Reproduction in Javanese sheep: evidence for a gene with large effect on ovulation rate and litter size   总被引：2，自引：0，他引：2  

G E Bradford  J F Quirke  P Sitorus  I Inounu  B Tiesnamurti  F L Bell  I C Fletcher  D T Torell 《Journal of animal science》1986,63(2):418-431

Three breeds of Javanese sheep are described briefly and data suggesting the segregation of a gene with large effect on ovulation rate and litter size are presented. The three breeds are Javanese Thin Tail (JTT), Javanese Fat Tail (JFT) and Semarang (SEM), the last possibly a substrain of JTT. All three breeds have mean mature ewe weights under 30 kg. Ovulation rate and litter size did not differ significantly among the three; all had litter sizes of up to 4 or 5 with a mean for mature ewes of approximately 2. Ovulation rate ranged from 1 to 5 and had an average within-breed repeatability of .8 within season and .65 between seasons. Within-breed repeatability of litter size was .35 +/- .06. Prenatal survival in pregnant ewes with two, three and four or more ovulations averaged 93, 88 and 86% over two seasons. Dams that had at least one ovulation rate or litter size record greater than or equal to 3 produced two groups of daughters in approximately equal numbers: one group with many records greater than or equal to 3 and mean ovulation rate and litter size of 2.73 and 2.31, respectively, and one group with ovulation rates and litter sizes of 1 or 2 and corresponding means of 1.39 and 1.38. Dams with ovulation rate or litter size records of only 1 or 2 produced daughters in which over 90% had records of only 1 or 2. Estimated heritabilities for the mean of approximately three ovulation rate or litter size records from these daughter-dam comparisons exceeded .7. These results suggest segregation of a Booroola-type gene, one copy of which increases ovulation rate by about 1.3 and litter size by .9 to 1.0. Relationships between duration of estrus and ovulation rate, and between timing of release of luteinizing hormone and number of eggs shed, resemble the pattern in Booroola Merino more closely than that in Finnish Landrace or Romanov, supporting the hypothesis of a major gene.  相似文献   

Subcutaneous clostridial infection in broilers   总被引：2，自引：0，他引：2  

C L Hofacre  J D French  R K Page  O J Fletcher 《Avian diseases》1986,30(3):620-622

A flock of 12,500 broilers 36 days of age experienced a sudden increase in mortality. Post-mortem lesions were emphysema, severe enteritis, and a serosanguineous fluid in the subcutaneous tissue of the breast and thighs; there was no evidence of a loss in the integrity of the skin. Clostridium perfringens and C. septicum were isolated from the affected subcutaneous tissue. Histopathological and serological examination indicated previous infection with infectious bursal disease virus. The subsequent immunosuppression and severe enteritis may have permitted the clostridia access to the circulatory system, with localization in the subcutaneous areas of the breast and thighs. Mortality returned to normal 48 hours after potassium penicillin G was administered via the drinking water.  相似文献   

Pilot study of Australian veterinarians and their perceptions and experiences related to online pet health information     

LR Kogan  JA Oxley  SJ Hazel 《Australian veterinary journal》2019,97(1-2):10-13

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Hospital‐acquired Anemia in Critically Ill Dogs and Cats: A Multi‐Institutional Study          下载免费PDF全文

A.M. Lynch  M. Respess  A.E. Boll  M. Bozych  M. McMichael  D.J. Fletcher  A.M. De Laforcade  E.A. Rozanski 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(1):141-146

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Hypersomatotropism in 3 Cats without Concurrent Diabetes Mellitus          下载免费PDF全文

J.M. Fletcher  C.J. Scudder  M. Kiupel  H.N. Pipe‐Martin  P.J. Kenny  P. Mantis  J. Fenn  K. Smith  R.V. Blair  L.A. Granger  S.J.M. Niessen 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(4):1216-1221

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Assessment of the relationships among coagulopathy,hyperfibrinolysis, plasma lactate,and protein C in dogs with spontaneous hemoperitoneum          下载免费PDF全文

Daniel J. Fletcher PhD  DVM  DACVECC  Elizabeth A. Rozanski DVM  DACVIM  DACVECC  Benjamin M. Brainard VMD  DACVA  DACVECC  Armelle M. de Laforcade DVM  DACVECC  Marjory B. Brooks DVM  DACVIM 《Journal of Veterinary Emergency and Critical Care》2016,26(1):41-51

