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31.
Kensuke Hirose Satoshi Mikawa Naohiko Okumura Go Noguchi Kazuo Fukawa Naoe Kanaya Ayumi Mikawa Aisaku Arakawa Tetsuya Ito Yoichi Hayashi Fumio Tachibana Takashi Awata 《Animal Science Journal》2013,84(3):213-221
Vertnin (VRTN) is involved in the variation of vertebral number in pigs and it is located on Sus scrofa chromosome 7. Vertebral number is related to body size in pigs, and many reports have suggested presence of an association between body length (BL) and meat production traits. Therefore, we analyzed the relationship between the VRTN genotype and the production and body composition traits in purebred Duroc pigs. Intramuscular fat content (IMF) in the Longissimus muscle was significantly associated with the VRTN genotype. The mean IMF of individuals with the wild‐type genotype (Wt/Wt) (5.22%) was greater than that of individuals with the Wt/Q (4.99%) and Q/Q genotypes (4.79%). In addition, a best linear unbiased predictor of multiple traits animal model showed that the Wt allele had a positive effect on the IMF breeding value. No associations were observed between the VRTN genotype and other production traits. The VRTN genotype was related to BL. The Q/Q genotype individuals (100.0 cm) were longer than individuals with the Wt/Q (99.5 cm) and Wt/Wt genotypes (98.9 cm). These results suggest that in addition to the maintenance of an appropriate backfat thickness value, VRTN has the potential to act as a genetic marker of IMF. 相似文献
32.
Sequence variation of the mitochondrial DNA was analyzed to examine the genetic structure and demographic history of the goldlined
spinefoot Siganus guttatus in the northwestern Pacific. In total, 451 nucleotide sequences spanning from the tRNAThr gene to the middle of the control region were determined from 254 specimens collected from five localities; three in the
Ryukyu Islands (Okinawa, Miyako, and Ishigaki Islands), Taiwan, and Cebu Island of the Philippines; 73 variable sites and
75 haplotypes were detected. Our results showed restricted gene flow and genetic differentiation among all populations, with
the exception of genetic homogeneity between the Miyako and Ishigaki populations; that is, this species will be able to cross
between Miyako and Ishigaki (ca. 120 km) by the transport of pelagic larvae, and gene flow between Okinawa and Miyako/Ishigaki
Islands (ca. 330–450 km) is restricted. A non-dispersal strategy will lead to restricted gene flow and genetic structuring
in S. guttatus. Both the neutrality tests and the mismatch distribution indicated that S. guttatus might have been in populations at demographic equilibrium. This suggests that population range expansion may have been restricted
owing to a non-dispersal strategy that may have restrained S. guttatus from demographic expansion after glaciation. The result will be of fundamental importance for resource management of this
species. 相似文献
33.
Yuta NISHIYAMA Yasuhiro FUKUYAMA Takuya MARUO Shinichiro YODA Masataka IWANO Shinpei KAWARAI Hideki KAYANUMA Kensuke ORITO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(8):1206
Tegafur is a prodrug of fluoropyrimidine 5-fluorouracil (5-FU), while TS-1TM is an oral fixed-dose combination of three active drugs, tegafur, gimeracil, and oteracil. This pilot study evaluated the safety of tegafur/gimeracil/oteracil in the treatment of cancers in dogs. Tegafur/gimeracil/oteracil was administered orally at a mean dose of 1.1 mg/kg twice daily on alternate days, Monday-Wednesday-Friday, every week to 11 dogs with tumors. Partial response and stable disease were observed in one dog each, whereas six exhibited progressive disease. Three dogs were not assessed. Adverse events, the most serious being grade 2, were noted in seven dogs. Adverse events were acceptable, and the drug was effective in some dogs. Therefore, tegafur/gimeracil/oteracil may be useful for treating malignant solid tumors in canines. 相似文献
34.
Toshiho Nishita Daisuke Yorifuji Kensuke Orito Nobutsune Ichihara Kazuyoshi Arishima 《Acta veterinaria Scandinavica》2012,54(1):34
Background
The levels and immunohistochemical localization of muscle carbonic anhydrase III (CA-III) in healthy chickens and in muscular dystrophia affected (DA) chickens show that the muscles of diseased animal undergo a progressive increase of enzyme activity.Methods
An enzyme-linked immunoassay was used to assess the CA-III levels in the muscles and other tissues from eight normal White Leghorn chickens and in two chickens with muscular dystrophy. Immunohistochemical localization of the enzyme in the muscles of these animals was also determined.Results
The levels of CA-III in the tensor fasciae latae and the superficial pectoral muscles of the DA chickens were higher than the level in normal chickens. The concentrations of CA-III in erythrocytes and plasma from diseased chickens were approximately 15-fold and 1.4-fold higher than in the normal chickens, respectively. In the superficial pectoral and the tensor fasciae latae muscles of diseased chickens, the numbers of strongly stained and weakly stained fibers were greater than that in the normal chickens.Conclusion
The levels of CA-III in the superficial pectoral muscle, the tensor fasciae latae muscle, plasma and erythrocytes from the chickens with muscular dystrophy were higher than found in normal chickens. 相似文献35.
