Suspected Vestia foetida poisoning in young goats     

McKeough VL  Collett MG  Parton KH 《New Zealand veterinary journal》2005,53(5):352-355

CASE HISTORY: Two crossbred, castrated male goats, a 5-month-old and an 8-month-old, were observed ingesting Vestia foetida (Solanaceae). Later, the goats were seen standing splay-legged and apparently disoriented. CLINICAL FINDINGS: When examined, both goats were in sternal recumbency and had mydriasis; the younger goat had a diminished menace response. When the goats were made to stand, they were ataxic and had muscle fasciculations of the hindquarters and face. Both had halitosis consistent with the odour of crushed Vestia leaves. The animals were treated with a mixture of vitamins and intravenous diazepam. The older goat recovered but the younger goat died and was necropsied. This animal had severe periacinar necrosis and fatty change in the liver, as well as fatty nephrosis. DIAGNOSIS: Probable Vestia foetida poisoning. CLINICAL RELEVANCE: The introduction of Vestia foetida to New Zealand and the apparent palatability of the plant necessitate that veterinarians and owners be knowledgeable about its potential toxicity. Differential diagnoses for the liver lesions (in New Zealand) would include Cestrum poisoning, acute seneciosis, acute blue-green algal poisoning, and acute and chronic copper poisoning.  相似文献   

The pathology of chronic Drechslera campanulata toxicosis in inbred rats     

M G Collett  J E Fincham  R C Tustin  G Joubert  W F Marasas 《The Onderstepoort journal of veterinary research》1988,55(1):51-57

Cultures on autoclaved maize of the phytopathogenic fungus, Drechslera campanulata, were incorporated into diets and fed to male inbred BDIX rats. In a pilot trial, a diet containing 30% D. campanulata culture material killed 5 out of 5 rats in 15-25 days. Lesions included gastric corpus erosions, gastrorrhagia and ulcerative typhlitis. Diets containing 5% or 10% culture material induced erosive to ulcerative typhlitis and oedema and hyperplasia of the ileocaecal lymph nodes in 40 out of 40 rats. Other changes included: mass loss; normocytic, hyperchromic anaemia; leukocytosis with neutrophilia; reductions in plasma proteins, creatinine, calcium and cholesterol; elevated serum enzymes; hepatosis, nephrosis and mycoplasma-like interstitial pneumonia. No lesions were present in control rats, and their profiles were normal. Ulcerative typhlitis induced by D. campanulata in rats resembles that seen in chronic piperonyl butoxide intoxication as well as that due to single treatments of indomethacid, although small intestinal ulcers are more frequent in the latter. Overgrowth of intestinal flora may be involved in ulcer pathogenesis. The pathology of drechsleratoxicosis in rats is compared to that in sheep and goats where necrotic lesions in the forestomach and, to a lesser extent, in the caecum are characteristic findings.  相似文献   

$24.50D.H. Snow and C.J. Vogel, Equine Fitness: The Care and Training of the Athletic Horse, David and Charles, Inc., Englewood Cliffs NJ (1987).     

MG 《Journal of Equine Veterinary Science》1989,9(2)

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Splenic haemangiosarcoma with metastasis to the cervical musculature in an aged pony     

Parkinson TJ  Mogg TD  Dykgraaf S  Collett MG 《New Zealand veterinary journal》2004,52(1):37-39

CASE HISTORY: An aged pony gelding presented with sudden onset of neck pain, depression and ataxia and weakness of the hindlegs, together with longer-term weight loss. Diagnostic procedures failed to isolate the cause of these signs and, despite symptomatic treatment, the animal's condition deteriorated until it required euthanasia. NECROPSY FINDINGS: Post mortem examination revealed the presence of multiple splenic and hepatic haemangiosarcomata, with metastases to the lung and dorsal cervical muscles overlying C1 and C2 vertebrae. No lesions were present in the spinal cord, spinal column or brain. CONCLUSIONS: The weight loss and neck pain were explicable in terms of the sites and extent of the tumours, although it was unclear how the severe ataxia could have been produced by such lesions.  相似文献   

Chronic sporidesmin toxicosis and photosensitisation in an alpaca (Vicugna pacos) in New Zealand     

MG Collett  AS Wehrle-Martinez  LK Whitfield  A Kokosinska 《New Zealand veterinary journal》2016,64(5):314-316

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Phthalimide‐derived strigolactone mimics as germinating agents for seeds of parasitic weeds          下载免费PDF全文

Antonio Cala  Kala Ghooray  Mónica Fernández‐Aparicio  José MG Molinillo  Juan CG Galindo  Diego Rubiales  Francisco A Macías 《Pest management science》2016,72(11):2069-2081

