Serological changes observed in horses infected with Anoplocephala perfoliata after treatment with praziquantel and natural reinfection     

Abbott JB  Mellor DJ  Barrett EJ  Proudman CJ  Love S 《The Veterinary record》2008,162(2):50-53

The serological changes in two groups of horses known to be harbouring Anoplocephala perfoliata were studied; 12 were treated with 1.5 mg/kg praziquantel and 200 microg/kg ivermectin, and 14 were treated with 200 microg/kg ivermectin. Serological and faecal analyses were carried out on each animal at intervals for 758 days. The titres of antibodies specific for A perfoliata decreased from the day of treatment to day 28 in both groups, and continued to decrease in the group treated with praziquantel and ivermectin, with the first significant decrease from the other group at day 121. From day 151 to day 295 the first significant increase in antibody levels in the group treated with both drugs was observed; no A perfoliata eggs were detected in the faeces of these animals until day 295 when five of the 10 were positive.  相似文献   

Immunoglobulin G4‐related disease in a dog     

Lydia J. Colopy  Kai‐Biu Shiu  Laura A. Snyder  Anne C. Avery  Emily D. Rout  A R. Moore 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(6):2732-2738

Immunoglobulin G4‐related disease (IgG4‐RD), which affects many organ systems, has been recognized as a distinct clinical entity in human medicine for just over a decade but has not been previously identified in dogs. In humans, IgG4‐RD is characterized by diffuse IgG4‐positive lymphoplasmacytic infiltrates that commonly lead to increased serum concentrations of IgG4 and IgE, peripheral eosinophilia, tumorous swellings that often include the parotid salivary glands, obliterative phlebitis, and extensive fibrosis. Herein we describe the diagnosis, clinical progression, and successful treatment of IgG4‐RD in an 8‐year‐old female spayed Husky mixed breed dog. Immunoglobulin G4‐related disease should be considered as a differential diagnosis for dogs with vague clinical signs, lymphoplasmacytic swellings, restricted polyclonal gammopathy, eosinophilia or some combination of these findings.  相似文献   

Alternatives in Donkey semen cryopreservation: Mare vs. Jenny Colostrum     

Cristina lvarez  Noelia Gonzlez  Victoria Luo  Felisa Martínez  Lydia Gil 《Reproduction in domestic animals》2019,54(Z4):94-97

The aim of this study was to test and compare two new components in extenders for freezing donkey semen: mare colostrum and jenny colostrum. Colostrum was obtained from four mares and four jennies right after the foal's birth. Ejaculates were collected from five fertile donkeys. Sperm samples were pooled, diluted and cryopreserved in three different experimental extender groups: lactose supplemented with egg yolk extender (20%) as the control group, lactose supplemented with jenny colostrum extender (20%), and lactose supplemented with mare colostrum extender (20%). After thawing, we evaluated the sperm motility by means of computer‐assisted analysis, viability by SYBR‐14 and propidium iodide (PI), membrane functional by HOS test and acrosome integrity by isothiocyanate conjugated with peanut agglutinin (FITC‐PNA) and PI. The results demonstrated that lactose–jenny colostrum extender displayed significantly higher values (p < .05) in nearly all parameters evaluated – Total Motility, Viability, HOS test, VCL, VSL, VAP, LIN, STR and WOB –, compared with mare colostrum and egg yolk extenders after thawing. In conclusion, the extender containing jenny colostrum used for donkey semen cryopreservation improved the donkey sperm quality after the freezing–thawing process.  相似文献   

Mermithid nematode infection in a colony of blue-winged grasshoppers (Tropidacris collaris)     

Lydia M Attard  Ramon A Carreno  Jean A Paré  Andrew S Peregrine  Christopher J Dutton  Thomas R Mason 《Journal of zoo and wildlife medicine》2008,39(3):488-492

A die-off occurred in a captive colony of blue-winged grasshoppers (Tropidacris collaris) at the Toronto Zoo. One fourth of the colony died within a year due to infection with worms initially mistaken for nematomorphs but later identified as nematodes belonging to the Mermithidae, genus Mermis. Mortality persisted and the grasshopper population dwindled over the following years. Mermithid larvae developed in the hemocoel of the insects until they eventually emerged from a hollowed-out exoskeleton. Circumstantial evidence suggests that the parasites were introduced with raspberry browse that was grown on site and contaminated with mermithid eggs.  相似文献   

