A cat with myelodysplastic syndrome by administration of the methylation inhibitor Azacytidine     

Masaharu HISASUE  Mina TANAKA  Sakurako NEO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2022,84(1):142

A 5-year-old female cat with nonregenerative anemia and thrombocytopenia was diagnosed with myelodysplastic syndromes (MDS), since peripheral blood and bone marrow (BM) examination revealed various dysplasias and a blast ratio of 19%. Chemotherapy with azacytidine (AZA; 70–35 mg/m², 3–5 days, three cycles) and treatment with prednisolone, antibiotics, and vitamin K2, and blood transfusion were performed. On day 106, blast cells and dysplasia had decreased in the BM, and the cat remained alive for at least 1,474 days. This report is the first on feline MDS treated with AZA, suggesting appropriate drug dosage, interval and effective combination should be investigated and the pharmacological and cell biological mechanisms needs to be elucidated in the future.  相似文献   

Identification of a Bisegmented Double-stranded RNA Virus (Picobirnavirus) in Faeces of Giant Anteaters (Myrmecophaga tridactyla)     

I. R. HAGA  S. S. MARTINS  S. T. HOSOMI  F. VICENTINI  H. TANAKA  M. S. V. GATTI 《Veterinary journal (London, England : 1997)》1999,158(3):61

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Changes in the ovary and the peripheral concentrations of sex hormones after the aspiration of follicular fluid from the spontaneous follicular cysts of dairy cows     

Kazuhiro KENGAKU  Tomomi TANAKA  Hideo KAMOMAE 《The Journal of reproduction and development》2021,67(5):332

The aim of the present study was to clarify the ovarian and hormonal dynamics after the aspiration of follicular fluid in cows with follicular cysts. Follicular fluid was aspirated from the follicular cysts and follicles that were fated to become cystic follicles and other coexisting normal follicles, respectively, in lactating cows (n = 3). After the aspiration procedure, new follicles developed and reached a diameter of 25 mm without ovulation within 13–19 days. The plasma concentrations of inhibin decreased and follicle-stimulating hormone increased rapidly after the aspiration procedure, and subsequently increased and decreased, respectively, as a new follicle grew. No luteal structures developed after the aspiration procedure, and the animals’ plasma progesterone levels remained low. The present study indicates that the cystic follicles are never luteinized by the aspiration of follicular fluid, and consequently, new follicular cysts are observed to repeatedly develop.  相似文献   

Congenital cutaneous fibropapillomatosis without evidences of papillomavirus infection in a Holstein-Friesian calf     

Yusuke TANAKA  Yuka TAGAINO  Shotaro NAKAGUN  Takayuki MINESHIGE  Kenichi WATANABE  Hisashi INOKUMA  Yoshiyasu KOBAYASHI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(12):1852

A male Holstein-Friesian calf was born with multiple, cauliflower-like, pale pink cutaneous masses on the head and limbs. On histopathological examination, the cutaneous masses were diagnosed as congenital cutaneous fibropapillomatosis. Those lesions involved focal proliferation of sebaceous gland in the dermis. There were no histological findings to suggest bovine papillomavirus infection, such as the presence of intranuclear inclusion bodies, large keratohyalin granules, and koilocytosis. Furthermore, papillomaviral antigens and DNA were not detected by immunohistochemistry and polymerase chain reaction, respectively. These results suggested that there was no association between these cutaneous lesions and bovine papillomavirus infection, and the lesions were considered as harmartomatous changes.  相似文献   

Chub mackerel larvae fed fish larvae can swim faster than those fed rotifers and Artemia nauplii     

REIJI  MASUDA  JUN  SHOJI  MITSUHIRO  AOYAMA  MASARU  TANAKA 《Fisheries Science》2002,68(2):320-324

ABSTRACT: Developmental changes of swimming speed were analysed in the chub mackerel Scomber japonicus raised on two distinct dietary regimens. One group was fed only zooplankton such as rotifers and Artemia nauplii (R group) and the other group was fed rotifers plus red sea bream Pagrus major larvae (Pm group). Fish from the Pm group grew faster than those from the R group, and both the cruise and burst swimming speeds were faster for the Pm group even when match-sized comparisons were made. Fish in the Pm group attained a standard length (SL) of 17.5 mm by day 14 and their cruise and burst swimming speeds were 5.39 SL/s and 18.45 SL/s, whereas the R group attained 17.35 mm SL by day 17 and their cruise and burst swimming speeds were 4.28 SL/s and 13.98 SL/s. The results suggest that the swimming speed of chub mackerel in the wild would develop differently depending on the food resources they happen to encounter.  相似文献   

