Abamectin toxicity in farm dogs     

KH Parton 《New Zealand veterinary journal》2013,61(1)

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Exposure of mares to processionary caterpillars (Ochrogaster lunifer) in early pregnancy: An additional dimension to equine amnionitis and fetal loss     

A. J. Cawdell‐Smith  K. H. Todhunter  N. R. Perkins  W. L. Bryden 《Equine veterinary journal》2013,45(6):755-760

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The Influencing Factor of In Vitro Fertilization and Embryonic Transfer in the Domestic Fowl (Gallus domesticus)     

BC Li  W Li  H Chen  YN Zhang  ZT Zhang  XY Wang  B Gao  TC Dou  KH Wang 《Reproduction in domestic animals》2013,48(3):368-372

This study was conducted to explore the influencing factors of ova in vitro fertilization (IVF) and transfer of the fertilized ova into the oviduct of recipient hens. The efficiency of fertilization was compared using three aspects: (i) the different time of ova collection and transfer, (ii) egg‐laying period of recipient hen; and (iii) semen volume. The following results are observed: 72%, 40% and 0% of ova were found in ovarian sac in 30～40 min, 50～60 min and more than 90 min post‐oviposition, respectively; 20%, 18%, 14% and 5.8% of ova were fertilized with 0.1, 0.2, 0.5 and 1.0 ml semen, respectively; and 33% and 100% of healthy chickens were hatched from fertile ova with 0.1 and 0.5 ml of semen, respectively. All oocytes obtained from ovary and mid‐oviduct were unfertilized. Embryos were transferred into recipient hens 30 min ± 10 min post‐oviposition, and 70% of shelled eggs were produced. There were no eggs produced in the other transfer times. This demonstrated that live chicken can be obtained by IVF of ova collected shortly after oviposition. It was important that the ovum was transferred into the oviduct infundibulum of recipient hens immediately or shortly after oviposition.  相似文献   

Clade 2.3.4.4 avian influenza A (H5N8) outbreak in commercial poultry,Iran, 2016: the first report and update data     

Ghafouri  Seyed Ali  GhalyanchiLangeroudi  Arash  Maghsoudloo  Hossein  KH Farahani  Reza  Abdollahi  Hamed  Tehrani  Farshad  Fallah  Mohammad Hossein 《Tropical animal health and production》2017,49(5):1089-1093

Tropical Animal Health and Production - In 2010, H5N8 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/1996 lineage dramatically affected poultry and wild birds in Asia,...  相似文献   

Effect of polysulfated glycosaminoglycan on DNA content and proteoglycan metabolism in normal and osteoarthritic canine articular cartilage explants     

Sevalla K  Todhunter RJ  Vernier-Singer M  Budsberg SC 《Veterinary surgery : VS》2000,29(5):407-414

OBJECTIVE: To study the effect of polysulfated glycosaminoglycan (PSGAG) on proteoglycan metabolism and DNA content of control and osteoarthritic (OA) cartilage. STUDY DESIGN: An in vitro study comparing the effects of PSGAG on articular cartilage explants from canine stifle joints with and without chronic OA after transection of the left cranial cruciate ligament. SAMPLE POPULATION: Five large cross-breed dogs. METHODS: Cartilage explants (6 to 13 per treatment group) from the medial side of the femoral trochlea and medial femoral condyle from both stifles of each dog were incubated in a defined medium containing 0, 0.05, 0.5, or 5 mg/mL of PSGAG. After 72 hours in culture, explants were pulsed for 6 hours with sodium [35S]sulfate. Aminophenylmercuric acetate (APMA) was used to activate endogenous neutral matrix metalloproteinases (MMPs) and induce proteoglycan degradation in the radiolabeled explants. DNA content and radioactivity were measured in papain-digested explants, and radioactivity was measured in the medium by liquid scintillation counting. Proteoglycan synthesis and degradation were calculated. Cartilage was examined histologically for signs of OA. A mixed model analysis of variance and linear contrasts were used to test for significant (P < .05) effects of OA and treatment with PSGAG. RESULTS: Transection of the cranial cruciate ligament produced OA in operated joints. DNA content and proteoglycan synthesis of OA cartilage were significantly lower than in cartilage from control joints. For both DNA content and proteoglycan synthesis, significant interactions occurred between the concentration of PSGAG and whether the articular cartilage was from OA or control joints. The two lower concentrations of PSGAG (0.05 and 0.5 mg/mL) predominantly increased DNA content in OA cartilage (7 and 18%, respectively, compared with 0 mg/mL PSGAG) while the highest concentration (5 mg/mL) predominantly increased DNA content in control cartilage (30% compared with 0 mg/mL PSGAG). PSGAG at .05 mg/mL predominantly decreased proteoglycan synthesis in OA cartilage (19% reduction compared with 0 mg/mL PSGAG) while PSGAG at .5 and 5 mg/mL predominantly decreased proteoglycan synthesis in control cartilage (17 and 55% reduction, respectively, compared with 0 mg/mL PSGAG). Following activation of MMPs, PSGAG caused a dose-dependent decrease in degradation of radiolabeled proteoglycan in both OA and control cartilage. CONCLUSIONS: OA cartilage was responsive to treatment with PSGAG at 100-fold lower concentration than control cartilage. When treated with PSGAG, articular cartilage explants maintained or increased DNA content at the expense of proteoglycan synthesis. Following MMP activation, proteoglycan degradation was inhibited in OA and control explants in a dose-dependent manner. CLINICAL RELEVANCE: If the results of this study extend to in vivo use, treatment with PSGAG may modify the progression of OA in articular cartilage by maintaining chondrocyte viability or stimulating chondrocyte division as well as protecting against extracellular matrix degradation.  相似文献   