CLINICAL,DIAGNOSTIC, AND PATHOLOGICAL FEATURES OF 2 CASES OF METASTATIC IRIDOPHOROMA IN A VEILED CHAMELEON (CHAMAELEO CALYPTRATUS) AND A RED-BARRED DRAGON (CTENOPHORUS VADNAPPA)     

Lydia J. Tong  Whitney Ong  Frances Hulst  Gabrielle Tobias  Kimberly Vinette Herrin  Larry Vogelnest 《Journal of Exotic Pet Medicine》2018,27(4):53-60

Iridophores are iridescent cutaneous pigment cells found in reptiles, fish, and amphibians. Neoplasms of iridophores are rarely reported, and little is known about their behaviour, metastatic potential, and prognostic indicators. This paper reports details of the clinical course and pathological findings of metastatic iridophoroma in a veiled chameleon (Chamaeleo calyptratus) and red-barred dragon (Ctenophorus vadnappa). The veiled chameleon presented with a subcutaneous mass on the right lateral elbow and was diagnosed as an iridophoroma on fine needle aspiration. It was otherwise clinically normal. Within 35 days of excision, multiple secondary skin masses developed which were often non-pigmented and required microscopic examination to identify them as iridophoroma metastases. There were in total 54 days between the first detection of the primary mass and end stage, extensive cutaneous and visceral metastatic disease, and there had been no detectable primary mass during routine clinical examination 128 days prior to death. The red-barred dragon presented with a white sub-mandibular mass. While undergoing an excisional biopsy the animal expired, post-mortem examination revealed a cutaneous malignant iridophoroma with tumour cell clusters seen in pulmonary arterial vessels, suggesting that surgical handling of iridophoroma could precipitate the release of circulating tumour cell clusters. This is the first iridophoroma described in a red-barred dragon and the second report of a malignant iridophoroma in a veiled chameleon. Timely detection and careful excision of lizard iridophoroma may be an important factor in clinical outcome.  相似文献   

Re-challenge of pigs following recovery from proliferative enteropathy     

Collins AM  Love RJ 《Veterinary microbiology》2007,120(3-4):381-386

An experimental challenge model was developed to demonstrate Lawsonia intracellularis colonization and reproduction of proliferative enteropathy (PE) in naïve weaner pigs. Groups of pigs were orally dosed with between 10¹⁰ and 10⁵ L. intracellularis extracted from haemorrhagic PE affected mucosa. Pigs were monitored for clinical signs and intestinal lesions of PE and evidence of bacterial colonization by serology and faecal polymerase chain reaction (PCR). One group of challenged pigs were necropsied after 21 days to confirm the reproduction of PE. L. intracellularis colonization and seroconversion was delayed in pigs dosed with lower numbers of L. intracellularis. When faecal shedding of L. intracellularis ceased to be detected in all of the challenged pigs, they were re-dosed orally with approximately 10¹⁰ L. intracellularis and monitored for evidence of re-colonization and clinical disease. This study demonstrated that pigs previously challenged with L. intracellularis were protected from re-colonization and clinical disease on subsequent exposure 10 weeks later, regardless of the initial dose of L. intracellularis.  相似文献   

Breeding progress for potato chip quality in North American cultivars   总被引：1，自引：0，他引：1  

Stephen L. Love  Joseph J. Pavek  Asunta Thompson-Johns  William Bohl 《American Journal of Potato Research》1998,75(1):27-36

Forty-four potato cultivars, released in the period between 1876 and the present were grown concurrently in field trials, stored simultaneously in three different environments, then evaluated for chip quality. They represented cultivars historically used and/or bred for potato chip production. Quality factors measured were tuber solids, chip color, reducing sugar levels, sucrose levels, and percent of defect-free chips. Tuber solids tended to increase in the late period cultivars, but trends were erratic. The release of Lenape marked the beginning of an increase in tuber solids that has continued to the present. There was a significant trend for lower reducing sugars and better chip color that corresponded to increasingly later cultivar release dates. Since about 1960, progress toward lower reducing sugars and better chip color has been constant, regardless of whether tubers were stored at 4.4 C, stored at 4.4 C and reconditioned, or stored at 10 C. Late period cultivars tended to have a greater percentage of defect-free chips in comparison to those released earlier, with most of the improvement coming during the last few years. This study provided evidence that potato breeders have made significant progress in developing cultivars with good chip quality. Evidence was also found that Lenape was a landmark cultivar and has been an important contributor to the observed breeding progress  相似文献   

Infection of the subcutis and skin of cats with rapidly growing mycobacteria: a review of microbiological and clinical findings.     

