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A double crossover trial, consisting of two three-week periods, was conducted to evaluate an air ionizer unit and its effects on cellular respiratory defenses in racing Thoroughbreds. Each week, samples of the stable air were taken and horses were sampled for hematological and blood biochemical analyses. At the end of both three-week periods, blood neutrophil and bronchopulmonary lavage immune cellular responses were assayed and bronchopulmonary lavage samples were cultured aerobically and anaerobically. The air ionizer unit had no significant effects on the parameters assayed.  相似文献   
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In summary, therefore, my experiences as a witness have been divided into three major areas. In the first, in what was essentially the political process, the game was charge and counter-charge, and the rules, such as they were, were fairly loose. In the second area, that of administrative hearings, the rulesare somewhat tighter, but still not as restrictive as those of a full court session. In court session you are always sworn, carefully qualified as an expert and almost invariably subjected to searching cross- examination. The rules of evidence are strictly adhered to. This is the situation where your freedom of action is most restricted, and is the most rigorous of the situations in which you will use your expertise. However, in the last analysis, you should remember that all that is required of you are simple statements of fact,and your best opinions. Make your statements simple, consistent, and concise, and keep your answers on cross-examination as short as possible.Expert appearances under any of these conditions are very stressful circumstances. They will absorb your attention entirely for some time before you make your appearance. You will feel totally drained after them,and images from the hearing will reverberate in your mind for days. They are, nevertheless, ultimately satisfying experiences. This is because the only measure of the quality of your research is how much it changes the way things are done. Appearances as an expert are a sure sign that you are contributing to change, and speak the significance of your expertise.  相似文献   
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Objective— To evaluate the use of sinoscopy for detection and treatment of ventral conchal sinus (VCS) and/or rostral maxillary sinus (RMS) disease in horses.
Study Design— Case series
Animals— Horses (n=60) with suspected paranasal sinus disease.
Methods— Horses were evaluated by sinoscopy through a conchofrontal sinus (CFS) portal with ventral conchal bulla (VCB) fenestration. Other endoscopic sinus approaches and adjunctive diagnostic tests; oral examination, computed tomography, radiography, scintigraphy and endoscopic examination of the upper portion of the respiratory tract were used in some horses.
Results— The CFS approach permitted adequate observation of the RMS and VCS in 53 horses (88%). Hemorrhage caused by VCB fenestration prevented examination of the RMS and/or VCS in 12 horses (21%). Observation of lesions was possible in all horses diagnosed with neoplasia, sinus cysts, and progressive ethmoidal hematomas. Endoscopy of the paranasal sinuses was useful diagnostically in 82% of horses with primary sinusitis. Other diagnostic modalities were usually required to confirm a diagnosis of dental sinusitis.
Conclusions— Trephination into the CFS with VCB fenestration is a minimally invasive technique that provides consistent access to the RMS and VCS. It facilitates diagnosis of many sinus disorders and endoscopically guided treatment of many horses with sinus cysts and primary sinusitis, in combination with sinus lavage.
Clinical Relevance— Many diseases affecting the RMS and VCS can be diagnosed and resolved endoscopically using a CFS approach with VCB fenestration, thus avoiding the need for osteoplastic sinus surgery and its associated risks and complications.  相似文献   
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A 12-year-old, neutered male, domestic long-hair cat was evaluated for a 6-month history of inspiratory stertor and epiphora. In computed tomography of the skull and pelvis, and radiographs of the thorax, right femur and stifle there was generalized osteosclerosis, with obliteration of the nasal turbinates and nasolacrimal duct obstruction. The cat also had a large fibrosarcoma involving the right pelvic limb. Osteosclerosis is a rare disorder that is poorly understood but has been described in several species. Various manifestations, potential causes, and radiologic findings of osteosclerosis are discussed.  相似文献   
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