Effects of pimobendan on myocardial perfusion and pulmonary transit time in dogs with myxomatous mitral valve disease: a pilot study          下载免费PDF全文

SM Apple  G Menciotti  L Braz‐Ruivo  S Crosara  J Häggström  M Borgarelli 《Australian veterinary journal》2016,94(9):324-328

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Factors influencing the reproduction and production performance of the Nguni cattle ecotypes in South Africa     

Sónia Maria Ataíde Maciel  Michael Denis Fair  Michiel Matthys Scholtz  Frederick Wilhelm Cornelius Neser 《Tropical animal health and production》2016,48(1):75-85

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Early luteal development in Santa Inês ewes superovulated with reduced doses of porcine follicle‐stimulating hormone     

Mariana Garcia Kako Rodriguez  Giovanna Serpa Maciel  Ricardo Andres Ramirez Uscategui  Victor Jos Correia Santos  Ricardo Perecin Nociti  Priscila Del Aguila da Silva  Marcus Antnio Rossi Feliciano  Felipe Zandonadi Brando  Jeferson Ferreira Fonseca  Maria Emilia Franco Oliveira 《Reproduction in domestic animals》2019,54(3):456-463

The aim was to compare the early luteal development in ewes superovulated with different doses of pFSH. Twenty‐nine Santa Inês ewes received a progesterone device (CIDR®) for 8 days. Gonadotrophic treatment started on Day 6: G200 (control, n = 9, 200 mg); G133 (n = 10, 133 mg); and G100 (n = 10, 100 mg of pFSH). On Day 6, all females received eCG (300 IU). B‐mode and spectral Doppler ultrasonography were performed daily during the early luteal phase (Days 11–15) to monitor the development of corpora lutea (CLs; dimensions) and ovarian arteries indices. CLs were also classified as normal or prematurely regressed (PRCL) on Day 15 by videolaparoscopy. Ewes from G100 and G133 showed gradual increase in luteal diameter during the early luteal phase (p < 0.001), whereas G200 animals presented increase from Day 11 to Day 13, and then decrease on Days 14 and 15 (p < 0.001). The G200 females showed greater percentage of PRCL (45.20%) than those of the other groups (p < 0.001). The normal CLs number was greater in G100 than in G133 (p = 0.04), while the PRCL number was greater in G200 than in the other groups (p = 0.03). Resistive index (RI) was greater in G200 than in G100 (p = 0.02). RI was lower in Day 12 than Day 15 (p = 0.02). Pulsatility index (PI) was greater on Days 14 and 15 (p < 0.01). In conclusion, the lowest dose of pFSH (100 mg) can be considered sufficient for an efficient superovulatory response in sheep, producing better CLs development dynamic in early luteal phase and ovarian blood perfusion and smaller number of PRCL than the traditional (200 mg) pFSH dose.  相似文献   

Low occurrence of pathogenic Yersinia enterocolitica in pig tonsils at slaughter in Southern Brazil     

Wildemann  Paula  Gava  Danielle  Sfaciotte  Ricardo Antônio Pilegi  Melo  Fernanda Danielle  Ferraz  Sandra Maria  da Costa  Ubirajara Maciel  Vaz  Eliana Knackfuss 《Tropical animal health and production》2018,50(3):671-675

Tropical Animal Health and Production - Yersinia enterocolitica is a foodborne pathogen and pigs are the main reservoir of it in their tonsils. As Brazil is a large producer and exporter of pork...  相似文献   

Sperm motility of Rhamdia quelen studied using computer-assisted analysis by open-source software     

Eduardo Antônio Sanches  Robie Allan Bombardelli  Ronan Maciel Marcos  Giovano Neumann  César Pereira Rebechi De Toledo  Elizabeth Romagosa 《Aquaculture Research》2010,42(1):153-156

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Ovicidal and larvicidal activity of Melia azedarach extracts on Haemonchus contortus   总被引：1，自引：0，他引：1  