Comparative histopathological study of the canine thyroid gland in London and Munich     

KH. ZARIN  T. HÄNICHEN† 《The Journal of small animal practice》1974,15(5):329-342

The thyroid glands of two series of ninety-nine unselected dogs from consecutive autopsies in London and in Munich were examined histologically. The prevalence of goitre and of neoplasia was distinctly higher in dogs in the Munich series.
Résumé. On a examiné de façon histologiyue les glandes thyroïdes de deux séries de quatrevingt-dix-neufs chiens d'après des autopsies consécutives à Londres et à Munich. La prédominance de goîtres et de néoplasie était nettement plus élevée chez les chien de la série de Munich
Zusammenfassung. Die Schilddrüsen von zwei Serien von 99 Hunden Wurden von darauf-folgenden Autopsien in London und München histologisch untersucht. Das Vorkommenwon Kropf und Neoplasia war entschieden höher in den Hunden der Munchener Serie.  相似文献   

Herniation of the abdominal wall in pregnant mares     

R R Hanson  R J Todhunter 《Journal of the American Veterinary Medical Association》1986,189(7):790-793

Abdominal wall hernia was detected in 4 pregnant mares. Antemortem diagnosis of the specific abdominal wall lesion was difficult. Ventral deviation of the abdomen, associated abdominal wall edema, and pain indicated rupture of the prepubic tendon. Three mares examined at necropsy did not have a rupture of the prepubic tendon but did have herniation of the abdominal wall. Abdominal pain was severe and was compounded by incarceration or entrapment of viscus.  相似文献   

Comparison of measurements of dorsolateral subluxation of the femoral head and maximal passive laxity for evaluation of the coxofemoral joint in dogs     

Farese JP  Lust G  Williams AJ  Dykes NL  Todhunter RJ 《American journal of veterinary research》1999,60(12):1571-1576

OBJECTIVE: To determine whether dorsolateral subluxation (DLS) of the femoral head reflects osseous conformation of the coxofemoral (hip) joint and represents a property distinct from maximum passive laxity of the hip joint in dogs. ANIMALS: 14 Labrador Retrievers, 16 Greyhounds, 58 Greyhound-Labrador Retriever mixed-breed dogs, and 1 Rottweiler. PROCEDURES: DLS of the femoral head (DLS score) and passive laxity of the hip joint (distraction index) were determined radiographically in 3 groups of dogs: not treated (167 joints of 84 dogs); before and after injecting 2 ml of hyaluronan into 25 hip joints of 13 dogs; and before and after unilateral triple pelvic osteotomy in 5 dogs. Results of the 2 methods were compared for each group. RESULTS: In untreated dogs, the correlation coefficient (r) of DLS score versus distraction index was -0.73 and -0.69 for 84 left and 83 right hip joints, respectively. Mean coefficient of determination (r2) for both hips was 0.5. Mean DLS score did not differ before and after intra-articular injection of hyaluronan into either hip joint, whereas mean distraction index increased significantly after intra-articular injection. Unilateral triple pelvic osteotomy resulted in a significant increase in DLS score, compared with values obtained before surgery. However, distraction index before and after surgery did not differ significantly. CONCLUSIONS AND CLINICAL RELEVANCE: The DLS test assesses the congruity of the acetabulum and the femoral head in a canine hip joint and thus represents a characteristic distinct from maximum passive laxity. The DLS score and the distraction index evaluate different components of hip joint stability.  相似文献   

Identification of quantitative trait loci for osteoarthritis of hip joints in dogs   总被引：1，自引：0，他引：1  

Mateescu RG  Burton-Wurster NI  Tsai K  Phavaphutanon J  Zhang Z  Murphy KE  Lust G  Todhunter RJ 《American journal of veterinary research》2008,69(10):1294-1300

OBJECTIVE: To identify quantitative trait loci (QTL) associated with osteoarthritis (OA) of hip joints of dogs by use of a whole-genome microsatellite scan. ANIMALS: 116 founder, backcross, F1, and F2 dogs from a crossbred pedigree. PROCEDURES: Necropsy scores and an optimized set of 342 microsatellite markers were used for interval mapping by means of a combined backcross and F2 design module from an online statistical program. Breed and sex were included in the model as fixed effects. Age of dog at necropsy and body weight at 8 months of age were also included in the model as covariates. The chromosomal location at which the highest F score was obtained was considered the best estimate of a QTL position. Chromosome-wide significance thresholds were determined empirically from 10,000 permutations of marker genotypes. RESULTS: 4 chromosomes contained putative QTL for OA of hip joints in dogs at the 5% chromosome-wide significance threshold: chromosomes 5, 18, 23, and 31. CONCLUSIONS AND CLINICAL RELEVANCE: Osteoarthritis of canine hip joints is a complex disease to which many genes and environmental factors contribute. Identification of contributing QTL is a strategy to elucidate the genetic mechanisms that underlie this disease. Refinement of the putative QTL and subsequent candidate gene studies are needed to identify the genes involved in the disease process.  相似文献   

播种机参数和打穴铲结构对投种影响的计算机仿真   总被引：4，自引：2，他引：2  

李成华  马成林  于海业  KH. Kromer 《农业机械学报》1999,30(3):35-38

根据铲式成穴器与倾斜圆盘勺式排种器组合设计成的打穴播种机的结构特点,建立了种子下落过程中运动轨迹的参数方程。以此为基础分析了播种机双向倾角、排种器投种角和打穴铲结构参数对种子在打穴铲内自由下落过程的影响,进而确定了打穴铲几何尺寸的设计原则。  相似文献