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41.
Tenoscopy is the use of an arthroscope to access tendon sheaths. This article reports clinical findings, treatments, and outcomes of 33 horses with either septic or nonseptic digital tenosynovitis submitted to 36 tenoscopies during 34 occasions at the Marion duPont Scott Equine Medical Center (1997–2001). Two of the 16 horses with septic tenosynovitis were euthanized at the hospital. From the 32 horses discharged from the hospital, outcome was obtained in 31 cases: 12 horses (6 septic) could work at the same level. No difference was detected between the outcome groups regarding clinical and laboratory variables. In nonseptic cases, lameness grade, circulating white blood cells, and plasma fibrinogen before surgery were lower, while the period between the onset of clinical signs and surgery was longer and duration of phenylbutazone treatment and hospitalization was shorter. No difference in the outcome was detected when septic and nonseptic cases were compared. Tenoscopy was useful for diagnosis and treatment of nonseptic and septic digital tenosynovitis. The small number of cases and the lack of accurate information due to the retrospective nature of the study may have prevented detection of a difference between the outcomes of horses with septic versus nonseptic tenosynovitis.  相似文献   
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JOHN B. KANEENE  DVM  MPH  PhD    ULREH V. MOSTOSKY  DVM  MS    ROSEANN MILLER  MS 《Veterinary surgery : VS》2009,38(3):398-405
Objective— To determine whether there has been improvement in canine hip joint phenotype classifications of dogs whelped from 1989 to 2003 by the Orthopedic Foundation for Animals (OFA), by examining results of radiographic evaluations and identifying any trends in percentages of dogs classified as having desirable hip joint phenotypes.
Study Design— Retrospective cohort study.
Sample Population— OFA radiographic classifications (n=431,483) on dogs whelped between 1989 and 2003.
Methods— Numbers and percentages of dogs classified by hip joint phenotypes were determined for 2-year cohorts. Differences between breeds and sexes were assessed using the Fisher's exact test, and odds ratios with 95% confidence intervals were calculated to express associations. The Cochran–Armitage test for trend was calculated to identify significant trends over time.
Results— There were statistically significant ( P <.05) increases in the proportion of all breeds of dogs evaluated as excellent and good from 1993 to 2003, controlling for gender and age at evaluation. Labrador Retrievers, Bernese Mountain Dogs, and Rottweilers had the highest proportions of excellent and good scores, and the highest rates of improvement in excellent and good scores were seen in Bernese Mountain Dogs and Rottweilers.
Conclusions— Results support the contention that there have been improvements in hip joint phenotype classifications in dogs in the United States since the previous study (1989–1992), through increases in the proportion of dogs receiving excellent and good classifications.
Clinical Relevance— Hip joint phenotype classifications can be used by dog breeders to develop breeding programs to improve the hip joints of future generations of dogs.  相似文献   
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The feasibility and reproducibility of obtaining the pulsed-wave Doppler measurements of resistive index (RI) and pulsatility index (PI) were investigated in intrarenal arteries of normal, nonsedated cats, and cats anesthetized with isoflurane. In addition, relative renal function and relative renal blood flow were evaluated using quantitative renal scintigraphy. The percentage of injected dose uptake, time to peak activity, and two indices of renal blood flow (K/A ratio and flow index) obtained during the first pass of 99mTc-MAG3, were determined for both awake and anesthetized cats. Results indicate that measuring RI and PI in nonsedated cats is readily accomplished and that the results are reproducible within an animal. Mean RI and PI values in the awake cats were 0.55 and 0.8, respectively. Significant differences between the awake and anesthetized cats were found for all pulsed-wave Doppler and quantitative renal scintigraphic measurements evaluated.  相似文献   
