Agreement between two oscillometric blood pressure technologies and invasively measured arterial pressure in the dog          下载免费PDF全文

Anderson F da Cunha  Hugues Beaufrère  Amanda Shelby  Rhett Stout  Mark J Acierno 《Veterinary anaesthesia and analgesia》2016,43(2):199-203

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Perioperative trends in plasma colloid osmotic pressure in horses undergoing surgery          下载免费PDF全文

Alexandra G. Raftery MA  VetMB  Ruth A. Morgan MA  VetMB  DECEIM  Paul D. MacFarlane BVSc  DECVAA 《Journal of Veterinary Emergency and Critical Care》2016,26(1):93-100

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Hyperlactatemia and serial lactate measurements in sick cats          下载免费PDF全文

Lesleigh A. Redavid DVM  DACVECC  Claire R. Sharp BSc  BVMS  MS  DACVECC  Mark A. Mitchell DVM  MS  PhD  DECZM  Nicole F. Beckel DVM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2016,26(4):495-501

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Effect of Regional Intravenous Limb Perfusate Volume on Synovial Fluid Concentration of Amikacin and Local Venous Blood Pressure in the Horse          下载免费PDF全文

Darla K. Moser  Mike J. Schoonover  Todd C. Holbrook  Mark E. Payton 《Veterinary surgery : VS》2016,45(7):851-858

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Dual Bone Fixation: A Biomechanical Comparison of 3 Implant Constructs in a Mid‐Diaphyseal Fracture Model of the Feline Radius and Ulna          下载免费PDF全文

Timothy J. Preston  Mark Glyde  Giselle Hosgood  Robert E. Day 《Veterinary surgery : VS》2016,45(3):289-294

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Chemistry Nobel rich in structure     

Seringhaus M  Gerstein M 《Science (New York, N.Y.)》2007,315(5808):40-41

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Comparison of two doses of recombinant human bone morphogenetic protein in absorbable collagen sponges for bone healing in dogs     

Schmiedt CW  Lu Y  Heaney K  Muir P  Amodie DM  Markel MD 《American journal of veterinary research》2007,68(8):834-840

OBJECTIVE: To determine the effects of 2 doses of recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge (rhBMP-2/ACS) on bone healing in dogs. ANIMALS: 27 adult dogs. PROCEDURES: Dogs underwent a mid-diaphyseal (1-mm) tibial osteotomy (stabilized with external skeletal fixation) and received an ACS containing 0.28 mg (0.2 mg/mL) or 0.56 mg (0.4 mg/mL) of rhBMP-2 or no treatment (control dogs). All dogs were examined daily; bone healing was assessed via radiography and subjective lameness evaluation every 2 weeks. After euthanasia at 8 weeks, tibiae were evaluated biomechanically and histologically. RESULTS: Control dogs required antimicrobial treatment for pin-site-related complications more frequently than did rhBMP-2/ACS-treated dogs. At 4 and 6 weeks, weight bearing was greater in dogs treated with rhBMP-2/ACS (0.2 mg/mL) than in control dogs, albeit not significantly. Compared with control treatment, both doses of rhBMP-2/ACS accelerated osteotomy healing at 4, 6, and 8 weeks, and the 0.2 mg/mL dose enhanced healing at 2 weeks; healing at 6 weeks was greater for the lower-dose treatment than for the higher-dose treatment. Histologically, healing at 8 weeks was significantly improved for both rhBMP-2/ACS treatments, compared with control treatment. Among groups, biomechanical variables did not differ, although less osteotomy-site failures occurred in rhBMP-2/ACS-treated groups. CONCLUSIONS AND CLINICAL RELEVANCE: In dogs that underwent tibial osteotomy, rhBMP-2/ACS (0.2 mg/mL) appeared to accelerate bone healing and reduce lameness (compared with control treatment) and apparently augmented bone healing more than rhBMP-2/ACS (0.4 mg/mL). Compared with control dogs, rhBMP-2/ACS-treated dogs required antimicrobial treatments less frequently.  相似文献   

Clinical characteristics and mode of inheritance of familial focal seizures in Standard Poodles     

Licht BG  Lin S  Luo Y  Hyson LL  Licht MH  Harper KM  Sullivan SA  Fernandez SA  Johnston EV 《Journal of the American Veterinary Medical Association》2007,231(10):1520-1528