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Environmental factors on virulence of <Emphasis Type="Italic">Aeromonas hydrophila</Emphasis>     

Ruan E. F. Abreu  Thaís C Magalhães  Renilde C Souza  Samira TL Oliveira  Adriana MG Ibelli  Fábio N Demarqui  João JS Gouveia  Mateus M Costa  Gisele V Gouveia 《Aquaculture International》2018,26(2):495-507

Aeromonas hydrophila are known for being opportunistic pathogens, harboring various virulence factors and triggering lesions and death in fish. The disease caused by bacteria can make fish inappropriate for human consumption, besides representing a risk to public health. The pathogenesis can be influenced by environmental variables, affecting fish productivity and mortality. The present study aimed to determine whether A. hydrophila harbor the virulence genes aerolysin, hydrolipase, elastase, lipase, cytotonic enterotoxin (ast), lateral flagellum (laf), and polar flagellum (fla) and to evaluate the influence of environmental variables on in vitro growth, in vivo virulence and expression of some of these genes. Polymerase chain reaction (PCR)-based screening for the presence of these virulence genes was performed on 35 isolates. Six isolates containing different profiles of virulence genes were tested for in vitro growth under different conditions of pH, temperature, and ammonia and for in vivo virulence under these same environmental conditions. RT-qPCR was used to quantify the expression of aerolysin, lipase, and fla genes. All the tested environmental factors influenced the growth of A. hydrophila, while pH and ammonia concentrations influenced the bacterial virulence. The expression of the fla gene increased when bacteria were grown in higher ammonia concentration. The mortality established by Aeromonas is influenced by several environmental factors pinpointing the importance of its control in fish farming to avoid higher economic loses associated to bacterial disease outbreaks.  相似文献   

Influence of lipophilicity in O‐acyl and O‐alkyl derivatives of juglone and lawsone: a structure–activity relationship study in the search for natural herbicide models          下载免费PDF全文

Alexandra G Durán  Nuria Chinchilla  José MG Molinillo  Francisco A Macías 《Pest management science》2018,74(3):682-694

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Binding targets of termiticidal lectins from the bark and leaf of Myracrodruon urundeuva in the gut of Nasutitermes corniger workers          下载免费PDF全文

Thâmarah A Lima  Leonardo P Dornelles  Ana Patrícia S Oliveira  Caio CS Guedes  Sueden O Souza  Roberto A Sá  Russolina B Zingali  Thiago H Napoleão  Patrícia MG Paiva 《Pest management science》2018,74(7):1593-1599

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Growth and nutrition of Pinus radiata in response to fertilizer applied after thinning and interaction with defoliation associated with Essigella californica     

Peter Hopmans  Nick C. Collett  Ian W. Smith  Stephen R. Elms 《Forest Ecology and Management》2008

Infestations of Essigella californica following the installation of post-thinning fertilizer trials in Pinus radiata plantations provided an opportunity to examine the impact of repeated defoliation over a period of 8 years (1997–2005). Replicated treatments (n = 4) of nil fertilizer (control), N (300 kg ha⁻¹) as urea, P (80 kg ha⁻¹) and S (45 kg ha⁻¹) as superphosphates were applied immediately after thinning at three sites and this was followed by a second application of NPS fertilizers 6 years later with N applied at 300 kg ha⁻¹ as urea and ammonium sulphate and P at 80 or 120 kg ha⁻¹. Defoliation of untreated P. radiata gradually increased to 50% over a period of 8 years. Basal area growth was negatively correlated with average defoliation for two consecutive post-fertilizer periods of 6 and 2 years. Growth responses to fertilizer varied considerably between sites but the largest improvement in growth was due to NPS fertilizer, this increased basal area by 30–80%. Application of N fertilizer raised total N levels in foliage and increased defoliation with a commensurate loss in growth under conditions of deficiencies of S or P. Repeated infestations gradually increased the percentage of trees with severe defoliation (>80% loss of foliage) indicating that nutrient-deficient trees have a reduced capacity for foliage recovery between episodes of peak infestation. In contrast, treatment with N fertilizer in combination with S- and P-corrected deficiencies of these nutrients, raised levels of total N in foliage and reduced defoliation to approximately 20%. Basal area growth responses to NPS fertilizers reflected improved nutrition as well as reduced insect damage. The reduction in defoliation under conditions of balanced tree nutrition was most likely due to enhanced needle retention following correction of P deficiency as well as greater availability of nutrients enabling a more vigorous recovery of P. radiata after an episode of E. californica activity. Treatment with fertilizer therefore reduced the long-term impact of aphid damage and improved growth of P. radiata.  相似文献