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151.
152.
A 14-week-old kitten had a history of vomiting, diarrhoea and pyrexia, all of which resolved without treatment. Three weeks later the kitten developed a violent non-productive dry cough. Thoracic radiographs revealed pneumothorax and nodular alveolar disease. Aelurostrongylus abstrusus larvae and intracellular Gram-negative bacilli were seen in bronchial wash fluid and pleural exudate, and Salmonella Typhimurium was cultured from both fluids but not from faeces. Therapy included unilateral closed-tube thoracostomy, enrofloxacin and fenbendazole. Historical signs were compatible with gastrointestinal salmonellosis and secondary broncho-pneumonia. Seeding of the lungs with salmonellae may have occurred as a result of migration of A abstrusus from a gastro-intestinal tract residually infected or colonised by S Typhimurium. Alternatively, the development of lungworm infection in the cat may have activated quiescent S Typhimurium pulmonary granulomata from bacteraemia secondary to gastro-intestinal salmonellosis. Two years after diagnosis the cat was reportedly in good health.  相似文献   
153.
154.
A large, bony protuberance from the frontal bone of a horse was found radiographically to communicate with the frontal sinus and to be similar in appearance. The mass was removed surgically, and the communicating defect with the sinus was repaired using synthetic mesh. Recovery was uncomplicated.  相似文献   
155.
Infectious arthritis of the tarsocrural joint was treated in 13 horses with closed suction drainage through a flat, fenestrated, latex (Jackson-Pratt) drain, broad-spectrum antimicrobial agents, nonsteroidal anti-inflammatory drugs, and bandage immobilization. In 11 horses, arthroscopic lavage and debridement were also performed. Ingress drains were placed for lavage in six horses. Ten horses returned to their previous level of competition or were sound. One horse raced but had lameness of the affected tarsocrural joint and dropped in racing class; one horse was euthanatized because of laminitis in the supporting limb; and one horse was lame, but useful as a breeding animal. Closed suction drainage appeared to be a useful treatment in horses with infectious arthritis. Although arthroscopy was not necessary, it facilitated fibrin removal, lavage, and partial synovectomy. Because of the development of Pseudomonas superinfection in one horse, the use of simultaneous ingress catheters was not recommended.  相似文献   
156.
A technique to enhance meniscal regeneration following partial meniscectomy was investigated in the dog. Twenty-four dogs underwent a partial meniscectomy (to simulate excision of a bucket handle tear in the caudal body of the medial meniscus). The excision did not communicate with the synovia. Twelve of the dogs also received a vascular access channel in which an incision was made from the free cut edge of the meniscus to the vascular synovia. The dogs were terminated at 4,8, and 16 weeks for gross, vascular, and histologic examination of the operated menisci. In all dogs, and at all time periods, the dogs receiving a vascular access channel showed increased regeneration compared to dogs undergoing partial meniscectomy alone.  相似文献   
157.
Pharmacokinetics of chloramphenicol in the neonatal horse   总被引:1,自引:0,他引:1  
Chloramphenicol sodium succinate was administered as an intravenous bolus (50 mg/kg) to eight foals which weighed 49–57 kg (mean ± 1 standard deviation = 53.19 ± 2.66) each, and were 1–9 days (4.5 ± 2.56) of age. The drug was rapidly distributed and followed first-order elimination. Mean pharmacokinetic values were: zero-time serum concentration (C0) = 36.14 μg/ml (±14.80); apparent specific volume of distribution ( Vd ) = 1.614 1/kg (±0.669); and elimination rate constant ( K ) = 0.7295 h-1 (±0.3066) which corresponds to a biological half-life ( t 1/2) = 0.95 h. These values do not differ greatly from those reported for adult horses and ponies.
A suspension of chloramphenicol was administered by nasogastric tube (50 mg/kg) to a second group of seven foals which weighed 49 to 57 kg (51.34 ± 2.82) each and were 1 to 7 days (4.43 ± 1.90) of age. A mean peak serum chloramphenicol concentration of 23.97 μg/ml (±7.06) was achieved 1.14h (±0.63) after administration. The bioavailability of this preparation was 83.27 percent.  相似文献   
158.
159.
1. Three experiments were undertaken to test the efficacy of 2 enzymes targeting mainly the non-starch polysaccharides (NSPs) in rice bran. 2. In experiment one, 400 g rice bran/kg depressed chick performance and there was a significant decline in growth rate and food intake with increasing inclusion of rice bran (0, 200, 400 g). Neither enzyme had any benefit. 3. In experiment two, rice bran (inclusion 200 and 400 g/kg), did not alter growth rate, food intake or food conversion ratio of duckling (3 to 17 d of age). Again enzyme addition gave no response. 4. In experiment three, 300 g rice bran/kg stimulated duck (19 to 35 d of age) growth while 600 g rice bran/kg depressed growth but not food intake. Enzymes gave no response. 5. Relative gut viscosity declined with increasing rice bran inclusion as did dry matter in ileal digesta. There were differences between ducklings and chickens. 6. It was concluded that NSPs were not a significant factor in altering the nutritive value of rice bran and the enzymes used were therefore unlikely to be of benefit.  相似文献   
160.
Mycoplasma spp were isolated in pure culture from bronchoalveolar lavage specimens from three cats with clinical, cytological and radiographic signs of bron-chopneumonia or suppurative bronchitis. Predisposing factors were not identified in the first case, the second cat had oesophageal hypomotility, while the third cat had been exposed to cigarette smoke and had advanced periodontal disease. Respiratory signs resolved promptly and completely in all cases following antimicrobial therapy directed against mycoplasmas. Mycoplasma spp are possible causes of lower respiratory tract disease in cats and this should be considered when selecting empirical therapy for feline airway disease and pneumonia. In some situations mycoplasmas may behave as primary lower respiratory tract pathogens in cats.  相似文献   
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