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排序方式: 共有91条查询结果,搜索用时 31 毫秒
51.
Seasonal change in collagen content of red seabream muscle 总被引:1,自引:0,他引:1
52.
Kobayashi Takeshi Nishitake Mayu Saito Masataka Terahara Takeshi Imada Chiaki Shinagawa Akira Takeshita Atsuko 《Fisheries Science》2020,86(4):721-728
Fisheries Science - We analyzed the bacterial flora and chemical properties of the Japanese traditional anchovy product called salted Etari, which is distributed in Nagasaki Prefecture in the... 相似文献
53.
Hiroyuki Enari Yoshinori Takahashi Masataka Kawarasaki Motohiko Tada Kuniaki Tatsuta 《Fisheries Science》2008,74(4):911-920
ABSTRACT: The salmon peptide digested from salmon muscle showed a strong inhibitory activity against the angiotensin I-converting enzyme (ACE). The antihypertensive effect of the salmon peptide on spontaneously hypertensive rats (SHR) was examined. After the single intravenous administration of the salmon peptide at a dose of 30 mg/kg body weight, the systolic blood pressure (SBP) was significantly reduced against the control. Further, a double-blind, placebo-controlled, parallel-group study determined the efficacy of the salmon peptide in mild hypertensive subjects. The SBP, after a 1.0 g of salmon peptide intake, was significantly reduced at 4 weeks after the intake, and 2 weeks after the intake finished, compared to the value before ingestion. Bioassay-guided separation of the salmon peptide, using a combination of column chromatographic techniques, led to the identification of 20 active di- and tri-peptides, including Ile-Val-Phe and Phe-Ile-Ala as two new ACE inhibitory tripeptides. Ile-Trp had the strongest ACE inhibitory activity (IC50 = 1.2 μM) in vitro , and contributed 5.2% to the total ACE inhibitory activity. The salmon peptide and Ile-Trp showed a digestive resistance by in vitro assay, which mimicked the digestive organ, and had no affinity for factors related to blood pressure regulation, except for the ACE inhibitory activity. 相似文献
54.
The rate of sugar formation from aspartate-14C(U) and alanine-L-14C was examined under various light intensities in three C4-plants. The results obtained were as follows. The rates of sugar formation from aspartate-14C(U) became larger in the following order, Paspalum urvillei, Egragrostis ferrunginea, and Zoysia japonica. This order agreed well with the order of their photosynthetic rates measured by gas analyzer. In all the C4-plants, there were three steps in the sugar formation curve from aspartate-14C(U). At first, sugar linearly increased with an increase in the light intensity up to 20 klux. Second, from 20 to 40 klux, it hardly increased with an increase in the light intensity. Third, above 40 klux, it increased linearly again. On the other hand, the plateau did not exist between 20 and 40 klux in the sugar formation curves from alanine-l-14C in any of the cases, and sugar continued to increase with an increase in the light intensity up to 80 klux. At low light intensities, the amount of CO2 released from aspartate-14C(U) and alanine-l-14C correlated well with the magnitude of the dark respiration in the C4-plants. At a high light intensity, however, CO2 release closely correlated with the thickness of mesophyll layers surrounding the vascular bundle sheath. The thicker the mesophyll layers were, the smaller the release of CO2 became. From this evidence, we conclude that the mesophyll layers play a vital role in refixation of the internal CO2 in the light. 相似文献
55.
This is the first report of TRPA1 activation by fatty acids. Activation of TRPA1 and TRPV1 induces thermogenesis and energy expenditure enhancement. In this study, we searched for novel agonists of TRPA1 and TRPV1 from a nonpungent food, royal jelly (RJ). We measured the activation of human TRPA1 and TRPV1 by RJ extracts and found that the hexane extract contains TRPA1 agonists. The main functional compounds in the hexane extract were trans-10-hydroxy-2-decenoic acid (HDEA) and 10-hydroxydecanoic acid (HDAA). These are characteristic fatty acids of RJ. Their EC50 values were about 1,000 times larger than that of AITC, and their maximal responses were equal. They activated TRPA1 more strongly than TRPV1. Their EC50 values for TRPV1 were 2 times larger, and the maximal response was less than half of that for TRPA1. Next, we studied the potencies of other lipid components for both receptors. Most of them have higher affinity to TRPA1 than TRPV1. Among them, dicarboxylic acids showed equal efficacy for both receptors, but those are present in only small amounts in RJ. We concluded that the main function of RJ is TRPA1 activation by HDEA and HDAA, the major components of the RJ lipid fraction. 相似文献
56.
