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141.
A manual, ultrasound-guided biopsy technique was compared to a new automatic method using a new biopsy device. The liver and the left kidney of 10 dogs were biopsied using the two methods. The specimens from the biopsies were compared for size and quality. Results demonstrate that larger and higher quality samples were obtained with the new automatic method.  相似文献   
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Outer membrane-peptidoglycan complex from Brucella abortus was separated from cytoplasmic membrane and cytosol by either sucrose density gradient fractionation or differential (rate) centrifugation of surface labeled cells disrupted by sonication without the use of detergents. The outer membrane-peptidoglycan complex had a buoyant density of 1.22 gm/ml and contained 67 labeled SDS-soluble proteins when examined by SDS-PAGE. Included were four major bands exhibiting molecular masses of 88k, 40k, 35.7k and 26k daltons corresponding to previously described group 1, 2 and 3 outer membrane proteins. Lysozyme treatment of outer membrane-peptidoglycan complex increased its buoyant density to 1.25 gm/ml and released eight additional peptidoglycan-linked proteins.  相似文献   
145.
A foal born 3 weeks prematurely was treated for respiratory distress, using a combination of oxygen therapy and mechanical ventilatory assistance. Clinical response and arterial blood gas tensions were monitored regularly. Continuous positive-airway pressure and intermittent positive-pressure ventilation administered via a nasotracheal tube were effective in improving arterial oxygenation and ventilatory function.  相似文献   
146.
SUMMARY A 19-month-old pony gelding was presented with chronic renal failure, after deteriorating progressively during the preceding 3 months. There was pronounced azotaemia, hyponatraemia and hypochloraemia, but plasma calcium and phosphorus levels were normal. At autopsy both kidneys were small and nodular and were characterised by collapsed segments of cortex and medulla interspersed with areas of pale tissue. The latter showed glomerular immaturity associated with a range of degenerative processes involving the glomeruli and tubules. The condition bore many similarities to that of renal cortical dysplasia in other species.  相似文献   
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Six healthy adult mares were given a single IV injection of trimethoprim (TMP)-sulfadiazine (SDZ) at a dosage rate of 2.5 mg of TMP/kg of body weight and 12.5 mg of SDZ/kg. Serum, synovial, peritoneal, and urine TMP-SDZ concentrations were measured serially over a 48-hour period. The highest measured mean concentrations of TMP and SDZ were found in the first (0.5 hour) sample of serum, synovial fluid, and peritoneal fluid. The mean peak concentrations of TMP and SDZ averaged 4.37 micrograms/ml and 21.81 micrograms/ml for serum, 2.95 micrograms/ml and 15.31 micrograms/ml for synovial fluid, and 3.88 micrograms/ml and 19.52 micrograms/ml for peritoneal fluid, respectively. Urine concentrations of the drugs were relatively high and peaked early. The elimination rate for TMP and SDZ averaged 0.41 and 0.26 hour-1, while the elimination half-life was 1.91 and 2.71 hours, respectively, and the volume of distribution averaged 0.59 and 0.52 L/kg, respectively.  相似文献   
149.
Two adult male labrador dogs had short clinical histories of congestive cardiac failure lasting only six weeks. Cardiac function deteriorated rapidly in both dogs, in spite of symptomatic treatment with cardiac glycoside, diuretic and p-adrenergic blocker. Necropsies revealed ascites and pulmonary congestion, but no macroscopic evidence of valvular or myocardial disease adequate to account for the cardiac dysfunction. Both dogs had extensive stenosis of extramural coronary arteries. This unusual vascular lesion comprised fibroelastic intimal thickening, discontinuity of internal elastic lamella and focal atrophy of medial smooth muscle. It seems likely that cardiac failure in these dogs was associated with myocardial underperfusion caused by extensive non-thrombotic, non-atherogenic stenosis of extramural coronary arteries.  相似文献   
150.
A four-year-old shire mare with haematuria, colic, terminal weight loss and an abdominal mass had a large unilateral renal adenocarcinoma. Clinical signs were monitored for 11 months. Increased serum copper concentrations were measured on two occasions. Hypercupraemia is discussed as a possible paraneoplastic change.  相似文献   
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