Inhibition of Biofilm Formation by Modified Oxylipins from the Shipworm Symbiont Teredinibacter turnerae     

Noel M. Lacerna  II  Cydee Marie V. Ramones  Jose Miguel D. Robes  Myra Ruth D. Picart  Jortan O. Tun  Bailey W. Miller  Margo G. Haygood  Eric W. Schmidt  Lilibeth A. Salvador-Reyes  Gisela P. Concepcion 《Marine drugs》2020,18(12)

The bioactivity-guided purification of the culture broth of the shipworm endosymbiont Teredinibacter turnerae strain 991H.S.0a.06 yielded a new fatty acid, turneroic acid (1), and two previously described oxylipins (2–3). Turneroic acid (1) is an 18-carbon fatty acid decorated by a hydroxy group and an epoxide ring. Compounds 1–3 inhibited bacterial biofilm formation in Staphylococcus epidermidis, while only 3 showed antimicrobial activity against planktonic S. epidermidis. Comparison of the bioactivity of 1–3 with structurally related compounds indicated the importance of the epoxide moiety for selective and potent biofilm inhibition.  相似文献   

Nd:YAG Laser Treatment of a Vestibulovaginal Varicosity in a 15-Year-Old Pregnant Mare     

Catherine DeLuca  John J. Dascanio  Douglass B. Berry II 《Journal of Equine Veterinary Science》2007

A 15-year-old, pregnant Dutch Warmblood mare was exhibiting intermittent hemorrhage secondary to a large vestibulovaginal varicosity. The vessel was reduced with transendoscopic Nd:YAG laser photocoagulation. This technique is minimally invasive compared with traditional surgical ligation, and significantly decreases the risk of severe hemorrhage, especially with advancing pregnancy. One laser treatment resulted in complete reduction in vessel size and allowed the pregnancy to continue to term without incident or further vaginal hemorrhage.  相似文献   

NAB 365, a beta 2-receptor sympathomimetic agent: clinical experience in horses with lung disease   总被引：2，自引：0，他引：2  

II. L. SASSE  R. HAJER 《Journal of veterinary pharmacology and therapeutics》1978,1(3):241-244

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Nucleotide sequencing, whitefly transmission, and screening tomato for resistance against two newly described begomoviruses in bangladesh     

Maruthi MN  Alam SN  Kader KA  Rekha AR  Cork A  Colvin J 《Phytopathology》2005,95(12):1472-1481

ABSTRACT The molecular diversity of Tomato leaf curl viruses (ToLCVs), from the two main tomato growing areas of Jessore and Joydebpur, Bangladesh, was investigated. The viral DNA was amplified from tomato plants exhibiting mild and severe symptoms by polymerase chain reaction, and the complete genomes of the ToLCVs were sequenced. An isolate of the bipartite Tomato leaf curl New Delhi virus-Severe (ToLCNDV-Svr) was associated with the severe symptom phenotype from Jessore (ToLCNDV-Svr[Jes]). A previously undescribed monopartite virus, designated Tomato leaf curl Joydebpur virus-Mild (ToLCJV-Mld), was sequenced from plants showing mild symptoms. ToLCNDV-Svr[Jes] was most closely related to ToLCNDV-[Lucknow] at 95.7% nucleotide (nt) identity and Tomato leaf curl Gujarat virus-[Varanasi] at 90.6% nt identity, based on DNA-A and -B component sequences. ToLCJV-Mld was similar to Pepper leaf curl Bangladesh virus at 87.1% DNA-A nt identity. Identification of ToLCNDV-Svr[Jes] and ToLCJV-Mld was in addition to the previously described Tomato leaf curl Bangladesh virus, with which they shared 73.2 and 86.0% DNA-A nt identities, thus demonstrating the existence of at least three distinct viruses infecting tomato in Bangladesh. Nucleotide identities and placement in phylogenetic trees suggested that the three ToLCVs may have had different evolutionary pathways. The whitefly, Bemisia tabaci, transmitted the viruses of this study equally efficiently. Four tomato cultivars (TLB111, TLB130, TLB133, and TLB182) resistant/ tolerant to South Indian ToLCV were screened against the Bangladesh ToLCVs in 2003-04. Although challenged by diverse viruses and potentially mixed infections, disease incidence remained low (6 to 45%) in the resistant cultivars compared with local cultivars (68 to 100%).  相似文献   

Prevalence of Brachyspira species isolated from diarrhoeic pigs in Brazil     

Barcellos DE  Mathiesen MR  de Uzeda M  Kader II  Duhamel GE 《The Veterinary record》2000,146(14):398-403

Pathogenic intestinal spirochaetes of pigs include Brachyspira (formerly Serpulina) hyodysenteriae, the cause of swine dysentery, and Brachyspira pilosicoli, the cause of porcine colonic spirochetosis (PCS). The purpose of this study was to assess the relative importance of Brachyspira species in diarrhoeal disease of growing pigs on farms in southern Brazil. The intensity and pattern of haemolysis, the production of indole and the hydrolysis of hippurate by reference and field porcine intestinal spirochaetes were compared with 16S-ribosomal RNA (mRNA)- and 23S-rRNA-based polymerase chain reaction assays for the identification of B hyodysenteriae and B pilosicoli. Between July and October 1998, 206 rectal swabs were taken from pigs on 17 farms with a history of diarrhoea developing within 30 days after they had been moved from nursery to growing facilities. Of 49 beta-haemolytic spirochaetes that were cultured, 29 (59.2 per cent) were grown in pure culture for phenotypic and genotypic characterisation, leaving 20 untyped. Of the 29 typed isolates, eight isolates obtained from six farms were identified as B hyodysenteriae, and 15 isolates obtained from seven other farms were identified as B pilosicoli; the remaining six isolates were identified as weakly beta-haemolytic commensal spirochaetes. There was complete agreement between the results of the phenotypic and genotypic analyses.  相似文献   