OBJECTIVE: To determine clinical characteristics and mode of inheritance of seizures in a family of Standard Poodles. DESIGN: Case series. ANIMALS: 90 Standard Poodles descended from the same maternal bloodline (30 with probable idiopathic epilepsy [PIE] and 60 without any history of seizures). PROCEDURES: Researchers contacted owners to determine whether dogs had ever had any seizures and, if so, the nature of any such seizures and any potential underlying causes. Dogs were considered to have PIE if they were between 6 months and 7.5 years old at the time of seizure onset and had no evidence of any underlying cause. To determine the mode of inheritance, segregation analyses were designed to allow the family to be analyzed as a whole, as opposed to as nuclear families. Competing models of inheritance were compared statistically for their ability to explain the data. RESULTS: Of the dogs with PIE, 28 (93%) had focal onset seizures with or without secondary generalization. Median age of onset was 3.7 years; 6 dogs were > 5 years old at the onset of seizures. Segregation analyses strongly suggested that PIE was inherited as a simple recessive autosomal trait with complete or almost complete penetrance. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that in this family of Standard Poodles, PIE was inherited as a simple recessive autosomal trait with complete or almost complete penetrance. Seizures often had focal, as opposed to generalized, onsets, and it was not uncommon for seizures to begin after 5 years of age.  相似文献   

Seroprevalence of and agroecological risk factors for Mycobacterium avium subspecies paratuberculosis and neospora caninum infection among adult beef cattle in cow-calf herds in Alberta, Canada     

Scott HM  Sorensen O  Wu JT  Chow EY  Manninen K 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(4):397-406

A province-wide cross-sectional seroprevalence and agroecological risk factor study of Mycobacterium avium subspecies paratuberculosis (MAP) and Neospora caninum (NC) infection among cattle in 100 cow-calf herds in Alberta was conducted. The seroprevalence of MAP in adult cattle was 1.5% across all herds. Using a widely accepted herd test cutpoint of 2 or more seropositive cows out of 30 animals tested, 7.9% of herds were estimated to be infected (95% confidence interval (CI): 2.3-23.4%). Seroprevalence of MAP differed by agroecological region; specifically, cattle and herds in areas with high soil pH (> 7.0), southern latitudes, and arid climates had a moderately reduced risk of infection (P < 0.10). Seroprevalence of NC infection was 9.7% among adult beef cattle province-wide--these levels also varied by agroecological region--with 91.0% of herds infected overall.  相似文献   

Molecular and serologic characterization, pathogenicity, and protection studies with infectious bronchitis virus field isolates from California   总被引：6，自引：0，他引：6  

Jackwood MW  Hilt DA  Williams SM  Woolcock P  Cardona C  O'Connor R 《Avian diseases》2007,51(2):527-533

In this study, we characterized three variant infectious bronchitis virus (IBV) strains isolated in 2003 and 2004 from broiler chickens in California and compared them to previously isolated California variant viruses and to common vaccine serotypes used in the United States. We conducted genetic, serologic, and pathogenicity studies on all three isolates, then tested different vaccines against one of the viruses. Genetically the three variant IBV strains, designated CA557/03, CA706/03, and CA1737/04, were not related to each other. GenBank BLAST database search and phylogenetic analysis of the hypervariable region of the S1 subunit of the spike gene to determine the most closely related viruses to the three variants showed the CA557/03 variant to be 81.8% similar to the CAV/CA56b/91 whereas the CA706/03 and CA1737/04 variant viruses were only distantly related to Dutch/D1466/81 (72.2%), a vaccine strain used in Europe, and Korea/K142/02 (72.7%), a Korean field isolate, respectively. Cross virus-neutralization testing showed that none of the 2003-04 California IBV variant viruses were serologically related to each other or to Ark, Conn, or Mass vaccine strains. In addition the CA1737/04 isolate was also tested against DE072 and found not to be serologically related. All three variant viruses were pathogenic in 1-wk-old broilers and vaccination with Mass/Conn followed by Holland/Conn provided 80% protection against the CA1737/04 virus. The 2003-04 California variant viruses were not compared with variants isolated in California during 1970s and 1980s because, to our knowledge, no genetic information is available and those viruses are no longer obtainable. This study shows that the CA557/03 virus was distantly related to the CAV-type viruses isolated in California in the early 1990s, but that none of the 2003-04 viruses were similar genetically or serologically to the CAL99-type viruses, indicating that new IBV variants continue to emerge and cause disease in commercial chickens in California.  相似文献