Maciel MV  Morais SM  Bevilaqua CM  Camurça-Vasconcelos AL  Costa CT  Castro CM 《Veterinary parasitology》2006,140(1-2):98-104

Haemonchus contortus is responsible for severe economic losses in sheep and goat breeding in the Northeast of Brazil. However, the effectiveness of control is compromised due to anthelmintic resistance and misuse. In the search for natural anthelmintics, Melia azedarach L., a plant indigenous to India but now distributed throughout Brazil, was selected due to the reported anthelmintic properties of its seeds. The aim of this study was to evaluate the anthelmintic activity of the seed and leaf extracts of the Brazilian adapted plant and investigate the type of organic chemical compounds present in the most active extracts. The ovicidal and larvicidal activity of M. azedarach extracts on H. contortus was evaluated through egg hatching and larval development tests. Hexane and ethanol extracts of seeds and chloroform and ethanol extracts of leaves of M. azedarach were used in the tests. To perform the larval development test, feces of an animal free from parasites were mixed with third instar H. contortus larvae and extracts in several concentrations. The coprocultures were incubated for 7 days at 30 degrees C, then the larvae were recovered and counted. LC50 was calculated by probits using the SPSS 8.0 program. The seed ethanol extract was the most active on eggs (LC50=0.36mgmL(-1)) and the leaf ethanol extract showed the best inhibition of larval development (LC50=9.18mgmL(-1)). Phytochemical analysis of the most active extracts revealed the presence of condensed tannins, triterpenes and alkaloids.  相似文献   

Anthelmintic activity of Azadirachta indica A. Juss against sheep gastrointestinal nematodes     

Costa CT  Bevilaqua CM  Maciel MV  Camurça-Vasconcelos AL  Morais SM  Monteiro MV  Farias VM  da Silva MV  Souza MM 《Veterinary parasitology》2006,137(3-4):306-310

Gastrointestinal nematode control has been performed through use of anthelmintics. However, the development of resistant populations has required research into new alternatives. There are popular reports about anti-parasitic activity of Azadirachta indica in animals and plants. The aim of this study was to evaluate the anthelmintic activity of A. indica after feeding sheep with the dried leaves. In this experiment, 40 sheep were allotted into four treatment groups. Group I received a treatment of A. indica dry leaves mixed in a concentrate at a rate of 0.1 g/kg dose for 3 months. Group II was treated with double the dose of Group I. Group III was treated with closantel (Diantel) at the manufacturer-recommended dose once at the beginning of the study and Group IV was not treated. To compare treatment effects, the following parameters were evaluated: egg count per gram of feces (EPG), worm burden, weight gain and haematocrit. EPG and worm burden results were statistically evaluated using the Kruskal-Wallis test. Haematocrit and live weight gain were submitted to analysis of variance (ANOVA) and the means evaluated by Tukey's test with 95% probability. None of the evaluated parameters of the treatment groups were statistically different when compared to the control group, demonstrating that, with the protocol used, A. indica has no anthelmintic effect.  相似文献   

Comparison of Analgesic Effects of Caudal Epidural 0.25% Bupivacaine with Bupivacaine Plus Morphine or Bupivacaine Plus Ketamine for Analgesia in Conscious Horses     

Rafael DeRossi  Tiago J.C. MódoloRonaldo C. Pagliosa  DVM  Paulo H.A. JardimFelipe B. Maciel  DVM  Gustavo G. Macedo  DVM  MSc  Dr 《Journal of Equine Veterinary Science》2012