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A relative immunodeficiency of young foals is considered to account for the increased susceptibility of foals to infectious diseases, including pneumonia caused by Rhodococcus equi. In this report, peripheral blood mononuclear cells (PBMCs) from healthy foals at 14 and 56 days of age, or from their dams, were incubated with three stimulatory and one nonstimulatory (control) synthetic cytosine-phosphate-guanosine oligodeoxynucleotides (CpG-ODNs), and mRNA expression of tumor necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), interleukin (IL) -6, IL-8, IL12-p35, and IL-12p40 were determined. Results indicated that synthetic CpG-ODNs can induce strong, rapid cytokine responses in healthy foals and adult horses. B-class CpG-ODNs 2135 and 2142 induced greater messenger RNA (mRNA) expression of IFN-γ, IL-6, and IL-12p40 than the C-class CpG-ODN 2395 in foal PBMCs. In foals, B-class CpG-ODNs induced IFN-γ, IL-6, and IL-12P40 mRNA expression that was similar to or higher in magnitude than that observed in adult horses. These observations indicate that CpG-ODNs might be useful as immunomodulators or as potential adjuvants for vaccines to aid in preventing R. equi pneumonia and other bacterial diseases of foals.  相似文献   
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The records of 361 Standardbred mares and their 1986 or 1987 foals were evaluated to identify factors associated with failure of passive transfer (FPT) of colostral antibodies in equine neonates. Sixty-five foals (18%) were classified as FPT based on a serum immunoglobulin concentration of less than 400 mg/dl at 24 to 36 hours of age, determined by the glutaraldehyde coagulation test. The potential association of mare- and foal-related factors with FPT were assessed by reviewing a series of multiple logistic regression models. The season in which the mare foaled and foal exam score, a subjective assessment of foal vigor, maturity, and general health, were the primary factors associated with the development of FPT. Foals with FPT were more likely (odds ratio = 3.50; 95% confidence interval = 1.81-6.68) than normal foals to require medical therapy during the first 3 months after parturition.  相似文献   
49.
近15年来,我亲自参与了3次禽流感流行时的处理工作。其中第一次是由高致病性H5N2禽流感病毒所引起,第二次由低致病性H5N2禽流感病毒、第三次由无致病性H7N2禽流感病毒所引起。虽然我们对每次流行的处理方法略有不同,但都达到了从商业鸡群和家禽业中扑灭这些病毒的目的。我们除了有处理这3次禽流感的经验,还在近12年来实行了一个全州范围的禽流感监测计划。按此计划,我们每年取14万份以上的血样和蛋样作禽流感病毒抗体检测。如果血样和蛋中存在这种抗体,即说明其接触过禽流感病毒,所以这是一种有效方法来确认我们的鸡群中是否存在尚未发现…  相似文献   
50.
Determination of urolith mineral composition is critical for management of urolithiasis in dogs and cats. Using computed tomography, urolith physical density, and hence chemical composition, can be quantified using mean beam attenuation measurements (Hounsfield units; HU). This study was designed to establish in vitro reference ranges for three types of compositionally pure uroliths retrieved from dogs. Sixty-six canine uroliths (22 uric acid, 21 calcium oxalate, 14 struvite, nine mixed or compound) were placed in a phantom array. Uroliths were scanned at 120 kVp, 200 mA, and 80 kVp, 200 mA. The region of interest (ROI) for mean HU calculation was determined using two techniques, and reference ranges were calculated for each kVp using either ROI technique. HU for urolith types of pure composition were statistically different (Wilcoxon's two-sample test, P < 0.0083 [Bonferonni correction with six comparisons for total P < 0.05]) using both ROI techniques at either kVp. Struvite uroliths were not statistically different from mixed or compound uroliths. The accuracy for determination of composition of pure uroliths ranged from 86% to 93%; the prediction accuracy for each urolith mineral type and for all uroliths in general was highest when the ROI was hand-drawn just within the visible urolith border at 80 kVp. Technique of ROI determination and kVp that yielded the highest sensitivity, specificity, and positive and negative predictive values varied for each urolith type. Therefore, in this study, HU could be used to differentiate three types of uroliths of pure mineral composition in vitro. Further studies are needed to determine the predictive value of HU in vivo.  相似文献   
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