Diagnostic ophthalmology          下载免费PDF全文

Grahn B  Wolfer J  Todhunter P 《The Canadian veterinary journal. La revue veterinaire canadienne》1992,33(11):758-759

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Cubital Subchondral Joint Space Width and CT Osteoabsorptiometry in Dogs With and Without Fragmented Medial Coronoid Process     

Ursula Krotscheck DVM  Diplomate ACVS  Margret S. Thompson DVM  Diplomate ACVR  Rory J. Todhunter BVSc  PhD  Diplomate ACVS  Hussni O. Mohammed PhD 《Veterinary surgery : VS》2014,43(3):330-338

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Seasonal Changes in Cystoseira Myrica and Phosphorus Input at Two Sites of the Red Sea Egyptian Coast     

Abou-Aisha  KH. M.  Shabana  Effat F.  El-Abyad  M. S.  Kobbia  I. A.  Schanz  F. 《Water, air, and soil pollution》1997,93(1-4):199-211

Elevated phosphate concentrations at Safaga and Quseir, Red Sea, Egyptian coast, wererelated to some ecological and nutritional aspects of the macro-alga Cystoseira myrica during1985. The results obtained were compared with those recorded for a non-polluted control site atGhardaqa. Chemical analysis of surface seawater samples revealed that the concentrations of dissolvedphosphate at Safaga and Quseir were 3 and 20 times as much as that at Ghardaqa, respectively.The standing crop of C. myrica showed two peaks in spring and autumn. Maximum biomass yield(491 g m-2) and number of individuals (127 m-2) of C. myrica were recorded in the spring at theGhardaqa site. Quseir C. myrica samples contained significantly higher protein-N, total-N andtotal-P values but lower carbohydrate values than the Safaga and Ghardaqa samples (LSD at 1%level). Tissue N:P molar ratios for C. myrica, Laurencia papillosa and Ulva lactuca collected fromGhardaqa ranged from 68-98, compared to 30-59 for the same species collected at thephosphorus polluted sites at Safaga and Quseir. The carbon levels and the C:N ratios of C. myricaexhibited no significant variations in the three studied sites. However, the C:P ratios of Ghardaqaplants were significantly higher than those of Safaga and Quseir.  相似文献   

Evaluation of a fibrillin 2 gene haplotype associated with hip dysplasia and incipient osteoarthritis in dogs   总被引：1，自引：0，他引：1  

Friedenberg SG  Zhu L  Zhang Z  Foels Wv  Schweitzer PA  Wang W  Fisher PJ  Dykes NL  Corey E  Vernier-Singer M  Jung SW  Sheng X  Hunter LS  McDonough SP  Lust G  Bliss SP  Krotscheck U  Gunn TM  Todhunter RJ 《American journal of veterinary research》2011,72(4):530-540

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Tracheal rupture in two horses     

S L Fubini  R J Todhunter  S L Vivrette  R P Hackett 《Journal of the American Veterinary Medical Association》1985,187(1):69-70

Two horses were admitted for evaluation of diffuse SC emphysema. Diagnosis of ruptured trachea was made by tracheoscopy and radiography. The tracheal cartilages were not involved in either case. One of the defects was small and responded to medical management. The other defect was large and was apposed surgically. Both horses recovered without complications.  相似文献   

Repeatability of dorsolateral subluxation scores in dogs and correlation with macroscopic appearance of hip osteoarthritis.     

G Lust  R J Todhunter  H N Erb  N L Dykes  A J Williams  N I Burton-Wurster  J P Farese 《American journal of veterinary research》2001,62(11):1711-1715

OBJECTIVE: To determine whether dorsolateral subluxation (DLS) scores in young dogs could be used to reliably predict which dogs would develop evidence of hip osteoarthritis and whether DLS scores measured at various ages correlated with each other. ANIMALS: 129 Labrador Retrievers, Greyhounds, and Labrador Retriever-Greyhound crossbreds. PROCEDURES: DLS scores were measured on radiographs taken at 4, 8, and 12 months of age and at necropsy (8 to 36 months of age). At necropsy, the hip joints were examined macroscopically and a score assigned for degree of cartilage degeneration. RESULTS: DLS scores at 4 (n = 35, r(s) = -0.62), 8 (n = 106, r(s) = -0.54), and 12 (n = 15, r(s) = -0.87) months of age were significantly correlated with cartilage degeneration scores, and DLS scores at 8 months of age were significantly correlated with scores obtained at the time of necropsy (n = 39, r(s) = 0.87). The DLS scores at 4 months of age were significantly different from scores at 8 months of age, but scores did not differ significantly thereafter. Likelihood ratios for cartilage lesions for low (< 45%), intermediate (> or = 45 but < or = 55%), and high (> 55%) DLS scores at 8 months of age were 8.0, 2.6, and 0.2, respectively. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that DLS score at 8 months of age was a reasonable, albeit imperfect, predictor of the condition of the hip joint cartilage at necropsy. Thus, the DLS method might be useful for early identification of dogs with hip dysplasia.  相似文献   

