Comparison of two species‐specific oscillometric blood pressure monitors with direct blood pressure measurement in anesthetized cats          下载免费PDF全文

Sofia A. Cerejo Med Vet  MSc  Francisco J. Teixeira‐Neto Med Vet  MSc  PhD  Natache A. Garofalo Med Vet  MSc  PhD  Jéssica C. Rodrigues Med Vet  MSc  Nathalia Celeita‐Rodríguez Med Vet  MSc  Angie P. Lagos‐Carvajal Med Vet  MSc 《Journal of Veterinary Emergency and Critical Care》2017,27(4):409-418

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Use of cryopoor plasma for albumin replacement and continuous antimicrobial infusion for treatment of septic peritonitis in a dog          下载免费PDF全文

Meaghan K. Ropski DVM  Julien Guillaumin DVM  DACVECC  DECVECC  Andrea A. Monnig DVM  DACVECC  Katy Townsend DVM  MSc  DACVS  Mary A. McLoughlin DVM  MSc  DACVS 《Journal of Veterinary Emergency and Critical Care》2017,27(3):348-356

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Surgical retrieval of a guide wire lost during central venous catheterization in a dog          下载免费PDF全文

Jade M. Hardy MS  DVM  Jennifer L. Lansdowne DVM  MSc  DACVS  DECVS  Carol A. Himsel DVM  Sean R. Freer DVM  DACVR 《Journal of Veterinary Emergency and Critical Care》2017,27(3):342-347

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Acute encephalopathy in a 2‐year‐old pot‐bellied pig following accidental intoxication with clonazepam          下载免费PDF全文

Emilie L. Setlakwe DVM  MSc  DACVIM  Amy L. Johnson DVM  DACVIM 《Journal of Veterinary Emergency and Critical Care》2017,27(3):369-372

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Epidermolysis bullosa simplex in sibling Eurasier dogs is caused by a PLEC non‐sense variant          下载免费PDF全文

Elizabeth A. Mauldin  Ping Wang  Thierry Olivry  Paula S. Henthorn  Margret L. Casal 《Veterinary dermatology》2017,28(1):10-e3

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Investigating the impact of innate dexterity skills and visuospatial aptitude on the performance of baseline laparoscopic skills in veterinary students          下载免费PDF全文

Mathew R. A. MacCormick  Jessica J. Kilkenny MSc  Meagan Walker BSc  Alex zur Linden DVM  DACVR  Ameet Singh DVM  DVSc  DACVS 《Veterinary surgery : VS》2017,46(8):1175-1186

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Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development,progression and evaluation of three immunomodulatory drugs (ciclosporin,hydroxychloroquine, and adalimumab) in a controlled environment     

Elizabeth A. Mauldin  Daniel O. Morris  Dorothy C. Brown  Margret L. Casal 《Veterinary dermatology》2010,21(4):373-382

Six German shorthaired pointer dogs (two females, four males) with exfoliative cutaneous lupus erythematosus (ECLE) were studied in a controlled setting until disease progression necessitated euthanasia. During investigations into the heredity of disease, five dogs received immunomodulatory drugs to alleviate clinical signs (lameness, erythema, scaling, erosions/ulcers). One dog served as a control and received only baths and oral fatty acids. Four dogs received ciclosporin (5–10 mg/kg once daily) for 4.5 months to 2 years. Ciclosporin decreased erythema and arthralgia, but did not halt worsening of lesions. Three dogs received hydroxychloroquine (5–10 mg/kg once daily) for 8 weeks, 7 months, and 9 months, respectively, with no side effects. Hydroxychloroquine appeared to slow clinical progression in two dogs on extended treatment and normalized globulin levels in all three dogs while receiving the drug. Four dogs, including the control dog, were euthanized between 1 and 4.5 years of age. Two remaining male dogs received a tumour necrosis factor (TNF)‐α antagonist, adalimumab, at 0.5 mg/kg every 2 weeks for 8 weeks then weekly for 8 weeks. Serum TNF‐α levels were not significantly altered nor were quantifiable changes seen in skin lesions or lameness. Subsequently, the dogs were maintained on hydroxychloroquine for another year. This is the first study to evaluate the use of a TNF‐α inhibitor for canine lupus and the first to address the safety of long‐term administration of hydroxychloroquine, albeit in a small number of dogs. The study documents the progression of ECLE and generally poor response to therapy.  相似文献   

Influence of Changes in Body Weight on Peak Vertical Force in Osteoarthritic Dogs: A Possible Bias in Study Outcome     

MAXIM MOREAU  MSc    ÉRIC TRONCY  DV  PhD    SYLVAIN BICHOT  MSc    BERTRAND LUSSIER  DMV  MSc  Diplomate ACVS 《Veterinary surgery : VS》2010,39(1):43-47