To clarify the interaction between St John's wort (SJW) and cyclosporine (CsA) in dogs, the pharmacokinetics of CsA before and during the repeated administration of SJW were analyzed. In the SJW group, SJW (300 mg) was given orally to four dogs every 24 h for 14 days. A single dose of CsA (5 mg/kg) was given orally 7 days before and 7 and 14 days after the initiation of the repeated administration of SJW. In the Control group, a single dose of CsA (5 mg/kg) was given orally to four other dogs in accordance with that in the SJW group. Blood samples from both groups were collected, and whole-blood concentrations of CsA were determined using high-performance liquid chromatography with UV detection. The maximum whole-blood concentration and AUC(0-∞) of the SJW group were significantly lower and the CL(tot) /F and V(d) /F were significantly higher than those in the Control group 7 and 14 days after the initiation of repeated SJW. Thus, repeated administrations of SJW affect the pharmacokinetic profiles of CsA in dogs. Further studies are necessary to elucidate the mechanisms of interaction between SJW and CsA in dogs. 相似文献
36.
Ikeura Hiroshi Phongchanmixay Sengthong Chomxaythong Amphone Matsumoto Naruo Kawamura Kensuke Homsengchanh Laeh Inkhamseng Somphone 《Paddy and Water Environment》2019,17(2):121-130
Paddy and Water Environment - Irrigated areas in the Lao People’s Democratic Republic (Laos) constitute only 12% of the total agricultural land. Most of the lowland rice is cultivated under... 相似文献
37.
Phongchanmixay Sengthong Bounyavong Bounson Khanthavong Phanthasin Khanthavong Thanouphone Ikeura Hiroshi Matsumoto Naruo Kawamura Kensuke 《Paddy and Water Environment》2019,17(2):91-99
Paddy and Water Environment - Savannakhet Province has 25% of the total lowland rice cultivation area of Lao People’s Democratic Republic (Laos). However, most of the fields are rainfed, with... 相似文献
38.
Yoshinobu UEMOTO Shuji SATO Chika OHNISHI Kensuke HIROSE Kenji KAMEYAMA Kazuo FUKAWA Osamu KUDO Eiji KOBAYASHI 《Animal Science Journal》2010,81(1):28-33
Leg weakness in pigs is a serious problem in the pig industry. We performed a whole genome quantitative trait locus (QTL) analysis to find QTLs affecting leg weakness traits in the Landrace population. Half-sib progeny ( n = 522) with five sires were measured for leg weakness traits. Whole genome QTL mapping was performed using a half-sib regression-based method using 190 microsatellite markers. No experiment-wide significant QTLs affecting leg weakness traits were detected. However, at the 5% chromosome-wide level, QTLs affecting leg weakness traits were detected on chromosomes 1, 3, 10 and 11 with QTL effects ranging from 0.07 to 0.11 of the phenotypic variance. At the 1% chromosome-wide level, QTLs affecting rear feet score and total leg score were detected on chromosomes 2 and 3 with QTL effects of 0.11 and 0.13 of the phenotypic variance, respectively. On chromosome 3 and 10, some QTLs found in this study were located at nearby positions. The present study is one of the first reports of QTLs affecting fitness related traits such as leg weakness traits, that segregate within the Landrace population. The study also provides useful information for studying QTLs in purebred populations. 相似文献
39.
Available organic nitrogen in temperate, subtropical, and tropical soils extracted with different solutions 总被引：1，自引：0，他引：1
Extraction of organic N by chemical solutions has been used to assess the amount of available N in soil. We tested the efficiency
of several solutions in extracting organic N from tropical, subtropical and temperate soils. A conventional 0.067 M phosphate
buffer successfully extracted organic N from all 23 soils examined. High-performance size exclusion chromatograms showed a
single peak at about 7,800 Da for all phosphate buffer extracts irrespective of soil types. The peak area correlated with
the organic N concentration of extracts. Tropical soils had lower retention of organic N than other soils according to the
conventional and sequential extraction with phosphate buffer. Organic N extracted with sulfuric acid was significantly (P < 0.001) correlated with the amount of extracted Fe, suggesting that Fe might play a role in the retention of organic N in
soil. 相似文献
40.
Kensuke?Eiki Masayuki?Satake Kazuhiko?Koike Takehiko?Ogata Tadashi?Mitsuya Yasukatsu?OshimaEmail author 《Fisheries Science》2005,71(3):633-638
ABSTRACT: Yessotoxin (YTX) is a shellfish toxin and its contamination in bivalves has seriously damaged shellfish industries. The biogenetic origin of YTX was identified as the dinoflagellate Protoceratium reticulatum (Claparède et Lachmann) Bütschli collected in New Zealand and Yamada Bay, Iwate in Japan. Scallops cultured in Mutsu Bay, Japan, were frequently contaminated with YTX, however, occurrence of P. reticulatum in this bay and YTX production by the local strains have not been investigated. Eight strains of P. reticulatum , isolated from the bay, were cultured in the laboratory, and analyzed by fluorometric high-pressure liquid chromatography and liquid chromatography/mass spectrometry methods for YTX production and composition. All strains tested were confirmed to produce YTX, and none of them produced known YTX analogs. Toxin amount and composition differed from strain to strain. This result is also confirmation of one of the biogenetic origins of YTX in Mutsu Bay. 相似文献