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Space shuttle development     

Fletcher JC 《Science (New York, N.Y.)》1986,233(4761):263

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Effect of body condition score and reuse of progesterone‐releasing intravaginal devices on conception rate following timed artificial insemination in Nelore cows          下载免费PDF全文

LL Pereira  AP Ferreira  WG Vale  LR Serique  KAL Neves  AC Morini  BM Monteiro  AHH Minervino 《Reproduction in domestic animals》2018,53(3):624-628

This study had the aim of investigating the efficiency of timed artificial insemination (TAI) through the progesterone‐releasing intravaginal device (PRID), used in new condition and for the second and third times in Nelore cows. The effects of device reuse and body condition score (BCS) on the conception rate (CR) were evaluated in 1,122 multiparous Nelore cows (mean BCS of 2.7 ± 0.4), which were randomly distributed into three groups that received new (n = 330), once (n = 439) and twice used (n = 353) PRID. Among the 1,122 females that underwent TAI, 573 became pregnant, thus representing an overall CR of 51.06%. Cows with BCS between 2.75 and 4.0 had greater (p < .0001) CR (69.75%) than cows with BSC of 2.0–2.5 (32.98%). It was observed that the CR through using PRID was 60.00%, 51.71% and 41.93% for new, once and twice used PRID, respectively, with difference between all groups (p < .0001). Under tropical conditions, animals with BCS greater than 2.5 had a higher CR, and the CR decreased proportionally with the number of times that the PRID had been used.  相似文献   

Antimicrobial delivery by intrasynovial catheterisation with systemic administration for equine synovial trauma and sepsis     

AA Stewart  LR Goodrich  CR Byron  RB Evans  MC Stewart 《Australian veterinary journal》2010,88(4):115-123

Objective To present the technique for intra-articular catheter placement and report the clinical outcomes of 38 cases of equine synovial trauma and/or infection treated with broad-spectrum antimicrobials administered via an intrasynovial catheter (ISC). Design Retrospective study. Procedure Medical records of 38 horses treated for synovial trauma and sepsis with frequent antimicrobial administration through an ISC from 1995 to 2008 were reviewed. Follow-up information was obtained via clinical re-evaluation or telephone contact with the owners. Results The majority of horses (84%) received amikacin and Timentin® four times daily. In addition, synovial lavage through the ISC was carried out in 27 horses (71%). Only radiological evidence of osteolysis had a significant negative impact on both lameness at the time of hospital discharge and the long-term outcome. In total, 92% of horses treated with frequent antimicrobial administration through an ISC had clinical resolution of infection. Catheter obstruction occurred in three cases, necessitating replacement or removal, and two synovial fistulae developed at sites of open drainage. The majority of horses treated had a favourable outcome, with 86% being at least pasture sound and 43% returned to riding. Conclusion Septic synovial structures treated with frequent antimicrobial administration through an ISC had a good prognosis for survival and 43% returned to riding, which is consistent with the results of other studies. The use of a simple ISC should be considered when broad-spectrum intrasynovial antimicrobial administration and lavage of a septic synovial structure are indicated.  相似文献   

Cassini ion and neutral mass spectrometer: Enceladus plume composition and structure     

Waite JH  Combi MR  Ip WH  Cravens TE  McNutt RL  Kasprzak W  Yelle R  Luhmann J  Niemann H  Gell D  Magee B  Fletcher G  Lunine J  Tseng WL 《Science (New York, N.Y.)》2006,311(5766):1419-1422

The Cassini spacecraft passed within 168.2 kilometers of the surface above the southern hemisphere at 19:55:22 universal time coordinated on 14 July 2005 during its closest approach to Enceladus. Before and after this time, a substantial atmospheric plume and coma were observed, detectable in the Ion and Neutral Mass Spectrometer (INMS) data set out to a distance of over 4000 kilometers from Enceladus. INMS data indicate that the atmospheric plume and coma are dominated by water, with significant amounts of carbon dioxide, an unidentified species with a mass-to-charge ratio of 28 daltons (either carbon monoxide or molecular nitrogen), and methane. Trace quantities (<1%) of acetylene and propane also appear to be present. Ammonia is present at a level that does not exceed 0.5%. The radial and angular distributions of the gas density near the closest approach, as well as other independent evidence, suggest a significant contribution to the plume from a source centered near the south polar cap, as distinct from a separately measured more uniform and possibly global source observed on the outbound leg of the flyby.  相似文献