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Equine Post-anesthetic Lameness A Retrospective Study 总被引:1,自引:0,他引:1
MEGHAN T. RICHEY DVM MELISSA S. HOLLAND DVM DiplomateACVA CHARLES J. McGRATH DVM DiplomateACVA NICHOLAS H. DODMAN BVMS MRCVS DVA DipomateACVA DURWOOD B. MARSHALL ESS MICHAEL H. COURT BVSc DiplomateACVA WENDY M. NORMAN BVSc DAVID C. SEELER DVM MSC DiplomateACVA 《Veterinary surgery : VS》1990,19(5):392-397
The incidence of post-anesthetic lameness in 655 horses undergoing 733 anesthetic episodes over a 3 year period was 6.4%. Nineteen factors previously reported or proposed to play a role in the development of post-anesthetic lameness were evaluated statistically. Only hypotension and the duration of the anesthetic period were significant factors. 相似文献
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Recombinant Bone Morphogenetic Proteins: Novel Substances for Enhancing Bone Healing 总被引:1,自引:0,他引:1
CARL A. KIRKER-HEAD MA Vel MB MRCVS Diplomate ACVS Diplomate ECVS 《Veterinary surgery : VS》1995,24(5):408-419
Bone morphogenetic proteins (BMPs) are differentiative factors whose principal function is to induce transformation of undifferentiated mesenchymal cells into chondroblasts and osteoblasts in a dose-dependent manner. Bone morphogenetic proteins have been isolated postnatally in mammals from bone matrix, periosteal cells, mesenchymal cells of marrow stroma, tooth anlagen, and cells of osteosarcoma and chondrosarcoma. Distribution in additional embryonic tissues implies a broader organogenic function. Bone morphogenetic proteins are the only differentiative factors able to singularly induce de novo bone formation in vitro and in vivo. Recombinant DNA technology allows their production in large and highly purified quantities. The BMPs' osteoinductive ability has been shown with a variety of carriers including collagens and polymers at heterotopic and orthotopic sites in a wide range of species. They are presently being readied for clinical use as alternatives to bone grafts. Other potential applications include use as pulp capping agents, promoters of implant osteointegration and soft tissue reunion with bone, treatments for nonadaptive bone disease, and implants for use with mitotically expanded skeletal stem cell populations. Errors in the genetic coding of BMPs may manifest as clinical disease entities. 相似文献
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Dez Hughes BVSc MRCVS R. E. Moreau DVM K. L. Overall VMD T. J. Van Winkle VMD 《Journal of Veterinary Emergency and Critical Care》1996,6(1):13-20
A retrospective analysis was conducted of all feline necropsies performed during a nine year period to identify cases of sever, acute, centrilobular (periacinar), hepatic necrosis (ACHN). After exclusion of cats with anemia, a series of seven cases of ACHN was identified. In addition, two similar cases were identified from tissue submitted for histopathology following, and eight had bile duct hyperplasia. Seven of the nine cats received diazepam prior to dath, and one received zolazepam. Of the seven cats that received diazepam, five were healthy prior to treatment and received oral diazepam for the treatment of inappropriate urination, intercat aggression, or skin disease. Two cats which received diazepam exhibited other clinical signs: one had chronic vomiting, and the other received diazepam after biochemical evidence of hepatocellular necrosis was present. Onset of clinical sings in cats receiving oral diazepam occurred 7–13 days following the initiation of treatment. Clinical signs and clinical biochemical analysis were compatible with severe hepatocellular necrosis and acute liver failure. All cats had lesions in other organs: five had pancreatic disease, five had cardiac disease, and five had renal disease. All cats died, or were euthanized, within 4 dyas of the onset of clinical signs and 2 days after presentation to a veterinarian. Fatal, acute, centrilobular hepatic necrosis appears to be a serious adverse reaction to diazepam therapy in certain cats. 相似文献
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DAVID A. WILSON DVM MS Diplomate ACVS GORDON J. BAKER BVSc PhD MRCVS Diplomate ACVS MICHAEL J. BOERO DVM MS Diplomate ACVS 《Veterinary surgery : VS》1995,24(6):506-514
Complications of celiotomy incisions were evaluated retrospectively in 274 horses that survived at least 1 month after surgery, or died or were euthanatized within 1 month of surgery, as a direct result of these complications. Horses were divided into four groups; group A, a ventral median celiotomy for intestinal disease; group B, ventral median celiotomy for nonintestinal disease; group C, repair of an umbilical hernia; and group D, celiotomy in a region other than the midline. Specific incisional complications were peri-incisional edema, drainage, incisional abscess, suture sinus, and dehiscence. Incision-related complications occurred in 30% of the horses (group A, 40%; group B 18%; group C, 7%; and group D, 88%). Complications occurred more frequently in group D than group A ( P =.009), which were higher than in groups B and C ( P <.00001). Incisional hernia occurred in 28 of 256 (11%) horses that survived at least 4 months and were available for follow-up. Hernia formation was more common ( P <.00001) in horses that had other incisional complications (23 horses) than those without (5 horses). Serous or purulent incisional drainage, were more likely to be associated with hernia formation than was serosanguineous drainage or other incisional complications. 相似文献
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Phillip F. Steyn BVSc MRCVS MS David Twedt DVM Wanda Toombs CVT 《Veterinary radiology & ultrasound》1995,36(4):327-331
The gastric emptying half-time of solid food in normal cats was determined using a scintigraphic technique. 99m Tc-sulfur colloid was applied to dry food. Sequential images were acquired post prandial, and the gastric emptying half-time was determined for several different acquisition and processing parameters. Good correlation was found between different acquisition and processing methods, some of which made use of edge detection applications, while others used different views, or number of views from which the gastric emptying half-time was calculated. The mean ± standard deviation, (range) and median of the gastric emptying half-time determined using the geometric mean of total counts in hand-drawn regions of interest from the lateral and ventral images were 2.47 × 0.71, (1.42–3.61) and 2.37 hours respectably. 相似文献