Costs associated with selected preventive practices and with episodes of clinical mastitis in nine herds with low somatic cell counts     

K H Hoblet  G D Schnitkey  D Arbaugh  J S Hogan  K L Smith  P S Schoenberger  D A Todhunter  W D Hueston  D E Pritchard  G L Bowman 《Journal of the American Veterinary Medical Association》1991,199(2):190-196

Nine dairy herds (mean size, 149 cows) with bulk-tank milk somatic cell counts of less than 300,000 cells/ml and greater than 80% of cows with Dairy Herd Improvement Association linear somatic cell counts less than or equal to 4 were selected for study. Each herd was monitored for 12 consecutive months. Duplicate quarter-milk specimens were collected from each cow for bacteriologic culturing at beginning of lactation, cessation of lactation, and at the time of each clinical episode of mastitis. Streptococcus agalactiae was never isolated and Staphylococcus aureus was isolated from less than 1% of all quarters. There were 554 episodes of clinical mastitis. During the year of study, the incidence rate of clinical mastitis varied from 15.6 to 63.7% of cows among the 9 herds. Mean costs per cow per year in herd for mastitis prevention were: $10 for paper towels, $3 for nonlactating cow treatment, and $10 for teat disinfectants. Mean cost associated with clinical mastitis was $107/episode. Approximately 84% ($90) of the costs attributed to a clinical episode were associated with decreased milk production and nonsalable milk. Costs of medication and professional veterinary fees per clinical episode varied significantly among the 9 herds. Three of the herds did not have a veterinarian treat a clinical episode of mastitis during the year of study even though 2 of these herds had the first and third highest incidence rates of clinical mastitis. When calculated on a per cow in herd basis, mean costs of $40/cow/year were attributed to clinical mastitis.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Technical note: Use of marker-based relationships with multiple-trait derivative-free restricted maximal likelihood     

Zhang Z  Todhunter RJ  Buckler ES  Van Vleck LD 《Journal of animal science》2007,85(4):881-885

The widespread use of the set of multiple-trait derivative-free REML programs for prediction of breeding values and estimation of variance components has led to significant improvement in traits of economic importance. The initial version of this software package, however, was generally limited to pedigree-based relationships. With continued advances in genomic research and the increased availability of genotyping, relationships based on molecular markers are obtainable and desirable. The addition of a new program to the set of multiple-trait derivative-free REML programs is described that allows users the flexibility to calculate relationships using standard pedigree files or an arbitrary relationship matrix based on genetic marker information. The strategy behind this modification and its design is described. An application is illustrated in a QTL association study for canine hip dysplasia.  相似文献   

Quantitative genetics of secondary hip joint osteoarthritis in a Labrador Retriever-Greyhound pedigree     

Hays L  Zhang Z  Mateescu RG  Lust G  Burton-Wurster NI  Todhunter RJ 《American journal of veterinary research》2007,68(1):35-41

OBJECTIVE: To evaluate the quantitative inheritance of secondary hip joint osteoarthritis in a canine pedigree. ANIMALS: 137 Labrador Retrievers, Greyhounds, and mixed-breed dogs. PROCEDURES: Necropsy scores ranging from 0 to 4 were obtained for each hip joint. Seven unaffected Greyhounds with normal hip joint conformation were also used for genetic modeling, but were not euthanized. Sixty-six male and 71 female dogs were allocated to 2 groups (< or = 12 months of age and > 12 months of age). Statistical models were developed to establish the inheritance pattern of hip joint osteoarthritis that developed secondary to hip dysplasia. RESULTS: 62 dogs had evidence of osteoarthritis in a hip joint, and 75 had no evidence of osteoarthritis. After sex was adjusted for, the necropsy score was found to be inherited additively but without dominance. Each Labrador Retriever allele increased the necropsy score by 0.7 to 0.9 points, compared with the Greyhound allele, and male sex increased the necropsy score 0.74 over female sex. Approximately 10% of the variation in necropsy score was attributable to the litter of puppies' origin. CONCLUSIONS AND CLINICAL RELEVANCE: Because secondary hip joint osteoarthritis is inherited additively, selection pressure could be applied to reduce its incidence. Similar statistical models can be used in linkage and association mapping to detect the genes in the underlying quantitative trait loci that contribute to hip joint osteoarthritis.  相似文献   

Long‐Term Functional Outcome of Tibial Plateau Leveling Osteotomy Versus Extracapsular Repair in a Heterogeneous Population of Dogs     

Samantha A. Nelson MA  DVM  Ursula Krotscheck DVM  Diplomate ACVS  Jeremy Rawlinson PhD  Rory J. Todhunter BVSc  PhD  Diplomate ACVS  Zhiwu Zhang PhD  Hussni Mohammed PhD 《Veterinary surgery : VS》2013,42(1):38-50

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