Reale F Parenti S Reeves KK Weber M Bobra MG Barbera M Kano R Narukage N Shimojo M Sakao T Peres G Golub L 《Science (New York, N.Y.)》2007,318(5856):1582-1585
The determination of the fine thermal structure of the solar corona is fundamental to constraining the coronal heating mechanisms. The Hinode X-ray Telescope collected images of the solar corona in different passbands, thus providing temperature diagnostics through energy ratios. By combining different filters to optimize the signal-to-noise ratio, we observed a coronal active region in five filters, revealing a highly thermally structured corona: very fine structures in the core of the region and on a larger scale further away. We observed continuous thermal distribution along the coronal loops, as well as entangled structures, and variations of thermal structuring along the line of sight. 相似文献
57.
Ken-ichi?Kaneko Masataka?Satomi Meiko?Kimura Hisanori?Nozawa Nobuo?SekiEmail author 《Fisheries Science》2005,71(5):1167-1173
ABSTRACT: Adductor muscles dissected from live scallop Patinopecten yessoensis were stored in oxygenated artificial sea water. The initial muscle adenosine triphosphate (ATP) level, approximately 7.5 µmol/g, remained longer at 5°C than at either 0 or 10°C. The pH of sea water decreased continuously and the consumption of dissolved oxygen increased even after muscle ATP was almost exhausted. The number of viable microbes, measured as colony-forming units (c.f.u.) in the muscle, increased to reach a plateau at approximately 107 −108 c.f.u./g, while muscle ATP remained at high levels. After this time, muscle ATP sharply decreased. Antibiotics or sorbate added into the oxygenated sea water effectively inhibited both the growth of microbes and the decrease in the pH of sea water. Under these conditions, the retention period of muscle ATP was greatly extended. Thus, it seems most likely that scallop adductor muscle cells are suffocated by the limitation of oxygen supply caused by aerobic microbes grown on the surface of muscle tissue. 相似文献
58.
Taiko Oda Jinzhong Xu Ayako Fujita Masataka Mochizuki Michio Namikoshi 《Marine drugs》2006,4(1):22-27
Bioassay-guided isolation from the ethanol extract of a marine sponge Theonella sp. collected in Palau yielded bistheonellide A, which strongly inhibited the colony formation of Chinese hamster V79 cells (EC50 = 6.8 nM). Bistheonellide A is an actin-polymerization inhibitor and was suggested to control cytokine production. Therefore, we attempted to detect an effect of this compound on IL-8 production in PMA-stimulated HL-60 cells. Interestingly, bistheonellide A did not modulate the production of IL-8 under cytotoxic concentrations as determined by LDH analysis. Although the correlation between the inhibition of microtubule assembly and the stimulation of IL-8 production has been observed for several compounds, the polymerization of actin was not related to an IL-8 production in the case of bistheonellide A. It will be suggested that the actin polymerization is not involved in the IL-8 production system. 相似文献
59.
Taiko Oda Takeshi Fujiwara Hongwei Liu Kazuyo Ukai Remy E. P. Mangindaan Masataka Mochizuki Michio Namikoshi 《Marine drugs》2006,4(1):15-21
The effects of seven compounds 1–7, isolated from a tropical ascidian Lissoclinum cf. badium, on IL-8 production in PMA-stimulated HL-60 cells were examined. Lissoclibadins 2 (2) and 3 (3) and lissoclinotoxin F (5) increased the IL-8 production in a dose-dependent manner. Compounds 2 and 5 are structural isomers possessing dimeric structures of trans and cis-orientations, respectively, and showed a very similar activity on the induction of IL-8 levels. Compound 3 and lissoclinotoxin E (4) are also structural isomers having dimeric trans and cis-structures, respectively, but 4 did not induce the IL-8 production. Lissoclibadin 1 (1, trimeric compound) and two monomeric compounds (6 and 7) did not increase the IL-8 level. Therefore, the differences in their structures remarkably affected the IL-8 production activity, the inhibition of cell proliferation, and the survival of HL-60 cells. Lissoclibadin 2 was the most interesting compound of the seven metabolites tested in this study. 相似文献
60.
Yosuke Kadomae Yasuhide Maruyama Masataka Sugimoto Takashi Taniguchi Kiyohito Koyama 《Fibers and Polymers》2009,10(3):275-279
Electrospun atactic polypropylene (PP) fibers are thicker than those obtained from isotactic PP, although the viscosity of
molten PPs is almost same. Thus we focused on the effect of tacticity of PP on fiber diameters. The PP samples with various
tacticity were prepared by changing the blend ratio of isotactic PP and atactic PP. Melt-electrospinning is performed by using
blended samples, and then electrospun fibers were observed by scanning electron microscope to evaluate fiber diameter of obtained
fibers. It is clear that the diameter of electrospun PP fibers decreases as high tacticity content of PP increases. This result
suggests that tacticity of samples is an important factor to control the electrospun fiber diameter. 相似文献