The aim of this study was to compare the effects of caudal epidural bupivacaine alone (BP), bupivacaine plus morphine (BPMP), and bupivacaine plus ketamine (BPKE) for perineal analgesia in horses. Each of the six saddle horses received a caudal epidural catheter and underwent 3 treatments: BP, 0.25% (0.04 mg/kg) bupivacaine hydrochloride without epinephrine; BPMP, 0.02 mg/kg of bupivacaine combined with 0.1 mg/kg of morphine-preservative free; and BPKE, 0.02 mg/kg of bupivacaine combined with 0.5 mg/kg of ketamine. The order of treatments was randomized. The cardiovascular system, respiratory rate, quality of analgesia, sedation, and motor blockade were assessed before drug administration (baseline), at 5, 10, 15, and 30 minutes, and every 30 minutes thereafter until loss of analgesia. The median time to onset of analgesia was 5 minutes after BP treatment, faster than after BPKE or BPMP treatments, which were 10 minutes and 15 minutes, respectively (P < .05). The BPMP treatment produced analgesia (315 minutes) for a longer duration than BP treatment (210 minutes) or BPKE treatment (240 minutes), in the regions of the tail, perineum, and upper hind limb in horses. All treatments presented mild sedation or motor blockade. There were minimal effects on the cardiovascular system and respiratory rate. BPMP may be preferable to a high dose of BP or BPKE. Caudal epidural BPMP can be an appropriate choice for regional perineal analgesia in horses.  相似文献   

Third‐compartment cannulation in alpacas using a polyurethane gastrostomy tube     

GW Smith  MP Gerard  NB Campbell  DM Foster  SM Smith  JL Davis 《Australian veterinary journal》2009,87(12):487-491

Objective To develop a simple and effective surgical technique for third‐compartment cannulation in alpacas. Design Prospective study using six adult male alpacas. Methods General anaesthesia was induced and a polyurethane gastrostomy tube was surgically implanted into the distal portion of the third compartment. Results Three of the alpacas retained their cannulas for a 100‐day period; however, three cannulas were dislodged during the study. Two of the three dislodged cannulas were replaced during a second surgical procedure. Cannulas were well tolerated by the alpacas and all animals remained clinically healthy during the study period. Third compartment contents did not leak from the cannulation site. The tubes were manually removed following the completion of the study and the small defect in the body wall quickly healed over in all animals. Conclusion Surgical placement of polyurethane tubes designed for percutaneous endoscopic gastrostomy is a useful method of cannulating the third compartment in camelids. This technique can be used for experimental studies and possibly could be used for nutritional support and fluid therapy in sick camelids that might need long‐term care.  相似文献   

Molecular mechanism of Chinese medicine formula (Bushen Bugu Tang) for the treatment of postmenopausal osteoporosis     

TENG Xiao-ying  WANG Lian-tang  Huang L  Kumta SM 《园艺学报》2004,20(11):2005-2010

AIM: To study the molecular mechanism of Chinese medicine formula Bushen Bugu Tang (BSBGT) for the treatment of postmenopausal osteoporosis (PMO). METHODS: Forty female SD rats were divided into four groups: the sham group, OVX group, estrogen treatment group and BSBGT treatment group, ten for each, difference operation and treatment were given. Subsequently, bone mineral density (BMD), bone histomorphometric changes and collagen type I expression in the femur of these rats were examined. In order to position the target of the formula acting on bone, the effect of BSBGT on regulation of mRNA levels of RANKL and OPG, two key factors for regulating osteoclastogenesis, by using rat calvarial-derived stromal cell cultrues, was elucidated. RESULTS: The BSBGT formula was found as effective as estrogen in preventing the reduction of BMD, the trabecular area and trabecular numbers in femora and also the decrease in collagen type I expression following ovariectomy. RT-PCR resulted showed that both estrogen and BSBGT significantly up-regulated OPG mRNA level and down-regulated RANKL mRNA level, resulting in an increased ratio of OPG/RANKL in cultured rat stromal cells. CONCLUSIONS: The ratio of OPG/RANKL within the osseous environment determines whether bone formation predominates bone resorption. We therefore concluded that the BSBGT formula might be as effective as estrogen in prevention of postmenopausal osteoporosis through the mechanism of up-regulating RANKL expression and down-regulating OPG expression in osteoblast/stromal cells.  相似文献