IMAGING DIAGNOSIS—OCCIPITOATLANTOAXIAL MALFORMATION IN A MINIATURE HORSE FOAL     

Diana S.  Rosenstein  DVM  MS  Harold C.  Schott II  DVMP hD  Russ L.  Stickle  DVM 《Veterinary radiology & ultrasound》2000,41(3):218-219

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A Genome-Wide Association Study for Morphometric Traits in Quarter Horse     

Camila Tangari Meira  Michel Marques Farah  Marina R.S. Fortes  Stephen S. Moore  Guilherme L. Pereira  Josineudson Augusto II V. Silva  Marcílio Dias S. da Mota  Rogério Abdallah Curi 《Journal of Equine Veterinary Science》2014

A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 from a cutting population, which were genotyped using the Illumina EquineSNP50 chip. Association analysis was performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) using Qxpak5 software. The following traits were measured: weight (W), rump length (RL), and body length (BL). These morphometric traits are important for the best performance in race and cutting events. For weight, three SNPs associated (P < .0001) were found on chromosomes (Equus caballus autosomes [ECA]) 2 and 3. For rump length, eight SNPs associated (P < .0001) were found on ECA 2, 3, 6, 7, 9, 21, and 26. On ECA 3 and ECA 8, two SNPs were associated (P < .0001) with body length. So, a total of 13 important chromosomal regions were identified with Q values of 0.53 (SNPs for W), 0.40 (SNPs for RL), and 0.99 (SNPs for BL). Positional and functional candidate genes emerging from this study were WWOX and AAVPR1A. Further studies are required to confirm these associations in other populations.  相似文献   

Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing   总被引：23，自引：0，他引：23  

Gil MI  Tomás-Barberán FA  Hess-Pierce B  Holcroft DM  Kader AA 《Journal of agricultural and food chemistry》2000,48(10):4581-4589

The antioxidant activity of pomegranate juices was evaluated by four different methods (ABTS, DPPH, DMPD, and FRAP) and compared to those of red wine and a green tea infusion. Commercial pomegranate juices showed an antioxidant activity (18-20 TEAC) three times higher than those of red wine and green tea (6-8 TEAC). The activity was higher in commercial juices extracted from whole pomegranates than in experimental juices obtained from the arils only (12-14 TEAC). HPLC-DAD and HPLC-MS analyses of the juices revealed that commercial juices contained the pomegranate tannin punicalagin (1500-1900 mg/L) while only traces of this compound were detected in the experimental juice obtained from arils in the laboratory. This shows that pomegranate industrial processing extracts some of the hydrolyzable tannins present in the fruit rind. This could account for the higher antioxidant activity of commercial juices compared to the experimental ones. In addition, anthocyanins, ellagic acid derivatives, and hydrolyzable tannins were detected and quantified in the pomegranate juices.  相似文献   

Relationship between reproductive and productive traits in Holstein cattle using multivariate analysis     

Pablo Dominguez-Castaño  Matheus Henrique Vargas de Oliveira  Lenira El Faro  Josineudson Augusto II de Vasconcelos Silva 《Reproduction in domestic animals》2020,55(7):770-776

Multivariate procedures are used for the extraction of variables from the correlation matrix of phenotypes in order to identify those traits that explain the largest proportion of phenotypic variation and to evaluate the relationship structure between these traits. The reproductive traits (days from calving to first estrus [CFE], days from calving to last service [CLS], calving interval [CI] and gestation length [GL]) and milk production traits (milk yield at 305 days of lactation [MY305], peak yield [PY] and milk yield per day of calving interval [MYCI]) of 5,217 Holstein females (primiparous and multiparous) were measured. Principal component analysis (PCA) and factor analysis of the correlation matrix were used to estimate the correlation between traits. Analysis grouped the seven traits into three principal components and four latent factors that retained approximately 81.5% and 88.9% of the total variation of the data, respectively. The production variables exhibited positive phenotypic correlation coefficients of high magnitude (>.67). The phenotypic correlation estimates between the productive and reproductive traits were low, ranging from .13 to .22. A strong association (.99) was observed between CLS and CI. Our results indicate that multivariate analysis was effective in generating correlations between the traits studied, grouping the seven traits in a smaller number of variables that retained approximately 81% of the total variation of the data.  相似文献   

新疆石榴树害螨:如今细须螨—中国新纪录     

阿布都克尤木·卡德尔  林坚贞  张艳璇  徐兵强  朱晓锋  宋博  杨森 《新疆农业科学》2015,(2):275-277,393

【目的】叶螨是一类重要的农业有害生物,近年来在新疆喀什地区石榴害螨危害呈上升趋势,严重制约该地区石榴产业的可持续健康发展。调查新疆喀什市周边石榴产区,采集石榴树优势种害螨标本,鉴定种类,为该螨生物学、生态学特性研究打基础。【方法】利用吸虫管、微小虫分离器、镊子、解剖针、毛笔、叶螨保存液等工具,采用小毛笔蘸液直接黏取法、敲打振落法手段采集害螨标本。【结果】通过采集鉴定新疆喀什市周边石榴树害螨为如今细须螨(Tenuipalpus hornotinus Chaudhri,1971)中国新记录种,描述了该螨种区别其它近似种鉴别特征及形态特征。【结论】该种12♀螨,2008年采自新疆喀什市阿瓦提乡石榴树上。  相似文献