results are presented on strontium titanate (SrTiO3), which exhibits a rapidly increasing piezoelectric response with decreasing temperature below 50 kelvin; the magnitude of its response around 1 kelvin is comparable to that of the best materials at room temperature. This "giant" piezoelectric response may open the way for a broad class of applications including use in ultralow-temperature scanning microscopies and in a magnetic field-insensitive thermometer. These observations, and the possible divergence of the mechanical response to electric fields at even lower temperatures, may arise from an apparent quantum critical point at absolute zero.  相似文献