Objective— Force platform gait analysis is a recognized clinical evaluation tool that captures and documents the in vivo pathomechanics of osteoarthritis (OA). In a clinical trial designed to evaluate the impact of 2 specific diets, an increase in body weight (BW) was observed in lame client-owned dogs. Covariance analysis was used to evaluate the interference of BW changes toward the evolution of peak vertical force (PVF) values. These secondary findings are reported in this study.
Study Design— Prospective study.
Animals— Lame dogs (n=26).
Methods— Dogs with radiographic evidence of OA and low PVF values were fed with 2 specific diets for 30 and 60 days. PVF and BW were recorded at baseline, day 30 (D30), and D90.
Results— Mean (±SD) PVF values (%BW) did not differ significantly over time (D0: 63.9±17.2; D30: 65.5±17.4; and D90: 66.5±20.1). In contrast, BW (kg) was significantly higher at D90 (41.3±7.9) when compared with D30 (39.9±8.4) and D0 (40.0±8.7). Upon covariance analyses, BW changes interfere significantly with PVF values already normalized in %BW ( P =.013). Values of PVF adjusted using BW as a covariate were then 63.4±17.1 (D0), 65.0±17.3 (D30), and 67.6±20.5 (D90), whereas D90 was significantly higher than D0.
Conclusion— These findings highlighted the interference of changes in BW toward locomotor function of OA dogs when using PVF values normalized in %BW. Exacerbation of lameness when a gain in BW occurred was also sustained, raising a possible bias in clinical study outcomes.
Clinical Relevance— A BW increase in dogs with OA could exacerbate a preexisting lameness and induce a bias in clinical trials.  相似文献   

Management of Tibial Fractures Using a Circular External Fixator in Two Calves     

Hari Prasad Aithal MVSc  PhD  Prakash Kinjavdekar MVSc  PhD  Abhijit Motiram Pawde MVSc  PhD  Gaj Raj Singh MVSc  PhD  Harish Chandra Setia MSc 《Veterinary surgery : VS》2010,39(5):621-626

Objectives: To report the repair of tibial diaphyseal fractures in 2 calves using a circular external skeletal fixator (CEF). Study Design: Clinical report. Animals: Crossbred calves (n=2; age: 6 months; weight: 55 and 60 kg). Methods: Mid‐diaphyseal tibial fractures were repaired by the use of a 4‐ring CEF (made of aluminum rings with 2 mm K‐wires) alone in 1 calf and in combination with hemicerclage wiring in 1 calf. Results: Both calves had good weight bearing with moderate lameness postoperatively. Fracture healing occurred by day 60 in 1 calf and by day 30 in calf 2. The CEF was well maintained and tolerated by both calves through fracture healing. Joint mobility and limb usage improved gradually after CEF removal. Conclusions: CEF provided a stable fixation of tibial fractures and healing within 60 days and functional recovery within 90 days. Clinical Relevance: CEF can be safely and successfully used for the management of selected tibial fractures in calves.  相似文献   

The Influence of a Particle Separation Technology on the Generation of Airborne Particles from Different Roughages and Bedding Materials Used for Horses     

Felix Garlipp  MSc  Engel F. Hessel  Matthieu van den HurkMark F. Timmerman  Dr.  Herman F.A. Van den Weghe 《Journal of Equine Veterinary Science》2010

Four different types of bedding materials (wheat straw, wood shavings, hemp shives, flax shives) and two roughages (hay, haylage) were treated using an air-driven particle separation technology. The airborne particle and mold generation of both treated and untreated samples were then analyzed under standardized laboratory conditions. In addition, samples of all the treated materials were stored for 8 weeks either in a pressed or incoherent form and then analyzed again for their ability to generate airborne particles. The airborne particle concentrations were detected online with the gravimetrically measuring analyzer tapered element oscillating microbalance (TEOM) 1400a that was equipped successively with different inlets to measure the particle fractions PM₂₀, PM₁₀, PM_2.5, and PM_1.0 (PM = Particulate matter). The particle separation resulted in a reduction in the airborne particle (PM₂₀) generation in all materials: hay 49.16 to 22.79 mg/m³ (53.6%), haylage 28.57 to 25.04 mg/m³ (12.3%), wood shavings 141.68 to 15.04 mg/m³ (89.4%), wheat straw 143.08 to 22.97 mg/m³ (83.9%), flax 135.11 to 53.31 mg/m³ (60.5%), and hemp 63.67 to 17.64 mg/m³ (72.3%). The 8-week storage of the treated materials as compressed materials led to a renewed significant increase in the airborne particle (PM₁₀) concentration in the haylage (+29.9%), wheat straw (+104.0%), wood shavings (+40.4%), and hemp shives (+30.7%). Storage of the incoherent materials caused a significant increase in these particles only in the wheat straw (+44.2%). The separation treatment reduced the mold production by 92.4% in the wood shavings, 88.0% in the wheat straw, and 85.8% in the hay.  相似文献