A survey of chicken sera for antibody to atypical avian rotavirus of duck origin, in Japan     

K Takase  T Uchimura  N Katsuki  M Yamamoto 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1990,52(6):1319-1321

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The effects of migration on the immunity of Black-Headed Gulls (Chroicocephalus ridibundus: Laridae)     

Nana USHINE  Osamu KURATA  Yoshikazu TANAKA  Tatsuo SATO  Yoshihiro KURAHASHI  Shin-ichi HAYAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2020,82(11):1619

In order to elucidate the relationship between migration period and immunity related to susceptibility, we conducted research on Black-headed gulls (Chroicocephalus ridibundus). We captured 260 gulls and collected their peripheral blood. Their leukocyte (WBC) count, percentages of heterophils (Het) and lymphocytes (Lym), heterophil and lymphocyte ratio (H/L ratio), and CD4 and CD8α expression levels (CD4 and CD8α, respectively) were quantitatively analyzed over three migration periods (Autumn migration, Wintering, Spring migration). In Adult gulls, WBC counts and CD4 levels significantly increased. Moreover, the Het and H/L ratio decreased from the Autumn migration to Wintering. Conversely, only WBC counts and CD4 levels measurements significantly decreased from Wintering to Spring migration (P<0.05). The tested parameters of the Tokyo-bay population show a greater significant difference than the measurements of immunity of the Mikawa-bay population. This study suggests that the migratory period has a negative effect on an aspect of the immune system. Including the period-difference in the immune systems in the local population, it is necessary to investigate the relationship between the ecology of migratory birds and their immunity.  相似文献   

Cerebellar Ataxia Suspected to Be Caused by Oxytropis glabra Poisoning in Western Mongolian Goats     

Shuji TAKEDA  Hiroyuki TANAKA  Akinori SHIMADA  Takehito MORITA  Atsushi ISHIHARA  Altanchimeg ADILBISH  Bayarmunkh DELGERMAA  Oyuntsetseg GUNGAA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(6):839-846

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Visualizing picometric quantum ripples of ultrafast wave-packet interference     

Katsuki H  Chiba H  Girard B  Meier C  Ohmori K 《Science (New York, N.Y.)》2006,311(5767):1589-1592

Interference fringes in vibrating molecules are a signature of quantum mechanics, but are often so short-lived and closely spaced that they elude visualization. We have experimentally visualized dynamical quantum interferences, which appear and disappear in less than 100 femtoseconds in the iodine molecule synchronously with the periodic crossing of two counterpropagating nuclear wave packets. The obtained images have picometer and femtosecond spatiotemporal resolution, representing a detailed picture of the quantum interference.  相似文献   

An insertion/deletion variant of a thymine base in exon 2 of the porcine beta 3‐adrenergic receptor gene associated with loin eye muscle area     

Kensuke HIROSE  Mariko NAKAMURA  Tatsuya TAKIZAWA  Kazuo FUKAWA  Tetsuya ITO  Masayuki UEDA  Takashi SASAKI  Kazuaki TANAKA 《Animal Science Journal》2009,80(6):624-630

An insertion/deletion variant of a thymine base (T5 and T6) in exon 2 of porcine beta 3‐adrenergic receptor (ADRB3) gene has been described. In the current study, we made an association study between the ADRB3 polymorphisms and production traits in 735 Duroc pigs. The allele frequencies for the T5 and T6 alleles in our study population were 0.433 and 0.567, respectively. Any associations between ADRB3 genotype and average daily weight gain during test period, or backfat thickness and intramuscular fat content were not detected in either sex. However the size of the loin eye muscle area (EMA) was significantly associated with ADRB3 genotypes in gilts. T6‐homozygous gilts had a higher mean of EMA (40.6 ± 0.6 cm²) than T5‐homozygous (38.1 ± 0.4 cm², P = 0.002) and heterozygous (38.8 ± 0.3 cm², P = 0.034) gilts. This association was not detected in males. In addition, a multiple traits animal model best linear unbiased predictor (BLUP) analysis revealed that the T6‐homozygous genotype had positive effects on breeding value of EMA. Accordingly, we suggest that ADRB3 polymorphism has the potential to be an important genetic marker for prediction of EMA in Duroc pigs.  相似文献