Activation of Master Autophagy Regulator TFEB During Systemic LPS Administration in the Cornea     

Kyoko Uchida  Kana Unuma  Takeshi Funakoshi  Toshihiko Aki  Koichi Uemura 《Journal of toxicologic pathology》2014,27(2):153-158

  相似文献   

Salinity tolerance of non‐native suckermouth armoured catfish (Loricariidae: Pterygoplichthys) in south‐eastern Mexico: implications for invasion and dispersal     

Krista A. Capps  Leo G. Nico  Manuel Mendoza‐Carranza  Wendi Arévalo‐Frías  Andrew J. Ropicki  Sebastian A. Heilpern  Rocío Rodiles‐Hernández 《水产资源保护:海洋与淡水生态系统》2011,21(6):528-540

Optimal Tension,Position, and Number of Prostheses Required for Maximum Rima Glottidis Area After Laryngoplasty     

Andrea S. Bischofberger Dr Med Vet  Marta M. Wereszka BVSc Dip ACVS  Ines Hadidane  Nigel R. Perkins BVSc  PhD  Dip ACT  Leo B. Jeffcott MA  BVetMed  PhD  DVSc  FRCVS  Andrew J. Dart BVSc  PhD  Dip ACVS & ECVS 《Veterinary surgery : VS》2013,42(3):280-285

  相似文献   

Sorption of metal ions from aqueous solution to spruce bark     

Pingping Su  Kim Granholm  Andrey Pranovich  Leo Harju  Bjarne Holmbom  Ari Ivaska 《Wood Science and Technology》2013,47(5):1083-1097

The concentrations and protonation constants of the functional groups like carboxyl and phenolic hydroxyl groups in spruce bark were determined by a potentiometric acid–base titration method. The non-cellulosic carbohydrates in spruce bark were also characterized by acid methanolysis and GC, including determination of the uronic acid units, which are the key units involved in metal sorption. Sorption of metal ions to bark takes place by ion exchange, mainly by complexation to these functional groups. The sorption equilibrium time, studied by using a batch method, was approximately 5 min. The metal sorption capacity of spruce bark and the affinity order of metal ions were studied with four different metal ion mixtures using a column chromatographic method. Because a method of competition was used, concentration of metal ions adsorbed to bark depends on the metal ions present in the mixtures studied. In the sorption experiments with same metal ion mixtures, inner bark of spruce exhibited higher sorption capacity than outer bark. By combination of the results from several experiments, the following affinity order was obtained Fe³⁺ ? Pb²⁺ ? Cu²⁺ ? Cd²⁺ > Zn²⁺ > Ni²⁺ > Ba²⁺ > Ca²⁺ > Sr²⁺ > Mn²⁺ > Mg²⁺ ? K⁺ ~ Na⁺ ~ Li⁺. Bark has a great potential as an effective and inexpensive sorbent for removal of metal ions from, e.g., waste water.  相似文献   

The content of Hb in the blood and of different constituents in the plasma of lambs with low and normal increase in body mass]     

T van Dich  E Kolb  M Leo  M Ulbrich  W Süss 《Tier?rztliche Praxis》1992,20(6):585-593

In lambs with a very restricted intake of nutrients and an increase of the body mass of less than 60 g per day (group A) and in those with an increase of more than 220 g/day (group B), analyses of components of the blood and the plasma were performed at certain intervals. In the lambs of group A an anemia developed in the course of 77 days. The concentrations of alpha-amino-N, non-protein-N, urea, glucose and insulin as well as the activity of the alkaline phosphatase of the plasma of the lambs of group A were always lower than those of group B. The beta-hydroxybutyrate concentration of the lambs of group A on the 7th and 21st day of the experiment was higher than that of group B. The concentrations of inorganic phosphate and iron in the plasma of group A at most points during the study were lower than that in group B.  相似文献   

The hemoglobin content and hematocrit value of the blood and levels of Fe, Fe-binding capacity and copper in the blood plasma of sows and piglets upon supplementary feeding of FeSO4 to lactating sows     

E Kolb  U Hofmann  M Leo  H Dittrich  G Gründel  K Nestler  C Schineff  U Schmidt 《Archiv fuer experimentelle veterinaermedizin》1987,41(1):28-36

  相似文献   

In vivo effects of the fungicide ethaboxam on microtubule integrity in Phytophthora infestans     

Uchida M  Roberson RW  Chun SJ  Kim DS 《Pest management science》2005,61(8):787-792

The effects of ethaboxam (LGC-30473), a novel thiazole carboxamide, on microtubule organization was investigated in Phytophthora infestans (Mont) de Bary (Oomycota) at the light microscope level using standard immunofluorescence and laser scanning confocal microscopy. Hyphal cells were exposed to various concentrations ranging from 0.01 to 1.0 microg ml(-1) of ethaboxam at incubation times of 30, 60 and 120 min. Microtubules were disrupted after exposure to ethaboxam for 30 min at 0.01 microg ml(-1). Similar experimental conditions were used to document the effects of ethaboxam on microtubule integrity in the model fungus Aspergillus nidulans (Eidam) Winter (Ascomycota) and in mammalian mouse 17 clone 1 cells. Under these conditions, there was no evidence to suggest that microtubules in A. nidulans and mouse culture cells were affected by the ethaboxam. These results indicate that ethaboxam is specific for the targeting of microtubule disruption in P. infestans.  相似文献   

Pathogenesis and phylogenetic analyses of canine distemper virus strain 007Lm, a new isolate in dogs   总被引：5，自引：0，他引：5  

Lan NT  Yamaguchi R  Furuya Y  Inomata A  Ngamkala S  Naganobu K  Kai K  Mochizuki M  Kobayashi Y  Uchida K  Tateyama S 《Veterinary microbiology》2005,110(3-4):197-207

  相似文献   

Hematological findings and antibody responses in Syrian hamster (Mesocricetus auratus) infected with Babesia microti     

Ike K  Takeuchi K  Uchida Y  Imai S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(4):457-460

Hematological findings during the course of infection and the antibody response in Syrian hamsters infected with Babesia microti were examined. A macrocytic hypochromic anemia with an increase of the reticulocyte count was detected as a rise in the parasitized erythrocyte rate. White blood cell counts also remarkedly increased with the increases of both neutrophils and active-shaped monocytes, and thus they particularly play an important role in eliminating the parasite. In Western blotting with the sera from the hamsters infected with B. microti, a 38 kDa protozoan antigen reacted to the early-term sera, and additionally 28, 32, and 34 kDa antigens also reacted to the medium- and latter-term, and convalescent sera. These antigens were immunodominant and the antibodies against these antigens had also important roles for inhibition of this parasite.  相似文献   

A neurological disease with spongy degeneration in a newborn Japanese black calf     

Kato K  Uchida K  Murakami T  Tateyama S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(10):1067-1070

A Japanese Black calf, 3 day-old male, showed severe ataxia, lateral recumbency, and opisthotonos at the birth. Histopathological examinations revealed severe status spongiosis throughout the central nervous system. Numerous vacuoles within the neuropile varying in size and shape were observed in both formalin-fixed paraffin and cryostat sections. In the lesions, a limited number of spheroids and macrophages were observed within the myelin sheaths with very mild astrogliosis. These vacuoles were negative for both periodic acid Schiff and Sudan black stains. The clinical and histopathological features were almost in conformity with those of bovine maple syrup urine disease (MSUD). Although we could not confirm completely the etiology, congenital hereditary neurological diseases including MSUD are considerable as the possible disease entry in the present case.  相似文献