R Malik  D I Wigney  D Dawson  P Martin  G B Hunt  D N Love 《Journal of Feline Medicine and Surgery》2000,2(1):35-48

Mycobacteria were isolated and characterised from 49 cats with extensive infections of the subcutis and skin. Cats were generally between 3 and 10 years of age, and female cats were markedly over-represented. All isolates were rapid-growers and identified as either Mycobacteria smegmatis (40 strains) or M fortuitum (nine strains). On the basis of Etest for minimum inhibitory concentration and/or disc diffusion susceptibility testing, all strains of M smegmatis were susceptible to trimethoprim while all strains of M fortuitum were resistant. M smegmatis strains were typically susceptible to doxycycline, gentamicin and fluoroquinolones but not clarithromycin. All M fortuitum strains were susceptible to fluoroquinolones, and often also susceptible to gentamicin, doxycycline and clarithromycin. Generally, M smegmatis strains were more susceptible to antimicrobial agents than M fortuitum strains. Treatment of mycobacterial panniculitis involves long courses of antimicrobial agents, typically of 3-6 months, chosen on the basis of in vitro susceptibility testing and often combined with extensive surgical debridement and wound reconstruction. These therapies will result in effective cure of the disease. One or a combination of doxycycline, ciprofloxacin/enrofloxacin or clarithromycin are the drugs of choice for long-term oral therapy.  相似文献   

Founding clones, major contributing ancestors, and exotic progenitors of prominent North American potato cultivars     

Stephen L. Love 《American Journal of Potato Research》1999,76(5):263-272

Neither founding clones nor major genetic contributors to modern North American potato cultivars have been systematically identified. Available pedigrees, through 12 generations, were used to identify founding clones and major contributing ancestors (MCAs), to outline relationships among these clones, to determine the genetic contribution of MCAs and exotic germplasm to prominent cultivars, and to draw conclusions about the gene base of prominent North American cultivars. Based on 1996 certified seed acreage, 46 cultivars were identified as prominent, of which 44 had published pedigrees. Using this pedigree data, 12 MCAs consisting of four types were identified: land race types including Daber and Sutton’s Flourball; immediate descendants of land race types including Busola, Early Rose, Garnet Chili, Imperator, Richter’s Jubel, and Triumph; early USDA releases including Chippewa, Earlaine, and Katahdin; and one derivative of a GermanSolanum demissum ×S. tuberosum population designated Germ. No. 3895-13. These clones appeared in the pedigrees of from 61 to 100% of the 44 most prominent North American cultivars. Some MCAs appeared numerous times in the pedigrees of the cultivars with the maximum being Busola, which appeared in the pedigree of NorDonna 94 times. Across the 44 cultivars, the genetic contribution of MCAs averaged from 1.4% for Daber to 23.2% for Katahdin. A positive genetic contribution by exotic germplasm was present in 34 of the 44 cultivars. Krantz, Russet Nugget, Conestoga, and Yukon Gold had exotic germplasm contributions of 49.5, 34.1, 32.3, and 31.3%, respectively.  相似文献   

Epidemiological studies of equine herpesvirus 1 (EHV-1) in Thoroughbred foals: a review of studies conducted in the Hunter Valley of New South Wales between 1995 and 1997.     

J R Gilkerson  J M Whalley  H E Drummer  M J Studdert  D N Love 《Veterinary microbiology》1999,68(1-2):15-25

Sero-epidemiological studies conducted between 1995 and 1997 on two large Thoroughbred stud farms in the Hunter Valley of NSW showed clear evidence of EHV-1 infection in foals as young as 30 days of age. Similarly, serological evidence suggested that these foals were infected with EHV-1 from their dams or from other lactating mares in the group, with subsequent foal to foal spread of infection prior to weaning. These studies also provided evidence of EHV-1 infection of foals at and subsequent to weaning, with foal to foal spread of EHV-1 amongst the weanlings. These data indicated that the mare and foal population was a reservoir of EHV-1, from which new cases of infection propagated through the foal population both before and after weaning. The results of these studies support the long standing management practices of separating pregnant mares from other groups of horses to reduce the incidence of EHV-1 abortion. Also, these results have important implications for currently recommended vaccination regimens, as the efficacy of vaccination in already latently infected horses is unknown.  相似文献