Autofluorescent substance and neurocyte necrosis in thiamine deficiency in cattle     

T. SHIBAHARA  R. HORINO  T. TANIGUCHI  Y. ANDO 《Australian veterinary journal》1999,77(5):329-330

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Neuronal ceroid-lipofuscinosis in longhaired Chihuahuas: clinical, pathologic, and MRI findings     

Nakamoto Y  Yamato O  Uchida K  Nibe K  Tamura S  Ozawa T  Ueoka N  Nukaya A  Yabuki A  Nakaichi M 《Journal of the American Animal Hospital Association》2011,47(4):e64-e70

Neuronal ceroid-lipofuscinosis (NCL) is a rare group of inherited neurodegenerative lysosomal storage diseases characterized histopathologically by the abnormal accumulation of ceroid- or lipofuscin-like lipopigments in neurons and other cells throughout the body. The present article describes the clinical, pathologic, and magnetic resonance imaging (MRI) findings of the NCL in three longhaired Chihuahuas between 16 mo and 24 mo of age. Clinical signs, including visual defects and behavioral abnormalities, started between 16 mo and 18 mo of age. Cranial MRI findings in all the dogs were characterized by diffuse severe dilation of the cerebral sulci, dilated fissures of diencephalons, midbrain, and cerebellum, and lateral ventricular enlargement, suggesting atrophy of the forebrain. As the most unusual feature, diffuse meningeal thickening was observed over the entire cerebrum, which was strongly enhanced on contrast T1-weighted images. The dogs' conditions progressed until they each died subsequent to continued neurologic deterioration between 23 mo and 24 mo of age. Histopathologically, there was severe to moderate neuronal cell loss with diffuse astrogliosis throughout the brain. The remaining neuronal cells showed intracytoplasmic accumulation of pale to slightly yellow lipopigments mimicking ceroid or lipofuscin. The thickened meninges consisted of the proliferation of connective tissues with abundant collagen fibers and mild infiltration of inflammatory cells suggesting neuroimmune hyperactivity. Although the etiology of this neuroimmune hyperactivity is not currently known, MRI findings such as meningeal thickening may be a useful diagnostic marker of this variant form of canine NCL.  相似文献   

Effect of DNA polymorphisms related to fatty acid composition in adipose tissue of Holstein cattle     

Takahiro NARUKAMI  Shinji SASAZAKI  Kenji OYAMA  Takuya NOGI  Masaaki TANIGUCHI  Hideyuki MANNEN 《Animal Science Journal》2011,82(3):406-411

Fatty acid composition of adipose tissue has been recognized as an important carcass trait because of its relationship with eating quality such as favorable beef flavor and tenderness. Therefore, we investigated the effects of genetic polymorphisms of liver X receptor, alpha (LXR), stearoyl‐CoA desaturase (SCD), Fatty acid synthase (FASN), and Fatty acid binding protein 4 (FABP4) on fatty acid composition in intramuscular fat tissue of Holstein steers. The major allele frequencies were 0.705 in SCD, 0.518 in FABP4, 0.888 in FASN, and 0.984 in LXR. Genotyping of SCD showed significant effect on C14:0, C14:1, C18:0 and saturated fatty acid (P < 0.05). In addition, the result suggested that SCD genotype possibly had effect on composition of C18:1 and monounsaturated fatty acid. Genotype of FABP4 had significant effect on composition of C16:0. Effect of LXR genotypes could not be analyze because of extremely biased genotype frequencies. Our results suggest that genotypes of SCD and FABP4 may in part affect meat quality in Holstein.  相似文献   

Stem necrosis of aster and Russell prairie gentian caused by Chrysanthemum stem necrosis virus     

Kazumi Momonoi  Jouji Moriwaki  Toshiyuki Morikawa 《Journal of General Plant Pathology》2011,77(2):142-146

A new disease causing necrotic streaks on stems and necrosis on leaves of aster (Callistephus chinensis) and Russell prairie gentian (Eustoma grandiflorum) was observed in Toyama Prefecture, Japan, in September 2009. On the bases of host reactions, serological reactions, viral particle morphology, and the nucleotide sequence of the nucleocapsid protein gene, the causal pathogen was identified as Chrysanthemum stem necrosis virus (CSNV). This report is the first in the world of natural infection of aster and Russell prairie gentian by CSNV. We propose the name “stem necrosis of aster and Russell prairie gentian” for these new diseases.  相似文献   

Rat Uterine Oxytocin Receptor and Estrogen Receptor α and β mRNA Levels are Regulated by Estrogen Through Multiple Estrogen Receptors     

Takuya MURATA  Kazumi NARITA  Toru ICHIMARU 《The Journal of reproduction and development》2014,60(1):55-61

Estrogen action is mediated through several types of receptors (ERs), such as ERα, ERβ and putative membrane ERs. Oxytocin receptor (OTR) and ER expression levels in the rat uterus are regulated by estrogen; however, which types of ERs are involved has not been elucidated. This study examined OTR, ERα and ERβ levels in ovariectomized rats treated with 17β-estradiol (E2), an ERα agonist (PPT), an ERβ agonist (DPN) or estren (Es). E2 and PPT increased OTR mRNA levels and decreased ERα and ERβ mRNA levels 3 and 6 h posttreatment. DPN decreased ERα and ERβ mRNA levels at 3 and 6 h, while OTR mRNA levels increased at 3 h and decreased at 6 h. OTR mRNA levels increased 3 h after the Es treatment and then declined until 6 h. ERα and ERβ mRNA levels decreased by 3 h and remained low until 6 h posttreatment with Es. The ER antagonist ICI182,780 (ICI) suppressed the increases in OTR mRNA levels induced 3 h after the Es treatment. However, ICI and tamoxifen (Tam) had no significant effect on ERα and ERβ mRNA levels in the Es-treated or vehicle-treated group. In intact rats, proestrus-associated increases in OTR mRNA levels were antagonized by both ICI and Tam. However, decreases in ERα and ERβ mRNA levels were not antagonized by Tam and ICI, respectively. Therefore, uterine OTR gene expression is upregulated by estrogen through the classical nuclear (or non-nuclear) ERs, ERα and ERβ, while the levels of these ERs are downregulated by estrogen through multiple pathways including Es-sensitive nonclassical ERs.  相似文献   

Detection of ayu sex-linked DNA markers using homologous clones   总被引：2，自引：0，他引：2  

Tomohisa  WATANABE  Kimio  YAMASAKI  Shingo  SEKI  Nobuhiko  TANIGUCHI 《Fisheries Science》2004,70(1):47-52

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Estimating and monitoring the stock size of sandfish <Emphasis Type="Italic">Arctoscopus japonicus</Emphasis> in the northern Sea of Japan     

Kyuji?WatanabeEmail author  Hideki?Sugiyama  Shigeo?Sugishita  Naoki?Suzuki  Kazumi?Sakuramoto 《Fisheries Science》2005,71(4):776-783

ABSTRACT:   The stock size of sandfish in the northern Sea of Japan was estimated by a virtual population analysis (VPA) and sensitivity analyses were attempted on the VPA estimate. The stock size estimates were approximately 600–900 million until 1975, but since 1976 they have rapidly decreased. In the sensitivity analyses, the estimates of absolute stock size were not sensitive against the changes in the fishing mortality coefficient for terminal age and the measurement error in catch-at-age. This suggested that the relative stock size remains almost unaffected by the error in the data used in the VPA, if the degree of catch-at-age error and the natural mortality coefficient is correct. The relationships between the biomass estimated by the VPA and the density index from Danish seine fisheries, and between the biomass and the catch per unit effort (CPUE) from the experimental survey using Danish seine nets, were also examined. The density index and the CPUE indicated significant relations with the biomass. Consequently, the CPUE is useful to monitor the relative stock size in a timely manner, and the VPA estimate and the CPUE should be utilized for adjusting the total allowable catch in the multiseasons.  相似文献   

Models for forecasting sandfish catch in the coastal waters off Akita Prefecture and the evaluation of the effect of a 3-year fishery closure   总被引：1，自引：1，他引：1  

Kazumi Sakuramoto  Hideki Sugiyama  Naoki Suzuki 《Fisheries Science》2001,67(2):203-213

SUMMARY: The sandfish Arctoscopus japonicus in the coastal waters off Akita Prefecture had been landed in amounts of more than 10 000 t continuously from 1963 to 1975. From 1976, however, it began to decrease sharply and fell to only 74 t in 1984. The fishery society of Akita Prefecture closed the fishing from 1 September 1992 to 30 September 1995. Since 1995, the total allowable catch (TAC) allocated in each year has increased. However, the mechanism behind the increment of catch has not been clearly demonstrated. The aim of this study is to elucidate the mechanism behind the increase of catch using catch forecasting models constructed with past water temperature and catch data. The results were as follows: (i) the effect of water temperature in the depth strata 200–300 m, September of year t –1, t –2 and t –3 of station 1 would be important for forecasting the catch in year t; (ii) coastal catch in year t –1 and t –2 would be important for forecasting the catch in year t; (iii) the effect of a fishery closure would be significantly related to the period of the closure and the environmental condition such as water temperature; and (iv) the TAC system would be important for the recovery of stock and to avoid the depletion of abundance.  相似文献   

Survival, growth and gonad development of triploid red sea bream, Pagrus major (Temminck et Schlegel): use of allozyme markers for ploidy and family identification     

K. SUGAMA  N. TANIGUCHI  S. SEKI  H. NABESHIMA 《Aquaculture Research》1992,23(2):149-159

Abstract. Triploidy was induced in three full-sib families of sea bream, Pagrus major (Temminck & Schlegel), by subjecting the fertilized eggs to cold-shock treatment at 0°C for a 12 min duration, starting 3 min after insemination. Results showed that this treatment gave 100% triploid fish with reasonable survival rates of more than 61% up to first feeding, Triploidy induction was proved by the use of allozyme markers at three ( ADH *, EST * and 6PGD *) loci and red blood cell size analysis.
At 2 months of age, the survival of the triploid group was lower than that of the diploids but it was comparable at 10 months. No differences in growth rate between diploid and triploid full-sibs were observed up to the age of 10 months. However, differences in body weight between families were noticed both in diploid and triploid groups when cultured in the same net cage. This possibly suggests a high heritability for the trait examined in the broodstock. The gonads of the triploid fish were significantly smaller than those of the diploids, Histological analysis of the gonads revealed sterility in triploid fish.  相似文献   

First record of Cryptosporidium infection in a raccoon dog (Nyctereutes procyonoides viverrinus)     

Matsubayashi M  Abe N  Takami K  Kimata I  Iseki M  Nakanishi T  Tani H  Sasai K  Baba E 《Veterinary parasitology》2004,120(3):171-175

Cryptosporidium species have been found in more than 150 species of mammals, but there has been no report in raccoon dogs. Here we found the Cryptosporidium organism in a raccoon dog, Nyctereutes procyonoides viverrinus, and identified this isolate using PCR-based diagnostic methods. Cryptosporidium diagnostic fragments of the 18S ribosomal RNA, Cryptosporidium oocyst wall protein and 70-kDa heat shock protein genes were amplified from the isolate and sequenced to reveal the phylogenetic relationships between it and other Cryptosporidium species or genotypes reported previously. The results showed that the raccoon dog isolate represented the C. parvum cattle genotype which could be a causative agent in human cryptosporidiosis.  相似文献